Q92446 (Q92446_PNECA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
P-type proton motive membrane ATPase EMBL AAB06958.1

Gene names

Name:

PCA1 EMBL AAB06958.1

Organism

Pneumocystis carinii EMBL AAB06958.1

Taxonomic identifier

4754 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Pneumocystidomycetes › Pneumocystidaceae › Pneumocystis

Protein attributes

Sequence length	927 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the cation transport ATPase (P-type) family. RuleBase RU000653

Ontologies

Keywords
Cellular component	Membrane
Domain	Transmembrane Transmembrane helix SAAS SAAS004014
Ligand	ATP-binding SAAS SAAS004014 RuleBase RU000653 Nucleotide-binding
Molecular function	Hydrolase SAAS SAAS004014 RuleBase RU000653
PTM	Phosphoprotein SAAS SAAS004014 RuleBase RU000653
Gene Ontology (GO)
Biological process	ATP biosynthetic process Inferred from electronic annotation. Source: InterPro cation transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q92446 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: 372B0466540B278A	FASTA	927	101,518
	10 20 30 40 50 60 MSEEGKALIH ETVYYKHTST FEISETTKDL EKGGEEECLL DDEDNDIEAL IDELESQGGD 70 80 90 100 110 120 QEDNIEDTEF QSQRQVPEEL LATDTRIGLT SQEVVNRRKK YGLNKMKEEK ENMIIKFLMY 130 140 150 160 170 180 FVGPIQFVME AAAILAASLQ DWVDFGVICA LLLLNAFVGF IQEFQAGSIV DELKKTLALK 190 200 210 220 230 240 ATVLRDGRLI DIEAEEVVPG DILQLEEGSI VPADGRIVTE EAYIQVDQSS ITGESLAVDK 250 260 270 280 290 300 HKGDNIYSSS VVKRGETFMV VTATGDGTFV GHAASLVNKA SCGTGHFTDV LNRIGTILLV 310 320 330 340 350 360 LVVFTLFVVY ISAFYRSSTT ITILKYTLAI TIIGVPVGLP AVVTTTMAVG AAYLAKKKAI 370 380 390 400 410 420 VQKLSAIESL AGVEILCSDK TGTLTKNDLS LAEPYTVEGI SCDELMLTAC LAASRKKKGL 430 440 450 460 470 480 DAIDKAFLKA LRNYPVVRSA ISKYNLVEFH PFDPVSKKVT AIVESPSGER IACVKGAPLF 490 500 510 520 530 540 VLRTVEEDQP VPEDIQNAYK DKVAEFASRG YRSLGIARKT GNSNWEILGI MPCSDPPRCD 550 560 570 580 590 600 TARTISEAIR LGLRIKMLTG DAVGIAKETA RQLGMGTNVY NAERLGLGGG GDMPGSEVYD 610 620 630 640 650 660 FVEAADGFAE VFPQHKYNVV EILQQRGYLV AMTGDGVNDA PSLKKADTGI AVEGASDAAR 670 680 690 700 710 720 SAADIVFLAP GLSAIIDALK TSRQIFHRMY AYVVYRIALS LHLEIFLGLW IVIFNHLMIL 730 740 750 760 770 780 ELVVFIAIFA DIATLAIAYD NAPYSLLPTK WNLPKLWGIS LLLGAALAIG SWIALTTIYI 790 800 810 820 830 840 NDNTFGIVQG YGNVDAVMFL EISLTENWLI FITRANGPFW SSLPSWQLFG AVFLVDVIAT 850 860 870 880 890 900 IFCIFGWFTG TKEHGLERTS IITVVRVWLF SLGVFCIMAG IYYLLSDSVA FDNIMHGKSV 910 920 KKNSKQRSLE DFVVALQRMS TKHEKGE

References

[1]	"PCR amplification of DNA sequences from the transcription factor IID and cation transporting ATPase genes in Pneumocystis carinii." Meade J.C., Stringer J.R. J. Protozool. 38:66S-68S(1991) [PubMed: 1840148] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[2]	"Cloning and characterization of an ATPase gene from Pneumocystis carinii which closely resembles fungal H+ ATPases." Meade J.C., Stringer J.R. J. Eukaryot. Microbiol. 42:298-307(1995) [PubMed: 7496388] [Abstract] Cited for: NUCLEOTIDE SEQUENCE.
[3]	Meade J.C., Stringer J.R. Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U65004 Genomic DNA. Translation: AAB06958.1.
3D structure databases
HSSP	HSSP built from PDB template 1MHS based on UniProtKB P07038.
ProteinModelPortal	Q92446.
SMR	Q92446. Positions 49-927.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
InterPro	IPR008250. ATPase_P-typ_ATPase-assoc-dom. IPR004014. ATPase_P-typ_cation-transptr_N. IPR023300. ATPase_P-typ_cyto_domA. IPR023299. ATPase_P-typ_cyto_domN. IPR000695. ATPase_P-typ_H-transp. IPR001757. ATPase_P-typ_ion-transptr. IPR018303. ATPase_P-typ_P_site. IPR006534. ATPase_P-typ_PM_proton-efflux. IPR023298. ATPase_P-typ_TM_dom. IPR005834. Dehalogen-like_hydro. IPR023214. HAD-like_dom. [Graphical view]
Gene3D	G3DSA:2.70.150.10. ATPase_P-typ_cyto_domA. 2 hits. G3DSA:3.40.1110.10. ATPase_P-typ_cyto_domN. 2 hits. G3DSA:1.20.1110.10. ATPase_P-typ_TM_dom. 2 hits.
PANTHER	PTHR24093:SF61. PTHR24093:SF61. 1 hit.
Pfam	PF00690. Cation_ATPase_N. 1 hit. PF00122. E1-E2_ATPase. 1 hit. PF00702. Hydrolase. 1 hit. [Graphical view]
PRINTS	PR00119. CATATPASE. PR00120. HATPASE.
SMART	SM00831. Cation_ATPase_N. 1 hit. [Graphical view]
SUPFAM	SSF56784. HAD-like_dom. 1 hit.
TIGRFAMs	TIGR01647. ATPase-IIIA_H. 1 hit. TIGR01494. ATPase_P-type. 2 hits.
PROSITE	PS00154. ATPASE_E1_E2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q92446_PNECA

Accession

Primary (citable) accession number: Q92446

Entry history

Integrated into UniProtKB/TrEMBL:	February 1, 1997
Last sequence update:	February 1, 1997
Last modified:	October 19, 2011
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)