Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

G-protein-coupled receptor 74

Gene

Npffr2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
G-protein-coupled receptor 74Imported
Gene namesi
Name:Npffr2Imported
Synonyms:Gpr74Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1860130. Npffr2.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei47 – 7428HelicalSequence analysisAdd
BLAST
Transmembranei86 – 10621HelicalSequence analysisAdd
BLAST
Transmembranei126 – 14419HelicalSequence analysisAdd
BLAST
Transmembranei164 – 18724HelicalSequence analysisAdd
BLAST
Transmembranei221 – 24323HelicalSequence analysisAdd
BLAST
Transmembranei276 – 29823HelicalSequence analysisAdd
BLAST
Transmembranei318 – 33720HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ924N0.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040033.

Structurei

3D structure databases

ProteinModelPortaliQ924N0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini65 – 334270G_PROTEIN_RECEP_F1_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG099624.

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR005395. NPFF_rcpt.
IPR005397. NPFF_rcpt_2.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01570. NPFFRECEPTOR.
PR01572. NPFFRECEPTR2.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q924N0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTMSEKWDS NSSESWNHIW SGNDTQHHWY SDINITYVNY YLHQPQVAAV
60 70 80 90 100
FISSYLLIFV LCMVGNTVVC FIVIRNRHMH TVTNFLILNL AISDLLVGIF
110 120 130 140 150
CMPITLLDNI IAGWPFGSSM CKISGLVQGI SVAASVFTLV AIAVDRFRCV
160 170 180 190 200
VYPFKPKLTV KTAFVTIVII WGLAIAIMTP SAIMLHVQEE KYYRVRLSSH
210 220 230 240 250
NKTSTVYWCR EDWPRHEMRR IYTTVLFAII YLAPLSLIVI MYARIGASLF
260 270 280 290 300
KTAAHCTGKQ RPVQCMYQEK QKVIKMLLTV ALLFILSWLP LWTLMMLSDY
310 320 330 340 350
TDLSPNKLRI INIYIYPFAH WLAFCNSSVN PIIYGFFNEN FRNGFQDAFQ
360 370 380 390 400
ICQKKAKPQE AYSLRAKRNI VINTSGLLVQ EPVSQNPGGE NLGCGKSADN

PHRNP
Length:405
Mass (Da):46,248
Last modified:December 1, 2001 - v1
Checksum:i8592068E1A17D64B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF236084 mRNA. Translation: AAK58514.1.
UniGeneiMm.447881.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF236084 mRNA. Translation: AAK58514.1.
UniGeneiMm.447881.

3D structure databases

ProteinModelPortaliQ924N0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000040033.

Protein family/group databases

GPCRDBiSearch...

Proteomic databases

PaxDbiQ924N0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1860130. Npffr2.

Phylogenomic databases

eggNOGiKOG3656. Eukaryota.
ENOG410XRW9. LUCA.
HOVERGENiHBG099624.

Miscellaneous databases

ChiTaRSiNpffr2. mouse.
SOURCEiSearch...

Family and domain databases

InterProiIPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
IPR005395. NPFF_rcpt.
IPR005397. NPFF_rcpt_2.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR00237. GPCRRHODOPSN.
PR01570. NPFFRECEPTOR.
PR01572. NPFFRECEPTR2.
SMARTiSM01381. 7TM_GPCR_Srsx. 1 hit.
[Graphical view]
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ924N0_MOUSE
AccessioniPrimary (citable) accession number: Q924N0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 11, 2016
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.