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Protein

Plasma membrane ATPase

Gene

PCA1

Organism
Pneumocystis carinii
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + H2O + H+(In) = ADP + phosphate + H+(Out).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

HydrolaseUniRule annotation

Keywords - Biological processi

Hydrogen ion transportUniRule annotation, Ion transport, Transport

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Plasma membrane ATPaseUniRule annotation (EC:3.6.3.6UniRule annotation)
Gene namesi
Name:PCA1Imported
OrganismiPneumocystis cariniiImported
Taxonomic identifieri4754 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaPneumocystidomycetesPneumocystidaceaePneumocystis

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei117 – 136HelicalUniRule annotationAdd BLAST20
Transmembranei142 – 161HelicalUniRule annotationAdd BLAST20
Transmembranei294 – 315HelicalUniRule annotationAdd BLAST22
Transmembranei327 – 355HelicalUniRule annotationAdd BLAST29
Transmembranei689 – 713HelicalUniRule annotationAdd BLAST25
Transmembranei719 – 739HelicalUniRule annotationAdd BLAST21
Transmembranei759 – 780HelicalUniRule annotationAdd BLAST22
Transmembranei826 – 849HelicalUniRule annotationAdd BLAST24
Transmembranei861 – 885HelicalUniRule annotationAdd BLAST25

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ92446.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini68 – 141Cation_ATPase_NInterPro annotationAdd BLAST74

Sequence similaritiesi

Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIIA subfamily. [View classification]UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006534. P-type_ATPase_IIIA.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
TIGRFAMsiTIGR01647. ATPase-IIIA_H. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92446-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEEGKALIH ETVYYKHTST FEISETTKDL EKGGEEECLL DDEDNDIEAL
60 70 80 90 100
IDELESQGGD QEDNIEDTEF QSQRQVPEEL LATDTRIGLT SQEVVNRRKK
110 120 130 140 150
YGLNKMKEEK ENMIIKFLMY FVGPIQFVME AAAILAASLQ DWVDFGVICA
160 170 180 190 200
LLLLNAFVGF IQEFQAGSIV DELKKTLALK ATVLRDGRLI DIEAEEVVPG
210 220 230 240 250
DILQLEEGSI VPADGRIVTE EAYIQVDQSS ITGESLAVDK HKGDNIYSSS
260 270 280 290 300
VVKRGETFMV VTATGDGTFV GHAASLVNKA SCGTGHFTDV LNRIGTILLV
310 320 330 340 350
LVVFTLFVVY ISAFYRSSTT ITILKYTLAI TIIGVPVGLP AVVTTTMAVG
360 370 380 390 400
AAYLAKKKAI VQKLSAIESL AGVEILCSDK TGTLTKNDLS LAEPYTVEGI
410 420 430 440 450
SCDELMLTAC LAASRKKKGL DAIDKAFLKA LRNYPVVRSA ISKYNLVEFH
460 470 480 490 500
PFDPVSKKVT AIVESPSGER IACVKGAPLF VLRTVEEDQP VPEDIQNAYK
510 520 530 540 550
DKVAEFASRG YRSLGIARKT GNSNWEILGI MPCSDPPRCD TARTISEAIR
560 570 580 590 600
LGLRIKMLTG DAVGIAKETA RQLGMGTNVY NAERLGLGGG GDMPGSEVYD
610 620 630 640 650
FVEAADGFAE VFPQHKYNVV EILQQRGYLV AMTGDGVNDA PSLKKADTGI
660 670 680 690 700
AVEGASDAAR SAADIVFLAP GLSAIIDALK TSRQIFHRMY AYVVYRIALS
710 720 730 740 750
LHLEIFLGLW IVIFNHLMIL ELVVFIAIFA DIATLAIAYD NAPYSLLPTK
760 770 780 790 800
WNLPKLWGIS LLLGAALAIG SWIALTTIYI NDNTFGIVQG YGNVDAVMFL
810 820 830 840 850
EISLTENWLI FITRANGPFW SSLPSWQLFG AVFLVDVIAT IFCIFGWFTG
860 870 880 890 900
TKEHGLERTS IITVVRVWLF SLGVFCIMAG IYYLLSDSVA FDNIMHGKSV
910 920
KKNSKQRSLE DFVVALQRMS TKHEKGE
Length:927
Mass (Da):101,518
Last modified:February 1, 1997 - v1
Checksum:i372B0466540B278A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65004 Genomic DNA. Translation: AAB06958.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U65004 Genomic DNA. Translation: AAB06958.1.

3D structure databases

ProteinModelPortaliQ92446.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di1.20.1110.10. 2 hits.
2.70.150.10. 2 hits.
3.40.1110.10. 1 hit.
InterProiIPR004014. ATPase_P-typ_cation-transptr_N.
IPR023299. ATPase_P-typ_cyto_domN.
IPR018303. ATPase_P-typ_P_site.
IPR023298. ATPase_P-typ_TM_dom.
IPR008250. ATPase_P-typ_transduc_dom_A.
IPR023214. HAD-like_dom.
IPR006534. P-type_ATPase_IIIA.
IPR001757. P_typ_ATPase.
[Graphical view]
PfamiPF00690. Cation_ATPase_N. 1 hit.
PF00122. E1-E2_ATPase. 1 hit.
[Graphical view]
PRINTSiPR00120. HATPASE.
SMARTiSM00831. Cation_ATPase_N. 1 hit.
[Graphical view]
SUPFAMiSSF56784. SSF56784. 3 hits.
TIGRFAMsiTIGR01647. ATPase-IIIA_H. 1 hit.
TIGR01494. ATPase_P-type. 2 hits.
PROSITEiPS00154. ATPASE_E1_E2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ92446_PNECA
AccessioniPrimary (citable) accession number: Q92446
Entry historyi
Integrated into UniProtKB/TrEMBL: February 1, 1997
Last sequence update: February 1, 1997
Last modified: October 5, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.