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Q92628

- K0232_HUMAN

UniProt

Q92628 - K0232_HUMAN

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Protein
Uncharacterized protein KIAA0232
Gene
KIAA0232
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi89 – 968ATP Reviewed prediction

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
Complete GO annotation...

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein KIAA0232
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 4

Organism-specific databases

HGNCiHGNC:28992. KIAA0232.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162392816.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 13951395Uncharacterized protein KIAA0232
PRO_0000050738Add
BLAST

Proteomic databases

MaxQBiQ92628.
PaxDbiQ92628.
PRIDEiQ92628.

PTM databases

PhosphoSiteiQ92628.

Expressioni

Gene expression databases

ArrayExpressiQ92628.
BgeeiQ92628.
CleanExiHS_KIAA0232.
GenevestigatoriQ92628.

Organism-specific databases

HPAiHPA036891.

Interactioni

Protein-protein interaction databases

BioGridi115122. 6 interactions.
IntActiQ92628. 5 interactions.
MINTiMINT-1387419.
STRINGi9606.ENSP00000303928.

Structurei

3D structure databases

ProteinModelPortaliQ92628.

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi14 – 207Poly-Ser
Compositional biasi202 – 2109Poly-Ser
Compositional biasi350 – 3589Poly-Ser

Phylogenomic databases

eggNOGiNOG78147.
HOGENOMiHOG000168299.
HOVERGENiHBG081818.
InParanoidiQ92628.
OMAiLQCAASD.
OrthoDBiEOG7DVD95.
PhylomeDBiQ92628.
TreeFamiTF328400.

Family and domain databases

InterProiIPR027871. DUF4603.
[Graphical view]
PfamiPF15376. DUF4603. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92628-1 [UniParc]FASTAAdd to Basket

« Hide

MYPICTVVVD GLPSESSSSS YPGPVSVSEM SLLHALGPVQ TWLGQELEKC     50
GIDAMIYTRY VLSLLLHDSY DYDLQEQEND IFLGWEKGAY KKWGKSKKKC 100
SDLTLEEMKK QAAVQCLRSA SDESSGIETL VEELCSRLKD LQSKQEEKIH 150
KKLEGSPSPE AELSPPAKDQ VEMYYEAFPP LSEKPVCLQE IMTVWNKSKV 200
CSYSSSSSSS TAPPASTDTS SPKDCNSESE VTKERSSEVP TTVHEKTQSK 250
SKNEKENKFS NGTIEEKPAL YKKQIRHKPE GKIRPRSWSS GSSEAGSSSS 300
GNQGELKASM KYVKVRHKAR EIRNKKGRNG QSRLSLKHGE KAERNIHTGS 350
SSSSSSGSVK QLCKRGKRPL KEIGRKDPGS TEGKDLYMEN RKDTEYKEEP 400
LWYTEPIAEY FVPLSRKSKL ETTYRNRQDT SDLTSEAVEE LSESVHGLCI 450
SNNNLHKTYL AAGTFIDGHF VEMPAVINED IDLTGTSLCS LPEDNKYLDD 500
IHLSELTHFY EVDIDQSMLD PGASETMQGE SRILNMIRQK SKENTDFEAE 550
CCIVLDGMEL QGERAIWTDS TSSVGAEGLF LQDLGNLAQF WECCSSSSGD 600
ADGESFGGDS PVRLSPILDS TVLNSHLLAG NQELFSDINE GSGINSCFSV 650
FEVQCSNSVL PFSFETLNLG NENTDSSANM LGKTQSRLLI WTKNSAFEEN 700
EHCSNLSTRT CSPWSHSEET RSDNETLNIQ FEESTQFNAE DINYVVPRVS 750
SNYVDEELLD FLQDETCQQN SRTLGEIPTL VFKKTSKLES VCGIQLEQKT 800
ENKNFETTQV CNESPHGDGY SSGVIKDIWT KMADTNSVAT VEIERTDAEL 850
FSADVNNYCC CLDAEAELET LQEPDKAVRR SEYHLWEGQK ESLEKRAFAS 900
SELSNVDGGD YTTPSKPWDV AQDKENTFIL GGVYGELKTF NSDGEWAVVP 950
PSHTKGSLLQ CAASDVVTIA GTDVFMTPGN SFAPGHRQLW KPFVSFEQND 1000
QPKSGENGLN KGFSFIFHED LLGACGNFQV EDPGLEYSFS SFDLSNPFSQ 1050
VLHVECSFEP EGIASFSPSF KPKSILCSDS DSEVFHPRIC GVDRTQYRAI 1100
RISPRTHFRP ISASELSPGG GSESEFESEK DEANIPIPSQ VDIFEDPQAD 1150
LKPLEEDAEK EGHYYGKSEL ESGKFLPRLK KSGMEKSAQT SLDSQEESTG 1200
ILSVGKQNQC LECSMNESLE IDLESSEANC KIMAQCEEEI NNFCGCKAGC 1250
QFPAYEDNPV SSGQLEEFPV LNTDIQGMNR SQEKQTWWEK ALYSPLFPAS 1300
ECEECYTNAK GESGLEEYPD AKETPSNEER LLDFNRVSSV YEARCTGERD 1350
SGAKSDGFRG KMCSSASSTS EETGSEGGGE WVGPSEEELF SRTHL 1395
Length:1,395
Mass (Da):154,789
Last modified:May 18, 2010 - v5
Checksum:i3667D0D816A51F35
GO

Sequence cautioni

The sequence BAA13221.3 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti535 – 5351N → K in BAA13221. 1 Publication
Sequence conflicti535 – 5351N → K in AAI50287. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D86985 mRNA. Translation: BAA13221.3. Different initiation.
AC106045 Genomic DNA. No translation available.
BC150286 mRNA. Translation: AAI50287.1.
CCDSiCCDS43209.1.
RefSeqiNP_001094060.1. NM_001100590.1.
NP_055558.2. NM_014743.2.
UniGeneiHs.79276.

Genome annotation databases

EnsembliENST00000307659; ENSP00000303928; ENSG00000170871.
ENST00000425103; ENSP00000413739; ENSG00000170871.
GeneIDi9778.
KEGGihsa:9778.
UCSCiuc003gjq.4. human.

Polymorphism databases

DMDMi296439501.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D86985 mRNA. Translation: BAA13221.3 . Different initiation.
AC106045 Genomic DNA. No translation available.
BC150286 mRNA. Translation: AAI50287.1 .
CCDSi CCDS43209.1.
RefSeqi NP_001094060.1. NM_001100590.1.
NP_055558.2. NM_014743.2.
UniGenei Hs.79276.

3D structure databases

ProteinModelPortali Q92628.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 115122. 6 interactions.
IntActi Q92628. 5 interactions.
MINTi MINT-1387419.
STRINGi 9606.ENSP00000303928.

PTM databases

PhosphoSitei Q92628.

Polymorphism databases

DMDMi 296439501.

Proteomic databases

MaxQBi Q92628.
PaxDbi Q92628.
PRIDEi Q92628.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000307659 ; ENSP00000303928 ; ENSG00000170871 .
ENST00000425103 ; ENSP00000413739 ; ENSG00000170871 .
GeneIDi 9778.
KEGGi hsa:9778.
UCSCi uc003gjq.4. human.

Organism-specific databases

CTDi 9778.
GeneCardsi GC04P006783.
HGNCi HGNC:28992. KIAA0232.
HPAi HPA036891.
neXtProti NX_Q92628.
PharmGKBi PA162392816.
HUGEi Search...
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG78147.
HOGENOMi HOG000168299.
HOVERGENi HBG081818.
InParanoidi Q92628.
OMAi LQCAASD.
OrthoDBi EOG7DVD95.
PhylomeDBi Q92628.
TreeFami TF328400.

Miscellaneous databases

GenomeRNAii 9778.
NextBioi 36814.

Gene expression databases

ArrayExpressi Q92628.
Bgeei Q92628.
CleanExi HS_KIAA0232.
Genevestigatori Q92628.

Family and domain databases

InterProi IPR027871. DUF4603.
[Graphical view ]
Pfami PF15376. DUF4603. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
    Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., Tanaka A., Kotani H., Miyajima N., Nomura N.
    DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Bone marrow.
  2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
    Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
    DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO 535.
  3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
    Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
    , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
    Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
  5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
    Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
    Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Cervix carcinoma.

Entry informationi

Entry nameiK0232_HUMAN
AccessioniPrimary (citable) accession number: Q92628
Secondary accession number(s): A7E2D2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: May 18, 2010
Last modified: July 9, 2014
This is version 97 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 4
    Human chromosome 4: entries, gene names and cross-references to MIM

External Data

Dasty 3

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