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Protein

Synaptobrevin homolog 1

Gene

syb1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 5 out of 5-Protein inferred from homologyi

Functioni

Involved in membrane trafficking during cytokinesis and cell elongation.1 Publication

GO - Molecular functioni

GO - Biological processi

  • endocytosis Source: PomBase
  • exocytosis Source: GO_Central
  • intracellular protein transport Source: PomBase
  • vesicle fusion Source: GO_Central
  • vesicle-mediated transport Source: PomBase
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Synaptobrevin homolog 1
Gene namesi
Name:syb1
ORF Names:SPAC6G9.11
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC6G9.11.
PomBaseiSPAC6G9.11. syb1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 9797CytoplasmicSequence analysisAdd
BLAST
Transmembranei98 – 11821Helical; Anchor for type IV membrane proteinSequence analysisAdd
BLAST
Topological domaini119 – 1213VesicularSequence analysis

GO - Cellular componenti

  • cell cortex of cell tip Source: PomBase
  • cell division site Source: PomBase
  • cell tip Source: PomBase
  • cytoplasm Source: PomBase
  • cytoplasmic vesicle membrane Source: PomBase
  • endoplasmic reticulum Source: PomBase
  • Golgi apparatus Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
  • SNARE complex Source: GO_Central
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 121121Synaptobrevin homolog 1PRO_0000206746Add
BLAST

Proteomic databases

MaxQBiQ92356.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

BioGridi278225. 5 interactions.
MINTiMINT-4701259.

Structurei

3D structure databases

ProteinModelPortaliQ92356.
SMRiQ92356. Positions 31-89.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini31 – 9161v-SNARE coiled-coil homologyPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the synaptobrevin family.Curated
Contains 1 v-SNARE coiled-coil homology domain.PROSITE-ProRule annotation

Keywords - Domaini

Coiled coil, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000042711.
InParanoidiQ92356.
KOiK08513.
OMAiRLTSIQD.
OrthoDBiEOG7W9S5V.
PhylomeDBiQ92356.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92356-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEPYDPYIP AEPSAAVRSG NAAASSTPNM KTAAIQQQID DTVGIMRENI
60 70 80 90 100
SKVSERGERL DSLQDKTDNL AVSAQGFRRG ANRVRKKMWW KDMRMRLCII
110 120
IGIIILLVVI IVPIATKFHG K
Length:121
Mass (Da):13,469
Last modified:February 1, 1997 - v1
Checksum:iD10029CA0341D4DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB03613.1.
PIRiT39073.
RefSeqiNP_594120.1. NM_001019544.2.

Genome annotation databases

EnsemblFungiiSPAC6G9.11.1; SPAC6G9.11.1:pep; SPAC6G9.11.
GeneIDi2541731.
KEGGispo:SPAC6G9.11.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU329670 Genomic DNA. Translation: CAB03613.1.
PIRiT39073.
RefSeqiNP_594120.1. NM_001019544.2.

3D structure databases

ProteinModelPortaliQ92356.
SMRiQ92356. Positions 31-89.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi278225. 5 interactions.
MINTiMINT-4701259.

Proteomic databases

MaxQBiQ92356.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC6G9.11.1; SPAC6G9.11.1:pep; SPAC6G9.11.
GeneIDi2541731.
KEGGispo:SPAC6G9.11.

Organism-specific databases

EuPathDBiFungiDB:SPAC6G9.11.
PomBaseiSPAC6G9.11. syb1.

Phylogenomic databases

HOGENOMiHOG000042711.
InParanoidiQ92356.
KOiK08513.
OMAiRLTSIQD.
OrthoDBiEOG7W9S5V.
PhylomeDBiQ92356.

Miscellaneous databases

PROiQ92356.

Family and domain databases

Gene3Di1.10.3840.10. 1 hit.
InterProiIPR001388. Synaptobrevin.
IPR016444. Synaptobrevin/VAMP.
[Graphical view]
PfamiPF00957. Synaptobrevin. 1 hit.
[Graphical view]
PIRSFiPIRSF005409. Synaptobrevin_euk. 1 hit.
PRINTSiPR00219. SYNAPTOBREVN.
PROSITEiPS00417. SYNAPTOBREVIN. 1 hit.
PS50892. V_SNARE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.
  2. "Fission yeast synaptobrevin is involved in cytokinesis and cell elongation."
    Edamatsu M., Toyoshima Y.Y.
    Biochem. Biophys. Res. Commun. 301:641-645(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION, SUBCELLULAR LOCATION.

Entry informationi

Entry nameiSYB1_SCHPO
AccessioniPrimary (citable) accession number: Q92356
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: July 6, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.