Metastasis-associated protein MTA3
Reviewed-Annotation score: <p>Annotation score: 5 out of 5</p>
<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome.</p><p><a href='../manual/annotation_score' target='_top'>More...</a></p>Annotation score: 5 out of 5-Experimental evidence at protein leveli
<p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.</p><p><a href='../manual/protein_existence' target='_top'>More...</a></p> Select a section on the left to see content.
<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functioni
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6 (By similarity).
Regions
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Specifies the position(s) and type(s) of zinc fingers within the protein.</p><p><a href='../manual/zn_fing' target='_top'>More...</a></p>Zinc fingeri | 377 – 404 | 28 | GATA-type; atypical |   | | Add
BLAST |
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processi
- negative regulation of transcription, DNA-templated
- positive regulation of cell proliferation
<p>Inferred from Mutant Phenotype</p>
<p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
- positive regulation of G2/M transition of mitotic cell cycle
<p>Inferred from Mutant Phenotype</p>
<p>Describes annotations that are concluded from looking at variations or changes in a gene product such as mutations or abnormal levels and includes techniques such as knockouts, overexpression, anti-sense experiments and use of specific protein inhibitors.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#imp">GO evidence code guide</a></p> Inferred from mutant phenotypei
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Ligandi
DNA-binding, Metal-binding, ZincEnzyme and pathway databases
|
Reactome - a knowledgebase of biological pathways and processes<br/><a href='/database/88'>More..</a>Reactomei | R-MMU-73762. RNA Polymerase I Transcription Initiation.
|
<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi
| <p>Provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.</p><p><a href='../manual/protein_names' target='_top'>More...</a></p>Protein namesi | Recommended name: Metastasis-associated protein MTA3 |
| <p>Indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.</p><p><a href='../manual/gene_name' target='_top'>More...</a></p>Gene namesi | |
| <p>Provides information on the name(s) of the organism that is the source of the protein sequence.</p><p><a href='../manual/organism-name' target='_top'>More...</a></p>Organismi | Mus musculus (Mouse) |
| <p>Shows the unique identifier assigned by the <span class="caps">NCBI</span> to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.</p><p><a href='../manual/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri | 10090 [NCBI] |
| <p>Contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.</p><p><a href='../manual/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineagei | cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus |
| <p>Is present for entries that are part of a <a href="/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.</p><p><a href='../manual/proteomes_manual' target='_top'>More...</a></p>Proteomesi | - UP000000589
<p>A UniProt <a href="/manual/proteomes_manual">proteome</a> can consist of several components. <br />The component name refers to the genomic component encoding a set of proteins. <br />These range from a single component such as Viral genomes to several components as in the case of eukaryotic chromosomes. They may also represent different stages in a genome project and include components such as contigs, scaffolds or Whole Genome Shotgun (WGS) master records.</p><p><a href='../manual/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 17
|
Organism-specific databases
|
Mouse genome database (MGD) from Mouse Genome Informatics (MGI)<br/><a href='/database/60'>More..</a>MGIi | MGI:2151172. Mta3.
|
<p>Provides information on the location and the topology of the mature protein in the cell.</p><p><a href='../manual/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi
- Nucleus
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
<p>Manually curated information for which there is published experimental evidence.</p>
<p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment ini
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
- Cytoplasm
<p>Manually curated information for which there is published experimental evidence.</p>
<p><a href="/manual/evidences#ECO:0000269">More…</a></p> Manual assertion based on experiment ini
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), SUBCELLULAR LOCATION.
<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti
- cohesin complex
<p>Inferred from Direct Assay</p>
<p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- cytoplasm
<p>Inferred from Direct Assay</p>
<p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- intracellular membrane-bounded organelle
- nucleoplasm
- nucleus
<p>Inferred from Direct Assay</p>
<p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
- NuRD complex
<p>Inferred from Direct Assay</p>
<p>Used to indicate a direct assay for the function, process or component indicated by the GO term.</p>
<p>More information in the <a href="http://geneontology.org/page/guide-go-evidence-codes#ida">GO evidence code guide</a></p> Inferred from direct assayi
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti
Cytoplasm, Nucleus<p>Describes post-translational modifications (PTMs) and/or processing events.</p><p><a href='../manual/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi
Molecule processing
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the extent of a polypeptide chain in the mature protein following processing.</p><p><a href='../manual/chain' target='_top'>More...</a></p>Chaini | 1 – 591 | 591 | Metastasis-associated protein MTA3 | | PRO_0000083499 | Add
BLAST |
Amino acid modifications
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - PTMi
PhosphoproteinProteomic databases
|
Encyclopedia of Proteome Dynamics<br/><a href='/database/205'>More..</a>EPDi | Q924K8.
|
|
MaxQB - The MaxQuant DataBase<br/><a href='/database/186'>More..</a>MaxQBi | Q924K8.
|
|
PaxDb, a database of protein abundance averages across all three domains of life<br/><a href='/database/173'>More..</a>PaxDbi | Q924K8.
|
|
PeptideAtlas<br/><a href='/database/71'>More..</a>PeptideAtlasi | Q924K8.
|
|
PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | Q924K8.
|
PTM databases
|
iPTMnet integrated resource for PTMs in systems biology context<br/><a href='/database/200'>More..</a>iPTMneti | Q924K8.
|
|
Comprehensive resource for the study of human and mouse PTMs<br/><a href='/database/123'>More..</a>PhosphoSitei | Q924K8.
|
<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.</p><p><a href='../manual/expression_section' target='_top'>More...</a></p>Expressioni
<p>Provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified ‘at protein level’.<br />Examples: <a href="/uniprot/P92958#expression"><span class="caps">P92958</span></a>, <a href="/uniprot/Q8TDN4#expression"><span class="caps">Q8TDN4</span></a>, <a href="/uniprot/O14734#expression"><span class="caps">O14734</span></a></p><p><a href='../manual/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi
Expressed in heart, brain, spleen, lung, liver and kidney.
Gene expression databases
|
Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | ENSMUSG00000055817.
|
|
CleanEx database of gene expression profiles<br/><a href='/database/8'>More..</a>CleanExi | MM_MTA3.
|
|
ExpressionAtlas, Differential and Baseline Expression<br/><a href='/database/4'>More..</a>ExpressionAtlasi | Q924K8. baseline and differential.
|
|
Genevisible search portal to normalized and curated expression data from Genevestigator<br/><a href='/database/194'>More..</a>Genevisiblei | Q924K8. MM.
|
<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactioni
<p>Provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="/help/function_section">‘Function’</a> section).</p><p><a href='../manual/subunit_structure' target='_top'>More...</a></p>Subunit structurei
Component of the nucleosome-remodeling and histone-deacetylase multiprotein complex (NuRD). Interacts with BCL6 (By similarity). Interacts with NACC2 (By similarity).
Protein-protein interaction databases
|
The Biological General Repository for Interaction Datasets (BioGrid)<br/><a href='/database/184'>More..</a>BioGridi | 228046. 12 interactions.
|
|
Database of interacting proteins<br/><a href='/database/16'>More..</a>DIPi | DIP-61664N.
|
|
Protein interaction database and analysis system<br/><a href='/database/51'>More..</a>IntActi | Q924K8. 4 interactions.
|
|
Molecular INTeraction database<br/><a href='/database/158'>More..</a>MINTi | MINT-4102500.
|
|
STRING: functional protein association networks<br/><a href='/database/141'>More..</a>STRINGi | 10090.ENSMUSP00000068931.
|
<p>Provides information on the tertiary and secondary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structurei
Secondary structure
Legend: HelixTurnBeta strand
Show more detailsHide details3D structure databases
Miscellaneous databases
|
Relative evolutionary importance of amino acids within a protein sequence<br/><a href='/database/168'>More..</a>EvolutionaryTracei | Q924K8.
|
<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi
Domains and Repeats
<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi
Contains 1
BAH domain.
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
Contains 1
ELM2 domain.
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
Contains 1
SANT domain.
<p>Manual validated information which has been generated by the UniProtKB automatic annotation system.</p>
<p><a href="/manual/evidences#ECO:0000255">More…</a></p> Manual assertion according to rulesi
Zinc finger
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Specifies the position(s) and type(s) of zinc fingers within the protein.</p><p><a href='../manual/zn_fing' target='_top'>More...</a></p>Zinc fingeri | 377 – 404 | 28 | GATA-type; atypical | | | Add
BLAST |
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini
Zinc-fingerPhylogenomic databases
|
evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | KOG3554. Eukaryota.
ENOG410XSAJ. LUCA.
|
|
Ensembl GeneTree<br/><a href='/database/162'>More..</a>GeneTreei | ENSGT00580000081398.
|
|
The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000045387.
|
|
The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG002598.
|
|
InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | Q924K8.
|
|
KEGG Orthology (KO)<br/><a href='/database/164'>More..</a>KOi | K11660.
|
|
Identification of Orthologs from Complete Genome Data<br/><a href='/database/137'>More..</a>OMAi | KHNYDLS.
|
|
Database of Orthologous Groups<br/><a href='/database/143'>More..</a>OrthoDBi | EOG091G04Z4.
|
|
Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | Q924K8.
|
|
TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF106444.
|
Family and domain databases
|
Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR001025. BAH_dom.
IPR000949. ELM2_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR000679. Znf_GATA.
[Graphical view] |
|
Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF01426. BAH. 1 hit.
PF01448. ELM2. 1 hit.
PF00320. GATA. 1 hit.
[Graphical view] |
|
Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00439. BAH. 1 hit.
SM01189. ELM2. 1 hit.
SM00717. SANT. 1 hit.
SM00401. ZnF_GATA. 1 hit.
[Graphical view] |
|
Superfamily database of structural and functional annotation<br/><a href='/database/155'>More..</a>SUPFAMi | SSF46689. SSF46689. 1 hit.
|
|
PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS51038. BAH. 1 hit.
PS51156. ELM2. 1 hit.
PS51293. SANT. 1 hit.
[Graphical view] |
<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequences (2)i
<p>Indicates if the <a href="/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.
This entry describes 2<p>Lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform.</p><p><a href='../manual/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basketAdded to basket
Experimental Info
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.</p><p><a href='../manual/conflict' target='_top'>More...</a></p>Sequence conflicti | 166 – 166 | 1 | E → EG in AAH22124 (PubMed:15489334). | | | |
Alternative sequence
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | Actions |
|---|
| <p>Describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.</p><p><a href='../manual/var_seq' target='_top'>More...</a></p>Alternative sequencei | 506 – 512 | 7 | YADRHAE → CKTLFNS in isoform 2.
<p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p>
<p><a href="/manual/evidences#ECO:0000303">More…</a></p> Manual assertion based on opinion ini Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
| | VSP_001605 | |
| <p>Describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting. The information stored in this subsection is used to automatically construct alternative protein sequence(s) for display.</p><p><a href='../manual/var_seq' target='_top'>More...</a></p>Alternative sequencei | 513 – 591 | 79 | Missing in isoform 2.
<p>Manually curated information that is based on statements in scientific articles for which there is no experimental support.</p>
<p><a href="/manual/evidences#ECO:0000303">More…</a></p> Manual assertion based on opinion ini Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
| | VSP_001606 | Add
BLAST |
Sequence databases
Genome annotation databases
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Coding sequence diversityi
Alternative splicing<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesi
Sequence databases
3D structure databases
Protein-protein interaction databases
|
The Biological General Repository for Interaction Datasets (BioGrid)<br/><a href='/database/184'>More..</a>BioGridi | 228046. 12 interactions.
|
|
Database of interacting proteins<br/><a href='/database/16'>More..</a>DIPi | DIP-61664N.
|
|
Protein interaction database and analysis system<br/><a href='/database/51'>More..</a>IntActi | Q924K8. 4 interactions.
|
|
Molecular INTeraction database<br/><a href='/database/158'>More..</a>MINTi | MINT-4102500.
|
|
STRING: functional protein association networks<br/><a href='/database/141'>More..</a>STRINGi | 10090.ENSMUSP00000068931.
|
PTM databases
|
iPTMnet integrated resource for PTMs in systems biology context<br/><a href='/database/200'>More..</a>iPTMneti | Q924K8.
|
|
Comprehensive resource for the study of human and mouse PTMs<br/><a href='/database/123'>More..</a>PhosphoSitei | Q924K8.
|
Proteomic databases
|
Encyclopedia of Proteome Dynamics<br/><a href='/database/205'>More..</a>EPDi | Q924K8.
|
|
MaxQB - The MaxQuant DataBase<br/><a href='/database/186'>More..</a>MaxQBi | Q924K8.
|
|
PaxDb, a database of protein abundance averages across all three domains of life<br/><a href='/database/173'>More..</a>PaxDbi | Q924K8.
|
|
PeptideAtlas<br/><a href='/database/71'>More..</a>PeptideAtlasi | Q924K8.
|
|
PRoteomics IDEntifications database<br/><a href='/database/130'>More..</a>PRIDEi | Q924K8.
|
Protocols and materials databases
|
The DNASU plasmid repository<br/><a href='/database/167'>More..</a>DNASUi | 116871.
|
|
Structural Biology Knowledgebase | Search...
|
Genome annotation databases
Organism-specific databases
|
Comparative Toxicogenomics Database<br/><a href='/database/140'>More..</a>CTDi | 57504.
|
|
Mouse genome database (MGD) from Mouse Genome Informatics (MGI)<br/><a href='/database/60'>More..</a>MGIi | MGI:2151172. Mta3.
|
Phylogenomic databases
|
evolutionary genealogy of genes: Non-supervised Orthologous Groups<br/><a href='/database/152'>More..</a>eggNOGi | KOG3554. Eukaryota.
ENOG410XSAJ. LUCA.
|
|
Ensembl GeneTree<br/><a href='/database/162'>More..</a>GeneTreei | ENSGT00580000081398.
|
|
The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms<br/><a href='/database/44'>More..</a>HOGENOMi | HOG000045387.
|
|
The HOVERGEN Database of Homologous Vertebrate Genes<br/><a href='/database/45'>More..</a>HOVERGENi | HBG002598.
|
|
InParanoid: Eukaryotic Ortholog Groups<br/><a href='/database/146'>More..</a>InParanoidi | Q924K8.
|
|
KEGG Orthology (KO)<br/><a href='/database/164'>More..</a>KOi | K11660.
|
|
Identification of Orthologs from Complete Genome Data<br/><a href='/database/137'>More..</a>OMAi | KHNYDLS.
|
|
Database of Orthologous Groups<br/><a href='/database/143'>More..</a>OrthoDBi | EOG091G04Z4.
|
|
Database for complete collections of gene phylogenies<br/><a href='/database/144'>More..</a>PhylomeDBi | Q924K8.
|
|
TreeFam database of animal gene trees<br/><a href='/database/185'>More..</a>TreeFami | TF106444.
|
Enzyme and pathway databases
|
Reactome - a knowledgebase of biological pathways and processes<br/><a href='/database/88'>More..</a>Reactomei | R-MMU-73762. RNA Polymerase I Transcription Initiation.
|
Miscellaneous databases
|
Relative evolutionary importance of amino acids within a protein sequence<br/><a href='/database/168'>More..</a>EvolutionaryTracei | Q924K8.
|
|
Protein Ontology<br/><a href='/database/181'>More..</a>PROi | Q924K8.
|
|
The Stanford Online Universal Resource for Clones and ESTs<br/><a href='/database/99'>More..</a>SOURCEi | Search...
|
Gene expression databases
|
Bgee dataBase for Gene Expression Evolution<br/><a href='/database/133'>More..</a>Bgeei | ENSMUSG00000055817.
|
|
CleanEx database of gene expression profiles<br/><a href='/database/8'>More..</a>CleanExi | MM_MTA3.
|
|
ExpressionAtlas, Differential and Baseline Expression<br/><a href='/database/4'>More..</a>ExpressionAtlasi | Q924K8. baseline and differential.
|
|
Genevisible search portal to normalized and curated expression data from Genevestigator<br/><a href='/database/194'>More..</a>Genevisiblei | Q924K8. MM.
|
Family and domain databases
|
Integrated resource of protein families, domains and functional sites<br/><a href='/database/52'>More..</a>InterProi | IPR001025. BAH_dom.
IPR000949. ELM2_dom.
IPR009057. Homeodomain-like.
IPR001005. SANT/Myb.
IPR017884. SANT_dom.
IPR000679. Znf_GATA.
[Graphical view] |
|
Pfam protein domain database<br/><a href='/database/73'>More..</a>Pfami | PF01426. BAH. 1 hit.
PF01448. ELM2. 1 hit.
PF00320. GATA. 1 hit.
[Graphical view] |
|
Simple Modular Architecture Research Tool; a protein domain database<br/><a href='/database/97'>More..</a>SMARTi | SM00439. BAH. 1 hit.
SM01189. ELM2. 1 hit.
SM00717. SANT. 1 hit.
SM00401. ZnF_GATA. 1 hit.
[Graphical view] |
|
Superfamily database of structural and functional annotation<br/><a href='/database/155'>More..</a>SUPFAMi | SSF46689. SSF46689. 1 hit.
|
|
PROSITE; a protein domain and family database<br/><a href='/database/84'>More..</a>PROSITEi | PS51038. BAH. 1 hit.
PS51156. ELM2. 1 hit.
PS51293. SANT. 1 hit.
[Graphical view] |
|
ProtoNet; Automatic hierarchical classification of proteins<br/><a href='/database/85'>More..</a>ProtoNeti | Search...
|
<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationi
| <p>Provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.</p><p><a href='../manual/entry_name' target='_top'>More...</a></p>Entry namei | MTA3_MOUSE |
| <p>Provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.</p><p><a href='../manual/accession_numbers' target='_top'>More...</a></p>Accessioni | Q924K8Primary (citable) accession number: Q924K8
Secondary accession number(s): Q8VC18 |
| <p>Shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="help/canonical_and_isoforms">canonical sequence</a> are also displayed.</p><p><a href='../manual/entry_history' target='_top'>More...</a></p>Entry historyi | | Integrated into UniProtKB/Swiss-Prot: | February 28, 2003 | | Last sequence update: | December 1, 2001 | | Last modified: | September 7, 2016 | | This is version 135 of the entry and version 1 of the sequence. [Complete history] |
|
| <p>Indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).</p><p><a href='../manual/entry_status' target='_top'>More...</a></p>Entry statusi | Reviewed (UniProtKB/Swiss-Prot) |
| Annotation program | Chordata Protein Annotation Program |
<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi
<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi
3D-structure, Complete proteome, Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
- PDB cross-references
Index of Protein Data Bank (PDB) cross-references
- SIMILARITY comments
Index of protein domains and families
<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:| 100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry. |
| 90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
| 50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |
