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Protein
Submitted name:

Calcitonin receptor isoform Cla-2

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. calcitonin receptor activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Calcitonin receptor isoform Cla-2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Subcellular locationi

  1. Cell membrane SAAS annotation; Multi-pass membrane protein SAAS annotation

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

BgeeiQ924D5.
ExpressionAtlasiQ924D5. baseline and differential.
GenevestigatoriQ924D5.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG102129.

Family and domain databases

InterProiIPR003287. GCPR_2_calcitonin_rcpt_fam.
IPR017981. GPCR_2-like.
IPR001688. GPCR_2_calcitonin_rcpt.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
[Graphical view]
PRINTSiPR00361. CALCITONINR.
PR01350. CTRFAMILY.
PR00249. GPCRSECRETIN.
SMARTiSM00008. HormR. 1 hit.
[Graphical view]
PROSITEiPS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q924D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFLLVNRFT LLLLLLVSPT PVLQAPTNLT DSGLDQEPFL YLVGRKKLLD
60 70 80 90 100
AQYKCYDRIH QLPSYEGEGL YCNRTWDGWM CWDDTPAGAT AYQHCPDYFP
110 120 130 140 150
DFDTAEKVSK YCDENGEWFR HPDSNRTWSN YTLCNAFTSE KLQNAYVLYY
160 170 180 190 200
LALVGHSLSI AALVASMLIF WIFKNLSCQR VTLHKHMFLT YILNSIIIII
210 220 230 240 250
HLVEVVPNGD LVRRDPISCK VLHFLHQYMM SCNYFWMLCE GIYLHTLIVM
260 270 280 290 300
AVFTDEQRLR WYYLLGWGFP IVPTIIHAIT RALYYNDNCW LSAETHLLYI
310 320 330 340 350
IHGPVMVALV VNFFFLLNIV RVLVTKMRQT HEAESYMYLK AVKATMVLVP
360 370 380 390 400
LLGIQFVVFP WRPSNKVLGK IYDYLMHSLI HFQGFFVATI YCFCNHEVQV
410 420 430 440 450
TLKRQWTQFK IQWSQRWGRR RPTNRVVSAP RAVAFAEPDG LPIYICHQEP
460 470
RNPPISNNEG EESTEMIPMN VIQQDASA
Length:478
Mass (Da):55,808
Last modified:December 1, 2001 - v1
Checksum:i1DF08EA37A4D852D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF333485
, AF333474, AF333475, AF333476, AF333477, AF333478, AF333479, AF333481, AF333482, AF333483, AF333484 Genomic DNA. Translation: AAK56134.1.
UniGeneiMm.4642.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF333485
, AF333474, AF333475, AF333476, AF333477, AF333478, AF333479, AF333481, AF333482, AF333483, AF333484 Genomic DNA. Translation: AAK56134.1.
UniGeneiMm.4642.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

HOVERGENiHBG102129.

Gene expression databases

BgeeiQ924D5.
ExpressionAtlasiQ924D5. baseline and differential.
GenevestigatoriQ924D5.

Family and domain databases

InterProiIPR003287. GCPR_2_calcitonin_rcpt_fam.
IPR017981. GPCR_2-like.
IPR001688. GPCR_2_calcitonin_rcpt.
IPR001879. GPCR_2_extracellular_dom.
IPR000832. GPCR_2_secretin-like.
IPR017983. GPCR_2_secretin-like_CS.
[Graphical view]
PfamiPF00002. 7tm_2. 1 hit.
PF02793. HRM. 1 hit.
[Graphical view]
PRINTSiPR00361. CALCITONINR.
PR01350. CTRFAMILY.
PR00249. GPCRSECRETIN.
SMARTiSM00008. HormR. 1 hit.
[Graphical view]
PROSITEiPS00649. G_PROTEIN_RECEP_F2_1. 1 hit.
PS00650. G_PROTEIN_RECEP_F2_2. 1 hit.
PS50227. G_PROTEIN_RECEP_F2_3. 1 hit.
PS50261. G_PROTEIN_RECEP_F2_4. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Tissue-specific and ubiquitous promoters direct the expression of alternatively spliced transcripts from the calcitonin receptor gene."
    Anusaksathien O., Laplace C., Li X., Ren Y., Peng L., Goldring S.R., Galson D.L.
    J. Biol. Chem. 276:22663-22674(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 129Imported.

Entry informationi

Entry nameiQ924D5_MOUSE
AccessioniPrimary (citable) accession number: Q924D5
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 1, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.