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Protein

Small muscular protein

Gene

Smpx

Organism
Rattus norvegicus (Rat)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair.By similarity

Names & Taxonomyi

Protein namesi
Recommended name:
Small muscular protein
Alternative name(s):
Stretch-responsive skeletal muscle protein
Gene namesi
Name:Smpx
Synonyms:Srmx
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus
ProteomesiUP000002494 Componenti: Chromosome X

Organism-specific databases

RGDi69233. Smpx.

Subcellular locationi

GO - Cellular componenti

  1. costamere Source: Ensembl
  2. M band Source: Ensembl
  3. muscle tendon junction Source: Ensembl
  4. nucleus Source: Ensembl
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8585Small muscular proteinPRO_0000071981Add
BLAST

Proteomic databases

PaxDbiQ925F0.
PRIDEiQ925F0.

Expressioni

Gene expression databases

GenevestigatoriQ925F0.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010027.

Family & Domainsi

Sequence similaritiesi

Belongs to the SMPX family.Curated

Phylogenomic databases

eggNOGiNOG85281.
GeneTreeiENSGT00390000017542.
HOGENOMiHOG000120124.
HOVERGENiHBG059051.
InParanoidiQ925F0.
OMAiELRWVTK.
OrthoDBiEOG7M6DB6.
PhylomeDBiQ925F0.
TreeFamiTF338181.

Family and domain databases

InterProiIPR029268. Chisel.
[Graphical view]
PANTHERiPTHR17416. PTHR17416. 1 hit.
PfamiPF15355. Chisel. 1 hit.
[Graphical view]
ProDomiPD352676. PD352676. 1 hit.
[Graphical view] [Entries sharing at least one domain]

Sequencei

Sequence statusi: Complete.

Q925F0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKQPISNVR SIQANINIPM GAFRPGAGQP PRRKESTPGT AEGAPATPEE
60 70 80
KKPVPGMKKF PGPVVNLSEI QNVKSELKYV PKGEQ
Length:85
Mass (Da):9,121
Last modified:December 1, 2001 - v1
Checksum:i52654F8C790C932C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF364071 mRNA. Translation: AAK50399.1.
RefSeqiNP_445847.1. NM_053395.1.
XP_006257007.1. XM_006256945.2.
UniGeneiRn.4123.

Genome annotation databases

EnsembliENSRNOT00000010027; ENSRNOP00000010027; ENSRNOG00000007495.
GeneIDi84416.
KEGGirno:84416.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF364071 mRNA. Translation: AAK50399.1.
RefSeqiNP_445847.1. NM_053395.1.
XP_006257007.1. XM_006256945.2.
UniGeneiRn.4123.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000010027.

Proteomic databases

PaxDbiQ925F0.
PRIDEiQ925F0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSRNOT00000010027; ENSRNOP00000010027; ENSRNOG00000007495.
GeneIDi84416.
KEGGirno:84416.

Organism-specific databases

CTDi23676.
RGDi69233. Smpx.

Phylogenomic databases

eggNOGiNOG85281.
GeneTreeiENSGT00390000017542.
HOGENOMiHOG000120124.
HOVERGENiHBG059051.
InParanoidiQ925F0.
OMAiELRWVTK.
OrthoDBiEOG7M6DB6.
PhylomeDBiQ925F0.
TreeFamiTF338181.

Miscellaneous databases

NextBioi616894.
PROiQ925F0.

Gene expression databases

GenevestigatoriQ925F0.

Family and domain databases

InterProiIPR029268. Chisel.
[Graphical view]
PANTHERiPTHR17416. PTHR17416. 1 hit.
PfamiPF15355. Chisel. 1 hit.
[Graphical view]
ProDomiPD352676. PD352676. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetiSearch...

Publicationsi

  1. "Identification, mapping, and genomic structure of a novel X-chromosomal human gene (SMPX) encoding a small muscular protein."
    Patzak D., Zhuchenko O., Lee C.-C., Wehnert M.
    Hum. Genet. 105:506-512(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Entry informationi

Entry nameiSMPX_RAT
AccessioniPrimary (citable) accession number: Q925F0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: December 1, 2001
Last modified: January 7, 2015
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.