Q92523 (CPT1B_HUMAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Carnitine O-palmitoyltransferase 1, muscle isoform
Short name=CPT1-M
EC=2.3.1.21

Alternative name(s):
Carnitine O-palmitoyltransferase I, muscle isoform
Short name=CPT I
Short name=CPTI-M
Carnitine palmitoyltransferase 1B
Carnitine palmitoyltransferase I-like protein

Gene names

Name:	CPT1B
Synonyms:	KIAA1670

Organism

Homo sapiens (Human) [Reference proteome]

Taxonomic identifier

9606 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Primates › Haplorrhini › Simiiformes › Catarrhini › Hominoidea › Hominidae › Homininae › Homo

Protein attributes

Sequence length	772 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Catalytic activity	Palmitoyl-CoA + L-carnitine = CoA + L-palmitoylcarnitine.
Pathway	Lipid metabolism; fatty acid beta-oxidation.
Subcellular location	Mitochondrion outer membrane; Multi-pass membrane protein.
Tissue specificity	Strong expression in heart and skeletal muscle. No expression in liver and kidney.
Miscellaneous	This protein is produced by a bicistronic gene which also produces the CHKB protein from a non-overlapping reading frame.
Sequence similarities	Belongs to the carnitine/choline acetyltransferase family.
Sequence caution	The sequence BAB33340.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Biological process	Fatty acid metabolism Lipid metabolism Transport
Cellular component	Membrane Mitochondrion Mitochondrion outer membrane
Coding sequence diversity	Alternative splicing Polymorphism
Domain	Transmembrane Transmembrane helix
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	carnitine shuttle Traceable author statement. Source: Reactome fatty acid beta-oxidation Traceable author statement PubMed 10408760. Source: ProtInc
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW mitochondrial outer membrane Traceable author statement. Source: Reactome
Molecular_function	carnitine O-palmitoyltransferase activity Traceable author statement PubMed 10408760. Source: ProtInc
Complete GO annotation...

Alternative products

This entry describes 4 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q92523-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q92523-2)

The sequence of this isoform differs from the canonical sequence as follows:
     581-581: D → G
     582-772: Missing.

Isoform 3 (identifier: Q92523-3)

The sequence of this isoform differs from the canonical sequence as follows:
     154-187: Missing.

Note: No experimental confirmation available.

Isoform 4 (identifier: Q92523-4)

The sequence of this isoform differs from the canonical sequence as follows:
     355-435: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 772	772	Carnitine O-palmitoyltransferase 1, muscle isoform		PRO_0000210162
Regions
	Topological domain	1 – 47	47	Cytoplasmic Potential
	Transmembrane	48 – 73	26	Helical; Potential
	Topological domain	74 – 102	29	Mitochondrial intermembrane Potential
	Transmembrane	103 – 122	20	Helical; Potential
	Topological domain	123 – 772	650	Cytoplasmic Potential
	Region	555 – 567	13	Coenzyme A binding By similarity
Sites
	Active site	473	1	Proton acceptor By similarity
	Binding site	589	1	Carnitine By similarity
	Binding site	602	1	Carnitine By similarity
Natural variations
	Alternative sequence	154 – 187	34	Missing in isoform 3.		VSP_043184
	Alternative sequence	355 – 435	81	Missing in isoform 4.		VSP_044451
	Alternative sequence	581	1	D → G in isoform 2.		VSP_034246
	Alternative sequence	582 – 772	191	Missing in isoform 2.		VSP_034247
	Natural variant	66	1	I → V. Corresponds to variant rs3213445 [ dbSNP | Ensembl ].		VAR_020029
	Natural variant	320	1	G → D. Corresponds to variant rs2269383 [ dbSNP | Ensembl ].		VAR_021854
	Natural variant	427	1	S → C. Corresponds to variant rs8142477 [ dbSNP | Ensembl ].		VAR_024188
	Natural variant	531	1	E → K. Ref.6 Ref.7 Corresponds to variant rs470117 [ dbSNP | Ensembl ].		VAR_011739
	Natural variant	664	1	S → Y. Corresponds to variant rs1804702 [ dbSNP | Ensembl ].		VAR_011740
Experimental info
	Sequence conflict	75	1	C → S in BAH13024. Ref.7

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified November 1, 1997. Version 2. Checksum: F7E3ED40643DFC81	FASTA	772	87,801
	10 20 30 40 50 60 MAEAHQAVAF QFTVTPDGVD FRLSREALKH VYLSGINSWK KRLIRIKNGI LRGVYPGSPT 70 80 90 100 110 120 SWLVVIMATV GSSFCNVDIS LGLVSCIQRC LPQGCGPYQT PQTRALLSMA IFSTGVWVTG 130 140 150 160 170 180 IFFFRQTLKL LLCYHGWMFE MHGKTSNLTR IWAMCIRLLS SRHPMLYSFQ TSLPKLPVPR 190 200 210 220 230 240 VSATIQRYLE SVRPLLDDEE YYRMELLAKE FQDKTAPRLQ KYLVLKSWWA SNYVSDWWEE 250 260 270 280 290 300 YIYLRGRSPL MVNSNYYVMD LVLIKNTDVQ AARLGNIIHA MIMYRRKLDR EEIKPVMALG 310 320 330 340 350 360 IVPMCSYQME RMFNTTRIPG KDTDVLQHLS DSRHVAVYHK GRFFKLWLYE GARLLKPQDL 370 380 390 400 410 420 EMQFQRILDD PSPPQPGEEK LAALTAGGRV EWAQARQAFF SSGKNKAALE AIERAAFFVA 430 440 450 460 470 480 LDEESYSYDP EDEASLSLYG KALLHGNCYN RWFDKSFTLI SFKNGQLGLN AEHAWADAPI 490 500 510 520 530 540 IGHLWEFVLG TDSFHLGYTE TGHCLGKPNP ALAPPTRLQW DIPKQCQAVI ESSYQVAKAL 550 560 570 580 590 600 ADDVELYCFQ FLPFGKGLIK KCRTSPDAFV QIALQLAHFR DRGKFCLTYE ASMTRMFREG 610 620 630 640 650 660 RTETVRSCTS ESTAFVQAMM EGSHTKADLR DLFQKAAKKH QNMYRLAMTG AGIDRHLFCL 670 680 690 700 710 720 YLVSKYLGVS SPFLAEVLSE PWRLSTSQIP QSQIRMFDPE QHPNHLGAGG GFGPVADDGY 730 740 750 760 770 GVSYMIAGEN TIFFHISSKF SSSETNAQRF GNHIRKALLD IADLFQVPKA YS
	Isoform 2 [UniParc]. Checksum: 3814222A5BDBF724	FASTA	581	66,384
	10 20 30 40 50 60 MAEAHQAVAF QFTVTPDGVD FRLSREALKH VYLSGINSWK KRLIRIKNGI LRGVYPGSPT 70 80 90 100 110 120 SWLVVIMATV GSSFCNVDIS LGLVSCIQRC LPQGCGPYQT PQTRALLSMA IFSTGVWVTG 130 140 150 160 170 180 IFFFRQTLKL LLCYHGWMFE MHGKTSNLTR IWAMCIRLLS SRHPMLYSFQ TSLPKLPVPR 190 200 210 220 230 240 VSATIQRYLE SVRPLLDDEE YYRMELLAKE FQDKTAPRLQ KYLVLKSWWA SNYVSDWWEE 250 260 270 280 290 300 YIYLRGRSPL MVNSNYYVMD LVLIKNTDVQ AARLGNIIHA MIMYRRKLDR EEIKPVMALG 310 320 330 340 350 360 IVPMCSYQME RMFNTTRIPG KDTDVLQHLS DSRHVAVYHK GRFFKLWLYE GARLLKPQDL 370 380 390 400 410 420 EMQFQRILDD PSPPQPGEEK LAALTAGGRV EWAQARQAFF SSGKNKAALE AIERAAFFVA 430 440 450 460 470 480 LDEESYSYDP EDEASLSLYG KALLHGNCYN RWFDKSFTLI SFKNGQLGLN AEHAWADAPI 490 500 510 520 530 540 IGHLWEFVLG TDSFHLGYTE TGHCLGKPNP ALAPPTRLQW DIPKQCQAVI ESSYQVAKAL 550 560 570 580 ADDVELYCFQ FLPFGKGLIK KCRTSPDAFV QIALQLAHFR G
	Isoform 3 [UniParc]. Checksum: 24F7EAC9FFEE3D31	FASTA	738	83,891
	10 20 30 40 50 60 MAEAHQAVAF QFTVTPDGVD FRLSREALKH VYLSGINSWK KRLIRIKNGI LRGVYPGSPT 70 80 90 100 110 120 SWLVVIMATV GSSFCNVDIS LGLVSCIQRC LPQGCGPYQT PQTRALLSMA IFSTGVWVTG 130 140 150 160 170 180 IFFFRQTLKL LLCYHGWMFE MHGKTSNLTR IWAYLESVRP LLDDEEYYRM ELLAKEFQDK 190 200 210 220 230 240 TAPRLQKYLV LKSWWASNYV SDWWEEYIYL RGRSPLMVNS NYYVMDLVLI KNTDVQAARL 250 260 270 280 290 300 GNIIHAMIMY RRKLDREEIK PVMALGIVPM CSYQMERMFN TTRIPGKDTD VLQHLSDSRH 310 320 330 340 350 360 VAVYHKGRFF KLWLYEGARL LKPQDLEMQF QRILDDPSPP QPGEEKLAAL TAGGRVEWAQ 370 380 390 400 410 420 ARQAFFSSGK NKAALEAIER AAFFVALDEE SYSYDPEDEA SLSLYGKALL HGNCYNRWFD 430 440 450 460 470 480 KSFTLISFKN GQLGLNAEHA WADAPIIGHL WEFVLGTDSF HLGYTETGHC LGKPNPALAP 490 500 510 520 530 540 PTRLQWDIPK QCQAVIESSY QVAKALADDV ELYCFQFLPF GKGLIKKCRT SPDAFVQIAL 550 560 570 580 590 600 QLAHFRDRGK FCLTYEASMT RMFREGRTET VRSCTSESTA FVQAMMEGSH TKADLRDLFQ 610 620 630 640 650 660 KAAKKHQNMY RLAMTGAGID RHLFCLYLVS KYLGVSSPFL AEVLSEPWRL STSQIPQSQI 670 680 690 700 710 720 RMFDPEQHPN HLGAGGGFGP VADDGYGVSY MIAGENTIFF HISSKFSSSE TNAQRFGNHI 730 RKALLDIADL FQVPKAYS
	Isoform 4 [UniParc]. Checksum: ED1E1029F325C8F4	FASTA	691	78,844
	10 20 30 40 50 60 MAEAHQAVAF QFTVTPDGVD FRLSREALKH VYLSGINSWK KRLIRIKNGI LRGVYPGSPT 70 80 90 100 110 120 SWLVVIMATV GSSFCNVDIS LGLVSCIQRC LPQGCGPYQT PQTRALLSMA IFSTGVWVTG 130 140 150 160 170 180 IFFFRQTLKL LLCYHGWMFE MHGKTSNLTR IWAMCIRLLS SRHPMLYSFQ TSLPKLPVPR 190 200 210 220 230 240 VSATIQRYLE SVRPLLDDEE YYRMELLAKE FQDKTAPRLQ KYLVLKSWWA SNYVSDWWEE 250 260 270 280 290 300 YIYLRGRSPL MVNSNYYVMD LVLIKNTDVQ AARLGNIIHA MIMYRRKLDR EEIKPVMALG 310 320 330 340 350 360 IVPMCSYQME RMFNTTRIPG KDTDVLQHLS DSRHVAVYHK GRFFKLWLYE GARLLSLYGK 370 380 390 400 410 420 ALLHGNCYNR WFDKSFTLIS FKNGQLGLNA EHAWADAPII GHLWEFVLGT DSFHLGYTET 430 440 450 460 470 480 GHCLGKPNPA LAPPTRLQWD IPKQCQAVIE SSYQVAKALA DDVELYCFQF LPFGKGLIKK 490 500 510 520 530 540 CRTSPDAFVQ IALQLAHFRD RGKFCLTYEA SMTRMFREGR TETVRSCTSE STAFVQAMME 550 560 570 580 590 600 GSHTKADLRD LFQKAAKKHQ NMYRLAMTGA GIDRHLFCLY LVSKYLGVSS PFLAEVLSEP 610 620 630 640 650 660 WRLSTSQIPQ SQIRMFDPEQ HPNHLGAGGG FGPVADDGYG VSYMIAGENT IFFHISSKFS 670 680 690 SSETNAQRFG NHIRKALLDI ADLFQVPKAY S

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Isolation and characterization of cDNA and genomic clones encoding human muscle type carnitine palmitoyltransferase I." Yamazaki N., Shinohara Y., Shima A., Yamanaka Y., Terada H. Biochim. Biophys. Acta 1307:157-161(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Heart.
[2]	"Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I." Zhu H., Shi J., de Vries Y., Arvidson D.N., Cregg J.M., Woldegiorgis G. Arch. Biochem. Biophys. 347:53-61(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[3]	"Fine chromosome mapping of the genes for human liver and muscle carnitine palmitoyltransferase I (CPT1A and CPT1B)." Britton C.H., Mackey D.W., Esser V., Foster D.W., Burns D.K., Yarnall D.P., Froguel P., McGarry J.D. Genomics 40:209-211(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Heart.
[4]	"Localization and intron usage analysis of the human CPT1B gene for muscle type carnitine palmitoyltransferase I." van der Leij F.R., Takens J., van der Veen A.Y., Terpstra P., Kuipers J.R.G. Biochim. Biophys. Acta 1352:123-128(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1). Tissue: Skeletal muscle.
[5]	"Structural features of the gene encoding human muscle type carnitine palmitoyltransferase I." Yamazaki N., Yamanaka Y., Hashimoto Y., Shinohara Y., Shima A., Terada H. FEBS Lett. 409:401-406(1997) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 1).
[6]	"Identification of novel transcribed sequences on human chromosome 22 by expressed sequence tag mapping." Hirosawa M., Nagase T., Murahashi Y., Kikuno R., Ohara O. DNA Res. 8:1-9(2001) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2), VARIANT LYS-531.
[7]	"Complete sequencing and characterization of 21,243 full-length human cDNAs." Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S. , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S. Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 3 AND 4), VARIANT LYS-531. Tissue: Heart and Tongue.
[8]	"The DNA sequence of human chromosome 22." Dunham I., Hunt A.R., Collins J.E., Bruskiewich R., Beare D.M., Clamp M., Smink L.J., Ainscough R., Almeida J.P., Babbage A.K., Bagguley C., Bailey J., Barlow K.F., Bates K.N., Beasley O.P., Bird C.P., Blakey S.E., Bridgeman A.M. , Buck D., Burgess J., Burrill W.D., Burton J., Carder C., Carter N.P., Chen Y., Clark G., Clegg S.M., Cobley V.E., Cole C.G., Collier R.E., Connor R., Conroy D., Corby N.R., Coville G.J., Cox A.V., Davis J., Dawson E., Dhami P.D., Dockree C., Dodsworth S.J., Durbin R.M., Ellington A.G., Evans K.L., Fey J.M., Fleming K., French L., Garner A.A., Gilbert J.G.R., Goward M.E., Grafham D.V., Griffiths M.N.D., Hall C., Hall R.E., Hall-Tamlyn G., Heathcott R.W., Ho S., Holmes S., Hunt S.E., Jones M.C., Kershaw J., Kimberley A.M., King A., Laird G.K., Langford C.F., Leversha M.A., Lloyd C., Lloyd D.M., Martyn I.D., Mashreghi-Mohammadi M., Matthews L.H., Mccann O.T., Mcclay J., Mclaren S., McMurray A.A., Milne S.A., Mortimore B.J., Odell C.N., Pavitt R., Pearce A.V., Pearson D., Phillimore B.J.C.T., Phillips S.H., Plumb R.W., Ramsay H., Ramsey Y., Rogers L., Ross M.T., Scott C.E., Sehra H.K., Skuce C.D., Smalley S., Smith M.L., Soderlund C., Spragon L., Steward C.A., Sulston J.E., Swann R.M., Vaudin M., Wall M., Wallis J.M., Whiteley M.N., Willey D.L., Williams L., Williams S.A., Williamson H., Wilmer T.E., Wilming L., Wright C.L., Hubbard T., Bentley D.R., Beck S., Rogers J., Shimizu N., Minoshima S., Kawasaki K., Sasaki T., Asakawa S., Kudoh J., Shintani A., Shibuya K., Yoshizaki Y., Aoki N., Mitsuyama S., Roe B.A., Chen F., Chu L., Crabtree J., Deschamps S., Do A., Do T., Dorman A., Fang F., Fu Y., Hu P., Hua A., Kenton S., Lai H., Lao H.I., Lewis J., Lewis S., Lin S.-P., Loh P., Malaj E., Nguyen T., Pan H., Phan S., Qi S., Qian Y., Ray L., Ren Q., Shaull S., Sloan D., Song L., Wang Q., Wang Y., Wang Z., White J., Willingham D., Wu H., Yao Z., Zhan M., Zhang G., Chissoe S., Murray J., Miller N., Minx P., Fulton R., Johnson D., Bemis G., Bentley D., Bradshaw H., Bourne S., Cordes M., Du Z., Fulton L., Goela D., Graves T., Hawkins J., Hinds K., Kemp K., Latreille P., Layman D., Ozersky P., Rohlfing T., Scheet P., Walker C., Wamsley A., Wohldmann P., Pepin K., Nelson J., Korf I., Bedell J.A., Hillier L.W., Mardis E., Waterston R., Wilson R., Emanuel B.S., Shaikh T., Kurahashi H., Saitta S., Budarf M.L., McDermid H.E., Johnson A., Wong A.C.C., Morrow B.E., Edelmann L., Kim U.J., Shizuya H., Simon M.I., Dumanski J.P., Peyrard M., Kedra D., Seroussi E., Fransson I., Tapia I., Bruder C.E., O'Brien K.P., Wilkinson P., Bodenteich A., Hartman K., Hu X., Khan A.S., Lane L., Tilahun Y., Wright H. Nature 402:489-495(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D87812 mRNA. Translation: BAA13461.1. U66828 mRNA. Translation: AAB40651.1. U62733 mRNA. Translation: AAC51122.1. Y08682 mRNA. Translation: CAA69938.1. Y08683 mRNA. Translation: CAA69939.1. AB003286 Genomic DNA. Translation: BAA21492.1. AB051457 mRNA. Translation: BAB33340.1. Different initiation. AK297866 mRNA. Translation: BAH12680.1. AK299395 mRNA. Translation: BAH13024.1. U62317 Genomic DNA. Translation: AAB03343.1.
IPI	IPI00640400. IPI00877658. IPI00921936. IPI00922376.
PIR	G02860.
RefSeq	NP_001138606.1. NM_001145134.1. NP_001138607.1. NM_001145135.1. NP_001138608.1. NM_001145136.1. NP_001138609.1. NM_001145137.1. NP_004368.1. NM_004377.3. NP_689451.1. NM_152245.2. NP_689452.1. NM_152246.2.
UniGene	Hs.439777. Hs.609867.
3D structure databases
ProteinModelPortal	Q92523.
ModBase	Search...
Protein-protein interaction databases
STRING	9606.ENSP00000312189.
PTM databases
PhosphoSite	Q92523.
Polymorphism databases
DMDM	2493497.
Proteomic databases
PaxDb	Q92523.
PRIDE	Q92523.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENST00000312108; ENSP00000312189; ENSG00000205560. ENST00000360719; ENSP00000353945; ENSG00000205560. ENST00000395650; ENSP00000379011; ENSG00000205560. ENST00000405237; ENSP00000385486; ENSG00000205560. ENST00000440709; ENSP00000414713; ENSG00000205560. ENST00000457250; ENSP00000409342; ENSG00000205560.
GeneID	1375.
KEGG	hsa:1375.
UCSC	uc003bmk.4. human. uc011asa.2. human. uc011asb.2. human.
Organism-specific databases
CTD	1375.
GeneCards	GC22M051008.
HGNC	HGNC:2329. CPT1B.
HPA	HPA029583.
MIM	601987. gene.
neXtProt	NX_Q92523.
PharmGKB	PA26848.
HUGE	Search...
GenAtlas	Search...
Phylogenomic databases
eggNOG	NOG70127.
HOGENOM	HOG000233542.
HOVERGEN	HBG003458.
InParanoid	Q92523.
KO	K08765.
OMA	RDRGKFC.
OrthoDB	EOG4TXBR8.
PhylomeDB	Q92523.
Enzyme and pathway databases
BRENDA	2.3.1.21. 2681.
Pathway_Interaction_DB	hnf3bpathway. FOXA2 and FOXA3 transcription factor networks.
Reactome	REACT_111217. Metabolism. REACT_11163. Activated AMPK stimulates fatty-acid oxidation in muscle.
SABIO-RK	Q92523.
UniPathway	UPA00659.
Gene expression databases
ArrayExpress	Q92523.
Bgee	Q92523.
CleanEx	HS_CPT1B.
Genevestigator	Q92523.
GermOnline	ENSG00000100288. Homo sapiens.
Family and domain databases
InterPro	IPR000542. Carn_acyl_trans. [Graphical view]
PANTHER	PTHR22589. PTHR22589. 1 hit.
Pfam	PF00755. Carn_acyltransf. 1 hit. [Graphical view]
PROSITE	PS00439. ACYLTRANSF_C_1. 1 hit. PS00440. ACYLTRANSF_C_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	CPT1B. human.
GenomeRNAi	1375.
NextBio	5575.
SOURCE	Search...

Entry information

Entry name

CPT1B_HUMAN

Accession

Primary (citable) accession number: Q92523
Secondary accession number(s): B7Z4U4 , B7Z5T8, E9PCP2, Q13389, Q99655, Q9BY90

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1997
Last modified:	May 29, 2013
This is version 123 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program

Disclaimer

Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.