Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q928I1 (TPIS1_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 62. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Triosephosphate isomerase 1
Short name=TIM 1
EC=5.3.1.1
Alternative name(s):
Triose-phosphate isomerase 1
Gene names
Name:tpiA1
Synonyms:tpi
Ordered Locus Names:lin2551
OrganismListeria innocua [Complete proteome] [HAMAP]
Taxonomic identifier1642 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length251 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP MF_00147_B

Pathway

Carbohydrate biosynthesis; gluconeogenesis. HAMAP MF_00147_B

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP MF_00147_B

Subunit structure

Homodimer By similarity. HAMAP MF_00147_B

Subcellular location

Cytoplasm By similarity HAMAP MF_00147_B.

Sequence similarities

Belongs to the triosephosphate isomerase family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
Pentose shunt
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-KW

glycolysis

Inferred from electronic annotation. Source: UniProtKB-KW

pentose-phosphate shunt

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiontriose-phosphate isomerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 251251Triosephosphate isomerase 1 HAMAP MF_00147_B
PRO_0000090238

Sites

Active site951Electrophile By similarity
Active site1671Proton acceptor By similarity
Binding site91Substrate By similarity
Binding site111Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q928I1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 6E9D1F2A0DEAF0DF

FASTA25126,861
        10         20         30         40         50         60 
MRKPIIAGNW KMNKTAAKAG QFAEDVKNNV PSSDAVESVV AAPALFLQEL VRLTEGTNLR 

        70         80         90        100        110        120 
VAAQNCYFED EGAFTGEISP FALADLGVSY VIIGHSERRE YFHETDEDIN KKAHAIFKHG 

       130        140        150        160        170        180 
MTPIICCGET LDQREAGQTD TWVRGQIRAA LAGLTEEQVI KSVIAYEPIW AIGTGKSSTS 

       190        200        210        220        230        240 
ADANETCAVI RAEVADAVSQ KAADAVRIQY GGSVKPENIA DYLAESDIDG ALVGGASLEP 

       250 
ASFLALLEAV K

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL596172 Genomic DNA. Translation: CAC97778.1.
PIRAB1751.
RefSeqNP_471881.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ928I1.
SMRQ928I1. Positions 2-249.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1131363.
GenomeReviewsGene locus lin2551 in contig AL592022_GR.
KEGGlin:lin2551.
PATRIC20301999. VBILisInn102668_2613.

Organism-specific databases

GenoListLIN2551.
CMRSearch...

Phylogenomic databases

HOGENOMHBG708281.
OMAVCVGETQ.
ProtClustDBPRK00042.

Enzyme and pathway databases

BioCycLINN272626:LIN2551-MONOMER.

Family and domain databases

HAMAPMF_00147_B. TIM_B.
[Tree]
InterProIPR013785. Aldolase_TIM.
IPR022896. TrioseP_Isoase_bac/euk.
IPR000652. Triosephosphate_isomerase.
IPR020861. Triosephosphate_isomerase_AS.
[Graphical view]
Gene3DG3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
KOK01803.
PANTHERPTHR21139. Triophos_ismrse. 1 hit.
PfamPF00121. TIM. 1 hit.
[Graphical view]
SUPFAMSSF51351. Triophos_ismrse. 1 hit.
TIGRFAMsTIGR00419. Tim. 1 hit.
PROSITEPS00171. TIM_1. 1 hit.
PS51440. TIM_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameTPIS1_LISIN
AccessionPrimary (citable) accession number: Q928I1
Entry history
Integrated into UniProtKB/Swiss-Prot: March 27, 2002
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 62 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents