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Q92925

- SMRD2_HUMAN

UniProt

Q92925 - SMRD2_HUMAN

Protein

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

Gene

SMARCD2

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 116 (01 Oct 2014)
      Sequence version 3 (08 Feb 2011)
      Previous versions | rss
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    Functioni

    Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology).

    GO - Molecular functioni

    1. protein binding Source: IntAct
    2. transcription coactivator activity Source: UniProtKB

    GO - Biological processi

    1. ATP-dependent chromatin remodeling Source: UniProt
    2. chromatin remodeling Source: BHF-UCL
    3. nucleosome disassembly Source: BHF-UCL
    4. regulation of transcription from RNA polymerase II promoter Source: UniProtKB
    5. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Molecular functioni

    Chromatin regulator

    Keywords - Biological processi

    Transcription, Transcription regulation

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2
    Alternative name(s):
    60 kDa BRG-1/Brm-associated factor subunit B
    BRG1-associated factor 60B
    Short name:
    BAF60B
    Gene namesi
    Name:SMARCD2
    Synonyms:BAF60B
    ORF Names:PRO2451
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 17

    Organism-specific databases

    HGNCiHGNC:11107. SMARCD2.

    Subcellular locationi

    GO - Cellular componenti

    1. nuclear chromatin Source: UniProt
    2. nucleus Source: HPA
    3. protein complex Source: UniProt
    4. SWI/SNF complex Source: UniProtKB

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA35957.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 531531SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2PRO_0000071985Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei217 – 2171Phosphothreonine4 Publications

    Post-translational modificationi

    Ubiquitinated through a signaling process involving RAC1 and the RING finger protein UNKL.1 Publication

    Keywords - PTMi

    Phosphoprotein, Ubl conjugation

    Proteomic databases

    MaxQBiQ92925.
    PaxDbiQ92925.
    PRIDEiQ92925.

    PTM databases

    PhosphoSiteiQ92925.

    Expressioni

    Tissue specificityi

    Isoform 2 is expressed in the pancreas.1 Publication

    Gene expression databases

    ArrayExpressiQ92925.
    BgeeiQ92925.
    CleanExiHS_SMARCD2.
    GenevestigatoriQ92925.

    Organism-specific databases

    HPAiHPA051173.

    Interactioni

    Subunit structurei

    Component of the BAF complex, which includes at least actin (ACTB), ARID1A, ARID1B/BAF250, SMARCA2, SMARCA4/BRG1, ACTL6A/BAF53, ACTL6B/BAF53B, SMARCE1/BAF57, SMARCC1/BAF155, SMARCC2/BAF170, SMARCB1/SNF5/INI1, and one or more of SMARCD1/BAF60A, SMARCD2/BAF60B, or SMARCD3/BAF60C. In muscle cells, the BAF complex also contains DPF3. May interact with SMARCA4, the catalytic subunit of the SWI/SNF related nucleosome-remodeling complexes BRG1(I) and BRG1(II). The precise distribution of the related SMARCD1, SMARCD2 and SMARCD3 proteins among these and other SWI/SNF nucleosome-remodeling complexes is not fully known. Interacts with UNKL.2 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    UNKLQ9H9P52EBI-358441,EBI-7797561

    Protein-protein interaction databases

    BioGridi112487. 27 interactions.
    DIPiDIP-31182N.
    IntActiQ92925. 16 interactions.
    MINTiMINT-1138034.
    STRINGi9606.ENSP00000392617.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92925.
    SMRiQ92925. Positions 307-386.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini307 – 38276SWIBAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi10 – 129120Pro-richAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SMARCD family.Curated
    Contains 1 SWIB domain.Curated

    Phylogenomic databases

    eggNOGiCOG5531.
    HOVERGENiHBG054046.
    KOiK11650.
    OMAiMRFSEIP.
    OrthoDBiEOG7PZRXG.
    PhylomeDBiQ92925.
    TreeFamiTF106486.

    Family and domain databases

    Gene3Di1.10.245.10. 1 hit.
    InterProiIPR003121. SWIB_MDM2_domain.
    [Graphical view]
    PfamiPF02201. SWIB. 1 hit.
    [Graphical view]
    SUPFAMiSSF47592. SSF47592. 1 hit.

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q92925-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MSGRGAGGFP LPPLSPGGGA VAAALGAPPP PAGPGMLPGP ALRGPGPAGG    50
    VGGPGAAAFR PMGPAGPAAQ YQRPGMSPGN RMPMAGLQVG PPAGSPFGAA 100
    APLRPGMPPT MMDPFRKRLL VPQAQPPMPA QRRGLKRRKM ADKVLPQRIR 150
    ELVPESQAYM DLLAFERKLD QTIARKRMEI QEAIKKPLTQ KRKLRIYISN 200
    TFSPSKAEGD SAGTAGTPGG TPAGDKVASW ELRVEGKLLD DPSKQKRKFS 250
    SFFKSLVIEL DKELYGPDNH LVEWHRMPTT QETDGFQVKR PGDLNVKCTL 300
    LLMLDHQPPQ YKLDPRLARL LGVHTQTRAA IMQALWLYIK HNQLQDGHER 350
    EYINCNRYFR QIFSCGRLRF SEIPMKLAGL LQHPDPIVIN HVISVDPNDQ 400
    KKTACYDIDV EVDDPLKAQM SNFLASTTNQ QEIASLDVKI HETIESINQL 450
    KTQRDFMLSF STDPQDFIQE WLRSQRRDLK IITDVIGNPE EERRAAFYHQ 500
    PWAQEAVGRH IFAKVQQRRQ ELEQVLGIRL T 531

    Note: No experimental confirmation available.

    Length:531
    Mass (Da):58,921
    Last modified:February 8, 2011 - v3
    Checksum:i8C92168AE7782814
    GO
    Isoform 2 (identifier: Q92925-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         48-68: Missing.
         86-123: GLQVGPPAGS...PFRKRLLVPQ → RLAGGTPCWL...SIPKTPACAP

    Note: Produced by aberrant splicing sites.

    Show »
    Length:510
    Mass (Da):57,244
    Checksum:iB44CF9CA48DB6065
    GO
    Isoform 3 (identifier: Q92925-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-71: MSGRGAGGFP...MGPAGPAAQY → MGRRVGVEVTPRWAPQKCQGARP

    Show »
    Length:483
    Mass (Da):55,239
    Checksum:iF81547E527C34871
    GO

    Sequence cautioni

    The sequence AAC50696.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence AAF20280.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti11 – 111L → V in AAC50696. (PubMed:8804307)Curated
    Sequence conflicti28 – 281P → Q in AAI42964. (PubMed:15489334)Curated
    Sequence conflicti269 – 2691N → G in AAC50696. (PubMed:8804307)Curated
    Sequence conflicti275 – 2762HR → YW in AAC50696. (PubMed:8804307)Curated
    Sequence conflicti332 – 3321M → T in AAI42964. (PubMed:15489334)Curated
    Sequence conflicti369 – 3691R → S in AAI42964. (PubMed:15489334)Curated
    Sequence conflicti372 – 3721E → K in AAI42964. (PubMed:15489334)Curated
    Sequence conflicti486 – 4861I → T in AAC50696. (PubMed:8804307)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 7171MSGRG…PAAQY → MGRRVGVEVTPRWAPQKCQG ARP in isoform 3. 1 PublicationVSP_040530Add
    BLAST
    Alternative sequencei48 – 6821Missing in isoform 2. 1 PublicationVSP_040531Add
    BLAST
    Alternative sequencei86 – 12338GLQVG…LLVPQ → RLAGGTPCWLPIWCSSSAST WHPTHHDGSIPKTPACAP in isoform 2. 1 PublicationVSP_040532Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U66618 mRNA. Translation: AAC50696.1. Different initiation.
    AK300939 mRNA. Translation: BAG62568.1.
    AK303951 mRNA. Translation: BAG64878.1.
    AC015651 Genomic DNA. No translation available.
    CH471109 Genomic DNA. Translation: EAW94267.1.
    BC018953 mRNA. Translation: AAH18953.2.
    BC142963 mRNA. Translation: AAI42964.1.
    AF113019 mRNA. Translation: AAF20280.1. Different initiation.
    CCDSiCCDS45756.1. [Q92925-1]
    RefSeqiNP_001091896.1. NM_001098426.1. [Q92925-1]
    UniGeneiHs.250581.

    Genome annotation databases

    EnsembliENST00000323347; ENSP00000318451; ENSG00000108604. [Q92925-3]
    ENST00000448276; ENSP00000392617; ENSG00000108604. [Q92925-1]
    GeneIDi6603.
    KEGGihsa:6603.
    UCSCiuc010dea.1. human. [Q92925-1]
    uc010wpt.1. human. [Q92925-3]

    Polymorphism databases

    DMDMi322510105.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U66618 mRNA. Translation: AAC50696.1 . Different initiation.
    AK300939 mRNA. Translation: BAG62568.1 .
    AK303951 mRNA. Translation: BAG64878.1 .
    AC015651 Genomic DNA. No translation available.
    CH471109 Genomic DNA. Translation: EAW94267.1 .
    BC018953 mRNA. Translation: AAH18953.2 .
    BC142963 mRNA. Translation: AAI42964.1 .
    AF113019 mRNA. Translation: AAF20280.1 . Different initiation.
    CCDSi CCDS45756.1. [Q92925-1 ]
    RefSeqi NP_001091896.1. NM_001098426.1. [Q92925-1 ]
    UniGenei Hs.250581.

    3D structure databases

    ProteinModelPortali Q92925.
    SMRi Q92925. Positions 307-386.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 112487. 27 interactions.
    DIPi DIP-31182N.
    IntActi Q92925. 16 interactions.
    MINTi MINT-1138034.
    STRINGi 9606.ENSP00000392617.

    PTM databases

    PhosphoSitei Q92925.

    Polymorphism databases

    DMDMi 322510105.

    Proteomic databases

    MaxQBi Q92925.
    PaxDbi Q92925.
    PRIDEi Q92925.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000323347 ; ENSP00000318451 ; ENSG00000108604 . [Q92925-3 ]
    ENST00000448276 ; ENSP00000392617 ; ENSG00000108604 . [Q92925-1 ]
    GeneIDi 6603.
    KEGGi hsa:6603.
    UCSCi uc010dea.1. human. [Q92925-1 ]
    uc010wpt.1. human. [Q92925-3 ]

    Organism-specific databases

    CTDi 6603.
    GeneCardsi GC17M061909.
    H-InvDB HIX0014075.
    HGNCi HGNC:11107. SMARCD2.
    HPAi HPA051173.
    MIMi 601736. gene.
    neXtProti NX_Q92925.
    PharmGKBi PA35957.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5531.
    HOVERGENi HBG054046.
    KOi K11650.
    OMAi MRFSEIP.
    OrthoDBi EOG7PZRXG.
    PhylomeDBi Q92925.
    TreeFami TF106486.

    Miscellaneous databases

    ChiTaRSi SMARCD2. human.
    GeneWikii SMARCD2.
    GenomeRNAii 6603.
    NextBioi 25689.
    PROi Q92925.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q92925.
    Bgeei Q92925.
    CleanExi HS_SMARCD2.
    Genevestigatori Q92925.

    Family and domain databases

    Gene3Di 1.10.245.10. 1 hit.
    InterProi IPR003121. SWIB_MDM2_domain.
    [Graphical view ]
    Pfami PF02201. SWIB. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47592. SSF47592. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Diversity and specialization of mammalian SWI/SNF complexes."
      Wang W., Xue Y., Zhou S., Kuo A., Cairns B.R., Crabtree G.R.
      Genes Dev. 10:2117-2130(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2), TISSUE SPECIFICITY.
    2. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3).
      Tissue: Small intestine and Trachea.
    3. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
      Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
      , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
      Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Tissue: Uterus.
    6. "Functional prediction of the coding sequences of 14 new genes deduced by analysis of cDNA clones from human fetal liver."
      Zhang C., Yu Y., Zhang S., Ouyang S., Luo L., Wei H., Zhou G., Liu M., He F.
      Submitted (DEC-1998) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 450-531.
      Tissue: Fetal liver.
    7. "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A., Villen J., Gerber S.A., Rush J., Gygi S.P.
      Nat. Biotechnol. 24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-217, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-217, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    9. "Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach."
      Gauci S., Helbig A.O., Slijper M., Krijgsveld J., Heck A.J., Mohammed S.
      Anal. Chem. 81:4493-4501(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    10. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
      Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Leukemic T-cell.
    11. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
      Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    12. "The SWI/SNF protein BAF60b is ubiquitinated through a signalling process involving Rac GTPase and the RING finger protein Unkempt."
      Lores P., Visvikis O., Luna R., Lemichez E., Gacon G.
      FEBS J. 277:1453-1464(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH UNKL, UBIQUITINATION.
    13. "Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex."
      Lange M., Kaynak B., Forster U.B., Toenjes M., Fischer J.J., Grimm C., Schlesinger J., Just S., Dunkel I., Krueger T., Mebus S., Lehrach H., Lurz R., Gobom J., Rottbauer W., Abdelilah-Seyfried S., Sperling S.
      Genes Dev. 22:2370-2384(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN THE BAF COMPLEX, IDENTIFICATION BY MASS SPECTROMETRY.
    14. "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V., Vermeulen M., Santamaria A., Kumar C., Miller M.L., Jensen L.J., Gnad F., Cox J., Jensen T.S., Nigg E.A., Brunak S., Mann M.
      Sci. Signal. 3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-217, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.
    15. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    16. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
      Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-217, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSMRD2_HUMAN
    AccessioniPrimary (citable) accession number: Q92925
    Secondary accession number(s): A5PLL5
    , A6NNQ7, B4DV56, B4E1R6, Q7L2I6, Q9UHZ1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 4, 2005
    Last sequence update: February 8, 2011
    Last modified: October 1, 2014
    This is version 116 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 17
      Human chromosome 17: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3