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Q924M0

- Q924M0_RAT

UniProt

Q924M0 - Q924M0_RAT

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Protein
Submitted name:

GABA type B receptor 1f

Gene

Gabbr1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. G-protein coupled GABA receptor activity Source: Ensembl

GO - Biological processi

  1. adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway Source: Ensembl
  2. gamma-aminobutyric acid signaling pathway Source: Ensembl
Complete GO annotation...

Keywords - Molecular functioni

ReceptorImported

Enzyme and pathway databases

ReactomeiREACT_233455. G alpha (i) signalling events.
REACT_236177. Class C/3 (Metabotropic glutamate/pheromone receptors).
REACT_242287. Activation of G protein gated Potassium channels.
REACT_242857. GABA B receptor activation.
REACT_249237. Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits.

Names & Taxonomyi

Protein namesi
Submitted name:
GABA type B receptor 1fImported
Submitted name:
Gamma-aminobutyric acid (GABA) B receptor 1, isoform CRA_aImported
Gene namesi
Name:Gabbr1Imported
ORF Names:rCG_58602Imported
OrganismiRattus norvegicus (Rat)
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621537. Gabbr1.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: Ensembl
  2. G-protein coupled receptor heterodimeric complex Source: Ensembl
  3. postsynaptic membrane Source: Ensembl
  4. presynaptic membrane Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevestigatoriQ924M0.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOGENOMiHOG000016575.
HOVERGENiHBG051688.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
IPR000436. Sushi_SCR_CCP.
[Graphical view]
PANTHERiPTHR10519. PTHR10519. 1 hit.
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF00084. Sushi. 2 hits.
[Graphical view]
PRINTSiPR01177. GABAB1RECPTR.
SMARTiSM00032. CCP. 2 hits.
[Graphical view]
SUPFAMiSSF53822. SSF53822. 1 hit.
SSF57535. SSF57535. 2 hits.
PROSITEiPS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
PS50923. SUSHI. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q924M0-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLLLLLVPLF LRPLGAGGAQ TPNATSEGCQ IIHPPWEGGI RYRGLTRDQV
60 70 80 90 100
KAINFLPVDY EIEYVCRGER EVVGPKVRKC LANGSWTDMD TPSRCVRICS
110 120 130 140 150
KSYLTLENGK VFLTGGDLPA LDGARVEFRC DPDFHLVGSS RSVCSQGQWS
160 170 180 190 200
TPKPHCQERR AVYIGALFPM SGGWPGGQAC QPAVEMALED VNSRRDILPD
210 220 230 240 250
YELKLIHHDS KCDPGQATKY LYELLYNDPI KIILMPGCSS VSTLVAEAAR
260 270 280 290 300
MWNLIVLSYG SSSPALSNRQ RFPTFFRTHP SATLHNPTRV KLFEKWGWKK
310 320 330 340 350
IATIQQTTEV FTSTLDDLEE RVKEAGIEIT FRQSFFSDPA VPVKNLKRQD
360 370 380 390 400
ARIIVGLFYE TEARKVFCEV YKERLFGKKY VWFLIGWYAD NWFKTYDPSI
410 420 430 440 450
NCTVEEMTEA VEGHITTEIV MLNPANTRSI SNMTSQEFVE KLTKRLKRHP
460 470 480 490 500
EETGGFQEAP LAYDAIWALA LALNKTSGGG GRSGVRLEDF NYNNQTITDQ
510 520 530 540 550
IYRAMNSSSF EGVSGHVVFD ASGSRMAWTL IEQLQGGSYK KIGYYDSTKD
560 570 580 590 600
DLSWSKTDKW IGGSPPADQT LVIKTFRFLS QKLFISVSVL SSLGIVLAVV
610 620 630 640 650
CLSFNIYNSH VRYIQNSQPN LNNLTAVGCS LALAAVFPLG LDGYHIGRSQ
660 670 680 690 700
FPFVCQARLW LLGLGFSLGY GSMFTKIWWV HTVFTKKEEK KEWRKTLEPW
710 720 730 740 750
KLYATVGLLV GMDVLTLAIW QIVDPLHRTI ETFAKEEPKE DIDVSILPQL
760 770 780 790 800
EHCSSKKMNT WLGELWSFAV SSDVQRRATV GGDSPICVWP APESIFYGYK
810 820 830 840 850
GLLLLLGIFL AYETKSVSTE KINDHRAVGM AIYNVAVLCL ITAPVTMILS
860 870 880 890 900
SQQDAAFAFA SLAIVFSSYI TLVVLFVPKM RRLITRGEWQ SETQDTMKTG
910 920 930 940 950
SSTNNNEEEK SRLLEKENRE LEKIIAEKEE RVSELRHQLQ SRQQLRSRRH
960 970 980
PPTPPDPSGG LPRGPSEPPD RLSCDGSRVH LLYK
Length:984
Mass (Da):110,742
Last modified:December 1, 2001 - v1
Checksum:iA93012CFA296FBDA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF283276 mRNA. Translation: AAK69540.1.
CH474093 Genomic DNA. Translation: EDL84628.1.
UniGeneiRn.30059.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF283276 mRNA. Translation: AAK69540.1 .
CH474093 Genomic DNA. Translation: EDL84628.1 .
UniGenei Rn.30059.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

RGDi 621537. Gabbr1.

Phylogenomic databases

HOGENOMi HOG000016575.
HOVERGENi HBG051688.

Enzyme and pathway databases

Reactomei REACT_233455. G alpha (i) signalling events.
REACT_236177. Class C/3 (Metabotropic glutamate/pheromone receptors).
REACT_242287. Activation of G protein gated Potassium channels.
REACT_242857. GABA B receptor activation.
REACT_249237. Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits.

Gene expression databases

Genevestigatori Q924M0.

Family and domain databases

InterProi IPR001828. ANF_lig-bd_rcpt.
IPR002455. GPCR3_GABA-B.
IPR017978. GPCR_3_C.
IPR002456. GPCR_3_GABA_rcpt_B1.
IPR028082. Peripla_BP_I.
IPR000436. Sushi_SCR_CCP.
[Graphical view ]
PANTHERi PTHR10519. PTHR10519. 1 hit.
Pfami PF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF00084. Sushi. 2 hits.
[Graphical view ]
PRINTSi PR01177. GABAB1RECPTR.
SMARTi SM00032. CCP. 2 hits.
[Graphical view ]
SUPFAMi SSF53822. SSF53822. 1 hit.
SSF57535. SSF57535. 2 hits.
PROSITEi PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
PS50923. SUSHI. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning and tissue distribution of a novel isoform of the rat GABA(B)R1 receptor subunit."
    Wei K., Eubanks J.H., Francis J., Jia Z., Snead O.C. 3rd
    NeuroReport 12:833-837(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Sprague-DawleyImported.
  2. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BNImported.

Entry informationi

Entry nameiQ924M0_RAT
AccessioniPrimary (citable) accession number: Q924M0
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 26, 2014
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)