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Protein

Probable glutamate decarboxylase gamma

Gene

lin2528

Organism
Listeria innocua serovar 6a (strain CLIP 11262)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.

Cofactori

GO - Molecular functioni

  1. glutamate decarboxylase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. glutamate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Decarboxylase, Lyase

Keywords - Ligandi

Pyridoxal phosphate

Names & Taxonomyi

Protein namesi
Recommended name:
Probable glutamate decarboxylase gamma (EC:4.1.1.15)
Short name:
GAD-gamma
Gene namesi
Ordered Locus Names:lin2528
OrganismiListeria innocua serovar 6a (strain CLIP 11262)
Taxonomic identifieri272626 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria
ProteomesiUP000002513: Chromosome

Organism-specific databases

GenoListiLIN2528.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 467467Probable glutamate decarboxylase gammaPRO_0000146991Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei278 – 2781N6-(pyridoxal phosphate)lysineBy similarity

Interactioni

Protein-protein interaction databases

STRINGi272626.lin2528.

Structurei

3D structure databases

ProteinModelPortaliQ928K4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.Curated

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q928K4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLYSENDKRK HESYRIPLFG SEEESTSIPK YVLKKEPMEP RIAYQLVKDQ
60 70 80 90 100
LMDEGNARQN LATFCQTYME KEAEILMAET LEKNAIDKSE YPQTAELENR
110 120 130 140 150
CVNILADLWN APKEMSYLGT STVGSSEACM LGGLAMKFRW RNNAEKRGLD
160 170 180 190 200
IQAKRPNLII SSGYQVCWEK FCVYWDVDMR VVPMDKEHLS LDVEKVFELV
210 220 230 240 250
DEYTIGIVGI LGITYTGKFD DIALLDEKVE AYNEANEHQL VIHIDGASGA
260 270 280 290 300
MFTPFVNPEL PWDFRLKNVV SINTSGHKYG LVYPGVGWIL WKDKEYLPKE
310 320 330 340 350
LIFEVSYLGG SMPTMAINFS RSASQIIGQY YNFLRYGFEG YREIHEKTKK
360 370 380 390 400
TALYLSKTVE KSGYFEIIND GSNLPIVCYK LKDDLDVEWT LYDLADQLLM
410 420 430 440 450
KGWQVPAYPL PADLSDTIIQ RFVCRADLGY NVAEEFAADF ADALHNLEHA
460
RVLYHDKERN DSYGFTH
Length:467
Mass (Da):53,690
Last modified:December 1, 2001 - v1
Checksum:i008AB18F6E274590
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596172 Genomic DNA. Translation: CAC97755.1.
PIRiAC1748.
RefSeqiNP_471858.1. NC_003212.1.

Genome annotation databases

EnsemblBacteriaiCAC97755; CAC97755; CAC97755.
GeneIDi1131338.
KEGGilin:lin2528.
PATRICi20301953. VBILisInn102668_2590.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL596172 Genomic DNA. Translation: CAC97755.1.
PIRiAC1748.
RefSeqiNP_471858.1. NC_003212.1.

3D structure databases

ProteinModelPortaliQ928K4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi272626.lin2528.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAC97755; CAC97755; CAC97755.
GeneIDi1131338.
KEGGilin:lin2528.
PATRICi20301953. VBILisInn102668_2590.

Organism-specific databases

GenoListiLIN2528.

Phylogenomic databases

eggNOGiCOG0076.
HOGENOMiHOG000070228.
KOiK01580.
OMAiFVGTWMD.
OrthoDBiEOG6TFCPW.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: CLIP 11262.

Entry informationi

Entry nameiDCEC_LISIN
AccessioniPrimary (citable) accession number: Q928K4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2002
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.