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Q92367 (AAP1_SCHPO) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Amino-acid permease 1
Gene names
Name:aap1
ORF Names:SPBC1652.02, SPBC16A3.20c
OrganismSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifier284812 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length594 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Probable.

Sequence similarities

Belongs to the amino acid-polyamine-organocation (APC) superfamily.

Ontologies

Keywords
   Biological processAmino-acid transport
Transport
   Cellular componentMembrane
   DomainTransmembrane
Transmembrane helix
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular componentendoplasmic reticulum

Inferred from direct assay. Source: GeneDB_Spombe

integral to membrane

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionamino acid transmembrane transporter activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 594594Amino-acid permease 1
PRO_0000054166

Regions

Transmembrane75 – 9521Helical; Potential
Transmembrane101 – 12121Helical; Potential
Transmembrane146 – 16621Helical; Potential
Transmembrane181 – 20121Helical; Potential
Transmembrane210 – 23021Helical; Potential
Transmembrane297 – 31721Helical; Potential
Transmembrane323 – 34321Helical; Potential
Transmembrane344 – 36421Helical; Potential
Transmembrane390 – 41021Helical; Potential
Transmembrane416 – 43621Helical; Potential
Transmembrane468 – 48821Helical; Potential
Transmembrane498 – 51821Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q92367 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 0072DD039BEFB901

FASTA59465,278
        10         20         30         40         50         60 
MTSFTESKKL DEIESPVPEI IVPSTTNGNG TIESYKEKSV GTSFLDFFRS YKLRPDNEFA 

        70         80         90        100        110        120 
EVHNSEDFLK PRHLQMIAIG SCIGTGLFVS TGKSLKNAGP GSLMINFIIL SAMILALILS 

       130        140        150        160        170        180 
LGEMCCFLPN QSSITMYTGR LLNNNIGFAQ SWLYFWIWLT VLPSEISAAC EVVDFWTTQH 

       190        200        210        220        230        240 
LNPAIWVTIF LAYVVLVNAF GARSYGECEF VSSFLKVVIV IIFFFVAIII NCGAAPKGGY 

       250        260        270        280        290        300 
IGAHYWHHPG SFRNGFKGFC SVFISSAYSL SGTENIGTAA GNTSNPQRAI PSAVKKVFYR 

       310        320        330        340        350        360 
MGFFYIITIF LITLVVPYDN PDLGNVSPFI IAIKNGGIHV LPHITNAVIL VSVLSVGNAA 

       370        380        390        400        410        420 
VFAASRNAMA LVKQGWAPRF LGRVDQKGRP VISYLCSLAM ACIAYVNAAP DGSVVFDWLM 

       430        440        450        460        470        480 
SVSGGGAFVI WGLSFIDHIR LRYAMKAQKI PDTVLPYKFP GSVYLSYYGV LINFLALCAL 

       490        500        510        520        530        540 
VYISIFPVTH EKPSAYGFFV SFLGPSVFIA YLLISPIFVK PTFQSLKDVD LTTGRYDLVN 

       550        560        570        580        590 
SQMYVAESST SELSEKDLTK PNLQSNDNKN SEDLESNTPP QKKSALQKVA DFLC

« Hide

References

« Hide 'large scale' references
[1]Okazaki K., Okayama H.
Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 972 / ATCC 24843.
[3]"Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library."
Ding D.-Q., Tomita Y., Yamamoto A., Chikashige Y., Haraguchi T., Hiraoka Y.
Genes Cells 5:169-190(2000) [PubMed: 10759889] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] OF 473-557.
Strain: ATCC 38364 / 968.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		D87954 Genomic DNA. Translation: BAA13506.1.
CU329671 Genomic DNA. Translation: CAB86887.1.
AB028013 Genomic DNA. Translation: BAA87317.1.
PIRT43246.
RefSeqNP_596769.2. NM_001023790.2.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiSPBC1652.02.1; SPBC1652.02.1:pep; SPBC1652.02.
GeneID2540163.
GenomeReviewsGene locus aap1 in contig CU329671_GR.
KEGGspo:SPBC1652.02.

Organism-specific databases

GeneDB_SpombeSPBC1652.02.

Phylogenomic databases

eggNOGfuNOG05282.
GeneTreeEFGT00050000001131.
HOGENOMHBG492579.
OMAAMACIAY.
OrthoDBEOG4WHCV6.

Enzyme and pathway databases

BioCycSPOM-XXX-01:SPOM-XXX-01-004823-MONOMER.

Gene expression databases

ArrayExpressQ92367.

Family and domain databases

InterProIPR004841. AA-permease_dom.
IPR002293. AA/rel_permease1.
IPR004840. Amoino_acid_permease_CS.
[Graphical view]
PANTHERPTHR11785. AA/rel_permease1. 1 hit.
PfamPF00324. AA_permease. 1 hit.
[Graphical view]
PIRSFPIRSF006060. AA_transporter. 1 hit.
PROSITEPS00218. AMINO_ACID_PERMEASE_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAAP1_SCHPO
AccessionPrimary (citable) accession number: Q92367
Secondary accession number(s): Q9P7A9, Q9UTT7
Entry history
Integrated into UniProtKB/Swiss-Prot: August 14, 2001
Last sequence update: February 1, 1997
Last modified: December 14, 2011
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents