SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q92804

- RBP56_HUMAN

UniProt

Q92804 - RBP56_HUMAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
TATA-binding protein-associated factor 2N
Gene
TAF15, RBP56, TAF2N
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).1 Publication

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri354 – 38532RanBP2-type
Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. nucleotide binding Source: InterPro
  3. poly(A) RNA binding Source: UniProtKB
  4. protein binding Source: UniProtKB
  5. zinc ion binding Source: InterPro
Complete GO annotation...

GO - Biological processi

  1. positive regulation of transcription, DNA-templated Source: UniProtKB
Complete GO annotation...

Keywords - Ligandi

DNA-binding, Metal-binding, RNA-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
TATA-binding protein-associated factor 2N
Alternative name(s):
68 kDa TATA-binding protein-associated factor
Short name:
TAF(II)68
Short name:
TAFII68
RNA-binding protein 56
Gene namesi
Name:TAF15
Synonyms:RBP56, TAF2N
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 17

Organism-specific databases

HGNCiHGNC:11547. TAF15.

Subcellular locationi

Nucleus. Cytoplasm
Note: Shuttles from the nucleus to the cytoplasm.1 Publication

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB
  2. nucleus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Nucleus

Pathology & Biotechi

Involvement in diseasei

A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.

Keywords - Diseasei

Proto-oncogene

Organism-specific databases

Orphaneti803. Amyotrophic lateral sclerosis.
209916. Extraskeletal myxoid chondrosarcoma.
PharmGKBiPA36322.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 592592TATA-binding protein-associated factor 2N
PRO_0000081749Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei206 – 2061Asymmetric dimethylarginine; by PRMT12 Publications
Modified residuei226 – 2261Phosphoserine1 Publication
Modified residuei231 – 2311Phosphoserine1 Publication
Modified residuei268 – 2681N6-acetyllysine1 Publication
Modified residuei423 – 4231Phosphoserine1 Publication
Modified residuei438 – 4381Phosphoserine1 Publication
Modified residuei442 – 4421Phosphoserine1 Publication
Modified residuei451 – 4511Phosphoserine1 Publication
Modified residuei483 – 4831Dimethylated arginine1 Publication
Modified residuei528 – 5281Asymmetric dimethylarginine; by PRMT11 Publication
Modified residuei535 – 5351Asymmetric dimethylarginine; by PRMT11 Publication
Modified residuei554 – 5541Phosphoserine1 Publication
Modified residuei570 – 5701Asymmetric dimethylarginine2 Publications
Modified residuei570 – 5701Asymmetric dimethylarginine; by PRMT12 Publications

Post-translational modificationi

Dimethylated by PRMT1 at Arg-206 to asymmetric dimethylarginine. The methylation may favor nuclear localization and positive regulation of TAF15 transcriptional activity.2 Publications
ADP-ribosylated during genotoxic stress.

Keywords - PTMi

Acetylation, ADP-ribosylation, Methylation, Phosphoprotein

Proteomic databases

MaxQBiQ92804.
PaxDbiQ92804.
PRIDEiQ92804.

PTM databases

PhosphoSiteiQ92804.

Miscellaneous databases

PMAP-CutDBQ92804.

Expressioni

Tissue specificityi

Ubiquitous. Observed in all fetal and adult tissues.

Gene expression databases

ArrayExpressiQ92804.
BgeeiQ92804.
CleanExiHS_TAF15.
GenevestigatoriQ92804.

Organism-specific databases

HPAiHPA052059.

Interactioni

Subunit structurei

Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1.

Binary interactionsi

WithEntry#Exp.IntActNotes
FUSP356375EBI-2255091,EBI-400434

Protein-protein interaction databases

BioGridi113807. 53 interactions.
DIPiDIP-52760N.
IntActiQ92804. 21 interactions.
MINTiMINT-3049394.
STRINGi9606.ENSP00000309558.

Structurei

3D structure databases

ProteinModelPortaliQ92804.
SMRiQ92804. Positions 232-319.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini234 – 32087RRM
Add
BLAST
Repeati407 – 41371
Repeati414 – 42072
Repeati421 – 42993
Repeati430 – 439104
Repeati440 – 44895
Repeati449 – 45796
Repeati458 – 46587
Repeati466 – 47388
Repeati474 – 48189
Repeati482 – 488710
Repeati489 – 496811
Repeati497 – 503712
Repeati504 – 510713
Repeati511 – 517714
Repeati518 – 524715
Repeati525 – 533916
Repeati534 – 5431017
Repeati544 – 551818
Repeati552 – 560919
Repeati561 – 568820
Repeati569 – 575721

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni407 – 57516921 X approximate tandem repeats of D-R-[S,G](0,3)-G-G-Y-G-G
Add
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi1 – 208208Gln/Gly/Ser/Tyr-rich
Add
BLAST
Compositional biasi320 – 590271Arg/Gly-rich
Add
BLAST

Sequence similaritiesi

Belongs to the RRM TET family.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG240581.
HOGENOMiHOG000038010.
HOVERGENiHBG005755.
InParanoidiQ92804.
KOiK14651.
OMAiQKQSSYS.
OrthoDBiEOG7DZ8N7.
PhylomeDBiQ92804.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
4.10.1060.10. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR001876. Znf_RanBP2.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
PF00641. zf-RanBP. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
SM00547. ZnF_RBZ. 1 hit.
[Graphical view]
PROSITEiPS50102. RRM. 1 hit.
PS01358. ZF_RANBP2_1. 1 hit.
PS50199. ZF_RANBP2_2. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform Long (identifier: Q92804-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MSDSGSYGQS GGEQQSYSTY GNPGSQGYGQ ASQSYSGYGQ TTDSSYGQNY    50
SGYSSYGQSQ SGYSQSYGGY ENQKQSSYSQ QPYNNQGQQQ NMESSGSQGG 100
RAPSYDQPDY GQQDSYDQQS GYDQHQGSYD EQSNYDQQHD SYSQNQQSYH 150
SQRENYSHHT QDDRRDVSRY GEDNRGYGGS QGGGRGRGGY DKDGRGPMTG 200
SSGGDRGGFK NFGGHRDYGP RTDADSESDN SDNNTIFVQG LGEGVSTDQV 250
GEFFKQIGII KTNKKTGKPM INLYTDKDTG KPKGEATVSF DDPPSAKAAI 300
DWFDGKEFHG NIIKVSFATR RPEFMRGGGS GGGRRGRGGY RGRGGFQGRG 350
GDPKSGDWVC PNPSCGNMNF ARRNSCNQCN EPRPEDSRPS GGDFRGRGYG 400
GERGYRGRGG RGGDRGGYGG DRSGGGYGGD RSSGGGYSGD RSGGGYGGDR 450
SGGGYGGDRG GGYGGDRGGG YGGDRGGGYG GDRGGYGGDR GGGYGGDRGG 500
YGGDRGGYGG DRGGYGGDRG GYGGDRSRGG YGGDRGGGSG YGGDRSGGYG 550
GDRSGGGYGG DRGGGYGGDR GGYGGKMGGR NDYRNDQRNR PY 592
Length:592
Mass (Da):61,830
Last modified:February 1, 1997 - v1
Checksum:i73D37C171E1E2BCA
GO
Isoform Short (identifier: Q92804-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     60-62: Missing.

Show »
Length:589
Mass (Da):61,558
Checksum:i5D24CA4BF574824A
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei60 – 623Missing in isoform Short.
VSP_005806

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U51334 mRNA. Translation: AAC50932.1.
X98893 mRNA. Translation: CAA67398.1.
AB010067 Genomic DNA. Translation: BAA33811.1.
AB010067 Genomic DNA. Translation: BAA33812.1.
AY197697 Genomic DNA. Translation: AAO13485.1.
AK313223 mRNA. Translation: BAG36034.1.
AK314194 mRNA. Translation: BAG36873.1.
AC015849 Genomic DNA. No translation available.
CH471147 Genomic DNA. Translation: EAW80124.1.
CH471147 Genomic DNA. Translation: EAW80125.1.
BC046099 mRNA. Translation: AAH46099.2.
CCDSiCCDS32623.1. [Q92804-1]
CCDS59279.1. [Q92804-2]
PIRiS71954.
RefSeqiNP_003478.1. NM_003487.3. [Q92804-2]
NP_631961.1. NM_139215.2. [Q92804-1]
UniGeneiHs.402752.

Genome annotation databases

EnsembliENST00000311979; ENSP00000309558; ENSG00000172660. [Q92804-2]
ENST00000588240; ENSP00000466950; ENSG00000172660. [Q92804-1]
ENST00000604841; ENSP00000474609; ENSG00000270647. [Q92804-2]
ENST00000605844; ENSP00000474096; ENSG00000270647. [Q92804-1]
GeneIDi8148.
KEGGihsa:8148.
UCSCiuc002hkc.4. human. [Q92804-2]
uc002hkd.4. human. [Q92804-1]

Polymorphism databases

DMDMi8928305.

Keywords - Coding sequence diversityi

Alternative splicing, Chromosomal rearrangement

Cross-referencesi

Web resourcesi

Atlas of Genetics and Cytogenetics in Oncology and Haematology
NIEHS-SNPs

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U51334 mRNA. Translation: AAC50932.1 .
X98893 mRNA. Translation: CAA67398.1 .
AB010067 Genomic DNA. Translation: BAA33811.1 .
AB010067 Genomic DNA. Translation: BAA33812.1 .
AY197697 Genomic DNA. Translation: AAO13485.1 .
AK313223 mRNA. Translation: BAG36034.1 .
AK314194 mRNA. Translation: BAG36873.1 .
AC015849 Genomic DNA. No translation available.
CH471147 Genomic DNA. Translation: EAW80124.1 .
CH471147 Genomic DNA. Translation: EAW80125.1 .
BC046099 mRNA. Translation: AAH46099.2 .
CCDSi CCDS32623.1. [Q92804-1 ]
CCDS59279.1. [Q92804-2 ]
PIRi S71954.
RefSeqi NP_003478.1. NM_003487.3. [Q92804-2 ]
NP_631961.1. NM_139215.2. [Q92804-1 ]
UniGenei Hs.402752.

3D structure databases

ProteinModelPortali Q92804.
SMRi Q92804. Positions 232-319.
ModBasei Search...

Protein-protein interaction databases

BioGridi 113807. 53 interactions.
DIPi DIP-52760N.
IntActi Q92804. 21 interactions.
MINTi MINT-3049394.
STRINGi 9606.ENSP00000309558.

PTM databases

PhosphoSitei Q92804.

Polymorphism databases

DMDMi 8928305.

Proteomic databases

MaxQBi Q92804.
PaxDbi Q92804.
PRIDEi Q92804.

Protocols and materials databases

DNASUi 8148.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000311979 ; ENSP00000309558 ; ENSG00000172660 . [Q92804-2 ]
ENST00000588240 ; ENSP00000466950 ; ENSG00000172660 . [Q92804-1 ]
ENST00000604841 ; ENSP00000474609 ; ENSG00000270647 . [Q92804-2 ]
ENST00000605844 ; ENSP00000474096 ; ENSG00000270647 . [Q92804-1 ]
GeneIDi 8148.
KEGGi hsa:8148.
UCSCi uc002hkc.4. human. [Q92804-2 ]
uc002hkd.4. human. [Q92804-1 ]

Organism-specific databases

CTDi 8148.
GeneCardsi GC17P034136.
HGNCi HGNC:11547. TAF15.
HPAi HPA052059.
MIMi 601574. gene.
neXtProti NX_Q92804.
Orphaneti 803. Amyotrophic lateral sclerosis.
209916. Extraskeletal myxoid chondrosarcoma.
PharmGKBi PA36322.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG240581.
HOGENOMi HOG000038010.
HOVERGENi HBG005755.
InParanoidi Q92804.
KOi K14651.
OMAi QKQSSYS.
OrthoDBi EOG7DZ8N7.
PhylomeDBi Q92804.

Miscellaneous databases

ChiTaRSi TAF15. human.
GeneWikii TAF15.
GenomeRNAii 8148.
NextBioi 30819.
PMAP-CutDB Q92804.
PROi Q92804.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q92804.
Bgeei Q92804.
CleanExi HS_TAF15.
Genevestigatori Q92804.

Family and domain databases

Gene3Di 3.30.70.330. 1 hit.
4.10.1060.10. 1 hit.
InterProi IPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
IPR001876. Znf_RanBP2.
[Graphical view ]
Pfami PF00076. RRM_1. 1 hit.
PF00641. zf-RanBP. 1 hit.
[Graphical view ]
SMARTi SM00360. RRM. 1 hit.
SM00547. ZnF_RBZ. 1 hit.
[Graphical view ]
PROSITEi PS50102. RRM. 1 hit.
PS01358. ZF_RANBP2_1. 1 hit.
PS50199. ZF_RANBP2_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and mapping of a human RBP56 gene encoding a putative RNA binding protein similar to FUS/TLS and EWS proteins."
    Morohoshi F., Arai K., Takahashi E., Tanigami A., Ohki M.
    Genomics 38:51-57(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS LONG AND SHORT).
  2. "hTAF(II)68, a novel RNA/ssDNA-binding protein with homology to the pro-oncoproteins TLS/FUS and EWS is associated with both TFIID and RNA polymerase II."
    Bertolotti A., Lutz Y., Heard D.J., Chambon P., Tora L.
    EMBO J. 15:5022-5031(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM SHORT), PROTEIN SEQUENCE OF 282-297 AND 307-320.
  3. "Genomic structure of the human RBP56/hTAFII68 and FUS/TLS genes."
    Morohoshi F., Ootsuka Y., Arai K., Ichikawa H., Mitani S., Munakata N., Ohki M.
    Gene 221:191-198(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS LONG AND SHORT).
  4. NIEHS SNPs program
    Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS SHORT AND LONG).
    Tissue: Tongue.
  6. "DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage."
    Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L.
    , Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.
    Nature 440:1045-1049(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM LONG).
    Tissue: Testis.
  9. Bienvenut W.V., Lilla S., von Kriegsheim A., Lempens A., Kolch W.
    Submitted (DEC-2008) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 75-101; 196-210; 284-306; 476-490 AND 563-576, METHYLATION AT ARG-206; ARG-483 AND ARG-570, IDENTIFICATION BY MASS SPECTROMETRY.
    Tissue: Ovarian carcinoma.
  10. "The transcriptional repressor ZFM1 interacts with and modulates the ability of EWS to activate transcription."
    Zhang D., Paley A.J., Childs G.
    J. Biol. Chem. 273:18086-18091(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: INTERACTION WITH SF1.
  11. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic kidney.
  12. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.
  13. "PRMT1 mediated methylation of TAF15 is required for its positive gene regulatory function."
    Jobert L., Argentini M., Tora L.
    Exp. Cell Res. 315:1273-1286(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, METHYLATION AT ARG-206; ARG-528; ARG-535 AND ARG-570 BY PRMT1, IDENTIFICATION BY MASS SPECTROMETRY, SUBCELLULAR LOCATION.
  14. "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
    Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K., Rodionov V., Han D.K.
    Sci. Signal. 2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-226 AND SER-231, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Leukemic T-cell.
  15. "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
    Choudhary C., Kumar C., Gnad F., Nielsen M.L., Rehman M., Walther T.C., Olsen J.V., Mann M.
    Science 325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-268, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  16. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  17. "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
    Rigbolt K.T., Prokhorova T.A., Akimov V., Henningsen J., Johansen P.T., Kratchmarova I., Kassem M., Mann M., Olsen J.V., Blagoev B.
    Sci. Signal. 4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
    Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-423; SER-438; SER-442; SER-451 AND SER-554, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
  18. "Proteome-wide identification of poly(ADP-Ribosyl)ation targets in different genotoxic stress responses."
    Jungmichel S., Rosenthal F., Altmeyer M., Lukas J., Hottiger M.O., Nielsen M.L.
    Mol. Cell 52:272-285(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: ADP-RIBOSYLATION.

Entry informationi

Entry nameiRBP56_HUMAN
AccessioniPrimary (citable) accession number: Q92804
Secondary accession number(s): B2R837, Q86X94, Q92751
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: February 1, 1997
Last modified: September 3, 2014
This is version 154 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. Human chromosome 17
    Human chromosome 17: entries, gene names and cross-references to MIM
  2. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi