Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

StAR-related lipid transfer protein 13

Gene

Stard13

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

May function as a GTPase-activating protein.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Biological processi

Cell cycle

Enzyme and pathway databases

ReactomeiREACT_297947. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Recommended name:
StAR-related lipid transfer protein 13
Alternative name(s):
START domain-containing protein 13
Short name:
StARD13
Gene namesi
Name:Stard13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:2385331. Stard13.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Lipid droplet, Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11131113StAR-related lipid transfer protein 13PRO_0000220680Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineBy similarity
Modified residuei133 – 1331Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ923Q2.
PaxDbiQ923Q2.
PRIDEiQ923Q2.

PTM databases

PhosphoSiteiQ923Q2.

Expressioni

Gene expression databases

BgeeiQ923Q2.
ExpressionAtlasiQ923Q2. baseline and differential.
GenevisibleiQ923Q2. MM.

Interactioni

Subunit structurei

Homodimer. Interacts with TAX1BP1 (By similarity).By similarity

Protein-protein interaction databases

IntActiQ923Q2. 1 interaction.
MINTiMINT-4135694.
STRINGi10090.ENSMUSP00000053232.

Structurei

3D structure databases

ProteinModelPortaliQ923Q2.
SMRiQ923Q2. Positions 50-120, 655-863, 907-1104.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 12268SAMAdd
BLAST
Domaini663 – 868206Rho-GAPPROSITE-ProRule annotationAdd
BLAST
Domaini899 – 1109211STARTPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 Rho-GAP domain.PROSITE-ProRule annotation
Contains 1 START domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiNOG236923.
GeneTreeiENSGT00760000119123.
HOGENOMiHOG000039960.
HOVERGENiHBG055955.
InParanoidiQ923Q2.
OrthoDBiEOG7CG6Z8.
PhylomeDBiQ923Q2.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
3.30.530.20. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR013761. SAM/pointed.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
SM00234. START. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS50848. START. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q923Q2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFSQVPRTPA AGCYYLNPLT PESQEMYLRF DQTARRSPYR MSRILARHHL
60 70 80 90 100
VTKIQQEIEA KEACDWLRAA GFPQYAQLYE DSQFPINIAA VKKDHDFLER
110 120 130 140 150
DLVEPLCRRL NTLNKCASMR LDVNFQRKKG DDSDEEDLCI SNKWTFQRTS
160 170 180 190 200
RRWSRVDDLH TLFPVADRNG SPGGPRMRNT ASSESVLTDL SEPEVCSIHS
210 220 230 240 250
ESSGGSDSRS QSGHHSADST HALEATLVSS SLPQSTREGL NQSFHPKNEK
260 270 280 290 300
PTRTRAKSFL KRMDTLRVKG ALGRHKGPGR TGGLVISRPV LQQEPESFKT
310 320 330 340 350
MQCVQIPNGD LQTSPPAACR KGLPCSSKSS GESSPLENSS TVSTPCMKER
360 370 380 390 400
KCHHEANKRG GMYLEDLDVL AGTALPDTSD QNHMHGFHSQ ENLVVHIPKD
410 420 430 440 450
HKPGTFPKAL SIESLSPTDN SNGVNWRTGS ISLGRQQGPG MREPRLMSSC
460 470 480 490 500
HRASRVSIYD NVPSSHLYAS TGDLLDLEKD GLLPQLDDIL QHVNGIQEVV
510 520 530 540 550
DDWSKNILPE LQSHSTLAGD PGLSPFPSPN QVTLDFEGNS VSEGRTTPSD
560 570 580 590 600
VERDRTSLNE SEATGVRERR DSGVGASLTR PNRRLRWSSF QLSHQPQPSP
610 620 630 640 650
ATPHISSQTA AQLNLLQRFS LLRLTAIMEK YSMSNKHGWT WSVPKFMKRI
660 670 680 690 700
KAPDYRDKAV FGVPLIVHVQ RTGQPLPQSI QQALRYLRSN CLDQVGLFRK
710 720 730 740 750
SGVKSRIHAL RQMNENFPDN VSYEDQSAYD VADMVKQFFR DLPEPLFTNK
760 770 780 790 800
LSETFLHIYQ YVPKEQRLQA VQAAILLLAD ENREALQTLL CFLHDVVNLV
810 820 830 840 850
DENQMTPMNL AVCLAPSLFH LNLLKKESSP KVIQKKYATG KPDQKDLNEN
860 870 880 890 900
LAAAQGLAHM ITECNRLFEV PHEMVAQSRD SYLEAEIHVP SLEDLGAQLA
910 920 930 940 950
ESGATFHTYL EHLVQGLQKE AKEKFKGWVT CSSPDNTDLA FKKVGDGHPL
960 970 980 990 1000
KLWKASVEVE APPSVVLNRV LRERHLWDED FVQWKVVERL DKQTEIYQYV
1010 1020 1030 1040 1050
LNSMVPHPSR DFLVLRTWKT DLPKGMCTLV SLSVEYEEAQ LMGGVRAVVM
1060 1070 1080 1090 1100
DSQYLIEPCG SGKSRLTHIC RIDLKGHSPE WYSKGFGHLC AAEVTRIRNS
1110
FQPLVAEGPE TKI
Length:1,113
Mass (Da):125,060
Last modified:July 27, 2011 - v5
Checksum:iA516D16FFA327E74
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti384 – 3841M → V in AAH27830 (PubMed:15489334).Curated
Sequence conflicti785 – 7851A → V in AAH27830 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109614 Genomic DNA. No translation available.
AC163219 Genomic DNA. No translation available.
BC027830 mRNA. Translation: AAH27830.2.
CCDSiCCDS19890.1.
RefSeqiNP_666370.3. NM_146258.2.
UniGeneiMm.209272.

Genome annotation databases

EnsembliENSMUST00000110483; ENSMUSP00000106109; ENSMUSG00000016128.
GeneIDi243362.
KEGGimmu:243362.
UCSCiuc009aum.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC109614 Genomic DNA. No translation available.
AC163219 Genomic DNA. No translation available.
BC027830 mRNA. Translation: AAH27830.2.
CCDSiCCDS19890.1.
RefSeqiNP_666370.3. NM_146258.2.
UniGeneiMm.209272.

3D structure databases

ProteinModelPortaliQ923Q2.
SMRiQ923Q2. Positions 50-120, 655-863, 907-1104.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ923Q2. 1 interaction.
MINTiMINT-4135694.
STRINGi10090.ENSMUSP00000053232.

PTM databases

PhosphoSiteiQ923Q2.

Proteomic databases

MaxQBiQ923Q2.
PaxDbiQ923Q2.
PRIDEiQ923Q2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000110483; ENSMUSP00000106109; ENSMUSG00000016128.
GeneIDi243362.
KEGGimmu:243362.
UCSCiuc009aum.2. mouse.

Organism-specific databases

CTDi90627.
MGIiMGI:2385331. Stard13.

Phylogenomic databases

eggNOGiNOG236923.
GeneTreeiENSGT00760000119123.
HOGENOMiHOG000039960.
HOVERGENiHBG055955.
InParanoidiQ923Q2.
OrthoDBiEOG7CG6Z8.
PhylomeDBiQ923Q2.

Enzyme and pathway databases

ReactomeiREACT_297947. Rho GTPase cycle.

Miscellaneous databases

ChiTaRSiStard13. mouse.
NextBioi385731.
PROiQ923Q2.
SOURCEiSearch...

Gene expression databases

BgeeiQ923Q2.
ExpressionAtlasiQ923Q2. baseline and differential.
GenevisibleiQ923Q2. MM.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
3.30.530.20. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR013761. SAM/pointed.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
SM00234. START. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS50848. START. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Mammary tumor.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-133, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiSTA13_MOUSE
AccessioniPrimary (citable) accession number: Q923Q2
Secondary accession number(s): E9PUB5, Q8K369
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: July 27, 2011
Last modified: June 24, 2015
This is version 112 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.