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Protein

Glucose oxidase

Gene

GOX

Organism
Talaromyces flavus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Beta-D-glucose + O2 = D-glucono-1,5-lactone + H2O2.

Cofactori

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei538Proton acceptorBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi44 – 73FADCuratedAdd BLAST30

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Protein family/group databases

mycoCLAPiGOX3A_TALFL.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose oxidase (EC:1.1.3.4)
Alternative name(s):
Beta-D-glucose:oxygen 1-oxido-reductase
Glucose oxyhydrase
Short name:
GOD
Gene namesi
Name:GOX
OrganismiTalaromyces flavus
Taxonomic identifieri5095 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesTrichocomaceaeTalaromyces

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000001233923 – 605Glucose oxidaseAdd BLAST583

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi111N-linked (GlcNAc...)Sequence analysis1
Glycosylationi183N-linked (GlcNAc...)Sequence analysis1
Glycosylationi190N-linked (GlcNAc...)Sequence analysis1
Glycosylationi335N-linked (GlcNAc...)Sequence analysis1
Glycosylationi375N-linked (GlcNAc...)Sequence analysis1
Glycosylationi410N-linked (GlcNAc...)Sequence analysis1
Glycosylationi519N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ92452.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GMC oxidoreductase family.Curated

Keywords - Domaini

Signal

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
4.10.450.10. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR027424. Glucose_Oxidase_domain_2.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamiPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
PROSITEiPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q92452-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSVFLSTLL LAAATVQAYL PAQQIDVQSS LLSDPSKVAG KTYDYIIAGG
60 70 80 90 100
GLTGLTVAAK LTENPKIKVL VIEKGFYESN DGAIIEDPNA YGQIFGTTVD
110 120 130 140 150
QNYLTVPLIN NRTNNIKAGK GLGGSTLING DSWTRPDKVQ IDSWEKVFGM
160 170 180 190 200
EGWNWDSMFE YMKKAEAARA PTAAQLAAGH YFNATCHGTN GTVQSGARDN
210 220 230 240 250
GQPWSPIMKA LMNTVSALGV PVQQDFLCGH PRGVSMIMNN VDENQVRVDA
260 270 280 290 300
ARAWLLPSYQ RPNLEILTGQ MVGKVLFKQT ASGPQAVGVN FGTNKAVNFD
310 320 330 340 350
VFAKHEVLLA AGSAISPLIL EYSGIGLKSV LDQANVTQLL DLPVGINMQD
360 370 380 390 400
QTTTTVSSRA SAAGAGQGQA VFFANFTETF GDYAPQAREL LNTKLDQWAE
410 420 430 440 450
ETVARGGFHN VTALKVQYEN YRNWLLDEDV AFAELFMDTE GKINFDLWDL
460 470 480 490 500
IPFTRGSVHI LSSDPYLWQF ANDPKFFLNE FDLLGQAAAS KLARDLTSQG
510 520 530 540 550
AMKEYFAGET LPGYNLVENA TLSQWSDYVL QNFRPNWHAV SSCSMMSREL
560 570 580 590 600
GGVVDATAKV YGTQGLRVID GSIPPTQVSS HVMTIFYGMA LKVADAILDD

YAKSA
Length:605
Mass (Da):65,769
Last modified:February 1, 1997 - v1
Checksum:i746F5F77FD1558D3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56240 Genomic DNA. Translation: AAB09442.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U56240 Genomic DNA. Translation: AAB09442.1.

3D structure databases

ProteinModelPortaliQ92452.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

mycoCLAPiGOX3A_TALFL.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.50.50.60. 2 hits.
4.10.450.10. 1 hit.
InterProiIPR023753. FAD/NAD-binding_dom.
IPR027424. Glucose_Oxidase_domain_2.
IPR012132. GMC_OxRdtase.
IPR000172. GMC_OxRdtase_N.
IPR007867. GMC_OxRtase_C.
[Graphical view]
PfamiPF05199. GMC_oxred_C. 1 hit.
PF00732. GMC_oxred_N. 1 hit.
[Graphical view]
PIRSFiPIRSF000137. Alcohol_oxidase. 1 hit.
SUPFAMiSSF51905. SSF51905. 2 hits.
PROSITEiPS00623. GMC_OXRED_1. 1 hit.
PS00624. GMC_OXRED_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGOX_TALFL
AccessioniPrimary (citable) accession number: Q92452
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: February 1, 1997
Last modified: October 5, 2016
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.