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Q928R9

- DCEB_LISIN

UniProt

Q928R9 - DCEB_LISIN

Protein

Glutamate decarboxylase beta

Gene

gadB

Organism
Listeria innocua serovar 6a (strain CLIP 11262)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 71 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Converts internalized glutamate to GABA and increases the internal pH. Involved in glutamate-dependent acid resistance in gastric fluid By similarity.By similarity

    Catalytic activityi

    L-glutamate = 4-aminobutanoate + CO2.

    Cofactori

    Pyridoxal phosphate.By similarity

    GO - Molecular functioni

    1. glutamate decarboxylase activity Source: UniProtKB-EC
    2. pyridoxal phosphate binding Source: InterPro

    GO - Biological processi

    1. glutamate metabolic process Source: InterPro

    Keywords - Molecular functioni

    Decarboxylase, Lyase

    Keywords - Ligandi

    Pyridoxal phosphate

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamate decarboxylase beta (EC:4.1.1.15)
    Short name:
    GAD-beta
    Gene namesi
    Name:gadB
    Ordered Locus Names:lin2463
    OrganismiListeria innocua serovar 6a (strain CLIP 11262)
    Taxonomic identifieri272626 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
    ProteomesiUP000002513: Chromosome

    Organism-specific databases

    GenoListiLIN2463.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 464464Glutamate decarboxylase betaPRO_0000146989Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei275 – 2751N6-(pyridoxal phosphate)lysineBy similarity

    Interactioni

    Protein-protein interaction databases

    STRINGi272626.lin2463.

    Structurei

    3D structure databases

    ProteinModelPortaliQ928R9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the group II decarboxylase family.Curated

    Phylogenomic databases

    eggNOGiCOG0076.
    HOGENOMiHOG000070228.
    KOiK01580.
    OMAiPTFQINF.
    OrthoDBiEOG6TFCPW.

    Family and domain databases

    Gene3Di3.40.640.10. 1 hit.
    InterProiIPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view]
    PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
    PfamiPF00282. Pyridoxal_deC. 1 hit.
    [Graphical view]
    SUPFAMiSSF53383. SSF53383. 1 hit.
    TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q928R9-1 [UniParc]FASTAAdd to Basket

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    MLYSKENKES YLEPVFGSSA EDRDIPKYTL AKEPLEPRIA YRLVKDELLD    50
    EGSARQNLAT FCQTYMEDEA TKLMSETLEK NAIDKSEYPR TAELENRCVN 100
    IIADLWHAPK DQKFMGTSTI GSSEACMLGG MAMKFAWRKR AEKLGLDIYA 150
    QKPNLVISSG YQVCWEKFCV YWDIDMRVVP MDKDHMQLNT DQVLDYVDEY 200
    TIGVVGILGI TYTGRYDDIY ALNEKLEEYN SKTDYKVYIH VDAASGGFFT 250
    PFVEPDIIWD FRLKNVISIN TSGHKYGLVY PGIGWVLWKD ESYLPEELIF 300
    KVSYLGGEMP TMQINFSRSA SHIIGQYYNF LRYGFEGYRT IHQKTSDVAQ 350
    YLAHAVEQTG YFDIYNDGSH LPIVCYKLKD DANVKWTLYD LADRLQMRGW 400
    QVPAYPLPKN LENIIIQRYV CRADLGFNMA EEFIQDFQAS IQELNNAHIL 450
    FHDTQQSGVH GFTH 464
    Length:464
    Mass (Da):53,600
    Last modified:December 1, 2001 - v1
    Checksum:i4C35CD1395ADF481
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596172 Genomic DNA. Translation: CAC97690.1.
    PIRiAB1740.
    RefSeqiNP_471793.1. NC_003212.1.

    Genome annotation databases

    EnsemblBacteriaiCAC97690; CAC97690; CAC97690.
    GeneIDi1131252.
    KEGGilin:lin2463.
    PATRICi20301779. VBILisInn102668_2522.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL596172 Genomic DNA. Translation: CAC97690.1 .
    PIRi AB1740.
    RefSeqi NP_471793.1. NC_003212.1.

    3D structure databases

    ProteinModelPortali Q928R9.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 272626.lin2463.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAC97690 ; CAC97690 ; CAC97690 .
    GeneIDi 1131252.
    KEGGi lin:lin2463.
    PATRICi 20301779. VBILisInn102668_2522.

    Organism-specific databases

    GenoListi LIN2463.

    Phylogenomic databases

    eggNOGi COG0076.
    HOGENOMi HOG000070228.
    KOi K01580.
    OMAi PTFQINF.
    OrthoDBi EOG6TFCPW.

    Family and domain databases

    Gene3Di 3.40.640.10. 1 hit.
    InterProi IPR010107. Glutamate_decarboxylase.
    IPR002129. PyrdxlP-dep_de-COase.
    IPR015424. PyrdxlP-dep_Trfase.
    IPR015421. PyrdxlP-dep_Trfase_major_sub1.
    [Graphical view ]
    PANTHERi PTHR11999:SF1. PTHR11999:SF1. 1 hit.
    Pfami PF00282. Pyridoxal_deC. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53383. SSF53383. 1 hit.
    TIGRFAMsi TIGR01788. Glu-decarb-GAD. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: CLIP 11262.

    Entry informationi

    Entry nameiDCEB_LISIN
    AccessioniPrimary (citable) accession number: Q928R9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2002
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 71 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3