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Protein

DnaJ homolog subfamily C member 12

Gene

Dnajc12

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
DnaJ homolog subfamily C member 12
Alternative name(s):
J domain-containing protein 1
Gene namesi
Name:Dnajc12
Synonyms:Jdp1
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 20

Organism-specific databases

RGDi1591898. Dnajc12.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 198198DnaJ homolog subfamily C member 12PRO_0000071068Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei160 – 1601PhosphoserineBy similarity
Modified residuei166 – 1661PhosphoserineBy similarity
Modified residuei182 – 1821PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ925T0.
PRIDEiQ925T0.

Expressioni

Gene expression databases

GenevisibleiQ925T0. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000426.

Structurei

3D structure databases

ProteinModelPortaliQ925T0.
SMRiQ925T0. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 7966JPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 J domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0691. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00550000074688.
HOGENOMiHOG000017161.
HOVERGENiHBG051379.
InParanoidiQ925T0.
KOiK09532.
OMAiYWHLRFR.
OrthoDBiEOG7DRJ4W.
PhylomeDBiQ925T0.
TreeFamiTF105171.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q925T0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDAILNYRPE GSEDYYTLLG CDELSSVEQI LAEFKVRALE CHPDKHPENS
60 70 80 90 100
KAVETFQKLQ KAKEILSNAE SRARYDHWRR SQMSMSFEQW EALADSVKTS
110 120 130 140 150
MHWAVRSKKD LMLEGSEQTY TNTAQNKERS EQRETKQGDP DSTPEKMMQK
160 170 180 190
ESESPEKGIS PQNPDSPGLS DWNCGHLHFR WSGDTPSELL RKFRNYEI
Length:198
Mass (Da):22,978
Last modified:December 1, 2001 - v1
Checksum:i50EB88BFE2EF88A9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB062135 mRNA. Translation: BAB55876.1.
BC100072 mRNA. Translation: AAI00073.1.
RefSeqiNP_001029204.1. NM_001034032.1.
UniGeneiRn.9583.

Genome annotation databases

EnsembliENSRNOT00000082430; ENSRNOP00000075353; ENSRNOG00000051960.
GeneIDi619393.
KEGGirno:619393.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB062135 mRNA. Translation: BAB55876.1.
BC100072 mRNA. Translation: AAI00073.1.
RefSeqiNP_001029204.1. NM_001034032.1.
UniGeneiRn.9583.

3D structure databases

ProteinModelPortaliQ925T0.
SMRiQ925T0. Positions 1-100.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000000426.

Proteomic databases

PaxDbiQ925T0.
PRIDEiQ925T0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000082430; ENSRNOP00000075353; ENSRNOG00000051960.
GeneIDi619393.
KEGGirno:619393.

Organism-specific databases

CTDi56521.
RGDi1591898. Dnajc12.

Phylogenomic databases

eggNOGiKOG0691. Eukaryota.
COG2214. LUCA.
GeneTreeiENSGT00550000074688.
HOGENOMiHOG000017161.
HOVERGENiHBG051379.
InParanoidiQ925T0.
KOiK09532.
OMAiYWHLRFR.
OrthoDBiEOG7DRJ4W.
PhylomeDBiQ925T0.
TreeFamiTF105171.

Miscellaneous databases

PROiQ925T0.

Gene expression databases

GenevisibleiQ925T0. RN.

Family and domain databases

Gene3Di1.10.287.110. 1 hit.
InterProiIPR001623. DnaJ_domain.
[Graphical view]
PfamiPF00226. DnaJ. 1 hit.
[Graphical view]
PRINTSiPR00625. JDOMAIN.
SMARTiSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMiSSF46565. SSF46565. 1 hit.
PROSITEiPS50076. DNAJ_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths."
    Lee J., Hahn Y., Yun J.H., Mita K., Chung J.H.
    Biochim. Biophys. Acta 1491:355-363(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Liver.

Entry informationi

Entry nameiDJC12_RAT
AccessioniPrimary (citable) accession number: Q925T0
Secondary accession number(s): Q498U2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 2003
Last sequence update: December 1, 2001
Last modified: July 6, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.