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Protein

C-type lectin domain family 2 member D5

Gene

Ocil

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Lectin-type cell surface receptor.By similarity

GO - Molecular functioni

Keywordsi

Molecular functionReceptor
LigandLectin

Names & Taxonomyi

Protein namesi
Recommended name:
C-type lectin domain family 2 member D5
Alternative name(s):
Osteoclast inhibitory lectin
Gene namesi
Name:Ocil
Synonyms:Clec2d5
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Unplaced

Organism-specific databases

RGDi620070. Ocil.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 76CytoplasmicSequence analysisAdd BLAST76
Transmembranei77 – 97Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini98 – 233ExtracellularSequence analysisAdd BLAST136

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003152941 – 233C-type lectin domain family 2 member D5Add BLAST233

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi132N-linked (GlcNAc...) asparagineSequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

PRIDEiQ925N7.

Structurei

3D structure databases

ProteinModelPortaliQ925N7.
SMRiQ925N7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini119 – 228C-type lectinPROSITE-ProRule annotationAdd BLAST110

Keywords - Domaini

Signal-anchor, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000060206.
HOVERGENiHBG107716.
InParanoidiQ925N7.
PhylomeDBiQ925N7.
TreeFamiTF351467.

Family and domain databases

CDDicd03593. CLECT_NK_receptors_like. 1 hit.
Gene3Di3.10.100.10. 1 hit.
InterProiView protein in InterPro
IPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR016187. CTDL_fold.
IPR033992. NKR-like_CTLD.
PfamiView protein in Pfam
PF00059. Lectin_C. 1 hit.
SMARTiView protein in SMART
SM00034. CLECT. 1 hit.
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiView protein in PROSITE
PS50041. C_TYPE_LECTIN_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q925N7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPSSAHLQDP PPLLSRTLTQ NEGQTSLRQS SSCGPSAASA SESLSGSTES
60 70 80 90 100
RIPHSKMLQG KLPRNIPLEY PAGLYCCYVV IIVLSVAVVA LSVALSVKKT
110 120 130 140 150
AQISTINTYA ACPRNWIGVG NKCFYFNEIP SNWTLSQTLC KEQGAELARF
160 170 180 190 200
DTEEELNFLR RYKGSSGYWF GLHRESSAHP WKWTDNTEYN NSVSIGGDEK
210 220 230
HGFLSDNGFS SGRGYIVRKS ICRKPNSYTS QCL
Length:233
Mass (Da):25,686
Last modified:December 1, 2001 - v1
Checksum:i56C7B6D08171CDEF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF321552 mRNA. Translation: AAK50880.1.
EF100688 mRNA. Translation: ABO15828.1.
RefSeqiNP_569086.1. NM_130402.2.
XP_008761531.1. XM_008763309.2.
UniGeneiRn.22573.

Genome annotation databases

GeneIDi113937.
KEGGirno:113937.
UCSCiRGD:620070. rat.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiCL2D5_RAT
AccessioniPrimary (citable) accession number: Q925N7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: December 1, 2001
Last modified: May 10, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome