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Q92628

- K0232_HUMAN

UniProt

Q92628 - K0232_HUMAN

Protein

Uncharacterized protein KIAA0232

Gene

KIAA0232

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 5 (18 May 2010)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi89 – 968ATPSequence Analysis

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Uncharacterized protein KIAA0232
    Gene namesi
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 4

    Organism-specific databases

    HGNCiHGNC:28992. KIAA0232.

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA162392816.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 13951395Uncharacterized protein KIAA0232PRO_0000050738Add
    BLAST

    Proteomic databases

    MaxQBiQ92628.
    PaxDbiQ92628.
    PRIDEiQ92628.

    PTM databases

    PhosphoSiteiQ92628.

    Expressioni

    Gene expression databases

    ArrayExpressiQ92628.
    BgeeiQ92628.
    CleanExiHS_KIAA0232.
    GenevestigatoriQ92628.

    Organism-specific databases

    HPAiHPA036891.

    Interactioni

    Protein-protein interaction databases

    BioGridi115122. 6 interactions.
    IntActiQ92628. 5 interactions.
    MINTiMINT-1387419.
    STRINGi9606.ENSP00000303928.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92628.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi14 – 207Poly-Ser
    Compositional biasi202 – 2109Poly-Ser
    Compositional biasi350 – 3589Poly-Ser

    Phylogenomic databases

    eggNOGiNOG78147.
    HOGENOMiHOG000168299.
    HOVERGENiHBG081818.
    InParanoidiQ92628.
    OMAiLQCAASD.
    OrthoDBiEOG7DVD95.
    PhylomeDBiQ92628.
    TreeFamiTF328400.

    Family and domain databases

    InterProiIPR027871. DUF4603.
    [Graphical view]
    PfamiPF15376. DUF4603. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q92628-1 [UniParc]FASTAAdd to Basket

    « Hide

    MYPICTVVVD GLPSESSSSS YPGPVSVSEM SLLHALGPVQ TWLGQELEKC     50
    GIDAMIYTRY VLSLLLHDSY DYDLQEQEND IFLGWEKGAY KKWGKSKKKC 100
    SDLTLEEMKK QAAVQCLRSA SDESSGIETL VEELCSRLKD LQSKQEEKIH 150
    KKLEGSPSPE AELSPPAKDQ VEMYYEAFPP LSEKPVCLQE IMTVWNKSKV 200
    CSYSSSSSSS TAPPASTDTS SPKDCNSESE VTKERSSEVP TTVHEKTQSK 250
    SKNEKENKFS NGTIEEKPAL YKKQIRHKPE GKIRPRSWSS GSSEAGSSSS 300
    GNQGELKASM KYVKVRHKAR EIRNKKGRNG QSRLSLKHGE KAERNIHTGS 350
    SSSSSSGSVK QLCKRGKRPL KEIGRKDPGS TEGKDLYMEN RKDTEYKEEP 400
    LWYTEPIAEY FVPLSRKSKL ETTYRNRQDT SDLTSEAVEE LSESVHGLCI 450
    SNNNLHKTYL AAGTFIDGHF VEMPAVINED IDLTGTSLCS LPEDNKYLDD 500
    IHLSELTHFY EVDIDQSMLD PGASETMQGE SRILNMIRQK SKENTDFEAE 550
    CCIVLDGMEL QGERAIWTDS TSSVGAEGLF LQDLGNLAQF WECCSSSSGD 600
    ADGESFGGDS PVRLSPILDS TVLNSHLLAG NQELFSDINE GSGINSCFSV 650
    FEVQCSNSVL PFSFETLNLG NENTDSSANM LGKTQSRLLI WTKNSAFEEN 700
    EHCSNLSTRT CSPWSHSEET RSDNETLNIQ FEESTQFNAE DINYVVPRVS 750
    SNYVDEELLD FLQDETCQQN SRTLGEIPTL VFKKTSKLES VCGIQLEQKT 800
    ENKNFETTQV CNESPHGDGY SSGVIKDIWT KMADTNSVAT VEIERTDAEL 850
    FSADVNNYCC CLDAEAELET LQEPDKAVRR SEYHLWEGQK ESLEKRAFAS 900
    SELSNVDGGD YTTPSKPWDV AQDKENTFIL GGVYGELKTF NSDGEWAVVP 950
    PSHTKGSLLQ CAASDVVTIA GTDVFMTPGN SFAPGHRQLW KPFVSFEQND 1000
    QPKSGENGLN KGFSFIFHED LLGACGNFQV EDPGLEYSFS SFDLSNPFSQ 1050
    VLHVECSFEP EGIASFSPSF KPKSILCSDS DSEVFHPRIC GVDRTQYRAI 1100
    RISPRTHFRP ISASELSPGG GSESEFESEK DEANIPIPSQ VDIFEDPQAD 1150
    LKPLEEDAEK EGHYYGKSEL ESGKFLPRLK KSGMEKSAQT SLDSQEESTG 1200
    ILSVGKQNQC LECSMNESLE IDLESSEANC KIMAQCEEEI NNFCGCKAGC 1250
    QFPAYEDNPV SSGQLEEFPV LNTDIQGMNR SQEKQTWWEK ALYSPLFPAS 1300
    ECEECYTNAK GESGLEEYPD AKETPSNEER LLDFNRVSSV YEARCTGERD 1350
    SGAKSDGFRG KMCSSASSTS EETGSEGGGE WVGPSEEELF SRTHL 1395
    Length:1,395
    Mass (Da):154,789
    Last modified:May 18, 2010 - v5
    Checksum:i3667D0D816A51F35
    GO

    Sequence cautioni

    The sequence BAA13221.3 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti535 – 5351N → K in BAA13221. (PubMed:9039502)Curated
    Sequence conflicti535 – 5351N → K in AAI50287. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86985 mRNA. Translation: BAA13221.3. Different initiation.
    AC106045 Genomic DNA. No translation available.
    BC150286 mRNA. Translation: AAI50287.1.
    CCDSiCCDS43209.1.
    RefSeqiNP_001094060.1. NM_001100590.1.
    NP_055558.2. NM_014743.2.
    UniGeneiHs.79276.

    Genome annotation databases

    EnsembliENST00000307659; ENSP00000303928; ENSG00000170871.
    ENST00000425103; ENSP00000413739; ENSG00000170871.
    GeneIDi9778.
    KEGGihsa:9778.
    UCSCiuc003gjq.4. human.

    Polymorphism databases

    DMDMi296439501.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86985 mRNA. Translation: BAA13221.3 . Different initiation.
    AC106045 Genomic DNA. No translation available.
    BC150286 mRNA. Translation: AAI50287.1 .
    CCDSi CCDS43209.1.
    RefSeqi NP_001094060.1. NM_001100590.1.
    NP_055558.2. NM_014743.2.
    UniGenei Hs.79276.

    3D structure databases

    ProteinModelPortali Q92628.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 115122. 6 interactions.
    IntActi Q92628. 5 interactions.
    MINTi MINT-1387419.
    STRINGi 9606.ENSP00000303928.

    PTM databases

    PhosphoSitei Q92628.

    Polymorphism databases

    DMDMi 296439501.

    Proteomic databases

    MaxQBi Q92628.
    PaxDbi Q92628.
    PRIDEi Q92628.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000307659 ; ENSP00000303928 ; ENSG00000170871 .
    ENST00000425103 ; ENSP00000413739 ; ENSG00000170871 .
    GeneIDi 9778.
    KEGGi hsa:9778.
    UCSCi uc003gjq.4. human.

    Organism-specific databases

    CTDi 9778.
    GeneCardsi GC04P006783.
    HGNCi HGNC:28992. KIAA0232.
    HPAi HPA036891.
    neXtProti NX_Q92628.
    PharmGKBi PA162392816.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG78147.
    HOGENOMi HOG000168299.
    HOVERGENi HBG081818.
    InParanoidi Q92628.
    OMAi LQCAASD.
    OrthoDBi EOG7DVD95.
    PhylomeDBi Q92628.
    TreeFami TF328400.

    Miscellaneous databases

    GenomeRNAii 9778.
    NextBioi 36814.

    Gene expression databases

    ArrayExpressi Q92628.
    Bgeei Q92628.
    CleanExi HS_KIAA0232.
    Genevestigatori Q92628.

    Family and domain databases

    InterProi IPR027871. DUF4603.
    [Graphical view ]
    Pfami PF15376. DUF4603. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
      Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., Tanaka A., Kotani H., Miyajima N., Nomura N.
      DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Bone marrow.
    2. "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D., Okazaki N., Yamakawa H., Kikuno R., Ohara O., Nagase T.
      DNA Res. 9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: SEQUENCE REVISION TO 535.
    3. "Generation and annotation of the DNA sequences of human chromosomes 2 and 4."
      Hillier L.W., Graves T.A., Fulton R.S., Fulton L.A., Pepin K.H., Minx P., Wagner-McPherson C., Layman D., Wylie K., Sekhon M., Becker M.C., Fewell G.A., Delehaunty K.D., Miner T.L., Nash W.E., Kremitzki C., Oddy L., Du H.
      , Sun H., Bradshaw-Cordum H., Ali J., Carter J., Cordes M., Harris A., Isak A., van Brunt A., Nguyen C., Du F., Courtney L., Kalicki J., Ozersky P., Abbott S., Armstrong J., Belter E.A., Caruso L., Cedroni M., Cotton M., Davidson T., Desai A., Elliott G., Erb T., Fronick C., Gaige T., Haakenson W., Haglund K., Holmes A., Harkins R., Kim K., Kruchowski S.S., Strong C.M., Grewal N., Goyea E., Hou S., Levy A., Martinka S., Mead K., McLellan M.D., Meyer R., Randall-Maher J., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Shah N., Swearengen-Shahid S., Snider J., Strong J.T., Thompson J., Yoakum M., Leonard S., Pearman C., Trani L., Radionenko M., Waligorski J.E., Wang C., Rock S.M., Tin-Wollam A.-M., Maupin R., Latreille P., Wendl M.C., Yang S.-P., Pohl C., Wallis J.W., Spieth J., Bieri T.A., Berkowicz N., Nelson J.O., Osborne J., Ding L., Meyer R., Sabo A., Shotland Y., Sinha P., Wohldmann P.E., Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Jones T.A., She X., Ciccarelli F.D., Izaurralde E., Taylor J., Schmutz J., Myers R.M., Cox D.R., Huang X., McPherson J.D., Mardis E.R., Clifton S.W., Warren W.C., Chinwalla A.T., Eddy S.R., Marra M.A., Ovcharenko I., Furey T.S., Miller W., Eichler E.E., Bork P., Suyama M., Torrents D., Waterston R.H., Wilson R.K.
      Nature 434:724-731(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    5. "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P., Mann M.
      Cell 127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Cervix carcinoma.

    Entry informationi

    Entry nameiK0232_HUMAN
    AccessioniPrimary (citable) accession number: Q92628
    Secondary accession number(s): A7E2D2
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: May 18, 2010
    Last modified: October 1, 2014
    This is version 98 of the entry and version 5 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 4
      Human chromosome 4: entries, gene names and cross-references to MIM

    External Data

    Dasty 3