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Q92570

- NR4A3_HUMAN

UniProt

Q92570 - NR4A3_HUMAN

Protein

Nuclear receptor subfamily 4 group A member 3

Gene

NR4A3

Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 148 (01 Oct 2014)
      Sequence version 3 (21 Mar 2006)
      Previous versions | rss
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    Functioni

    Binds to the B1A response-element.

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    DNA bindingi289 – 36476Nuclear receptorPROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri292 – 31221NR C4-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri328 – 35225NR C4-typePROSITE-ProRule annotationAdd
    BLAST

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB
    2. RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription Source: Ensembl
    3. sequence-specific DNA binding Source: Ensembl
    4. steroid hormone receptor activity Source: ProtInc
    5. thyroid hormone receptor activity Source: ProtInc
    6. zinc ion binding Source: InterPro

    GO - Biological processi

    1. adult behavior Source: Ensembl
    2. axon guidance Source: Ensembl
    3. gene expression Source: Reactome
    4. hippocampus development Source: Ensembl
    5. intracellular receptor signaling pathway Source: GOC
    6. mesoderm formation Source: Ensembl
    7. negative regulation of neuron apoptotic process Source: Ensembl
    8. neuromuscular process controlling balance Source: Ensembl
    9. organ regeneration Source: Ensembl
    10. positive regulation of cell cycle Source: Ensembl
    11. positive regulation of leukocyte apoptotic process Source: Ensembl
    12. response to hydrogen peroxide Source: Ensembl
    13. response to peptide hormone Source: Ensembl
    14. semicircular canal morphogenesis Source: Ensembl
    15. transcription initiation from RNA polymerase II promoter Source: Reactome
    16. vestibular reflex Source: Ensembl

    Keywords - Molecular functioni

    Receptor

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding, Metal-binding, Zinc

    Enzyme and pathway databases

    ReactomeiREACT_15525. Nuclear Receptor transcription pathway.
    SignaLinkiQ92570.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nuclear receptor subfamily 4 group A member 3
    Alternative name(s):
    Mitogen-induced nuclear orphan receptor
    Neuron-derived orphan receptor 1
    Nuclear hormone receptor NOR-1
    Gene namesi
    Name:NR4A3
    Synonyms:CHN, CSMF, MINOR, NOR1, TEC
    OrganismiHomo sapiens (Human)
    Taxonomic identifieri9606 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
    ProteomesiUP000005640: Chromosome 9

    Organism-specific databases

    HGNCiHGNC:7982. NR4A3.

    Subcellular locationi

    Nucleus PROSITE-ProRule annotation

    GO - Cellular componenti

    1. nucleoplasm Source: Reactome
    2. nucleus Source: UniProtKB
    3. transcription factor complex Source: Ensembl

    Keywords - Cellular componenti

    Nucleus

    Pathology & Biotechi

    Involvement in diseasei

    Ewing sarcoma (ES) [MIM:612219]: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors.
    Note: The gene represented in this entry is involved in disease pathogenesis. A chromosomal aberration involving NR4A3 is found in patients with Erwing sarcoma. Translocation t(9;22)(q22-31;q11-12) with EWSR1.
    A chromosomal aberration involving NR4A3 is a cause of a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with TAF2N.

    Keywords - Diseasei

    Proto-oncogene

    Organism-specific databases

    MIMi600542. gene+phenotype.
    612219. phenotype.
    Orphaneti209916. Extraskeletal myxoid chondrosarcoma.
    PharmGKBiPA31763.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 626626Nuclear receptor subfamily 4 group A member 3PRO_0000053722Add
    BLAST

    Proteomic databases

    MaxQBiQ92570.
    PaxDbiQ92570.
    PRIDEiQ92570.

    PTM databases

    PhosphoSiteiQ92570.

    Expressioni

    Tissue specificityi

    Isoform alpha is highly expressed in skeletal muscle. Isoform beta is highly expressed in skeletal muscle and low expressed in fetal brain and placenta.

    Gene expression databases

    BgeeiQ92570.
    CleanExiHS_NR4A3.
    HS_TEC.
    GenevestigatoriQ92570.

    Organism-specific databases

    HPAiHPA043360.

    Interactioni

    Protein-protein interaction databases

    BioGridi113713. 4 interactions.

    Structurei

    3D structure databases

    ProteinModelPortaliQ92570.
    SMRiQ92570. Positions 290-626.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni440 – 49051Ligand-bindingSequence AnalysisAdd
    BLAST

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi95 – 10814Poly-HisAdd
    BLAST
    Compositional biasi282 – 2876Poly-Ser

    Sequence similaritiesi

    Contains 1 nuclear receptor DNA-binding domain.PROSITE-ProRule annotation

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri292 – 31221NR C4-typePROSITE-ProRule annotationAdd
    BLAST
    Zinc fingeri328 – 35225NR C4-typePROSITE-ProRule annotationAdd
    BLAST

    Keywords - Domaini

    Zinc-finger

    Phylogenomic databases

    eggNOGiNOG245120.
    HOVERGENiHBG052663.
    InParanoidiQ92570.
    KOiK08559.
    OMAiCMMNALV.
    OrthoDBiEOG75XGKJ.
    PhylomeDBiQ92570.
    TreeFamiTF315430.

    Family and domain databases

    Gene3Di1.10.565.10. 1 hit.
    3.30.50.10. 1 hit.
    InterProiIPR003072. NOR1_rcpt.
    IPR003070. Nuc_orph_rcpt.
    IPR008946. Nucl_hormone_rcpt_ligand-bd.
    IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
    IPR001723. Str_hrmn_rcpt.
    IPR001628. Znf_hrmn_rcpt.
    IPR013088. Znf_NHR/GATA.
    [Graphical view]
    PfamiPF00104. Hormone_recep. 1 hit.
    PF00105. zf-C4. 1 hit.
    [Graphical view]
    PRINTSiPR01286. NORNUCRECPTR.
    PR01284. NUCLEARECPTR.
    PR00398. STRDHORMONER.
    PR00047. STROIDFINGER.
    SMARTiSM00430. HOLI. 1 hit.
    SM00399. ZnF_C4. 1 hit.
    [Graphical view]
    SUPFAMiSSF48508. SSF48508. 1 hit.
    PROSITEiPS00031. NUCLEAR_REC_DBD_1. 1 hit.
    PS51030. NUCLEAR_REC_DBD_2. 1 hit.
    [Graphical view]

    Sequences (3)i

    Sequence statusi: Complete.

    This entry describes 3 isoformsi produced by alternative splicing. Align

    Isoform Alpha (identifier: Q92570-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPCVQAQYSP SPPGSSYAAQ TYSSEYTTEI MNPDYTKLTM DLGSTEITAT    50
    ATTSLPSIST FVEGYSSNYE LKPSCVYQMQ RPLIKVEEGR APSYHHHHHH 100
    HHHHHHHHQQ QHQQPSIPPA SSPEDEVLPS TSMYFKQSPP STPTTPAFPP 150
    QAGALWDEAL PSAPGCIAPG PLLDPPMKAV PTVAGARFPL FHFKPSPPHP 200
    PAPSPAGGHH LGYDPTAAAA LSLPLGAAAA AGSQAAALES HPYGLPLAKR 250
    AAPLAFPPLG LTPSPTASSL LGESPSLPSP PSRSSSSGEG TCAVCGDNAA 300
    CQHYGVRTCE GCKGFFKRTV QKNAKYVCLA NKNCPVDKRR RNRCQYCRFQ 350
    KCLSVGMVKE VVRTDSLKGR RGRLPSKPKS PLQQEPSQPS PPSPPICMMN 400
    ALVRALTDST PRDLDYSRYC PTDQAAAGTD AEHVQQFYNL LTASIDVSRS 450
    WAEKIPGFTD LPKEDQTLLI ESAFLELFVL RLSIRSNTAE DKFVFCNGLV 500
    LHRLQCLRGF GEWLDSIKDF SLNLQSLNLD IQALACLSAL SMITERHGLK 550
    EPKRVEELCN KITSSLKDHQ SKGQALEPTE SKVLGALVEL RKICTLGLQR 600
    IFYLKLEDLV SPPSIIDKLF LDTLPF 626
    Length:626
    Mass (Da):68,230
    Last modified:March 21, 2006 - v3
    Checksum:iFB4A1AB7667D96F6
    GO
    Isoform Beta (identifier: Q92570-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         419-443: YCPTDQAAAGTDAEHVQQFYNLLTA → VSFMISCFQMNDQGLYLWLLVIRVD
         444-626: Missing.

    Show »
    Length:443
    Mass (Da):47,822
    Checksum:i42E97CAE053BA5EF
    GO
    Isoform 3 (identifier: Q92570-3) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-1: M → MHDSIRFGNVDM

    Note: No experimental confirmation available.

    Show »
    Length:637
    Mass (Da):69,502
    Checksum:i584261AA3DAA3AD5
    GO

    Sequence cautioni

    The sequence AAB02581.1 differs from that shown. Reason: Frameshift at positions 4 and 20.
    The sequence AAB36006.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti240 – 2401S → G(PubMed:8809112)Curated
    Sequence conflicti240 – 2401S → G(PubMed:8614405)Curated
    Sequence conflicti454 – 4541K → R in BAA11419. (PubMed:8809112)Curated
    Sequence conflicti579 – 5791T → N in BAA11419. (PubMed:8809112)Curated
    Sequence conflicti585 – 5851G → V in BAA11419. (PubMed:8809112)Curated

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 11M → MHDSIRFGNVDM in isoform 3. CuratedVSP_037877
    Alternative sequencei419 – 44325YCPTD…NLLTA → VSFMISCFQMNDQGLYLWLL VIRVD in isoform Beta. 2 PublicationsVSP_003712Add
    BLAST
    Alternative sequencei444 – 626183Missing in isoform Beta. 2 PublicationsVSP_003713Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78579 mRNA. Translation: BAA11419.1.
    U12767 mRNA. Translation: AAB02581.1. Frameshift.
    S81243 mRNA. Translation: AAB36006.1. Different initiation.
    X89894 mRNA. Translation: CAA61984.1.
    AL359710 Genomic DNA. Translation: CAI95139.1.
    AL359710, AL358937 Genomic DNA. Translation: CAI95138.1.
    AL358937, AL359710 Genomic DNA. Translation: CAI95320.1.
    AL359710, AL358937 Genomic DNA. Translation: CAM16648.1.
    AL358937, AL359710 Genomic DNA. Translation: CAM22558.1.
    CH471105 Genomic DNA. Translation: EAW58915.1.
    D85241 mRNA. Translation: BAA28608.1.
    D85242 mRNA. Translation: BAA31221.1.
    CCDSiCCDS6742.1. [Q92570-3]
    CCDS6743.1. [Q92570-1]
    CCDS6744.1. [Q92570-2]
    PIRiS71930.
    RefSeqiNP_008912.2. NM_006981.3. [Q92570-1]
    NP_775291.1. NM_173199.2. [Q92570-2]
    NP_775292.1. NM_173200.2. [Q92570-3]
    UniGeneiHs.279522.

    Genome annotation databases

    EnsembliENST00000330847; ENSP00000333122; ENSG00000119508. [Q92570-3]
    ENST00000338488; ENSP00000340301; ENSG00000119508. [Q92570-2]
    ENST00000395097; ENSP00000378531; ENSG00000119508. [Q92570-1]
    GeneIDi8013.
    KEGGihsa:8013.
    UCSCiuc004bae.3. human. [Q92570-2]
    uc004baf.1. human. [Q92570-1]
    uc022bky.1. human. [Q92570-3]

    Polymorphism databases

    DMDMi90110039.

    Keywords - Coding sequence diversityi

    Alternative splicing, Chromosomal rearrangement

    Cross-referencesi

    Web resourcesi

    Atlas of Genetics and Cytogenetics in Oncology and Haematology

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D78579 mRNA. Translation: BAA11419.1 .
    U12767 mRNA. Translation: AAB02581.1 . Frameshift.
    S81243 mRNA. Translation: AAB36006.1 . Different initiation.
    X89894 mRNA. Translation: CAA61984.1 .
    AL359710 Genomic DNA. Translation: CAI95139.1 .
    AL359710 , AL358937 Genomic DNA. Translation: CAI95138.1 .
    AL358937 , AL359710 Genomic DNA. Translation: CAI95320.1 .
    AL359710 , AL358937 Genomic DNA. Translation: CAM16648.1 .
    AL358937 , AL359710 Genomic DNA. Translation: CAM22558.1 .
    CH471105 Genomic DNA. Translation: EAW58915.1 .
    D85241 mRNA. Translation: BAA28608.1 .
    D85242 mRNA. Translation: BAA31221.1 .
    CCDSi CCDS6742.1. [Q92570-3 ]
    CCDS6743.1. [Q92570-1 ]
    CCDS6744.1. [Q92570-2 ]
    PIRi S71930.
    RefSeqi NP_008912.2. NM_006981.3. [Q92570-1 ]
    NP_775291.1. NM_173199.2. [Q92570-2 ]
    NP_775292.1. NM_173200.2. [Q92570-3 ]
    UniGenei Hs.279522.

    3D structure databases

    ProteinModelPortali Q92570.
    SMRi Q92570. Positions 290-626.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 113713. 4 interactions.

    Chemistry

    ChEMBLi CHEMBL1961792.

    PTM databases

    PhosphoSitei Q92570.

    Polymorphism databases

    DMDMi 90110039.

    Proteomic databases

    MaxQBi Q92570.
    PaxDbi Q92570.
    PRIDEi Q92570.

    Protocols and materials databases

    DNASUi 8013.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENST00000330847 ; ENSP00000333122 ; ENSG00000119508 . [Q92570-3 ]
    ENST00000338488 ; ENSP00000340301 ; ENSG00000119508 . [Q92570-2 ]
    ENST00000395097 ; ENSP00000378531 ; ENSG00000119508 . [Q92570-1 ]
    GeneIDi 8013.
    KEGGi hsa:8013.
    UCSCi uc004bae.3. human. [Q92570-2 ]
    uc004baf.1. human. [Q92570-1 ]
    uc022bky.1. human. [Q92570-3 ]

    Organism-specific databases

    CTDi 8013.
    GeneCardsi GC09P102584.
    HGNCi HGNC:7982. NR4A3.
    HPAi HPA043360.
    MIMi 600542. gene+phenotype.
    612219. phenotype.
    neXtProti NX_Q92570.
    Orphaneti 209916. Extraskeletal myxoid chondrosarcoma.
    PharmGKBi PA31763.
    GenAtlasi Search...

    Phylogenomic databases

    eggNOGi NOG245120.
    HOVERGENi HBG052663.
    InParanoidi Q92570.
    KOi K08559.
    OMAi CMMNALV.
    OrthoDBi EOG75XGKJ.
    PhylomeDBi Q92570.
    TreeFami TF315430.

    Enzyme and pathway databases

    Reactomei REACT_15525. Nuclear Receptor transcription pathway.
    SignaLinki Q92570.

    Miscellaneous databases

    ChiTaRSi NR4A3. human.
    GeneWikii Neuron-derived_orphan_receptor_1.
    GenomeRNAii 8013.
    NextBioi 30567.
    PROi Q92570.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q92570.
    CleanExi HS_NR4A3.
    HS_TEC.
    Genevestigatori Q92570.

    Family and domain databases

    Gene3Di 1.10.565.10. 1 hit.
    3.30.50.10. 1 hit.
    InterProi IPR003072. NOR1_rcpt.
    IPR003070. Nuc_orph_rcpt.
    IPR008946. Nucl_hormone_rcpt_ligand-bd.
    IPR000536. Nucl_hrmn_rcpt_lig-bd_core.
    IPR001723. Str_hrmn_rcpt.
    IPR001628. Znf_hrmn_rcpt.
    IPR013088. Znf_NHR/GATA.
    [Graphical view ]
    Pfami PF00104. Hormone_recep. 1 hit.
    PF00105. zf-C4. 1 hit.
    [Graphical view ]
    PRINTSi PR01286. NORNUCRECPTR.
    PR01284. NUCLEARECPTR.
    PR00398. STRDHORMONER.
    PR00047. STROIDFINGER.
    SMARTi SM00430. HOLI. 1 hit.
    SM00399. ZnF_C4. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48508. SSF48508. 1 hit.
    PROSITEi PS00031. NUCLEAR_REC_DBD_1. 1 hit.
    PS51030. NUCLEAR_REC_DBD_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Structure, mapping and expression of a human NOR-1 gene, the third member of the Nur77/NGFI-B family."
      Ohkura N., Ito M., Tsukada T., Sasaki K., Yamaguchi K., Miki K.
      Biochim. Biophys. Acta 1308:205-214(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA).
      Tissue: Fetal brain.
    2. "The isolation and characterization of MINOR, a novel mitogen-inducible nuclear orphan receptor."
      Hedvat C.V., Irving S.G.
      Mol. Endocrinol. 9:1692-1700(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA).
      Tissue: Peripheral blood.
    3. "Fusion of the EWS gene to CHN, a member of the steroid/thyroid receptor gene superfamily, in a human myxoid chondrosarcoma."
      Clark J., Benjamin H., Gill S., Sidhar S., Goodwin G., Crew J., Gusterson B.A., Shipley J., Cooper C.S.
      Oncogene 12:229-235(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM ALPHA).
      Tissue: Fetal brain.
    4. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM BETA), CHROMOSOMAL TRANSLOCATION WITH EWS.
      Tissue: Fetal heart.
    5. "DNA sequence and analysis of human chromosome 9."
      Humphray S.J., Oliver K., Hunt A.R., Plumb R.W., Loveland J.E., Howe K.L., Andrews T.D., Searle S., Hunt S.E., Scott C.E., Jones M.C., Ainscough R., Almeida J.P., Ambrose K.D., Ashwell R.I.S., Babbage A.K., Babbage S., Bagguley C.L.
      , Bailey J., Banerjee R., Barker D.J., Barlow K.F., Bates K., Beasley H., Beasley O., Bird C.P., Bray-Allen S., Brown A.J., Brown J.Y., Burford D., Burrill W., Burton J., Carder C., Carter N.P., Chapman J.C., Chen Y., Clarke G., Clark S.Y., Clee C.M., Clegg S., Collier R.E., Corby N., Crosier M., Cummings A.T., Davies J., Dhami P., Dunn M., Dutta I., Dyer L.W., Earthrowl M.E., Faulkner L., Fleming C.J., Frankish A., Frankland J.A., French L., Fricker D.G., Garner P., Garnett J., Ghori J., Gilbert J.G.R., Glison C., Grafham D.V., Gribble S., Griffiths C., Griffiths-Jones S., Grocock R., Guy J., Hall R.E., Hammond S., Harley J.L., Harrison E.S.I., Hart E.A., Heath P.D., Henderson C.D., Hopkins B.L., Howard P.J., Howden P.J., Huckle E., Johnson C., Johnson D., Joy A.A., Kay M., Keenan S., Kershaw J.K., Kimberley A.M., King A., Knights A., Laird G.K., Langford C., Lawlor S., Leongamornlert D.A., Leversha M., Lloyd C., Lloyd D.M., Lovell J., Martin S., Mashreghi-Mohammadi M., Matthews L., McLaren S., McLay K.E., McMurray A., Milne S., Nickerson T., Nisbett J., Nordsiek G., Pearce A.V., Peck A.I., Porter K.M., Pandian R., Pelan S., Phillimore B., Povey S., Ramsey Y., Rand V., Scharfe M., Sehra H.K., Shownkeen R., Sims S.K., Skuce C.D., Smith M., Steward C.A., Swarbreck D., Sycamore N., Tester J., Thorpe A., Tracey A., Tromans A., Thomas D.W., Wall M., Wallis J.M., West A.P., Whitehead S.L., Willey D.L., Williams S.A., Wilming L., Wray P.W., Young L., Ashurst J.L., Coulson A., Blocker H., Durbin R.M., Sulston J.E., Hubbard T., Jackson M.J., Bentley D.R., Beck S., Rogers J., Dunham I.
      Nature 429:369-374(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    6. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], ALTERNATIVE SPLICING (ISOFORM 3).
    7. "Alternative splicing generates isoforms of human neuron-derived orphan receptor-1 (NOR-1) mRNA."
      Ohkura N., Ito M., Tsukada T., Sasaki K., Yamaguchi K., Miki K.
      Gene 211:79-85(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-69 AND 301-443 (ISOFORM BETA), ALTERNATIVE SPLICING.
      Tissue: Skeletal muscle.

    Entry informationi

    Entry nameiNR4A3_HUMAN
    AccessioniPrimary (citable) accession number: Q92570
    Secondary accession number(s): A2A3I7
    , Q12935, Q14979, Q16420, Q4VXA8, Q4VXA9, Q9UEK2, Q9UEK3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1997
    Last sequence update: March 21, 2006
    Last modified: October 1, 2014
    This is version 148 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program
    DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Human chromosome 9
      Human chromosome 9: entries, gene names and cross-references to MIM
    2. MIM cross-references
      Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3