Q92617 (NPPL3_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Nuclear pore complex-interacting protein-like 3

Alternative name(s):
Protein pps22-1

Gene names

Name:	NPIPL3
Synonyms:	KIAA0220

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	1050 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subcellular location	Membrane; Single-pass membrane protein Potential.
Sequence similarities	Belongs to the NPIP family.
Sequence caution	The sequence BAA13210.2 differs from that shown. Reason: Frameshift at position 203. The sequence BAD92869.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Membrane
Coding sequence diversity	Alternative splicing
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q92617-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q92617-2)

The sequence of this isoform differs from the canonical sequence as follows:
     515-886: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q92617-3)

The sequence of this isoform differs from the canonical sequence as follows:
     1-40: MVKLSIVLTPQFLSHDQGQLTKELQQHVKSVTCPCEYLRK → MFCCLGYEWLSGGCKTWHSAW
     577-868: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q92617-4)

The sequence of this isoform differs from the canonical sequence as follows:
     1-216: Missing.
     515-928: Missing.

Isoform 5 (identifier: Q92617-5)

The sequence of this isoform differs from the canonical sequence as follows:
     290-327: Missing.
     413-576: Missing.
     785-826: ERLRGPLPPS...SADDNIKTPA → GRFHPQRMII...ISRHLPSVCG

Note: No experimental confirmation available.

Isoform 6 (identifier: Q92617-6)

The sequence of this isoform differs from the canonical sequence as follows:
     947-974: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1050	1050	Nuclear pore complex-interacting protein-like 3		PRO_0000050735
Regions
	Transmembrane	63 – 87	25	Helical; Potential
Natural variations
	Alternative sequence	1 – 216	216	Missing in isoform 4.		VSP_021832
	Alternative sequence	1 – 40	40	MVKLS…EYLRK → MFCCLGYEWLSGGCKTWHSA W in isoform 3.		VSP_021833
	Alternative sequence	290 – 327	38	Missing in isoform 5.		VSP_021834
	Alternative sequence	413 – 576	164	Missing in isoform 5.		VSP_021835
	Alternative sequence	515 – 928	414	Missing in isoform 4.		VSP_021836
	Alternative sequence	515 – 886	372	Missing in isoform 2.		VSP_021837
	Alternative sequence	577 – 868	292	Missing in isoform 3.		VSP_021838
	Alternative sequence	785 – 826	42	ERLRG…IKTPA → GRFHPQRMIISRHLPSVSSL PFHPQLHPQQMIISRHLPSV CG in isoform 5.		VSP_021839
	Alternative sequence	947 – 974	28	Missing in isoform 6.		VSP_033367
Experimental info
	Sequence conflict	21	1	T → S in AAH36263. Ref.4
	Sequence conflict	138	1	G → V in AAH36263. Ref.4
	Sequence conflict	388	1	P → L in AAH36263. Ref.4
	Sequence conflict	521	1	A → P in BAA13210. Ref.1
	Sequence conflict	526	1	A → APPSA in BAA13210. Ref.1
	Sequence conflict	584	1	Missing in BAD92869. Ref.2
	Sequence conflict	610 – 612	3	HLP → YLL in BAA13210. Ref.1
	Sequence conflict	617	1	G → F in BAA13210. Ref.1
	Sequence conflict	621 – 623	3	PQQ → HQP in BAA13210. Ref.1
	Sequence conflict	622 – 623	2	QQ → ER in BAD92869. Ref.2
	Sequence conflict	664	1	Q → E in BAD92869. Ref.2
	Sequence conflict	675	1	V → I in BAA13210. Ref.1
	Sequence conflict	707	1	Q → R in BAA13210. Ref.1
	Sequence conflict	707	1	Q → R in BAD92869. Ref.2
	Sequence conflict	766	1	P → T in BAA13210. Ref.1
	Sequence conflict	825	1	P → S in AAH73943. Ref.4

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 25, 2008. Version 5. Checksum: 342657B7685C9167	FASTA	1,050	116,847
	10 20 30 40 50 60 MVKLSIVLTP QFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHHH RGTDFGGSPW 70 80 90 100 110 120 LHVIIAFPTS YKVVITLWIV YLWVSLLKTI FWSRNGHDGS TDVQQRAWRS NRRRQEGLRS 130 140 150 160 170 180 ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINHHD KINGKRKTAR 190 200 210 220 230 240 KQKMFQRAQE LRRRAEDYHK CKIPPSARKA LCNWVRMAAA EHRHSSGLPY WPYLTAETLK 250 260 270 280 290 300 NRMGHQPPPP TQQHSITDNS LSLKTPPECL LTPLPPSADD NLKTPPECVL TPLPPSADDN 310 320 330 340 350 360 LKTPPECVLT PLPPSADDNL KTPPECLLTP LPPSADDNLK TPPECLLTPL PPSALPSAPP 370 380 390 400 410 420 SADDNLKTRA ECLLHPLPPS ADDNLKTPSE RQLTPLPPSA PPSADDNIKT PAERLRGPLP 430 440 450 460 470 480 PSADDNLKTP SERQLTPLPP SAPPSADDNI KTPAERLRGP LPPSADDNLK TPSERQLTPL 490 500 510 520 530 540 PPSAPPSADD NIKTPAERLR GPLPPSADDN LKTPSERQLT ALPPSADDNI KTPAERLRGP 550 560 570 580 590 600 LPPSADDNLK TPSERQLTPL PPSAPPSADD NIKTPAFHPQ RMIISRHLPS VSSLPFHPQL 610 620 630 640 650 660 HPQQMIISRH LPSVCGGRFH PQQMIISRHL PSVSSLPFHP QLHPQQMIIS RHLPSVCGGR 670 680 690 700 710 720 FHPQRMIISR HLPSVSSLPF HPQLHPQQMI ISRHLPSVCG GRFHPQQMII SRHLPSVSSL 730 740 750 760 770 780 PFHPQLHPQQ MIISRHLPSV CGGRFHPQRM IISRHLPSVS SLPFHPQLHP QQMIISRHLP 790 800 810 820 830 840 SVCGERLRGP LPPSADDNLK TPSERQLTPL PPSAPPSADD NIKTPAERLR GPLPPSADDN 850 860 870 880 890 900 LKTPSERQLT PLPPSAPPSA DDNIKTPAER LRGPLPPSAD DNLKTPSERQ LTPLPPSAPP 910 920 930 940 950 960 SADDNIKTPA ERLRGPLPPS ADDNLKTPPL ATQEAEAEKP RKPKRQRAAE MEPPPEPKRR 970 980 990 1000 1010 1020 RVGDVEPSRK PKRRRAADVE PSSPEPKRRR VGDVEPSRKP KRRRAADVEP SSPEPKRRRV 1030 1040 1050 GDVEPSRKPK RRRAADVEPS LPEPKRRRLS
	Isoform 2 [UniParc]. Checksum: B2B36F44C4945E2E	FASTA	678	75,695
	10 20 30 40 50 60 MVKLSIVLTP QFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHHH RGTDFGGSPW 70 80 90 100 110 120 LHVIIAFPTS YKVVITLWIV YLWVSLLKTI FWSRNGHDGS TDVQQRAWRS NRRRQEGLRS 130 140 150 160 170 180 ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINHHD KINGKRKTAR 190 200 210 220 230 240 KQKMFQRAQE LRRRAEDYHK CKIPPSARKA LCNWVRMAAA EHRHSSGLPY WPYLTAETLK 250 260 270 280 290 300 NRMGHQPPPP TQQHSITDNS LSLKTPPECL LTPLPPSADD NLKTPPECVL TPLPPSADDN 310 320 330 340 350 360 LKTPPECVLT PLPPSADDNL KTPPECLLTP LPPSADDNLK TPPECLLTPL PPSALPSAPP 370 380 390 400 410 420 SADDNLKTRA ECLLHPLPPS ADDNLKTPSE RQLTPLPPSA PPSADDNIKT PAERLRGPLP 430 440 450 460 470 480 PSADDNLKTP SERQLTPLPP SAPPSADDNI KTPAERLRGP LPPSADDNLK TPSERQLTPL 490 500 510 520 530 540 PPSAPPSADD NIKTPAERLR GPLPPSADDN LKTPSERQLT PLPPSAPPSA DDNIKTPAER 550 560 570 580 590 600 LRGPLPPSAD DNLKTPPLAT QEAEAEKPRK PKRQRAAEME PPPEPKRRRV GDVEPSRKPK 610 620 630 640 650 660 RRRAADVEPS SPEPKRRRVG DVEPSRKPKR RRAADVEPSS PEPKRRRVGD VEPSRKPKRR 670 RAADVEPSLP EPKRRRLS
	Isoform 3 [UniParc]. Checksum: ACF7138A80BF3264	FASTA	739	82,041
	10 20 30 40 50 60 MFCCLGYEWL SGGCKTWHSA WVINTLADHH HRGTDFGGSP WLHVIIAFPT SYKVVITLWI 70 80 90 100 110 120 VYLWVSLLKT IFWSRNGHDG STDVQQRAWR SNRRRQEGLR SICMHTKKRV SSFRGNKIGL 130 140 150 160 170 180 KDVITLRRHV ETKVRAKIRK RKVTTKINHH DKINGKRKTA RKQKMFQRAQ ELRRRAEDYH 190 200 210 220 230 240 KCKIPPSARK ALCNWVRMAA AEHRHSSGLP YWPYLTAETL KNRMGHQPPP PTQQHSITDN 250 260 270 280 290 300 SLSLKTPPEC LLTPLPPSAD DNLKTPPECV LTPLPPSADD NLKTPPECVL TPLPPSADDN 310 320 330 340 350 360 LKTPPECLLT PLPPSADDNL KTPPECLLTP LPPSALPSAP PSADDNLKTR AECLLHPLPP 370 380 390 400 410 420 SADDNLKTPS ERQLTPLPPS APPSADDNIK TPAERLRGPL PPSADDNLKT PSERQLTPLP 430 440 450 460 470 480 PSAPPSADDN IKTPAERLRG PLPPSADDNL KTPSERQLTP LPPSAPPSAD DNIKTPAERL 490 500 510 520 530 540 RGPLPPSADD NLKTPSERQL TALPPSADDN IKTPAERLRG PLPPSADDNL KTPSERQLTP 550 560 570 580 590 600 LPPSAPPSAD DNIKTPAERL RGPLPPSADD NLKTPSERQL TPLPPSAPPS ADDNIKTPAE 610 620 630 640 650 660 RLRGPLPPSA DDNLKTPPLA TQEAEAEKPR KPKRQRAAEM EPPPEPKRRR VGDVEPSRKP 670 680 690 700 710 720 KRRRAADVEP SSPEPKRRRV GDVEPSRKPK RRRAADVEPS SPEPKRRRVG DVEPSRKPKR 730 RRAADVEPSL PEPKRRRLS
	Isoform 4 [UniParc]. Checksum: E342C1BEDD566725	FASTA	420	45,809
	10 20 30 40 50 60 MAAAEHRHSS GLPYWPYLTA ETLKNRMGHQ PPPPTQQHSI TDNSLSLKTP PECLLTPLPP 70 80 90 100 110 120 SADDNLKTPP ECVLTPLPPS ADDNLKTPPE CVLTPLPPSA DDNLKTPPEC LLTPLPPSAD 130 140 150 160 170 180 DNLKTPPECL LTPLPPSALP SAPPSADDNL KTRAECLLHP LPPSADDNLK TPSERQLTPL 190 200 210 220 230 240 PPSAPPSADD NIKTPAERLR GPLPPSADDN LKTPSERQLT PLPPSAPPSA DDNIKTPAER 250 260 270 280 290 300 LRGPLPPSAD DNLKTPSERQ LTPLPPSAPP SADDNIKTPA ERLRGPLPPS ADDNLKTPPL 310 320 330 340 350 360 ATQEAEAEKP RKPKRQRAAE MEPPPEPKRR RVGDVEPSRK PKRRRAADVE PSSPEPKRRR 370 380 390 400 410 420 VGDVEPSRKP KRRRAADVEP SSPEPKRRRV GDVEPSRKPK RRRAADVEPS LPEPKRRRLS
	Isoform 5 [UniParc]. Checksum: A4E0A4C64C87928D	FASTA	848	95,824
	10 20 30 40 50 60 MVKLSIVLTP QFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHHH RGTDFGGSPW 70 80 90 100 110 120 LHVIIAFPTS YKVVITLWIV YLWVSLLKTI FWSRNGHDGS TDVQQRAWRS NRRRQEGLRS 130 140 150 160 170 180 ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINHHD KINGKRKTAR 190 200 210 220 230 240 KQKMFQRAQE LRRRAEDYHK CKIPPSARKA LCNWVRMAAA EHRHSSGLPY WPYLTAETLK 250 260 270 280 290 300 NRMGHQPPPP TQQHSITDNS LSLKTPPECL LTPLPPSADD NLKTPPECVL TPLPPSADDN 310 320 330 340 350 360 LKTPPECLLT PLPPSALPSA PPSADDNLKT RAECLLHPLP PSADDNLKTP SERQLTPLPP 370 380 390 400 410 420 SAPPSADDNI KTPAFHPQRM IISRHLPSVS SLPFHPQLHP QQMIISRHLP SVCGGRFHPQ 430 440 450 460 470 480 QMIISRHLPS VSSLPFHPQL HPQQMIISRH LPSVCGGRFH PQRMIISRHL PSVSSLPFHP 490 500 510 520 530 540 QLHPQQMIIS RHLPSVCGGR FHPQQMIISR HLPSVSSLPF HPQLHPQQMI ISRHLPSVCG 550 560 570 580 590 600 GRFHPQRMII SRHLPSVSSL PFHPQLHPQQ MIISRHLPSV CGGRFHPQRM IISRHLPSVS 610 620 630 640 650 660 SLPFHPQLHP QQMIISRHLP SVCGERLRGP LPPSADDNLK TPSERQLTPL PPSAPPSADD 670 680 690 700 710 720 NIKTPAERLR GPLPPSADDN LKTPSERQLT PLPPSAPPSA DDNIKTPAER LRGPLPPSAD 730 740 750 760 770 780 DNLKTPPLAT QEAEAEKPRK PKRQRAAEME PPPEPKRRRV GDVEPSRKPK RRRAADVEPS 790 800 810 820 830 840 SPEPKRRRVG DVEPSRKPKR RRAADVEPSS PEPKRRRVGD VEPSRKPKRR RAADVEPSLP EPKRRRLS
	Isoform 6 [UniParc]. Checksum: DC9A8F9964D0B7E4	FASTA	1,022	113,539
	10 20 30 40 50 60 MVKLSIVLTP QFLSHDQGQL TKELQQHVKS VTCPCEYLRK VINTLADHHH RGTDFGGSPW 70 80 90 100 110 120 LHVIIAFPTS YKVVITLWIV YLWVSLLKTI FWSRNGHDGS TDVQQRAWRS NRRRQEGLRS 130 140 150 160 170 180 ICMHTKKRVS SFRGNKIGLK DVITLRRHVE TKVRAKIRKR KVTTKINHHD KINGKRKTAR 190 200 210 220 230 240 KQKMFQRAQE LRRRAEDYHK CKIPPSARKA LCNWVRMAAA EHRHSSGLPY WPYLTAETLK 250 260 270 280 290 300 NRMGHQPPPP TQQHSITDNS LSLKTPPECL LTPLPPSADD NLKTPPECVL TPLPPSADDN 310 320 330 340 350 360 LKTPPECVLT PLPPSADDNL KTPPECLLTP LPPSADDNLK TPPECLLTPL PPSALPSAPP 370 380 390 400 410 420 SADDNLKTRA ECLLHPLPPS ADDNLKTPSE RQLTPLPPSA PPSADDNIKT PAERLRGPLP 430 440 450 460 470 480 PSADDNLKTP SERQLTPLPP SAPPSADDNI KTPAERLRGP LPPSADDNLK TPSERQLTPL 490 500 510 520 530 540 PPSAPPSADD NIKTPAERLR GPLPPSADDN LKTPSERQLT ALPPSADDNI KTPAERLRGP 550 560 570 580 590 600 LPPSADDNLK TPSERQLTPL PPSAPPSADD NIKTPAFHPQ RMIISRHLPS VSSLPFHPQL 610 620 630 640 650 660 HPQQMIISRH LPSVCGGRFH PQQMIISRHL PSVSSLPFHP QLHPQQMIIS RHLPSVCGGR 670 680 690 700 710 720 FHPQRMIISR HLPSVSSLPF HPQLHPQQMI ISRHLPSVCG GRFHPQQMII SRHLPSVSSL 730 740 750 760 770 780 PFHPQLHPQQ MIISRHLPSV CGGRFHPQRM IISRHLPSVS SLPFHPQLHP QQMIISRHLP 790 800 810 820 830 840 SVCGERLRGP LPPSADDNLK TPSERQLTPL PPSAPPSADD NIKTPAERLR GPLPPSADDN 850 860 870 880 890 900 LKTPSERQLT PLPPSAPPSA DDNIKTPAER LRGPLPPSAD DNLKTPSERQ LTPLPPSAPP 910 920 930 940 950 960 SADDNIKTPA ERLRGPLPPS ADDNLKTPPL ATQEAEAEKP RKPKRQRAAD VEPSSPEPKR 970 980 990 1000 1010 1020 RRVGDVEPSR KPKRRRAADV EPSSPEPKRR RVGDVEPSRK PKRRRAADVE PSLPEPKRRR LS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain." Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., Tanaka A., Kotani H., Miyajima N., Nomura N. DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Tissue: Bone marrow.
[2]	Totoki Y., Toyoda A., Takeda T., Sakaki Y., Tanaka A., Yokoyama S., Ohara O., Nagase T., Kikuno R.F. Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 5). Tissue: Spleen.
[3]	"The sequence and analysis of duplication-rich human chromosome 16." Martin J., Han C., Gordon L.A., Terry A., Prabhakar S., She X., Xie G., Hellsten U., Chan Y.M., Altherr M., Couronne O., Aerts A., Bajorek E., Black S., Blumer H., Branscomb E., Brown N.C., Bruno W.J. , Buckingham J.M., Callen D.F., Campbell C.S., Campbell M.L., Campbell E.W., Caoile C., Challacombe J.F., Chasteen L.A., Chertkov O., Chi H.C., Christensen M., Clark L.M., Cohn J.D., Denys M., Detter J.C., Dickson M., Dimitrijevic-Bussod M., Escobar J., Fawcett J.J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Goodwin L.A., Grady D.L., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Hildebrand C.E., Huang W., Israni S., Jett J., Jewett P.B., Kadner K., Kimball H., Kobayashi A., Krawczyk M.-C., Leyba T., Longmire J.L., Lopez F., Lou Y., Lowry S., Ludeman T., Manohar C.F., Mark G.A., McMurray K.L., Meincke L.J., Morgan J., Moyzis R.K., Mundt M.O., Munk A.C., Nandkeshwar R.D., Pitluck S., Pollard M., Predki P., Parson-Quintana B., Ramirez L., Rash S., Retterer J., Ricke D.O., Robinson D.L., Rodriguez A., Salamov A., Saunders E.H., Scott D., Shough T., Stallings R.L., Stalvey M., Sutherland R.D., Tapia R., Tesmer J.G., Thayer N., Thompson L.S., Tice H., Torney D.C., Tran-Gyamfi M., Tsai M., Ulanovsky L.E., Ustaszewska A., Vo N., White P.S., Williams A.L., Wills P.L., Wu J.-R., Wu K., Yang J., DeJong P., Bruce D., Doggett N.A., Deaven L., Schmutz J., Grimwood J., Richardson P., Rokhsar D.S., Eichler E.E., Gilna P., Lucas S.M., Myers R.M., Rubin E.M., Pennacchio L.A. Nature 432:988-994(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 2; 3 AND 4), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 690-1050 (ISOFORM 1). Tissue: Lymph, Mammary carcinoma, Pancreas and PNS.
[5]	"Cloning and identification of a new protein coding gene pps22-1 binding with promoter DNA of pre-pre-S gene of hepatitis B virus." Huang Y.-P., Cheng J., Yang Y.-J. Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 917-1050 (ISOFORM 6).

Cross-references

Sequence databases
EMBL GenBank DDBJ	D86974 mRNA. Translation: BAA13210.2. Sequence problems. AB209632 Transcribed RNA. Translation: BAD92869.1. Different initiation. AC008740 Genomic DNA. No translation available. BC036263 mRNA. Translation: AAH36263.1. BC061522 mRNA. Translation: AAH61522.1. BC073943 mRNA. Translation: AAH73943.1. BC094882 mRNA. Translation: AAH94882.1. AY498718 mRNA. Translation: AAS48701.1.
IPI	IPI00807454. IPI00807499. IPI00807535. IPI00807565. IPI00890704. IPI00956264.
RefSeq	NP_569731.2. NM_130464.2.
UniGene	Hs.611072. Hs.632865. Hs.656872. Hs.720286.
3D structure databases
ProteinModelPortal	Q92617.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q92617. 2 interactions.
STRING	9606.ENSP00000399107.
PTM databases
PhosphoSite	Q92617.
Polymorphism databases
DMDM	215274263.
Proteomic databases
PaxDb	Q92617.
PRIDE	Q92617.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000542817; ENSP00000444096; ENSG00000169246.
GeneID	23117.
KEGG	hsa:23117.
UCSC	uc002djq.3. human. uc021tem.1. human.
Organism-specific databases
CTD	23117.
GeneCards	GC16M021413.
H-InvDB	HIX0173283.
HGNC	HGNC:28989. NPIPL3.
neXtProt	NX_Q92617.
PharmGKB	PA164724182.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG12793.
HOVERGEN	HBG052821.
Gene expression databases
ArrayExpress	Q92617.
Bgee	Q92617.
Genevestigator	Q92617.
GermOnline	ENSG00000198064. Homo sapiens.
Family and domain databases
InterPro	IPR009443. NPIP. [Graphical view]
PANTHER	PTHR15438. PTHR15438. 1 hit.
Pfam	PF06409. NPIP. 12 hits. [Graphical view]
ProtoNet	Search...
Other
GenomeRNAi	23117.
NextBio	44328.

Entry information

Entry name

NPPL3_HUMAN

Accession

Primary (citable) accession number: Q92617
Secondary accession number(s): O43332 , Q504Q6, Q59F29, Q6GMR1, Q6P7T2, Q6PIE2, Q6RH21

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 21, 2001
Last sequence update:	November 25, 2008
Last modified:	May 1, 2013
This is version 89 of the entry and version 5 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.