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Q92599

- SEPT8_HUMAN

UniProt

Q92599 - SEPT8_HUMAN

Protein

Septin-8

Gene

SEPT8

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 125 (01 Oct 2014)
      Sequence version 4 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Filament-forming cytoskeletal GTPase By similarity. May play a role in cytokinesis Potential. May play a role in platelet secretion.By similarity1 PublicationCurated

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei106 – 1061GTP; via amide nitrogenBy similarity
    Binding sitei241 – 2411GTP; via amide nitrogen and carbonyl oxygenBy similarity
    Binding sitei256 – 2561GTPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi51 – 588GTPBy similarity
    Nucleotide bindingi187 – 1959GTPBy similarity

    GO - Molecular functioni

    1. GTP binding Source: UniProtKB-KW
    2. protein binding Source: UniProtKB

    GO - Biological processi

    1. cell cycle Source: InterPro

    Keywords - Ligandi

    GTP-binding, Nucleotide-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Septin-8
    Gene namesi
    Name:SEPT8
    Synonyms:KIAA0202
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 5

    Organism-specific databases

    HGNCiHGNC:16511. SEPT8.

    Subcellular locationi

    Cytoplasm By similarity. Cytoplasmcytoskeleton By similarity
    Note: In platelets, found in areas surrounding alpha-granules.1 Publication

    GO - Cellular componenti

    1. septin complex Source: InterPro

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton

    Pathology & Biotechi

    Organism-specific databases

    PharmGKBiPA134879270.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 483482Septin-8PRO_0000173533Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylalanine1 Publication
    Modified residuei10 – 101PhosphoserineBy similarity

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ92599.
    PaxDbiQ92599.
    PRIDEiQ92599.

    PTM databases

    PhosphoSiteiQ92599.

    Expressioni

    Tissue specificityi

    Widely expressed, including in brain, heart and platelets; most abundant in aorta. Isoform 2 is expressed at low levels in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 1 and 3 are highly expressed in specific brain areas, such as occipital pole, frontal lobe, temporal lobe and putamen. Isoform 2 is highly expressed in prostate, testis and ovary. Isoform 1 and isoform 3 are expressed at low levels in prostate, testis and ovary.4 Publications

    Gene expression databases

    ArrayExpressiQ92599.
    BgeeiQ92599.
    CleanExiHS_SEPT8.
    GenevestigatoriQ92599.

    Organism-specific databases

    HPAiHPA005665.

    Interactioni

    Subunit structurei

    Septins polymerize into heterooligomeric protein complexes that form filaments, and can associate with cellular membranes, actin filaments and microtubules. GTPase activity is required for filament formation By similarity. Interacts with CDK14, SEPT4, SEPT5 and SEPT7 By similarity.By similarity

    Protein-protein interaction databases

    BioGridi116788. 12 interactions.
    IntActiQ92599. 7 interactions.
    MINTiMINT-6941937.
    STRINGi9606.ENSP00000367991.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92599.
    SMRiQ92599. Positions 21-309.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini41 – 307267Septin-type GAdd
    BLAST

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili320 – 41394Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiCOG5019.
    HOGENOMiHOG000233586.
    HOVERGENiHBG065093.
    InParanoidiQ92599.
    KOiK16939.
    OMAiLQETYET.
    OrthoDBiEOG7J9VQK.
    PhylomeDBiQ92599.
    TreeFamiTF101080.

    Family and domain databases

    Gene3Di3.40.50.300. 1 hit.
    InterProiIPR000038. Cell_div_GTP-bd.
    IPR027417. P-loop_NTPase.
    IPR016491. Septin.
    [Graphical view]
    PANTHERiPTHR18884. PTHR18884. 1 hit.
    PfamiPF00735. Septin. 1 hit.
    [Graphical view]
    PIRSFiPIRSF006698. Septin. 1 hit.
    SUPFAMiSSF52540. SSF52540. 1 hit.
    PROSITEiPS51719. G_SEPTIN. 1 hit.
    [Graphical view]

    Sequences (4)i

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    This entry describes 4 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q92599-1) [UniParc]FASTAAdd to Basket

    Also known as: KIAA0202b, SEPT8_v2

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAATDLERFS NAEPEPRSLS LGGHVGFDSL PDQLVSKSVT QGFSFNILCV    50
    GETGIGKSTL MNTLFNTTFE TEEASHHEAC VRLRPQTYDL QESNVQLKLT 100
    IVDAVGFGDQ INKDESYRPI VDYIDAQFEN YLQEELKIRR SLFDYHDTRI 150
    HVCLYFITPT GHSLKSLDLV TMKKLDSKVN IIPIIAKADT ISKSELHKFK 200
    IKIMGELVSN GVQIYQFPTD DEAVAEINAV MNAHLPFAVV GSTEEVKVGN 250
    KLVRARQYPW GVVQVENENH CDFVKLREML IRVNMEDLRE QTHSRHYELY 300
    RRCKLEEMGF QDSDGDSQPF SLQETYEAKR KEFLSELQRK EEEMRQMFVN 350
    KVKETELELK EKERELHEKF EHLKRVHQEE KRKVEEKRRE LEEETNAFNR 400
    RKAAVEALQS QALHATSQQP LRKDKDKKNR SDIGAHQPGM SLSSSKVMMT 450
    KASVEPLNCS SWWPAIQCCS CLVRDATWRE GFL 483
    Length:483
    Mass (Da):55,756
    Last modified:January 23, 2007 - v4
    Checksum:i35E1ACF95F5DBA6B
    GO
    Isoform 2 (identifier: Q92599-2) [UniParc]FASTAAdd to Basket

    Also known as: KIAA0202a, SEPT8_v1, KIAA0202c, SEPT8_v1*

    The sequence of this isoform differs from the canonical sequence as follows:
         430-483: Missing.

    Note: KIAA0202a differs from KIAA0202c at the level of the 3'-UTR.

    Show »
    Length:429
    Mass (Da):49,814
    Checksum:iB6900F134CF67474
    GO
    Isoform 3 (identifier: Q92599-3) [UniParc]FASTAAdd to Basket

    Also known as: KIAA0202d, SEPT8_v3

    The sequence of this isoform differs from the canonical sequence as follows:
         1-60: Missing.
         430-483: Missing.

    Show »
    Length:369
    Mass (Da):43,519
    Checksum:i3C85574B0124B3BA
    GO
    Isoform 4 (identifier: Q92599-4) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         429-442: NRSDIGAHQPGMSL → KASGWSSIYSVTIP
         443-483: Missing.

    Show »
    Length:442
    Mass (Da):51,178
    Checksum:i4A3D69A996FE624C
    GO

    Sequence cautioni

    The sequence AAG09407.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAH01329.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    The sequence AAO13878.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAO13879.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence AAO13880.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    The sequence BAA13193.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti116 – 1172Missing in AK057797. (PubMed:14702039)Curated
    Sequence conflicti365 – 3651E → V in AK057797. (PubMed:14702039)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 6060Missing in isoform 3. 1 PublicationVSP_009643Add
    BLAST
    Alternative sequencei429 – 44214NRSDI…PGMSL → KASGWSSIYSVTIP in isoform 4. 1 PublicationVSP_054085Add
    BLAST
    Alternative sequencei430 – 48354Missing in isoform 2 and isoform 3. 3 PublicationsVSP_009644Add
    BLAST
    Alternative sequencei443 – 48341Missing in isoform 4. 1 PublicationVSP_054086Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86957 mRNA. Translation: BAA13193.1. Different initiation.
    AF179995 mRNA. Translation: AAG09407.1. Different initiation.
    AF440761 mRNA. Translation: AAO13878.1. Different initiation.
    AF440762 mRNA. Translation: AAO13879.1. Different initiation.
    AF440763 mRNA. Translation: AAO13880.1. Different initiation.
    AK057797 mRNA. No translation available.
    AC004775 Genomic DNA. No translation available.
    CH471062 Genomic DNA. Translation: EAW62315.1.
    CH471062 Genomic DNA. Translation: EAW62317.1.
    BC001329 mRNA. Translation: AAH01329.1. Different initiation.
    CCDSiCCDS43358.1. [Q92599-1]
    CCDS43359.1. [Q92599-4]
    CCDS43360.1. [Q92599-2]
    CCDS47262.1. [Q92599-3]
    RefSeqiNP_001092281.1. NM_001098811.1. [Q92599-1]
    NP_001092282.1. NM_001098812.1. [Q92599-4]
    NP_001092283.1. NM_001098813.1. [Q92599-3]
    NP_055961.1. NM_015146.1. [Q92599-2]
    UniGeneiHs.522057.

    Genome annotation databases

    EnsembliENST00000296873; ENSP00000296873; ENSG00000164402. [Q92599-2]
    ENST00000378699; ENSP00000367971; ENSG00000164402. [Q92599-3]
    ENST00000378719; ENSP00000367991; ENSG00000164402. [Q92599-1]
    ENST00000448933; ENSP00000399840; ENSG00000164402. [Q92599-3]
    ENST00000458488; ENSP00000394766; ENSG00000164402. [Q92599-4]
    GeneIDi23176.
    KEGGihsa:23176.
    UCSCiuc003kxr.2. human. [Q92599-1]

    Polymorphism databases

    DMDMi45645200.

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D86957 mRNA. Translation: BAA13193.1 . Different initiation.
    AF179995 mRNA. Translation: AAG09407.1 . Different initiation.
    AF440761 mRNA. Translation: AAO13878.1 . Different initiation.
    AF440762 mRNA. Translation: AAO13879.1 . Different initiation.
    AF440763 mRNA. Translation: AAO13880.1 . Different initiation.
    AK057797 mRNA. No translation available.
    AC004775 Genomic DNA. No translation available.
    CH471062 Genomic DNA. Translation: EAW62315.1 .
    CH471062 Genomic DNA. Translation: EAW62317.1 .
    BC001329 mRNA. Translation: AAH01329.1 . Different initiation.
    CCDSi CCDS43358.1. [Q92599-1 ]
    CCDS43359.1. [Q92599-4 ]
    CCDS43360.1. [Q92599-2 ]
    CCDS47262.1. [Q92599-3 ]
    RefSeqi NP_001092281.1. NM_001098811.1. [Q92599-1 ]
    NP_001092282.1. NM_001098812.1. [Q92599-4 ]
    NP_001092283.1. NM_001098813.1. [Q92599-3 ]
    NP_055961.1. NM_015146.1. [Q92599-2 ]
    UniGenei Hs.522057.

    3D structure databases

    ProteinModelPortali Q92599.
    SMRi Q92599. Positions 21-309.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 116788. 12 interactions.
    IntActi Q92599. 7 interactions.
    MINTi MINT-6941937.
    STRINGi 9606.ENSP00000367991.

    PTM databases

    PhosphoSitei Q92599.

    Polymorphism databases

    DMDMi 45645200.

    Proteomic databases

    MaxQBi Q92599.
    PaxDbi Q92599.
    PRIDEi Q92599.

    Protocols and materials databases

    DNASUi 23176.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000296873 ; ENSP00000296873 ; ENSG00000164402 . [Q92599-2 ]
    ENST00000378699 ; ENSP00000367971 ; ENSG00000164402 . [Q92599-3 ]
    ENST00000378719 ; ENSP00000367991 ; ENSG00000164402 . [Q92599-1 ]
    ENST00000448933 ; ENSP00000399840 ; ENSG00000164402 . [Q92599-3 ]
    ENST00000458488 ; ENSP00000394766 ; ENSG00000164402 . [Q92599-4 ]
    GeneIDi 23176.
    KEGGi hsa:23176.
    UCSCi uc003kxr.2. human. [Q92599-1 ]

    Organism-specific databases

    CTDi 23176.
    GeneCardsi GC05M132086.
    H-InvDB HIX0032338.
    HGNCi HGNC:16511. SEPT8.
    HPAi HPA005665.
    MIMi 608418. gene.
    neXtProti NX_Q92599.
    PharmGKBi PA134879270.
    HUGEi Search...
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi COG5019.
    HOGENOMi HOG000233586.
    HOVERGENi HBG065093.
    InParanoidi Q92599.
    KOi K16939.
    OMAi LQETYET.
    OrthoDBi EOG7J9VQK.
    PhylomeDBi Q92599.
    TreeFami TF101080.

    Miscellaneous databases

    ChiTaRSi SEPT8. human.
    GeneWikii SEPT8.
    GenomeRNAii 23176.
    NextBioi 44599.
    PROi Q92599.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q92599.
    Bgeei Q92599.
    CleanExi HS_SEPT8.
    Genevestigatori Q92599.

    Family and domain databases

    Gene3Di 3.40.50.300. 1 hit.
    InterProi IPR000038. Cell_div_GTP-bd.
    IPR027417. P-loop_NTPase.
    IPR016491. Septin.
    [Graphical view ]
    PANTHERi PTHR18884. PTHR18884. 1 hit.
    Pfami PF00735. Septin. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF006698. Septin. 1 hit.
    SUPFAMi SSF52540. SSF52540. 1 hit.
    PROSITEi PS51719. G_SEPTIN. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Human septin-septin interaction: CDCrel-1 partners with KIAA0202."
      Blaeser S., Jersch K., Hainmann I., Wunderle D., Zgaga-Griesz A., Busse A., Zieger B.
      FEBS Lett. 519:169-172(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), INTERACTION WITH SEPT5, TISSUE SPECIFICITY.
    2. "Isolation of new splice isoforms, characterization and expression analysis of the human septin SEPT8 (KIAA0202)."
      Blaeser S., Jersch K., Hainmann I., Zieger W., Wunderle D., Busse A., Zieger B.
      Gene 312:313-320(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3), ALTERNATIVE SPLICING, INTERACTION WITH SEPT5, TISSUE SPECIFICITY.
    3. "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
      Nagase T., Seki N., Ishikawa K., Ohira M., Kawarabayasi Y., Ohara O., Tanaka A., Kotani H., Miyajima N., Nomura N.
      DNA Res. 3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
      Tissue: Bone marrow.
    4. "Identification of 40 genes on a 1-Mb contig around the IL-4 cytokine family gene cluster on mouse chromosome 11."
      Wenderfer S.E., Slack J.P., McCluskey T.S., Monaco J.J.
      Genomics 63:354-373(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    5. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
      , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
      Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4).
    6. "The DNA sequence and comparative analysis of human chromosome 5."
      Schmutz J., Martin J., Terry A., Couronne O., Grimwood J., Lowry S., Gordon L.A., Scott D., Xie G., Huang W., Hellsten U., Tran-Gyamfi M., She X., Prabhakar S., Aerts A., Altherr M., Bajorek E., Black S.
      , Branscomb E., Caoile C., Challacombe J.F., Chan Y.M., Denys M., Detter J.C., Escobar J., Flowers D., Fotopulos D., Glavina T., Gomez M., Gonzales E., Goodstein D., Grigoriev I., Groza M., Hammon N., Hawkins T., Haydu L., Israni S., Jett J., Kadner K., Kimball H., Kobayashi A., Lopez F., Lou Y., Martinez D., Medina C., Morgan J., Nandkeshwar R., Noonan J.P., Pitluck S., Pollard M., Predki P., Priest J., Ramirez L., Retterer J., Rodriguez A., Rogers S., Salamov A., Salazar A., Thayer N., Tice H., Tsai M., Ustaszewska A., Vo N., Wheeler J., Wu K., Yang J., Dickson M., Cheng J.-F., Eichler E.E., Olsen A., Pennacchio L.A., Rokhsar D.S., Richardson P., Lucas S.M., Myers R.M., Rubin E.M.
      Nature 431:268-274(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 122-483 (ISOFORMS 2/3).
      Tissue: Cervix.
    9. Cited for: IDENTIFICATION OF INITIATOR METHIONINE.
    10. "KIAA0202, a human septin family member, interacting with hPFTAIRE1."
      Yang T., Gao Y.K., Chen J.Y.
      Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao 34:520-525(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CDK14.
    11. Cited for: FUNCTION, INTERACTION WITH SEPT4, SUBCELLULAR LOCATION, TISSUE SPECIFICITY.
    12. "Expression profiling the human septin gene family."
      Hall P.A., Jung K., Hillan K.J., Russell S.E.H.
      J. Pathol. 206:269-278(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY.
    13. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    14. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS], CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS].

    Entry informationi

    Entry nameiSEPT8_HUMAN
    AccessioniPrimary (citable) accession number: Q92599
    Secondary accession number(s): A6NC65
    , A6NKP6, F6W7K9, Q8IX36, Q8IX37, Q9BVB3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 1, 2000
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 125 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 5
      Human chromosome 5: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3