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Protein
Submitted name:

Integrin alpha 6 subchain

Gene

Itga6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • laminin binding Source: RGD
  • protein complex binding Source: RGD

GO - Biological processi

  • cellular response to organic cyclic compound Source: RGD
  • integrin-mediated signaling pathway Source: UniProtKB-KW
  • positive regulation of cell-substrate adhesion Source: RGD
  • single organismal cell-cell adhesion Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

IntegrinImported

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin alpha 6 subchainImported
Gene namesi
Name:Itga6Imported
Synonyms:inta6Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621633. Itga6.

Subcellular locationi

GO - Cellular componenti

  • cell-cell adherens junction Source: RGD
  • filopodium Source: RGD
  • integrin alpha6-beta4 complex Source: RGD
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2323Sequence analysisAdd
BLAST
Chaini24 – 9976Sequence analysisPRO_5004318553Add
BLAST

Proteomic databases

PaxDbiQ924W3.

Expressioni

Gene expression databases

BgeeiENSRNOG00000001518.

Interactioni

GO - Molecular functioni

  • laminin binding Source: RGD
  • protein complex binding Source: RGD

Protein-protein interaction databases

IntActiQ924W3. 1 interaction.
STRINGi10116.ENSRNOP00000039474.

Structurei

3D structure databases

ProteinModelPortaliQ924W3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3637. Eukaryota.
ENOG410XPVZ. LUCA.
HOGENOMiHOG000015786.
KOiK06485.

Family and domain databases

InterProiIPR013519. Int_alpha_beta-p.
[Graphical view]
PROSITEiPS51470. FG_GAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q924W3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAVAGQLCLL YLSAGLLARL STAFNLDTRE DNVIRKSGDP GSLFGFSLAM
60 70 80 90
HWQLQPEDKR LLLVGAPRAE ALPLQKANRT GGLYSCDITS RGPCTRIVF
Length:99
Mass (Da):10,765
Last modified:December 1, 2001 - v1
Checksum:i3F0A90BB12E79CE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei99 – 991Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ312933 mRNA. Translation: CAC38095.1.
RefSeqiNP_446177.1. NM_053725.1.
UniGeneiRn.22382.

Genome annotation databases

GeneIDi114517.
KEGGirno:114517.
UCSCiRGD:621633. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ312933 mRNA. Translation: CAC38095.1.
RefSeqiNP_446177.1. NM_053725.1.
UniGeneiRn.22382.

3D structure databases

ProteinModelPortaliQ924W3.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ924W3. 1 interaction.
STRINGi10116.ENSRNOP00000039474.

Proteomic databases

PaxDbiQ924W3.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi114517.
KEGGirno:114517.
UCSCiRGD:621633. rat.

Organism-specific databases

CTDi3655.
RGDi621633. Itga6.

Phylogenomic databases

eggNOGiKOG3637. Eukaryota.
ENOG410XPVZ. LUCA.
HOGENOMiHOG000015786.
KOiK06485.

Gene expression databases

BgeeiENSRNOG00000001518.

Family and domain databases

InterProiIPR013519. Int_alpha_beta-p.
[Graphical view]
PROSITEiPS51470. FG_GAP. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ924W3_RAT
AccessioniPrimary (citable) accession number: Q924W3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.