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Protein
Submitted name:

Calcitonin receptor isoform Cla-1

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Calcitonin receptor isoform Cla-1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei164 – 190HelicalSequence analysisAdd BLAST27
Transmembranei202 – 220HelicalSequence analysisAdd BLAST19
Transmembranei251 – 271HelicalSequence analysisAdd BLAST21
Transmembranei278 – 301HelicalSequence analysisAdd BLAST24
Transmembranei313 – 337HelicalSequence analysisAdd BLAST25
Transmembranei358 – 379HelicalSequence analysisAdd BLAST22
Transmembranei391 – 411HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 41Sequence analysisAdd BLAST41
ChainiPRO_500431890542 – 495Sequence analysisAdd BLAST454

Structurei

3D structure databases

ProteinModelPortaliQ924D6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini71 – 155G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST85
Domaini165 – 412G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST248

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG102129.

Family and domain databases

CDDicd15274. 7tmB1_calcitonin_R. 1 hit.
Gene3Di4.10.1240.10. 1 hit.
InterProiView protein in InterPro
IPR003287. GCPR_2_calcitonin_rcpt_fam.
IPR017981. GPCR_2-like.
IPR001688. GPCR_2_calcitonin_rcpt.
IPR036445. GPCR_2_extracell_dom_sf.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
PANTHERiPTHR12011:SF84. PTHR12011:SF84. 1 hit.
PfamiView protein in Pfam
PF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
PRINTSiPR00361. CALCITONINR.
PR01350. CTRFAMILY.
PR00249. GPCRSECRETIN.
SMARTiView protein in SMART
SM00008. HormR. 1 hit.
SUPFAMiSSF111418. SSF111418. 1 hit.
PROSITEiView protein in PROSITE
PS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.

Sequencei

Sequence statusi: Complete.

Q924D6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTPRRSRVKR RNLRKPKMRF LLVNRFTLLL LLLVSPTPVL QAPTNLTDSG
60 70 80 90 100
LDQEPFLYLV GRKKLLDAQY KCYDRIHQLP SYEGEGLYCN RTWDGWMCWD
110 120 130 140 150
DTPAGATAYQ HCPDYFPDFD TAEKVSKYCD ENGEWFRHPD SNRTWSNYTL
160 170 180 190 200
CNAFTSEKLQ NAYVLYYLAL VGHSLSIAAL VASMLIFWIF KNLSCQRVTL
210 220 230 240 250
HKHMFLTYIL NSIIIIIHLV EVVPNGDLVR RDPISCKVLH FLHQYMMSCN
260 270 280 290 300
YFWMLCEGIY LHTLIVMAVF TDEQRLRWYY LLGWGFPIVP TIIHAITRAL
310 320 330 340 350
YYNDNCWLSA ETHLLYIIHG PVMVALVVNF FFLLNIVRVL VTKMRQTHEA
360 370 380 390 400
ESYMYLKAVK ATMVLVPLLG IQFVVFPWRP SNKVLGKIYD YLMHSLIHFQ
410 420 430 440 450
GFFVATIYCF CNHEVQVTLK RQWTQFKIQW SQRWGRRRPT NRVVSAPRAV
460 470 480 490
AFAEPDGLPI YICHQEPRNP PISNNEGEES TEMIPMNVIQ QDASA
Length:495
Mass (Da):57,970
Last modified:December 1, 2001 - v1
Checksum:iD8EF1846421E1870
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH010783
, AF333474, AF333475, AF333476, AF333477, AF333478, AF333479, AF333481, AF333482, AF333483, AF333484 Genomic DNA. Translation: AAK56132.1.
UniGeneiMm.4642.

Similar proteinsi

Entry informationi

Entry nameiQ924D6_MOUSE
AccessioniPrimary (citable) accession number: Q924D6
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)