Unreviewed, UniProtKB/TrEMBL Q923H0 (Q923H0_MOUSE)

Names and origin

Protein names

Submitted name:
    F-box/WD40 repeat-containing protein HOS EMBL AAK72095.1

Gene names

Name:	Fbxw11 MGI 2144023
Synonyms:	Fbxw1b MGI 2144023

Organism

Mus musculus (Mouse) EMBL AAK72095.1

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	563 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Contains 1 F-box domain.

Ontologies

Keywords
Domain	Repeat RuleBase RU003532V3 WD repeat RuleBase RU000362V4
Gene Ontology (GO)
Molecular function	protein binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q923H0-1 [UniParc]. Last modified December 1, 2001. Version 1. Checksum: 9AB562F3FF5E3496	FASTA	563	64,742
	10 20 30 40 50 60 MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQN TSVMEDQNED 70 80 90 100 110 120 ESPKKSALWQ ISNGTSSVIV SRKRPSEGNY QKEKDLCIKY FDQWSESDQV EFVEHLISRM 130 140 150 160 170 180 CHYQHGHINS YLKPMLQRDF ITALPEQGLD HIAENILSYL DARSLCAAEL VCKEWQRVIS 190 200 210 220 230 240 EGMLWKKLIE RMVRTDPLWK GLSERRGWDQ YLFKNRPTDG PPNSFYRSLY PKIIQDIETI 250 260 270 280 290 300 ESNWRCGRHN LQRIQCRSEN SKGVYCLQYD DDKIISGLRD NSIKIWDKSS LECLKVLTGH 310 320 330 340 350 360 TGSVLCLQYD ERVIVTGSSD STVRVWDVNT GEVLNTLIHH NEAVLHLRFS NGLMVTCSKD 370 380 390 400 410 420 RSIAVWDMAF CHRYHFTPCS GWPRAAVNVV DFDDKYIVSA SGDRTIKVWS TSTCEFVRTL 430 440 450 460 470 480 NGHKRGIACL QYRDRLVVSG SSDNTIRLWD IECGACLRVL EGHEELVRCI RFDNKRIVSG 490 500 510 520 530 540 AYDGKIKVWD LQAALDPRAP ASTLCLRTLV EHSGRVFRLQ FDEFQIISSS HDDTILIWDF 550 560 LNVPPSAQNE TRSPFRTYTY ISR

References

[1]	"Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB." Bhatia N., Herter J.R., Slaga T.J., Fuchs S.Y., Spiegelman V.S. Oncogene 21:1501-1509(2002) [PubMed: 11896578] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: FVB/N EMBL AAK72095.1.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY038079 mRNA. Translation: AAK72095.1.
IPI	IPI00473301.
UniGene	Mm.28017
3D structure databases
HSSP	HSSP built from PDB template 1P22 based on UniProtKB Q9Y297.
SMR	Q923H0. Positions 88-137, 135-539.
ModBase	Search...
Protein-protein interaction databases
STRING	Q923H0.
Genome annotation databases
Ensembl	ENSMUST00000076383; ENSMUSP00000075721; ENSMUSG00000020271; Mus musculus. [Genome view]
Organism-specific databases
MGI	MGI:2144023. Fbxw11.
Phylogenomic databases
HOVERGEN	Q923H0.
InParanoid	Q923H0.
Gene expression databases
ArrayExpress	Q923H0.
Bgee	Q923H0.
Genevestigator	Q923H0.
Family and domain databases
InterPro	IPR001810. F-box. IPR020472. G-protein_beta_WD-40_rep_reg. IPR015943. WD40/YVTN_repeat-like_dom. IPR001680. WD40_repeat. IPR011046. WD40_repeat-like_dom. IPR019782. WD40_repeat_2. IPR019775. WD40_repeat_CS. IPR017986. WD40_repeat_dom. IPR019781. WD40_repeat_sg. [Graphical view]
Gene3D	G3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
Pfam	PF00646. F-box. 1 hit. PF00400. WD40. 7 hits. [Graphical view]
PRINTS	PR00320. GPROTEINBRPT.
SMART	SM00256. FBOX. 1 hit. SM00320. WD40. 7 hits. [Graphical view]
PROSITE	PS50181. FBOX. 1 hit. PS00678. WD_REPEATS_1. 5 hits. PS50082. WD_REPEATS_2. 7 hits. PS50294. WD_REPEATS_REGION. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
SOURCE	Search...

Entry information

Entry name

Q923H0_MOUSE

Accession

Primary (citable) accession number: Q923H0

Entry history

Integrated into UniProtKB/TrEMBL:	December 1, 2001
Last sequence update:	December 1, 2001
Last modified:	January 19, 2010
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)