Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Alpha-glucosidase

Gene
N/A
Organism
Mucor javanicus
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Hydrolyzes not only malto-oligosaccharides but also soluble starch.

Catalytic activityi

Hydrolysis of terminal, non-reducing (1->4)-linked alpha-D-glucose residues with release of alpha-D-glucose.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei430NucleophilePROSITE-ProRule annotation1
Active sitei433By similarity1
Active sitei567Proton donorBy similarity1

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.
mycoCLAPiAGL31A_MUCJA.

Names & Taxonomyi

Protein namesi
Recommended name:
Alpha-glucosidase (EC:3.2.1.20)
Alternative name(s):
Maltase
OrganismiMucor javanicus
Taxonomic identifieri51122 [NCBI]
Taxonomic lineageiEukaryotaFungiFungi incertae sedisMucoromycotinaMucoralesMucorineaeMucoraceaeMucor

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 22Sequence analysisAdd BLAST22
ChainiPRO_000001858023 – 864Alpha-glucosidaseAdd BLAST842

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi187N-linked (GlcNAc...)Sequence analysis1
Glycosylationi364N-linked (GlcNAc...)Sequence analysis1
Glycosylationi406N-linked (GlcNAc...)Sequence analysis1
Glycosylationi466N-linked (GlcNAc...)Sequence analysis1
Glycosylationi500N-linked (GlcNAc...)Sequence analysis1
Glycosylationi568N-linked (GlcNAc...)Sequence analysis1
Glycosylationi734N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Structurei

3D structure databases

ProteinModelPortaliQ92442.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyl hydrolase 31 family.Curated

Keywords - Domaini

Signal

Family and domain databases

InterProiIPR031727. Gal_mutarotase_N.
IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR030458. Glyco_hydro_31_AS.
IPR030459. Glyco_hydro_31_CS.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
PF16863. NtCtMGAM_N. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q92442-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKVSFIFVA IALITGNVLC QTDATYAVSS SAPGYKIDGH VRKTEAGLHI
60 70 80 90 100
PLTLNSRGNK KTGIDTFGKT IKDITVDVEY ETEERLHVKI SDKAKKQYLV
110 120 130 140 150
PDSPLGFERP QIKHYVSPKH SNLDFQYTAK PFSFKVVRKD DKTTIFDTTN
160 170 180 190 200
MPLVFEDQYL ELSTKVPEDA NIYGIGEVTA PFRRTHNVTT LWARDNPDDF
210 220 230 240 250
YRNIYGAHPY YQEVRDGKAH GALLMNAHGM DVITTEGRIT YKVIGGILDF
260 270 280 290 300
YFFAPKSGKP NDLSIAYTDL IGKPMMPSHW MLGWHHCRYG YPNIDKVETV
310 320 330 340 350
KRKYKEANIP LQTVWVDIDY MEETKDFTFD KVNFPQDRMI GLGEQLHKDG
360 370 380 390 400
QNYVVMVDPA ISANTTYEPY VRGTEMDVWI KNADGSDFIG SVWPGFTTFP
410 420 430 440 450
DWWHPNATKY WNKEIIDFVD MLGVDGLWID MNEPASFCLG SCGSGKVDAG
460 470 480 490 500
NQPYRWTYTE EEQAANHTRW EKELKAMGNP PGEERNLLYP KYAINNGAGN
510 520 530 540 550
LSEFTVATTA LHYGNIPHYD IHNLYGHAES HITRQALIKH KNKIRPFVLT
560 570 580 590 600
RSSFPGSGKS VGHWTGDNHS FWPYLKNSIA NILNFQMFGV SYSGADVCGF
610 620 630 640 650
NSDTTEELCT RWMEIGAFYP FARNHNNNAA KDQEPYLWES TAEASRIAIN
660 670 680 690 700
TRYEMLPYFY TLFEESNRLG LGVWRPLIFE YPAYEELVSN DVQTLVGSDI
710 720 730 740 750
LLSPVLDEGK TSVKAQFPGG QWYDWYTHEL TVDNKSNKKV KTVTLDAPLT
760 770 780 790 800
HIPIHIRGGA IIPTKTPKYT VGETFATPYN LVIALDKKGQ ASGRLYIDDG
810 820 830 840 850
ESLEVKSSSG YHFHLQEWSP QGFWQVWLQE GRKDWLHHHY WQARQQVAKG
860
SRWQEDYQID PWQE
Length:864
Mass (Da):98,761
Last modified:February 1, 1997 - v1
Checksum:iCFAB4759DC431403
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D67034 mRNA. Translation: BAA11053.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D67034 mRNA. Translation: BAA11053.1.

3D structure databases

ProteinModelPortaliQ92442.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

CAZyiGH31. Glycoside Hydrolase Family 31.
mycoCLAPiAGL31A_MUCJA.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiIPR031727. Gal_mutarotase_N.
IPR011013. Gal_mutarotase_SF_dom.
IPR000322. Glyco_hydro_31.
IPR030458. Glyco_hydro_31_AS.
IPR030459. Glyco_hydro_31_CS.
IPR025887. Glyco_hydro_31_N_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF13802. Gal_mutarotas_2. 1 hit.
PF01055. Glyco_hydro_31. 1 hit.
PF16863. NtCtMGAM_N. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF74650. SSF74650. 1 hit.
PROSITEiPS00129. GLYCOSYL_HYDROL_F31_1. 1 hit.
PS00707. GLYCOSYL_HYDROL_F31_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAGLU_MUCJA
AccessioniPrimary (citable) accession number: Q92442
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: September 7, 2016
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Direct protein sequencing

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.