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Protein

Putative zinc finger protein 75C

Gene

ZNF75CP

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein uncertaini

Functioni

May be involved in transcriptional regulation.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri292 – 31423C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri320 – 34223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri348 – 37023C2H2-type 3; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri376 – 39823C2H2-type 4; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri404 – 42623C2H2-type 5PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative zinc finger protein 75C
Alternative name(s):
Zinc finger protein 75C pseudogene
Gene namesi
Name:ZNF75CP
Synonyms:ZNF75C
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Unplaced

Organism-specific databases

HGNCiHGNC:13148. ZNF75CP.

Subcellular locationi

  • Nucleus PROSITE-ProRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Polymorphism and mutation databases

DMDMi205831223.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 426426Putative zinc finger protein 75CPRO_0000349242Add
BLAST

Proteomic databases

PRIDEiQ92670.

PTM databases

iPTMnetiQ92670.
PhosphoSiteiQ92670.

Structurei

3D structure databases

ProteinModelPortaliQ92670.
SMRiQ92670. Positions 45-133, 257-426.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 13183SCAN boxPROSITE-ProRule annotationAdd
BLAST
Domaini205 – 28985KRABPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 5 C2H2-type zinc fingers.PROSITE-ProRule annotation
Contains 1 KRAB domain.PROSITE-ProRule annotation
Contains 1 SCAN box domain.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri292 – 31423C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri320 – 34223C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri348 – 37023C2H2-type 3; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri376 – 39823C2H2-type 4; degeneratePROSITE-ProRule annotationAdd
BLAST
Zinc fingeri404 – 42623C2H2-type 5PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

HOVERGENiHBG018163.
InParanoidiQ92670.
PhylomeDBiQ92670.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR001909. KRAB.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92670-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIMRELKADA CLNSHMGAMW ETNRSVKENS SQSKKYSTQI ECLSPGSACR
60 70 80 90 100
HFRSFHYHEA TEPLEAINQL QKLCHQWLRP EIHSKKHILE MLVLEHFLTI
110 120 130 140 150
LPKGTQNWVQ KHHPQLAKQA LVLVERLQRE PGGTKNEVTA HELGEEAVLL
160 170 180 190 200
RGTTVAPGFK WKPAELEPME RILEHIQILA LSEHKSTKDW KMAPKLIWPE
210 220 230 240 250
SQSLLTFEDM AVYFSEEEWQ LLGPLEKTLY NDVMQDIYET AISLGKQRTG
260 270 280 290 300
KIMGIEMASS FSKEEKKLTT CKQELPKLMD LHGKGHTGEK PFKCQDCGKI
310 320 330 340 350
FRVSSDLIKH QRIHTEEKLY KCQQCDRRFR WSSGLNKHFM THQGINPYRC
360 370 380 390 400
SWYGKSISYD TNLQTHQRIH TGEKPFKCHE CGKIFIHKSN LIKYQRTHTG
410 420
EQPYTCSICR RNFSRQLSLL RHQKLH
Length:426
Mass (Da):49,753
Last modified:September 2, 2008 - v2
Checksum:iF88B9E97A42FA06B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti394 – 3941Y → H in CAA62937 (PubMed:8661144).Curated
Sequence conflicti408 – 4103ICR → LCK in CAA62937 (PubMed:8661144).Curated
Sequence conflicti416 – 4172QL → RS in CAA62937 (PubMed:8661144).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003086 Genomic DNA. No translation available.
X91828 Genomic DNA. Translation: CAA62937.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP003086 Genomic DNA. No translation available.
X91828 Genomic DNA. Translation: CAA62937.1.

3D structure databases

ProteinModelPortaliQ92670.
SMRiQ92670. Positions 45-133, 257-426.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiQ92670.
PhosphoSiteiQ92670.

Polymorphism and mutation databases

DMDMi205831223.

Proteomic databases

PRIDEiQ92670.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

GeneCardsiZNF75CP.
HGNCiHGNC:13148. ZNF75CP.
neXtProtiNX_Q92670.
GenAtlasiSearch...

Phylogenomic databases

HOVERGENiHBG018163.
InParanoidiQ92670.
PhylomeDBiQ92670.

Enzyme and pathway databases

ReactomeiR-HSA-212436. Generic Transcription Pathway.

Family and domain databases

Gene3Di3.30.160.60. 5 hits.
InterProiIPR001909. KRAB.
IPR008916. Retrov_capsid_C.
IPR003309. SCAN_dom.
IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF01352. KRAB. 1 hit.
PF02023. SCAN. 1 hit.
PF00096. zf-C2H2. 1 hit.
[Graphical view]
SMARTiSM00349. KRAB. 1 hit.
SM00431. SCAN. 1 hit.
SM00355. ZnF_C2H2. 5 hits.
[Graphical view]
SUPFAMiSSF109640. SSF109640. 1 hit.
SSF47353. SSF47353. 1 hit.
PROSITEiPS50805. KRAB. 1 hit.
PS50804. SCAN_BOX. 1 hit.
PS00028. ZINC_FINGER_C2H2_1. 3 hits.
PS50157. ZINC_FINGER_C2H2_2. 5 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  2. "The ZNF75 zinc finger gene subfamily: isolation and mapping of the four members in humans and great apes."
    Villa A., Strina D., Frattini A., Faranda S., Macchi P., Finelli P., Bozzi F., Susani L., Archidiacono N., Rocchi M., Vezzoni P.
    Genomics 35:312-320(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 333-422.
    Tissue: Peripheral blood.

Entry informationi

Entry nameiZN75C_HUMAN
AccessioniPrimary (citable) accession number: Q92670
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 8, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Caution

Could be the product of a pseudogene.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.