Q924W3 (Q924W3_RAT) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Integrin alpha 6 subchain EMBL CAC38095.1

Gene names

Name:	Itga6 RGD 621633
Synonyms:	inta6 EMBL CAC38095.1

Organism

Rattus norvegicus (Rat) EMBL CAC38095.1

Taxonomic identifier

10116 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Rattus

Protein attributes

Sequence length	99 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Keywords
Molecular function	Integrin EMBL CAC38095.1
Gene Ontology (GO)
Biological_process	brown fat cell differentiation Inferred from electronic annotation. Source: Compara cell adhesion mediated by integrin Inferred from electronic annotation. Source: Compara cell-cell adhesion Inferred from mutant phenotype PubMed 16557522. Source: RGD cell-matrix adhesion Inferred from electronic annotation. Source: Compara cellular response to extracellular stimulus Inferred from electronic annotation. Source: Compara cellular response to organic cyclic compound Inferred from expression pattern Ref.2. Source: RGD filopodium assembly Inferred from electronic annotation. Source: Compara integrin-mediated signaling pathway Inferred from electronic annotation. Source: UniProtKB-KW leukocyte migration Inferred from electronic annotation. Source: Compara odontogenesis of dentin-containing tooth Inferred from electronic annotation. Source: Compara positive regulation of cell-cell adhesion Inferred from electronic annotation. Source: Compara positive regulation of cell-substrate adhesion Inferred from mutant phenotype Ref.2. Source: RGD
Cellular_component	alpha6-beta4 integrin complex Inferred from direct assay Ref.2. Source: RGD basal plasma membrane Inferred from electronic annotation. Source: Compara basement membrane Inferred from electronic annotation. Source: Compara cell-cell adherens junction Inferred from direct assay PubMed 16608848. Source: RGD external side of plasma membrane Inferred from electronic annotation. Source: Compara filopodium Inferred from direct assay Ref.2. Source: RGD hemidesmosome Inferred from electronic annotation. Source: Compara
Molecular_function	protein complex binding Inferred from direct assay Ref.2. Source: RGD
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	99	1	EMBL CAC38095.1

Sequences

	Sequence		Length	Mass (Da)
	Q924W3 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 3F0A90BB12E79CE1	FASTA	99	10,765
	10 20 30 40 50 60 MAVAGQLCLL YLSAGLLARL STAFNLDTRE DNVIRKSGDP GSLFGFSLAM HWQLQPEDKR 70 80 90 LLLVGAPRAE ALPLQKANRT GGLYSCDITS RGPCTRIVF

References

[1]	Herlevsen M.C. Thesis (2001), Department of Bio und Geowissenschaften, Univertsity of Karlsruhe, Karlsruhe, Germany Cited for: NUCLEOTIDE SEQUENCE.
[2]	"The association of the tetraspanin D6.1A with the alpha6beta4 integrin supports cell motility and liver metastasis formation." Herlevsen M., Schmidt D.S., Miyazaki K., Zoller M. J. Cell Sci. 116:4373-4390(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AJ312933 mRNA. Translation: CAC38095.1.
IPI	IPI00205166.
RefSeq	NP_446177.1. NM_053725.1.
UniGene	Rn.22382.
3D structure databases
ProteinModelPortal	Q924W3.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q924W3. 1 interaction.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	114517.
KEGG	rno:114517.
UCSC	RGD:621633. rat.
Organism-specific databases
CTD	3655.
RGD	621633. Itga6.
Phylogenomic databases
HOGENOM	HOG000015786.
InParanoid	Q924W3.
KO	K06485.
OrthoDB	EOG4G4GPM.
Gene expression databases
Genevestigator	Q924W3.
Family and domain databases
InterPro	IPR013519. Int_alpha_beta-p. [Graphical view]
SMART	SM00191. Int_alpha. 1 hit. [Graphical view]
PROSITE	PS51470. FG_GAP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	618643.

Entry information

Entry name

Q924W3_RAT

Accession

Primary (citable) accession number: Q924W3

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	April 3, 2013
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)