Reviewed, UniProtKB/Swiss-Prot Q928P3 (FENR2_LISIN)

Names and origin

Protein names

Recommended name:
    Ferredoxin--NADP reductase 2
      Short name=Fd-NADP+ reductase 2
      Short name=FNR 2
    EC=1.18.1.2

Gene names

Ordered Locus Names:

lin2489

Organism

Listeria innocua [Complete proteome] [HAMAP]

Taxonomic identifier

1642 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length	331 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: HAMAP NADP or NADPH binding Inferred from electronic annotation. Source: HAMAP ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 331	331	Ferredoxin--NADP reductase 2 HAMAP MF_01685		PRO_0000364870
Sites
	Binding site	37	1	FAD By similarity
	Binding site	45	1	FAD By similarity
	Binding site	50	1	FAD By similarity
	Binding site	90	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	124	1	FAD; via amide nitrogen By similarity
	Binding site	286	1	FAD By similarity
	Binding site	327	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q928P3-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: BF4E63C0110D7E94	FASTA	331	36,511
	10 20 30 40 50 60 MDEKTKIYDI TIIGGGPVGL FAAFYAGMRN ASVKIIESLP QLGGQLSTLY PEKYIYDIPG 70 80 90 100 110 120 YPSVRAQELV NNLIQQMKPF DPTVALEEAV QSVEKQVDGT FEIITKKDTH YSKAIIITAG 130 140 150 160 170 180 NGAFEPRRLD LPEAEQYEGK NIHYFINDLS RFSGRRVAVC GGGDSAVDWA LMLEKVASSV 190 200 210 220 230 240 SIVHRRNAFR AHEHSVNNLE KSSIAIKTPF IPTEVLGNGD KLTHITLQEV KGDTTETLEI 250 260 270 280 290 300 DDFIINYGFV SSLGPIKNWG LELERNSIIV NSKMETNIPG IYCAGDICTY DGKVKLIATG 310 320 330 FGEAPTAVNN AMNFIDPKTR VQPMHSTSLF E

References

[1]

"Comparative genomics of Listeria species." Glaser P., Frangeul L., Buchrieser C., Rusniok C., Amend A., Baquero F., Berche P., Bloecker H., Brandt P., Chakraborty T., Charbit A., Chetouani F., Couve E., de Daruvar A., Dehoux P., Domann E., Dominguez-Bernal G., Duchaud E. , Durant L., Dussurget O., Entian K.-D., Fsihi H., Garcia-del Portillo F., Garrido P., Gautier L., Goebel W., Gomez-Lopez N., Hain T., Hauf J., Jackson D., Jones L.-M., Kaerst U., Kreft J., Kuhn M., Kunst F., Kurapkat G., Madueno E., Maitournam A., Mata Vicente J., Ng E., Nedjari H., Nordsiek G., Novella S., de Pablos B., Perez-Diaz J.-C., Purcell R., Remmel B., Rose M., Schlueter T., Simoes N., Tierrez A., Vazquez-Boland J.-A., Voss H., Wehland J., Cossart P. Science 294:849-852(2001) [PubMed: 11679669] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: CLIP 11262 / Serovar 6a.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AL596172 Genomic DNA. Translation: CAC97716.1.
PIR	AD1743.
RefSeq	NP_471819.1.
3D structure databases
HSSP	HSSP built from PDB template 1TRB based on UniProtKB P09625.
ModBase	Search...
Genome annotation databases
GeneID	1131289.
GenomeReviews	Gene locus lin2489 in contig AL592022_GR.
KEGG	lin:lin2489.
NMPDR	fig|272626.1.peg.2472.
Organism-specific databases
ListiList	LIN2489.
CMR	Search...
Phylogenomic databases
HOGENOM	Q928P3.
OMA	DWALMLE.
Enzyme and pathway databases
BioCyc	LINN272626:LIN2489-MON.
Family and domain databases
HAMAP	MF_01685. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR001327. Pyr_OxRdtase_NAD_bd. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
Pfam	PF00070. Pyr_redox. 1 hit. PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProDom	PD000139. FAD_pyr_redox. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

FENR2_LISIN

Accession

Primary (citable) accession number: Q928P3

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	December 1, 2001
Last modified:	November 3, 2009
This is version 51 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)