Skip Header

Contribute Send feedback
Read comments (0) or add your own

Unreviewed, UniProtKB/TrEMBL Q923H0 (Q923H0_MOUSE)

Last modified January 19, 2010. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

Hide | Top

Names and origin

Protein namesSubmitted name:
    F-box/WD40 repeat-containing protein HOS EMBL AAK72095.1
Gene names
Name: Fbxw11 MGI 2144023
Synonyms: Fbxw1b MGI 2144023
OrganismMus musculus (Mouse) EMBL AAK72095.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Hide | Top

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

Hide | Top

General annotation (Comments)

Sequence similarities

Contains 1 F-box domain.

Hide | Top

Ontologies

Keywords
   DomainRepeat RuleBase RU003532V3
WD repeat RuleBase RU000362V4
Gene Ontology (GO)
   Molecular functionprotein binding

Inferred from electronic annotation. Source: Compara

Complete GO annotation...

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q923H0-1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 9AB562F3FF5E3496

FASTA56364,742
        10         20         30         40         50         60 
MEPDSVIEDK TIELMCSVPR SLWLGCANLV ESMCALSCLQ SMPSVRCLQN TSVMEDQNED 

        70         80         90        100        110        120 
ESPKKSALWQ ISNGTSSVIV SRKRPSEGNY QKEKDLCIKY FDQWSESDQV EFVEHLISRM 

       130        140        150        160        170        180 
CHYQHGHINS YLKPMLQRDF ITALPEQGLD HIAENILSYL DARSLCAAEL VCKEWQRVIS 

       190        200        210        220        230        240 
EGMLWKKLIE RMVRTDPLWK GLSERRGWDQ YLFKNRPTDG PPNSFYRSLY PKIIQDIETI 

       250        260        270        280        290        300 
ESNWRCGRHN LQRIQCRSEN SKGVYCLQYD DDKIISGLRD NSIKIWDKSS LECLKVLTGH 

       310        320        330        340        350        360 
TGSVLCLQYD ERVIVTGSSD STVRVWDVNT GEVLNTLIHH NEAVLHLRFS NGLMVTCSKD 

       370        380        390        400        410        420 
RSIAVWDMAF CHRYHFTPCS GWPRAAVNVV DFDDKYIVSA SGDRTIKVWS TSTCEFVRTL 

       430        440        450        460        470        480 
NGHKRGIACL QYRDRLVVSG SSDNTIRLWD IECGACLRVL EGHEELVRCI RFDNKRIVSG 

       490        500        510        520        530        540 
AYDGKIKVWD LQAALDPRAP ASTLCLRTLV EHSGRVFRLQ FDEFQIISSS HDDTILIWDF 

       550        560 
LNVPPSAQNE TRSPFRTYTY ISR

« Hide

Hide | Top

References

[1]"Mouse homologue of HOS (mHOS) is overexpressed in skin tumors and implicated in constitutive activation of NF-kappaB."
Bhatia N., Herter J.R., Slaga T.J., Fuchs S.Y., Spiegelman V.S.
Oncogene 21:1501-1509(2002) [PubMed: 11896578] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: FVB/N EMBL AAK72095.1.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AY038079 mRNA. Translation: AAK72095.1.
IPIIPI00473301.
UniGeneMm.28017

3D structure databases

HSSPHSSP built from PDB template 1P22 based on UniProtKB Q9Y297.
SMRQ923H0. Positions 88-137, 135-539.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ923H0.

Genome annotation databases

EnsemblENSMUST00000076383; ENSMUSP00000075721; ENSMUSG00000020271; Mus musculus. [Genome view]

Organism-specific databases

MGIMGI:2144023. Fbxw11.

Phylogenomic databases

HOVERGENQ923H0.
InParanoidQ923H0.

Gene expression databases

ArrayExpressQ923H0.
BgeeQ923H0.
GenevestigatorQ923H0.

Family and domain databases

InterProIPR001810. F-box.
IPR020472. G-protein_beta_WD-40_rep_reg.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR011046. WD40_repeat-like_dom.
IPR019782. WD40_repeat_2.
IPR019775. WD40_repeat_CS.
IPR017986. WD40_repeat_dom.
IPR019781. WD40_repeat_sg.
[Graphical view]
Gene3DG3DSA:2.130.10.10. WD40/YVTN_repeat-like. 1 hit.
PfamPF00646. F-box. 1 hit.
PF00400. WD40. 7 hits.
[Graphical view]
PRINTSPR00320. GPROTEINBRPT.
SMARTSM00256. FBOX. 1 hit.
SM00320. WD40. 7 hits.
[Graphical view]
PROSITEPS50181. FBOX. 1 hit.
PS00678. WD_REPEATS_1. 5 hits.
PS50082. WD_REPEATS_2. 7 hits.
PS50294. WD_REPEATS_REGION. 1 hit.
[Graphical view]
ProtoNetSearch...

Other Resources

SOURCESearch...

Hide | Top

Entry information

Entry nameQ923H0_MOUSE
AccessionPrimary (citable) accession number: Q923H0
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: January 19, 2010
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information