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Q928R9 (DCEB_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glutamate decarboxylase beta

Short name=GAD-beta
EC=4.1.1.15
Gene names
Name:gadB
Ordered Locus Names:lin2463
OrganismListeria innocua serovar 6a (strain CLIP 11262) [Complete proteome] [HAMAP]
Taxonomic identifier272626 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length464 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Converts internalized glutamate to GABA and increases the internal pH. Involved in glutamate-dependent acid resistance in gastric fluid By similarity.

Catalytic activity

L-glutamate = 4-aminobutanoate + CO2.

Cofactor

Pyridoxal phosphate By similarity.

Sequence similarities

Belongs to the group II decarboxylase family.

Ontologies

Keywords
   LigandPyridoxal phosphate
   Molecular functionDecarboxylase
Lyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglutamate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functionglutamate decarboxylase activity

Inferred from electronic annotation. Source: UniProtKB-EC

pyridoxal phosphate binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 464464Glutamate decarboxylase beta
PRO_0000146989

Amino acid modifications

Modified residue2751N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q928R9 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 4C35CD1395ADF481

FASTA46453,600
        10         20         30         40         50         60 
MLYSKENKES YLEPVFGSSA EDRDIPKYTL AKEPLEPRIA YRLVKDELLD EGSARQNLAT 

        70         80         90        100        110        120 
FCQTYMEDEA TKLMSETLEK NAIDKSEYPR TAELENRCVN IIADLWHAPK DQKFMGTSTI 

       130        140        150        160        170        180 
GSSEACMLGG MAMKFAWRKR AEKLGLDIYA QKPNLVISSG YQVCWEKFCV YWDIDMRVVP 

       190        200        210        220        230        240 
MDKDHMQLNT DQVLDYVDEY TIGVVGILGI TYTGRYDDIY ALNEKLEEYN SKTDYKVYIH 

       250        260        270        280        290        300 
VDAASGGFFT PFVEPDIIWD FRLKNVISIN TSGHKYGLVY PGIGWVLWKD ESYLPEELIF 

       310        320        330        340        350        360 
KVSYLGGEMP TMQINFSRSA SHIIGQYYNF LRYGFEGYRT IHQKTSDVAQ YLAHAVEQTG 

       370        380        390        400        410        420 
YFDIYNDGSH LPIVCYKLKD DANVKWTLYD LADRLQMRGW QVPAYPLPKN LENIIIQRYV 

       430        440        450        460 
CRADLGFNMA EEFIQDFQAS IQELNNAHIL FHDTQQSGVH GFTH 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL596172 Genomic DNA. Translation: CAC97690.1.
PIRAB1740.
RefSeqNP_471793.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ928R9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272626.lin2463.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC97690; CAC97690; CAC97690.
GeneID1131252.
KEGGlin:lin2463.
PATRIC20301779. VBILisInn102668_2522.

Organism-specific databases

GenoListLIN2463.
CMRSearch...

Phylogenomic databases

eggNOGCOG0076.
HOGENOMHOG000070228.
KOK01580.
OMAPTFQINF.
OrthoDBEOG6TFCPW.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
InterProIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
TIGRFAMsTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetSearch...

Entry information

Entry nameDCEB_LISIN
AccessionPrimary (citable) accession number: Q928R9
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families