Select a section on the left to see content.
<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni
Interacts with the internal control region (ICR) of approximately 50 bases within the 5S RNA genes, is required for correct transcription of these genes by RNA polymerase III. Also binds the transcribed 5S RNA's. May initiate transcription of the 5S ribosomal RNA gene and maintain the stability of transcription of other genes.
Regions
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
- DNA binding
- metal ion binding
- RNA binding
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi
- gene expression
- regulation of transcription, DNA-templated
- rRNA transcription
<p>Traceable Author Statement</p>
<p>Used for information from review articles where the original experiments are traceable through that article and also for information from text books or dictionaries.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#tas">GO evidence code guide</a></p> Traceable author statementi
- transcription from RNA polymerase III promoter
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Biological processi
Transcription, Transcription regulation
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Ligandi
DNA-binding, Metal-binding, RNA-binding, ZincEnzyme and pathway databases
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Reactome - a knowledgebase of biological pathways and processes<br/><a href='/database/88'>More..</a>Reactomei | REACT_22339. RNA Polymerase III Abortive And Retractive Initiation.
REACT_347. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
|
<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi
| <p>Provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.</p><p><a href='../manual/protein_names' target='_top'>More...</a></p>Protein namesi | Recommended name: Transcription factor IIIAShort name: TFIIIA |
| <p>Indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. 4 distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.</p><p><a href='../manual/gene_name' target='_top'>More...</a></p>Gene namesi | |
| <p>Provides information on the name(s) of the organism that is the source of the protein sequence.</p><p><a href='../manual/organism-name' target='_top'>More...</a></p>Organismi | Homo sapiens (Human) |
| <p>Shows the unique identifier assigned by the <span class="caps">NCBI</span> to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.</p><p><a href='../manual/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri | 9606 [NCBI] |
| <p>Contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.</p><p><a href='../manual/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineagei | cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo |
| <p>Is present for entries that are part of a <a href="/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.</p><p><a href='../manual/proteomes_manual' target='_top'>More...</a></p>Proteomesi | UP000005640: Chromosome 13 |
Organism-specific databases
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Human Gene Nomenclature Database<br/><a href='/database/42'>More..</a>HGNCi | HGNC:4662. GTF3A.
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<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti
- nucleoplasm
- nucleus
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti
Nucleus<p>Provides information on the disease(s) and phenotype(s) associated with the deficiency of a protein.</p><p><a href='../manual/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi
Organism-specific databases
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The Pharmacogenetics and Pharmacogenomics Knowledge Base<br/><a href='/database/74'>More..</a>PharmGKBi | PA29048.
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<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi
Molecule processing
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the extent of a polypeptide chain in the mature protein following processing.</p><p><a href='../manual/chain' target='_top'>More...</a></p>Chaini | 1 – 365 | 365 | Transcription factor IIIA |  | PRO_0000047080 | Add
BLAST |
Proteomic databases
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MaxQB - The MaxQuant DataBase<br/><a href='/database/186'>More..</a>MaxQBi | Q92664.
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PaxDb, a database of protein abundance averages across all three domains of life.<br/><a href='/database/173'>More..</a>PaxDbi | Q92664.
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PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | Q92664.
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PTM databases
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Phosphorylation site database<br/><a href='/database/123'>More..</a>PhosphoSitei | Q92664.
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<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni
<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at the protein level’.</p><p><a href='../manual/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi
Ubiquitous.
Gene expression databases
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Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | Q92664.
|
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CleanEx database of gene expression profiles<br/><a href='/database/8'>More..</a>CleanExi | HS_GTF3A.
|
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ExpressionAtlas, Differential and Baseline Expression<br/><a href='/database/4'>More..</a>ExpressionAtlasi | Q92664. baseline and differential.
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Genevestigator<br/><a href='/database/142'>More..</a>Genevestigatori | Q92664.
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Organism-specific databases
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Human Protein Atlas<br/><a href='/database/46'>More..</a>HPAi | HPA007990.
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<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni
Protein-protein interaction databases
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The Biological General Repository for Interaction Datasets (BioGrid)<br/><a href='/database/184'>More..</a>BioGridi | 109226. 5 interactions.
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Protein interaction database and analysis system<br/><a href='/database/51'>More..</a>IntActi | Q92664. 6 interactions.
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STRING: functional protein association networks<br/><a href='/database/141'>More..</a>STRINGi | 9606.ENSP00000370532.
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<p>Provides information on the tertiary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei
3D structure databases
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Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase<br/><a href='/database/159'>More..</a>ProteinModelPortali | Q92664.
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SWISS-MODEL Repository - a database of annotated 3D protein structure models<br/><a href='/database/98'>More..</a>SMRi | Q92664. Positions 38-339.
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Database of comparative protein structure models<br/><a href='/database/63'>More..</a>ModBasei | Search...
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MobiDB: a database of protein disorder and mobility annotations<br/><a href='/database/183'>More..</a>MobiDBi | Search...
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<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi
<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi
Contains 9
C2H2-type zinc fingers.
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
Zinc finger
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Domaini
Repeat, Zinc-fingerPhylogenomic databases
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evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | COG5048.
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The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000232112.
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The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG017915.
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InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | Q92664.
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KEGG Orthology (KO)<br/><a href='/database/164'>More..</a>KOi | K09191.
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Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | Q92664.
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TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF333011.
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Family and domain databases
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Gene3D Structural and Functional Annotation of Protein Families<br/><a href='/database/29'>More..</a>Gene3Di | 3.30.160.60. 8 hits.
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Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view] |
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Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF00096. zf-C2H2. 4 hits.
[Graphical view] |
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Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00355. ZnF_C2H2. 9 hits.
[Graphical view] |
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PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 8 hits.
[Graphical view] |
<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequences (2)i
<p>Indicates if the canonical sequence displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.
This entry describes 2<p>Lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.</p><p><a href='../manual/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. Align
<p>Reports difference(s) between the protein sequence shown in the UniProtKB entry and other available protein sequences derived from the same gene.</p><p><a href='../manual/sequence_caution' target='_top'>More...</a></p>Sequence cautioni
The sequence
BAA06988.1 differs from that shown. Reason: Erroneous initiation.
Translation N-terminally shortened.Experimental Info
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.</p><p><a href='../manual/conflict' target='_top'>More...</a></p>Sequence conflicti | 156 – 156 | 1 | H → N in BAA06988. (PubMed:7789179) |  | | |
| <p>Reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.</p><p><a href='../manual/conflict' target='_top'>More...</a></p>Sequence conflicti | 319 – 319 | 1 | R → G in BAA06988. (PubMed:7789179) | | | |
Natural variant
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes natural variant(s) of the protein sequence.</p><p><a href='../manual/variant' target='_top'>More...</a></p>Natural varianti | 245 – 245 | 1 | V → L.
Corresponds to variant rs7323 [ dbSNP | Ensembl ]. | | VAR_014824 | |
Alternative sequence
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.</p><p><a href='../manual/var_seq' target='_top'>More...</a></p>Alternative sequencei | 164 – 188 | 25 | Missing in isoform 2.
<p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p>
<p><a href="/manual/evidences#ECO:0000303">More…</a></p> Manual assertion based on opinion ini Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-365 (ISOFORMS 1 AND 2).
| | VSP_031525 | Add
BLAST |
| <p>Describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.</p><p><a href='../manual/var_seq' target='_top'>More...</a></p>Alternative sequencei | 189 – 190 | 2 | YV → LC in isoform 2.
<p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p>
<p><a href="/manual/evidences#ECO:0000303">More…</a></p> Manual assertion based on opinion ini Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 2-365 (ISOFORMS 1 AND 2).
| | VSP_031526 | |
Sequence databases
Genome annotation databases
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Ensembl eukaryotic genome annotation project<br/><a href='/database/23'>More..</a>Ensembli | ENST00000381140; ENSP00000370532; ENSG00000122034.
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Database of genes from NCBI RefSeq genomes<br/><a href='/database/118'>More..</a>GeneIDi | 2971.
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KEGG: Kyoto Encyclopedia of Genes and Genomes<br/><a href='/database/53'>More..</a>KEGGi | hsa:2971.
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UCSC genome browser<br/><a href='/database/139'>More..</a>UCSCi | uc001ure.2. human. [Q92664-1]
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Polymorphism databases
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Domain mapping of disease mutations (DMDM)<br/><a href='/database/166'>More..</a>DMDMi | 172045838.
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<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi
Alternative splicing, Polymorphism<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi
Sequence databases
3D structure databases
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Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase<br/><a href='/database/159'>More..</a>ProteinModelPortali | Q92664.
|
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SWISS-MODEL Repository - a database of annotated 3D protein structure models<br/><a href='/database/98'>More..</a>SMRi | Q92664. Positions 38-339.
|
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Database of comparative protein structure models<br/><a href='/database/63'>More..</a>ModBasei | Search...
|
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MobiDB: a database of protein disorder and mobility annotations<br/><a href='/database/183'>More..</a>MobiDBi | Search...
|
Protein-protein interaction databases
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The Biological General Repository for Interaction Datasets (BioGrid)<br/><a href='/database/184'>More..</a>BioGridi | 109226. 5 interactions.
|
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Protein interaction database and analysis system<br/><a href='/database/51'>More..</a>IntActi | Q92664. 6 interactions.
|
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STRING: functional protein association networks<br/><a href='/database/141'>More..</a>STRINGi | 9606.ENSP00000370532.
|
PTM databases
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Phosphorylation site database<br/><a href='/database/123'>More..</a>PhosphoSitei | Q92664.
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Polymorphism databases
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Domain mapping of disease mutations (DMDM)<br/><a href='/database/166'>More..</a>DMDMi | 172045838.
|
Proteomic databases
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MaxQB - The MaxQuant DataBase<br/><a href='/database/186'>More..</a>MaxQBi | Q92664.
|
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PaxDb, a database of protein abundance averages across all three domains of life.<br/><a href='/database/173'>More..</a>PaxDbi | Q92664.
|
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PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | Q92664.
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Protocols and materials databases
Genome annotation databases
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Ensembl eukaryotic genome annotation project<br/><a href='/database/23'>More..</a>Ensembli | ENST00000381140; ENSP00000370532; ENSG00000122034.
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Database of genes from NCBI RefSeq genomes<br/><a href='/database/118'>More..</a>GeneIDi | 2971.
|
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KEGG: Kyoto Encyclopedia of Genes and Genomes<br/><a href='/database/53'>More..</a>KEGGi | hsa:2971.
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UCSC genome browser<br/><a href='/database/139'>More..</a>UCSCi | uc001ure.2. human. [Q92664-1]
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Organism-specific databases
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Comparative Toxicogenomics Database<br/><a href='/database/140'>More..</a>CTDi | 2971.
|
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GeneCards: human genes, protein and diseases<br/><a href='/database/30'>More..</a>GeneCardsi | GC13P027998.
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H-InvDB | HIX0011192.
HIX0130586.
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Human Gene Nomenclature Database<br/><a href='/database/42'>More..</a>HGNCi | HGNC:4662. GTF3A.
|
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Human Protein Atlas<br/><a href='/database/46'>More..</a>HPAi | HPA007990.
|
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Online Mendelian Inheritance in Man (OMIM)<br/><a href='/database/62'>More..</a>MIMi | 600860. gene.
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neXtProt; the human protein knowledge platform<br/><a href='/database/161'>More..</a>neXtProti | NX_Q92664.
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The Pharmacogenetics and Pharmacogenomics Knowledge Base<br/><a href='/database/74'>More..</a>PharmGKBi | PA29048.
|
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GenAtlas: human gene database<br/><a href='/database/27'>More..</a>GenAtlasi | Search...
|
Phylogenomic databases
|
evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | COG5048.
|
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The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000232112.
|
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The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG017915.
|
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InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | Q92664.
|
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KEGG Orthology (KO)<br/><a href='/database/164'>More..</a>KOi | K09191.
|
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Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | Q92664.
|
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TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF333011.
|
Enzyme and pathway databases
|
Reactome - a knowledgebase of biological pathways and processes<br/><a href='/database/88'>More..</a>Reactomei | REACT_22339. RNA Polymerase III Abortive And Retractive Initiation.
REACT_347. RNA Polymerase III Transcription Initiation From Type 1 Promoter.
|
Miscellaneous databases
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ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data.<br/><a href='/database/176'>More..</a>ChiTaRSi | GTF3A. human.
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GeneWiki<br/><a href='/database/180'>More..</a>GeneWikii | GTF3A.
|
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Database of phenotypes from RNA interference screens in Drosophila and Homo sapiens.<br/><a href='/database/169'>More..</a>GenomeRNAii | 2971.
|
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NextBio gene-centric data for human, mouse, rat, fly, worm and yeast<br/><a href='/database/128'>More..</a>NextBioi | 11783.
|
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Protein Ontology<br/><a href='/database/181'>More..</a>PROi | Q92664.
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The Stanford Online Universal Resource for Clones and ESTs<br/><a href='/database/99'>More..</a>SOURCEi | Search...
|
Gene expression databases
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Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | Q92664.
|
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CleanEx database of gene expression profiles<br/><a href='/database/8'>More..</a>CleanExi | HS_GTF3A.
|
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ExpressionAtlas, Differential and Baseline Expression<br/><a href='/database/4'>More..</a>ExpressionAtlasi | Q92664. baseline and differential.
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Genevestigator<br/><a href='/database/142'>More..</a>Genevestigatori | Q92664.
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Family and domain databases
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Gene3D Structural and Functional Annotation of Protein Families<br/><a href='/database/29'>More..</a>Gene3Di | 3.30.160.60. 8 hits.
|
|
Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view] |
|
Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF00096. zf-C2H2. 4 hits.
[Graphical view] |
|
Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00355. ZnF_C2H2. 9 hits.
[Graphical view] |
|
PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS00028. ZINC_FINGER_C2H2_1. 8 hits.
PS50157. ZINC_FINGER_C2H2_2. 8 hits.
[Graphical view] |
|
ProtoNet; Automatic hierarchical classification of proteins<br/><a href='/database/85'>More..</a>ProtoNeti | Search...
|
<p>Contains the literature citations that are the sources of data used to annotate the entry. Each reference is numbered and contains several subsections allowing a precise description of a given citation.</p><p><a href='../manual/publications_section' target='_top'>More...</a></p>Publicationsi
"Molecular cloning, characterization, and chromosomal mapping of a novel human gene (GTF3A) that is highly homologous to Xenopus transcription factor IIIA."Arakawa H.,
Nagase H.,
Hayashi N.,
Ogawa M.,
Nagata M.,
Fujiwara T.,
Takahashi E.,
Shin S.,
Nakamura Y.Cytogenet. Cell Genet. 70:235-238(1995) [
PubMed] [
Europe PMC] [
Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
Tissue: Fetal brain.
"The DNA sequence and analysis of human chromosome 13."Dunham A.,
Matthews L.H.,
Burton J.,
Ashurst J.L.,
Howe K.L.,
Ashcroft K.J.,
Beare D.M.,
Burford D.C.,
Hunt S.E.,
Griffiths-Jones S.,
Jones M.C.,
Keenan S.J.,
Oliver K.,
Scott C.E.,
Ainscough R.,
Almeida J.P.,
Ambrose K.D.,
Andrews D.T. , Ashwell R.I.S., Babbage A.K., Bagguley C.L., Bailey J., Bannerjee R., Barlow K.F., Bates K., Beasley H., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burrill W., Carder C., Carter N.P., Chapman J.C., Clamp M.E., Clark S.Y., Clarke G., Clee C.M., Clegg S.C., Cobley V., Collins J.E., Corby N., Coville G.J., Deloukas P., Dhami P., Dunham I., Dunn M., Earthrowl M.E., Ellington A.G., Faulkner L., Frankish A.G., Frankland J., French L., Garner P., Garnett J., Gilbert J.G.R., Gilson C.J., Ghori J., Grafham D.V., Gribble S.M., Griffiths C., Hall R.E., Hammond S., Harley J.L., Hart E.A., Heath P.D., Howden P.J., Huckle E.J., Hunt P.J., Hunt A.R., Johnson C., Johnson D., Kay M., Kimberley A.M., King A., Laird G.K., Langford C.J., Lawlor S., Leongamornlert D.A., Lloyd D.M., Lloyd C., Loveland J.E., Lovell J., Martin S., Mashreghi-Mohammadi M., McLaren S.J., McMurray A., Milne S., Moore M.J.F., Nickerson T., Palmer S.A., Pearce A.V., Peck A.I., Pelan S., Phillimore B., Porter K.M., Rice C.M., Searle S., Sehra H.K., Shownkeen R., Skuce C.D., Smith M., Steward C.A., Sycamore N., Tester J., Thomas D.W., Tracey A., Tromans A., Tubby B., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Wilming L., Wray P.W., Wright M.W., Young L., Coulson A., Durbin R.M., Hubbard T., Sulston J.E., Beck S., Bentley D.R., Rogers J., Ross M.T.Nature 428:522-528(2004) [
PubMed] [
Europe PMC] [
Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Cited for:
NUCLEOTIDE SEQUENCE [MRNA] OF 2-365 (ISOFORMS 1 AND 2). Tissue: Brain.
Cited for: CHARACTERIZATION.
Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi
| <p>Provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.</p><p><a href='../manual/entry_name' target='_top'>More...</a></p>Entry namei | TF3A_HUMAN |
| <p>Provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.</p><p><a href='../manual/accession_numbers' target='_top'>More...</a></p>Accessioni | Q92664Primary (citable) accession number: Q92664
Secondary accession number(s): B7ZBK5, Q12963, Q13097 |
| <p>Shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the sequence are also displayed.</p><p><a href='../manual/entry_history' target='_top'>More...</a></p>Entry historyi | | Integrated into UniProtKB/Swiss-Prot: | November 1, 1997 | | Last sequence update: | February 26, 2008 | | Last modified: | February 4, 2015 | | This is version 132 of the entry and version 3 of the sequence. [Complete history] |
|
| <p>Indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).</p><p><a href='../manual/entry_status' target='_top'>More...</a></p>Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
| Annotation program | Chordata Protein Annotation Program |
| Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |
<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi
Caution
It is uncertain whether Met-1 is the initiator. Based on the lack of an in-frame AUG codon, mammalian TFIIIA may be translated from this non-AUG initiation site, which has a good Kozak context and which is well conserved among mammals.
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- Human chromosome 13
Human chromosome 13: entries, gene names and cross-references to MIM
- Human entries with polymorphisms or disease mutations
List of human entries with polymorphisms or disease mutations
- Human polymorphisms and disease mutations
Index of human polymorphisms and disease mutations
- MIM cross-references
Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
- SIMILARITY comments
Index of protein domains and families
External Data
Dasty 3<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:| 100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry. |
| 90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
| 50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |
