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Q927W2 (ATPA2_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
ATP synthase subunit alpha 2
EC=3.6.3.14
Alternative name(s):
ATP synthase F1 sector subunit alpha 2
F-ATPase subunit alpha 2
Gene names
Name:atpA2
Ordered Locus Names:lin2675
OrganismListeria innocua [Complete proteome] [HAMAP]
Taxonomic identifier1642 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Listeriaceae › Listeria

Protein attributes

Sequence length504 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit By similarity. HAMAP MF_01346

Catalytic activity

ATP + H2O + H+(In) = ADP + phosphate + H+(Out). HAMAP MF_01346

Subunit structure

F-type ATPases have 2 components, CF1 - the catalytic core - and CF0 - the membrane proton channel. CF1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. CF0 has three main subunits: a1, b2 and c(9-12). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. CF1 is attached to CF0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains By similarity.

Subcellular location

Cell membrane; Peripheral membrane protein By similarity HAMAP MF_01346.

Sequence similarities

Belongs to the ATPase alpha/beta chains family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 504504ATP synthase subunit alpha 2 HAMAP MF_01346
PRO_0000238278

Regions

Nucleotide binding169 – 1768ATP By similarity

Sites

Site3621Required for activity By similarity

Sequences

Sequence LengthMass (Da)Tools
Q927W2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 65689D02CA8D65F3

FASTA50455,051
        10         20         30         40         50         60 
MSIKAEEISS IIKQQIENYQ SELKVSDVGT VTYIGDGIAR AHGLDNAMAG ELLEFSNGVM 

        70         80         90        100        110        120 
GMAQNLETND VGIIILGPYT EIREGDEVRR TGKIMEVPVG EALIGRVVNS LGQPVDGLGP 

       130        140        150        160        170        180 
IETTGTRPIE AVAPGVMQRQ SVNEPLQTGI KAIDALVPIG RGQRELIIGD RQTGKTSVAI 

       190        200        210        220        230        240 
DTILNQADQD MICIYVAIGQ KESTVRNAVE TLRHHGALDY TIVVTAAASQ PAPLLYLAPY 

       250        260        270        280        290        300 
AGVAMAEEFM YSGKHVLVVY DDLSKQAAAY RELSLLLRRP PGREAYPGDV FYLHSRLLER 

       310        320        330        340        350        360 
AAKLNDSLGG GSITALPFVE TQAGDISAYI PTNVISITDG QIFLQSDLFF SGVRPAINAG 

       370        380        390        400        410        420 
LSVSRVGGSA QIKAMKTVAG TLRLDLAAYR ELESFSQFGS DLDAATRAKL ERGKRTVEVL 

       430        440        450        460        470        480 
KQDLHKPLKV EKQVLILYAL VHKYLDDVPV HDVLRFESEM NTWFDHNHPE LLEEIRTTKK 

       490        500 
LPDEAKLEAA LKEFKNTFVP SEEK

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AL596173 Genomic DNA. Translation: CAC97901.1.
PIRAE1766.
RefSeqNP_472004.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ927W2.
SMRQ927W2. Positions 21-502.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1131515.
GenomeReviewsGene locus lin2675 in contig AL592022_GR.
KEGGlin:lin2675.
NMPDRfig|272626.1.peg.2657.
PATRIC20302265. VBILisInn102668_2745.

Organism-specific databases

GenoListLIN2675.
CMRSearch...

Phylogenomic databases

HOGENOMHBG565875.
OMAFRVGIKA.
ProtClustDBPRK09281.

Enzyme and pathway databases

BioCycLINN272626:LIN2675-MONOMER.

Family and domain databases

HAMAPMF_01346. ATP_synth_alpha_bact.
[Tree]
InterProIPR020003. ATPase_a/bsu_AS.
IPR005294. ATPase_F1-cplx_asu.
IPR018118. ATPase_F1/A1-cplx_a/bsu_N.
IPR023366. ATPase_F1/A1-cplx_a_su_N.
IPR000793. ATPase_F1/V1/A1-cplx_a/bsu_C.
IPR004100. ATPase_F1/V1/A1-cplx_a/bsu_N.
IPR000194. ATPase_F1/V1/A1_a/bsu_nucl-bd.
[Graphical view]
Gene3DG3DSA:2.40.30.20. G3DSA:2.40.30.20. 1 hit.
KOK02111.
PANTHERPTHR15184:SF3. ATPase_F1_a. 1 hit.
PfamPF00006. ATP-synt_ab. 1 hit.
PF00306. ATP-synt_ab_C. 1 hit.
PF02874. ATP-synt_ab_N. 1 hit.
[Graphical view]
SUPFAMSSF47917. ATPase_a/b_C. 1 hit.
SSF50615. ATPase_a/b_N. 1 hit.
TIGRFAMsTIGR00962. AtpA. 1 hit.
PROSITEPS00152. ATPASE_ALPHA_BETA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameATPA2_LISIN
AccessionPrimary (citable) accession number: Q927W2
Entry history
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: December 1, 2001
Last modified: January 25, 2012
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

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