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Q92442 (AGLU_MUCJA) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Alpha-glucosidase

EC=3.2.1.20
Alternative name(s):
Maltase
OrganismMucor javanicus
Taxonomic identifier51122 [NCBI]
Taxonomic lineageEukaryotaFungiFungi incertae sedisEarly diverging fungal lineagesMucoromycotinaMucoralesMucorineaeMucoraceaeMucor

Protein attributes

Sequence length864 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Hydrolyzes not only malto-oligosaccharides but also soluble starch.

Catalytic activity

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 31 family.

Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular_functioncarbohydrate binding

Inferred from electronic annotation. Source: InterPro

maltose alpha-glucosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 864842Alpha-glucosidase
PRO_0000018580

Sites

Active site4301Nucleophile By similarity
Active site4331 By similarity
Active site5671Proton donor By similarity

Amino acid modifications

Glycosylation1871N-linked (GlcNAc...) Potential
Glycosylation3641N-linked (GlcNAc...) Potential
Glycosylation4061N-linked (GlcNAc...) Potential
Glycosylation4661N-linked (GlcNAc...) Potential
Glycosylation5001N-linked (GlcNAc...) Potential
Glycosylation5681N-linked (GlcNAc...) Potential
Glycosylation7341N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
Q92442 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: CFAB4759DC431403

FASTA86498,761
        10         20         30         40         50         60 
MAKVSFIFVA IALITGNVLC QTDATYAVSS SAPGYKIDGH VRKTEAGLHI PLTLNSRGNK 

        70         80         90        100        110        120 
KTGIDTFGKT IKDITVDVEY ETEERLHVKI SDKAKKQYLV PDSPLGFERP QIKHYVSPKH 

       130        140        150        160        170        180 
SNLDFQYTAK PFSFKVVRKD DKTTIFDTTN MPLVFEDQYL ELSTKVPEDA NIYGIGEVTA 

       190        200        210        220        230        240 
PFRRTHNVTT LWARDNPDDF YRNIYGAHPY YQEVRDGKAH GALLMNAHGM DVITTEGRIT 

       250        260        270        280        290        300 
YKVIGGILDF YFFAPKSGKP NDLSIAYTDL IGKPMMPSHW MLGWHHCRYG YPNIDKVETV 

       310        320        330        340        350        360 
KRKYKEANIP LQTVWVDIDY MEETKDFTFD KVNFPQDRMI GLGEQLHKDG QNYVVMVDPA 

       370        380        390        400        410        420 
ISANTTYEPY VRGTEMDVWI KNADGSDFIG SVWPGFTTFP DWWHPNATKY WNKEIIDFVD 

       430        440        450        460        470        480 
MLGVDGLWID MNEPASFCLG SCGSGKVDAG NQPYRWTYTE EEQAANHTRW EKELKAMGNP 

       490        500        510        520        530        540 
PGEERNLLYP KYAINNGAGN LSEFTVATTA LHYGNIPHYD IHNLYGHAES HITRQALIKH 

       550        560        570        580        590        600 
KNKIRPFVLT RSSFPGSGKS VGHWTGDNHS FWPYLKNSIA NILNFQMFGV SYSGADVCGF 

       610        620        630        640        650        660 
NSDTTEELCT RWMEIGAFYP FARNHNNNAA KDQEPYLWES TAEASRIAIN TRYEMLPYFY 

       670        680        690        700        710        720 
TLFEESNRLG LGVWRPLIFE YPAYEELVSN DVQTLVGSDI LLSPVLDEGK TSVKAQFPGG 

       730        740        750        760        770        780 
QWYDWYTHEL TVDNKSNKKV KTVTLDAPLT HIPIHIRGGA IIPTKTPKYT VGETFATPYN 

       790        800        810        820        830        840 
LVIALDKKGQ ASGRLYIDDG ESLEVKSSSG YHFHLQEWSP QGFWQVWLQE GRKDWLHHHY 

       850        860 
WQARQQVAKG SRWQEDYQID PWQE 

« Hide

References

[1]"Molecular cloning, sequencing, and expression of a cDNA encoding alpha-glucosidase from Mucor javanicus."
Sugimoto M., Suzuki Y.
J. Biochem. 119:500-505(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], PARTIAL PROTEIN SEQUENCE.
Strain: DSM 1222 / NBRC 4570 / NRRL 13035.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D67034 mRNA. Translation: BAA11053.1.

3D structure databases

ProteinModelPortalQ92442.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH31. Glycoside Hydrolase Family 31.
mycoCLAPAGL31A_MUCJA.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAGLU_MUCJA
AccessionPrimary (citable) accession number: Q92442
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: October 16, 2013
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries