Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q924W3

- Q924W3_RAT

UniProt

Q924W3 - Q924W3_RAT

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Submitted name:

Integrin alpha 6 subchain

Gene

Itga6

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. laminin binding Source: RGD
  2. protein complex binding Source: RGD

GO - Biological processi

  1. brown fat cell differentiation Source: Ensembl
  2. cell adhesion mediated by integrin Source: Ensembl
  3. cell-matrix adhesion Source: Ensembl
  4. cellular response to extracellular stimulus Source: Ensembl
  5. cellular response to organic cyclic compound Source: RGD
  6. filopodium assembly Source: Ensembl
  7. integrin-mediated signaling pathway Source: UniProtKB-KW
  8. leukocyte migration Source: Ensembl
  9. negative regulation of extrinsic apoptotic signaling pathway Source: Ensembl
  10. odontogenesis of dentin-containing tooth Source: Ensembl
  11. positive regulation of apoptotic process Source: Ensembl
  12. positive regulation of cell-cell adhesion Source: Ensembl
  13. positive regulation of cell-substrate adhesion Source: RGD
  14. positive regulation of phosphorylation Source: Ensembl
  15. positive regulation of transcription from RNA polymerase II promoter Source: Ensembl
  16. single organismal cell-cell adhesion Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

IntegrinImported

Enzyme and pathway databases

ReactomeiREACT_197259. Laminin interactions.
REACT_199129. Assembly of collagen fibrils and other multimeric structures.

Names & Taxonomyi

Protein namesi
Submitted name:
Integrin alpha 6 subchainImported
Gene namesi
Name:Itga6Imported
Synonyms:inta6Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621633. Itga6.

Subcellular locationi

GO - Cellular componenti

  1. basal plasma membrane Source: Ensembl
  2. basement membrane Source: Ensembl
  3. cell-cell adherens junction Source: RGD
  4. external side of plasma membrane Source: Ensembl
  5. filopodium Source: RGD
  6. hemidesmosome Source: Ensembl
  7. integrin alpha6-beta4 complex Source: RGD
Complete GO annotation...

Expressioni

Gene expression databases

ExpressionAtlasiQ924W3. baseline and differential.
GenevestigatoriQ924W3.

Interactioni

Protein-protein interaction databases

IntActiQ924W3. 1 interaction.

Structurei

3D structure databases

ProteinModelPortaliQ924W3.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

RepeatSAAS annotation

Phylogenomic databases

HOGENOMiHOG000015786.
KOiK06485.

Family and domain databases

InterProiIPR013519. Int_alpha_beta-p.
[Graphical view]
SMARTiSM00191. Int_alpha. 1 hit.
[Graphical view]
PROSITEiPS51470. FG_GAP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q924W3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAVAGQLCLL YLSAGLLARL STAFNLDTRE DNVIRKSGDP GSLFGFSLAM
60 70 80 90
HWQLQPEDKR LLLVGAPRAE ALPLQKANRT GGLYSCDITS RGPCTRIVF
Length:99
Mass (Da):10,765
Last modified:December 1, 2001 - v1
Checksum:i3F0A90BB12E79CE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei99 – 991Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ312933 mRNA. Translation: CAC38095.1.
RefSeqiNP_446177.1. NM_053725.1.
UniGeneiRn.22382.

Genome annotation databases

GeneIDi114517.
KEGGirno:114517.
UCSCiRGD:621633. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ312933 mRNA. Translation: CAC38095.1 .
RefSeqi NP_446177.1. NM_053725.1.
UniGenei Rn.22382.

3D structure databases

ProteinModelPortali Q924W3.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q924W3. 1 interaction.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 114517.
KEGGi rno:114517.
UCSCi RGD:621633. rat.

Organism-specific databases

CTDi 3655.
RGDi 621633. Itga6.

Phylogenomic databases

HOGENOMi HOG000015786.
KOi K06485.

Enzyme and pathway databases

Reactomei REACT_197259. Laminin interactions.
REACT_199129. Assembly of collagen fibrils and other multimeric structures.

Miscellaneous databases

NextBioi 618643.

Gene expression databases

ExpressionAtlasi Q924W3. baseline and differential.
Genevestigatori Q924W3.

Family and domain databases

InterProi IPR013519. Int_alpha_beta-p.
[Graphical view ]
SMARTi SM00191. Int_alpha. 1 hit.
[Graphical view ]
PROSITEi PS51470. FG_GAP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Herlevsen M.C.
    Thesis (2001), Department of Bio und Geowissenschaften, Univertsity of Karlsruhe, Karlsruhe, Germany
    Cited for: NUCLEOTIDE SEQUENCE.
  2. "The association of the tetraspanin D6.1A with the alpha6beta4 integrin supports cell motility and liver metastasis formation."
    Herlevsen M., Schmidt D.S., Miyazaki K., Zoller M.
    J. Cell Sci. 116:4373-4390(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ924W3_RAT
AccessioniPrimary (citable) accession number: Q924W3
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)