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Q927T2 (SYR_LISIN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:lin2706
OrganismListeria innocua serovar 6a (strain CLIP 11262) [Complete proteome] [HAMAP]
Taxonomic identifier272626 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesListeriaceaeListeria

Protein attributes

Sequence length556 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 556556Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000151572

Regions

Motif132 – 14211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q927T2 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 54CCEF31E6567056

FASTA55662,784
        10         20         30         40         50         60 
MNVMQENQIK LIEHIKQAVV QAVGLEETEV PEILLEVPKD KKHGDYSTNI AMQLARVAKK 

        70         80         90        100        110        120 
APRQIAESIV PELKKDTKLI KEVEIAGPGF INFYLDNAYL TDLVPVILTE DKKYGESDFG 

       130        140        150        160        170        180 
KGEKFQIEFV SANPTGDLHL GHARGAAIGD SLANIMKMAG FDVSREYYIN DAGNQINNLV 

       190        200        210        220        230        240 
LSAEARYFEA LGLESEFPED GYRGSDIIAL GKDLAAKYGD KYVNASEEER RSVFRVDALA 

       250        260        270        280        290        300 
FETGKLRADL EEFRVSFDEW FSETSLYEEN KVLPALERLR ENGYIYEQDG ATWLRTTDFE 

       310        320        330        340        350        360 
DDKDRVLIKS DGSYTYFLPD IAYHLNKLER GFDVLIDIWG ADHHGYIPRM RAAIEALGYS 

       370        380        390        400        410        420 
PNQLEVEIIQ LVHLFEDGVQ VKMSKRTGKS VTMRDLIEEV GLDATRYFFA MRSSDTHMNF 

       430        440        450        460        470        480 
DMSLAKSTSN DNPVYYVQYA HARISSILRS GKEQGLEVSK DANMSLLETE AEYDLLKVLG 

       490        500        510        520        530        540 
EFADVVAEAA VKRAPHRIVR YLNDLATAFH RFYNSNKVLD MDNLEVTKAR LALIKTAQIT 

       550 
LRNGLTLLGV SAPEKM 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AL596173 Genomic DNA. Translation: CAC97932.1.
PIRAD1770.
RefSeqNP_472035.1. NC_003212.1.

3D structure databases

ProteinModelPortalQ927T2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING272626.lin2706.

Protocols and materials databases

DNASU1131552.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAC97932; CAC97932; CAC97932.
GeneID1131552.
KEGGlin:lin2706.
PATRIC20302331. VBILisInn102668_2778.

Organism-specific databases

GenoListLIN2706.
CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247214.
KOK01887.
OMAMEHMGFG.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_LISIN
AccessionPrimary (citable) accession number: Q927T2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 20, 2002
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries