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Q923Q2

- STA13_MOUSE

UniProt

Q923Q2 - STA13_MOUSE

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Protein
StAR-related lipid transfer protein 13
Gene
Stard13
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5 - Experimental evidence at protein leveli

Functioni

May function as a GTPase-activating protein.

GO - Molecular functioni

  1. GTPase activator activity Source: UniProtKB-KW
  2. lipid binding Source: InterPro

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. signal transduction Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GTPase activation

Keywords - Biological processi

Cell cycle

Enzyme and pathway databases

ReactomeiREACT_210090. Rho GTPase cycle.

Names & Taxonomyi

Protein namesi
Recommended name:
StAR-related lipid transfer protein 13
Alternative name(s):
START domain-containing protein 13
Short name:
StARD13
Gene namesi
Name:Stard13
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 5

Organism-specific databases

MGIiMGI:2385331. Stard13.

Subcellular locationi

GO - Cellular componenti

  1. lipid particle Source: UniProtKB-SubCell
  2. mitochondrial membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Lipid droplet, Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 11131113StAR-related lipid transfer protein 13
PRO_0000220680Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionine By similarity
Modified residuei133 – 1331Phosphoserine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ923Q2.
PRIDEiQ923Q2.

PTM databases

PhosphoSiteiQ923Q2.

Expressioni

Gene expression databases

ArrayExpressiQ923Q2.
BgeeiQ923Q2.
GenevestigatoriQ923Q2.

Interactioni

Subunit structurei

Homodimer. Interacts with TAX1BP1 By similarity.

Protein-protein interaction databases

IntActiQ923Q2. 1 interaction.
MINTiMINT-4135694.

Structurei

3D structure databases

ProteinModelPortaliQ923Q2.
SMRiQ923Q2. Positions 50-120, 655-863, 907-1104.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 12268SAM
Add
BLAST
Domaini663 – 868206Rho-GAP
Add
BLAST
Domaini899 – 1109211START
Add
BLAST

Sequence similaritiesi

Contains 1 Rho-GAP domain.
Contains 1 START domain.

Phylogenomic databases

eggNOGiNOG236923.
GeneTreeiENSGT00740000115136.
HOGENOMiHOG000039960.
HOVERGENiHBG055955.
OrthoDBiEOG7CG6Z8.
PhylomeDBiQ923Q2.

Family and domain databases

Gene3Di1.10.555.10. 1 hit.
3.30.530.20. 1 hit.
InterProiIPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR013761. SAM/pointed.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view]
PfamiPF00620. RhoGAP. 1 hit.
PF01852. START. 1 hit.
[Graphical view]
SMARTiSM00324. RhoGAP. 1 hit.
SM00234. START. 1 hit.
[Graphical view]
SUPFAMiSSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
PROSITEiPS50238. RHOGAP. 1 hit.
PS50848. START. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q923Q2-1 [UniParc]FASTAAdd to Basket

« Hide

MFSQVPRTPA AGCYYLNPLT PESQEMYLRF DQTARRSPYR MSRILARHHL     50
VTKIQQEIEA KEACDWLRAA GFPQYAQLYE DSQFPINIAA VKKDHDFLER 100
DLVEPLCRRL NTLNKCASMR LDVNFQRKKG DDSDEEDLCI SNKWTFQRTS 150
RRWSRVDDLH TLFPVADRNG SPGGPRMRNT ASSESVLTDL SEPEVCSIHS 200
ESSGGSDSRS QSGHHSADST HALEATLVSS SLPQSTREGL NQSFHPKNEK 250
PTRTRAKSFL KRMDTLRVKG ALGRHKGPGR TGGLVISRPV LQQEPESFKT 300
MQCVQIPNGD LQTSPPAACR KGLPCSSKSS GESSPLENSS TVSTPCMKER 350
KCHHEANKRG GMYLEDLDVL AGTALPDTSD QNHMHGFHSQ ENLVVHIPKD 400
HKPGTFPKAL SIESLSPTDN SNGVNWRTGS ISLGRQQGPG MREPRLMSSC 450
HRASRVSIYD NVPSSHLYAS TGDLLDLEKD GLLPQLDDIL QHVNGIQEVV 500
DDWSKNILPE LQSHSTLAGD PGLSPFPSPN QVTLDFEGNS VSEGRTTPSD 550
VERDRTSLNE SEATGVRERR DSGVGASLTR PNRRLRWSSF QLSHQPQPSP 600
ATPHISSQTA AQLNLLQRFS LLRLTAIMEK YSMSNKHGWT WSVPKFMKRI 650
KAPDYRDKAV FGVPLIVHVQ RTGQPLPQSI QQALRYLRSN CLDQVGLFRK 700
SGVKSRIHAL RQMNENFPDN VSYEDQSAYD VADMVKQFFR DLPEPLFTNK 750
LSETFLHIYQ YVPKEQRLQA VQAAILLLAD ENREALQTLL CFLHDVVNLV 800
DENQMTPMNL AVCLAPSLFH LNLLKKESSP KVIQKKYATG KPDQKDLNEN 850
LAAAQGLAHM ITECNRLFEV PHEMVAQSRD SYLEAEIHVP SLEDLGAQLA 900
ESGATFHTYL EHLVQGLQKE AKEKFKGWVT CSSPDNTDLA FKKVGDGHPL 950
KLWKASVEVE APPSVVLNRV LRERHLWDED FVQWKVVERL DKQTEIYQYV 1000
LNSMVPHPSR DFLVLRTWKT DLPKGMCTLV SLSVEYEEAQ LMGGVRAVVM 1050
DSQYLIEPCG SGKSRLTHIC RIDLKGHSPE WYSKGFGHLC AAEVTRIRNS 1100
FQPLVAEGPE TKI 1113
Length:1,113
Mass (Da):125,060
Last modified:July 27, 2011 - v5
Checksum:iA516D16FFA327E74
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti384 – 3841M → V in AAH27830. 1 Publication
Sequence conflicti785 – 7851A → V in AAH27830. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC109614 Genomic DNA. No translation available.
AC163219 Genomic DNA. No translation available.
BC027830 mRNA. Translation: AAH27830.2.
CCDSiCCDS19890.1.
RefSeqiNP_666370.3. NM_146258.2.
UniGeneiMm.209272.

Genome annotation databases

EnsembliENSMUST00000110483; ENSMUSP00000106109; ENSMUSG00000016128.
GeneIDi243362.
KEGGimmu:243362.
UCSCiuc009aum.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC109614 Genomic DNA. No translation available.
AC163219 Genomic DNA. No translation available.
BC027830 mRNA. Translation: AAH27830.2 .
CCDSi CCDS19890.1.
RefSeqi NP_666370.3. NM_146258.2.
UniGenei Mm.209272.

3D structure databases

ProteinModelPortali Q923Q2.
SMRi Q923Q2. Positions 50-120, 655-863, 907-1104.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

IntActi Q923Q2. 1 interaction.
MINTi MINT-4135694.

PTM databases

PhosphoSitei Q923Q2.

Proteomic databases

PaxDbi Q923Q2.
PRIDEi Q923Q2.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000110483 ; ENSMUSP00000106109 ; ENSMUSG00000016128 .
GeneIDi 243362.
KEGGi mmu:243362.
UCSCi uc009aum.2. mouse.

Organism-specific databases

CTDi 90627.
MGIi MGI:2385331. Stard13.

Phylogenomic databases

eggNOGi NOG236923.
GeneTreei ENSGT00740000115136.
HOGENOMi HOG000039960.
HOVERGENi HBG055955.
OrthoDBi EOG7CG6Z8.
PhylomeDBi Q923Q2.

Enzyme and pathway databases

Reactomei REACT_210090. Rho GTPase cycle.

Miscellaneous databases

ChiTaRSi STARD13. mouse.
NextBioi 385731.
PROi Q923Q2.
SOURCEi Search...

Gene expression databases

ArrayExpressi Q923Q2.
Bgeei Q923Q2.
Genevestigatori Q923Q2.

Family and domain databases

Gene3Di 1.10.555.10. 1 hit.
3.30.530.20. 1 hit.
InterProi IPR008936. Rho_GTPase_activation_prot.
IPR000198. RhoGAP_dom.
IPR013761. SAM/pointed.
IPR023393. START-like_dom.
IPR002913. START_lipid-bd_dom.
[Graphical view ]
Pfami PF00620. RhoGAP. 1 hit.
PF01852. START. 1 hit.
[Graphical view ]
SMARTi SM00324. RhoGAP. 1 hit.
SM00234. START. 1 hit.
[Graphical view ]
SUPFAMi SSF47769. SSF47769. 1 hit.
SSF48350. SSF48350. 1 hit.
PROSITEi PS50238. RHOGAP. 1 hit.
PS50848. START. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Mammary tumor.
  3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-133, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.

Entry informationi

Entry nameiSTA13_MOUSE
AccessioniPrimary (citable) accession number: Q923Q2
Secondary accession number(s): E9PUB5, Q8K369
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 15, 2002
Last sequence update: July 27, 2011
Last modified: September 3, 2014
This is version 105 of the entry and version 5 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi