Glucose oxidase precursor - Talaromyces flavus

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Reviewed, UniProtKB/Swiss-Prot Q92452 (GOX_TALFL)

Last modified November 25, 2008. Version 45. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein names

Recommended name:
    Glucose oxidase
    EC=1.1.3.4
Alternative name(s):
    Glucose oxyhydrase
      Short name=GOD
    Beta-D-glucose:oxygen 1-oxido-reductase

Gene names

Name:

GOX

Organism

Talaromyces flavus

Taxonomic identifier

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › Talaromyces

Protein attributes

Sequence length	605 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Beta-D-glucose + O(2) = D-glucono-1,5-lactone + H(2)O(2).
Cofactor	FAD.
Sequence similarities	Belongs to the GMC oxidoreductase family.

Ontologies

Keywords
Domain	Signal
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
PTM	Glycoprotein
Gene Ontology (GO)
Biological process	cellular alcohol metabolic process Inferred from electronic annotation. Source: InterPro oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	FAD binding Inferred from electronic annotation. Source: InterPro glucose oxidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Signal peptide

22

Potential

Chain

583

Glucose oxidase

PRO_0000012339

Regions

Nucleotide binding

30

FAD Probable

Sites

Active site

1

By similarity

Amino acid modifications

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Glycosylation

1

N-linked (GlcNAc...) Potential

Sequences

Sequence

Length

Mass (Da)

Tools

Q92452-1 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 746F5F77FD1558D3
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605

65,769

        10         20         30         40         50         60 
MVSVFLSTLL LAAATVQAYL PAQQIDVQSS LLSDPSKVAG KTYDYIIAGG GLTGLTVAAK 

        70         80         90        100        110        120 
LTENPKIKVL VIEKGFYESN DGAIIEDPNA YGQIFGTTVD QNYLTVPLIN NRTNNIKAGK 

       130        140        150        160        170        180 
GLGGSTLING DSWTRPDKVQ IDSWEKVFGM EGWNWDSMFE YMKKAEAARA PTAAQLAAGH 

       190        200        210        220        230        240 
YFNATCHGTN GTVQSGARDN GQPWSPIMKA LMNTVSALGV PVQQDFLCGH PRGVSMIMNN 

       250        260        270        280        290        300 
VDENQVRVDA ARAWLLPSYQ RPNLEILTGQ MVGKVLFKQT ASGPQAVGVN FGTNKAVNFD 

       310        320        330        340        350        360 
VFAKHEVLLA AGSAISPLIL EYSGIGLKSV LDQANVTQLL DLPVGINMQD QTTTTVSSRA 

       370        380        390        400        410        420 
SAAGAGQGQA VFFANFTETF GDYAPQAREL LNTKLDQWAE ETVARGGFHN VTALKVQYEN 

       430        440        450        460        470        480 
YRNWLLDEDV AFAELFMDTE GKINFDLWDL IPFTRGSVHI LSSDPYLWQF ANDPKFFLNE 

       490        500        510        520        530        540 
FDLLGQAAAS KLARDLTSQG AMKEYFAGET LPGYNLVENA TLSQWSDYVL QNFRPNWHAV 

       550        560        570        580        590        600 
SSCSMMSREL GGVVDATAKV YGTQGLRVID GSIPPTQVSS HVMTIFYGMA LKVADAILDD 


YAKSA

References

[1]

"Isolation of the glucose oxidase gene from Talaromyces flavus and characterisation of its role in the biocontrol of Verticillium dahliae."
Murray F.R., Llewellyn D.J., Peacock W.J., Dennis E.S.
Curr. Genet. 32:367-375(1997) [PubMed: 9371889] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 32908.

Cross-references

Sequence databases
	U56240 Genomic DNA. Translation: AAB09442.1.
3D structure databases
HSSP	HSSP built from PDB template 1GPE based on UniProtKB P81156.
SMR	Q92452. Positions 19-605.
ModBase	Search...
Family and domain databases
InterPro	IPR012132. GMC_OxRdtase. IPR000172. GMC_OxRdtase_N. IPR007867. GMC_OxRtase_C. [Graphical view]
Pfam	PF05199. GMC_oxred_C. 1 hit. PF00732. GMC_oxred_N. 1 hit. [Graphical view]
PIRSF	PIRSF000137. Alcohol_oxidase. 1 hit.
PROSITE	PS00623. GMC_OXRED_1. 1 hit. PS00624. GMC_OXRED_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GOX_TALFL

Accession

Primary (citable) accession number: Q92452

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	November 25, 2008
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents