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Protein
Submitted name:

Parathyroid hormone-related protein

Gene

Pthlh

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-418555. G alpha (s) signalling events.

Names & Taxonomyi

Protein namesi
Submitted name:
Parathyroid hormone-related proteinImported
Gene namesi
Name:PthlhImported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:97800. Pthlh.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424Sequence analysisAdd
BLAST
Chaini25 – 175151Sequence analysisPRO_5006751134Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000051433.

Structurei

3D structure databases

SMRiQ924X4. Positions 37-70.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410IW2I. Eukaryota.
ENOG41126XH. LUCA.
GeneTreeiENSGT00390000004933.
HOVERGENiHBG003236.
OMAiATNTKNY.
OrthoDBiEOG7FBRK8.
TreeFamiTF332953.

Family and domain databases

InterProiIPR003626. PTH-rel.
IPR001415. PTH/PTH-rel.
[Graphical view]
PANTHERiPTHR17223. PTHR17223. 1 hit.
PfamiPF01279. Parathyroid. 1 hit.
[Graphical view]
SMARTiSM00087. PTH. 1 hit.
[Graphical view]
PROSITEiPS00335. PARATHYROID. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q924X4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRRLVQQWS VLVFLLSYSV PSRGRSVEGL GRRLKRAVSE HQLLHDKGKS
60 70 80 90 100
IQDLRRRFFL HHLIAEIHTA EIRATSEVSP NSKPAPNTKN HPVRFGSDDE
110 120 130 140 150
GRYLTQETNK VETYKEQPLK TPGKKKKGKP GKRREQEKKK RRTRSAWPST
160 170
AASGLLEDPL PHTSRPSLEP SLRTH
Length:175
Mass (Da):20,096
Last modified:December 1, 2001 - v1
Checksum:i6D22DBCC31900B45
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156278 Genomic DNA. No translation available.
AJ278119 mRNA. Translation: CAC39218.1.
RefSeqiNP_032996.2. NM_008970.4.
UniGeneiMm.28440.

Genome annotation databases

EnsembliENSMUST00000052296; ENSMUSP00000051433; ENSMUSG00000048776.
ENSMUST00000204197; ENSMUSP00000145509; ENSMUSG00000048776.
GeneIDi19227.
KEGGimmu:19227.
UCSCiuc009esx.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC156278 Genomic DNA. No translation available.
AJ278119 mRNA. Translation: CAC39218.1.
RefSeqiNP_032996.2. NM_008970.4.
UniGeneiMm.28440.

3D structure databases

SMRiQ924X4. Positions 37-70.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000051433.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000052296; ENSMUSP00000051433; ENSMUSG00000048776.
ENSMUST00000204197; ENSMUSP00000145509; ENSMUSG00000048776.
GeneIDi19227.
KEGGimmu:19227.
UCSCiuc009esx.2. mouse.

Organism-specific databases

CTDi5744.
MGIiMGI:97800. Pthlh.

Phylogenomic databases

eggNOGiENOG410IW2I. Eukaryota.
ENOG41126XH. LUCA.
GeneTreeiENSGT00390000004933.
HOVERGENiHBG003236.
OMAiATNTKNY.
OrthoDBiEOG7FBRK8.
TreeFamiTF332953.

Enzyme and pathway databases

ReactomeiR-MMU-373080. Class B/2 (Secretin family receptors).
R-MMU-418555. G alpha (s) signalling events.

Miscellaneous databases

NextBioi296020.
SOURCEiSearch...

Family and domain databases

InterProiIPR003626. PTH-rel.
IPR001415. PTH/PTH-rel.
[Graphical view]
PANTHERiPTHR17223. PTHR17223. 1 hit.
PfamiPF01279. Parathyroid. 1 hit.
[Graphical view]
SMARTiSM00087. PTH. 1 hit.
[Graphical view]
PROSITEiPS00335. PARATHYROID. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C3H/HeJImported.
    Tissue: LungImported.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  3. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.
  4. Ensembl
    Submitted (OCT-2015) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ924X4_MOUSE
AccessioniPrimary (citable) accession number: Q924X4
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 13, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.