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Protein
Submitted name:

Calcitonin receptor isoform Cla-2

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionG-protein coupled receptorSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Calcitonin receptor isoform Cla-2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei147 – 173HelicalSequence analysisAdd BLAST27
Transmembranei185 – 203HelicalSequence analysisAdd BLAST19
Transmembranei234 – 254HelicalSequence analysisAdd BLAST21
Transmembranei261 – 284HelicalSequence analysisAdd BLAST24
Transmembranei296 – 320HelicalSequence analysisAdd BLAST25
Transmembranei341 – 362HelicalSequence analysisAdd BLAST22
Transmembranei374 – 394HelicalSequence analysisAdd BLAST21

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500432094825 – 478Sequence analysisAdd BLAST454

Structurei

3D structure databases

ProteinModelPortaliQ924D5
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini54 – 138G_PROTEIN_RECEP_F2_3InterPro annotationAdd BLAST85
Domaini148 – 395G_PROTEIN_RECEP_F2_4InterPro annotationAdd BLAST248

Sequence similaritiesi

Belongs to the G-protein coupled receptor 2 family.SAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

HOVERGENiHBG102129

Family and domain databases

CDDicd15274 7tmB1_calcitonin_R, 1 hit
Gene3Di4.10.1240.10, 1 hit
InterProiView protein in InterPro
IPR003287 GCPR_2_calcitonin_rcpt_fam
IPR017981 GPCR_2-like
IPR001688 GPCR_2_calcitonin_rcpt
IPR036445 GPCR_2_extracell_dom_sf
IPR001879 GPCR_2_extracellular_dom
IPR000832 GPCR_2_secretin-like
IPR017983 GPCR_2_secretin-like_CS
PANTHERiPTHR12011:SF84 PTHR12011:SF84, 1 hit
PfamiView protein in Pfam
PF00002 7tm_2, 1 hit
PF02793 HRM, 1 hit
PRINTSiPR00361 CALCITONINR
PR01350 CTRFAMILY
PR00249 GPCRSECRETIN
SMARTiView protein in SMART
SM00008 HormR, 1 hit
SUPFAMiSSF111418 SSF111418, 1 hit
PROSITEiView protein in PROSITE
PS00649 G_PROTEIN_RECEP_F2_1, 1 hit
PS00650 G_PROTEIN_RECEP_F2_2, 1 hit
PS50227 G_PROTEIN_RECEP_F2_3, 1 hit
PS50261 G_PROTEIN_RECEP_F2_4, 1 hit

Sequencei

Sequence statusi: Complete.

Q924D5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRFLLVNRFT LLLLLLVSPT PVLQAPTNLT DSGLDQEPFL YLVGRKKLLD
60 70 80 90 100
AQYKCYDRIH QLPSYEGEGL YCNRTWDGWM CWDDTPAGAT AYQHCPDYFP
110 120 130 140 150
DFDTAEKVSK YCDENGEWFR HPDSNRTWSN YTLCNAFTSE KLQNAYVLYY
160 170 180 190 200
LALVGHSLSI AALVASMLIF WIFKNLSCQR VTLHKHMFLT YILNSIIIII
210 220 230 240 250
HLVEVVPNGD LVRRDPISCK VLHFLHQYMM SCNYFWMLCE GIYLHTLIVM
260 270 280 290 300
AVFTDEQRLR WYYLLGWGFP IVPTIIHAIT RALYYNDNCW LSAETHLLYI
310 320 330 340 350
IHGPVMVALV VNFFFLLNIV RVLVTKMRQT HEAESYMYLK AVKATMVLVP
360 370 380 390 400
LLGIQFVVFP WRPSNKVLGK IYDYLMHSLI HFQGFFVATI YCFCNHEVQV
410 420 430 440 450
TLKRQWTQFK IQWSQRWGRR RPTNRVVSAP RAVAFAEPDG LPIYICHQEP
460 470
RNPPISNNEG EESTEMIPMN VIQQDASA
Length:478
Mass (Da):55,808
Last modified:December 1, 2001 - v1
Checksum:i1DF08EA37A4D852D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AH010783
, AF333474, AF333475, AF333476, AF333477, AF333478, AF333479, AF333481, AF333482, AF333483, AF333484 Genomic DNA Translation: AAK56134.1
UniGeneiMm.4642

Similar proteinsi

Entry informationi

Entry nameiQ924D5_MOUSE
AccessioniPrimary (citable) accession number: Q924D5
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 25, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health