Reviewed, UniProtKB/Swiss-Prot Q92338 (ABCI_SCHPO)

Names and origin

Protein names

Recommended name:
    Protein ABC1 homolog, mitochondrial

Gene names

Name:	abc1
ORF Names:	SPBC2D10.18

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	610 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Subcellular location	Mitochondrion Probable.
Sequence similarities	Belongs to the protein kinase superfamily. ADCK protein kinase family.

Ontologies

Keywords
Cellular component	Mitochondrion
Domain	Transit peptide
Molecular function	Chaperone
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	aerobic electron transport chain Traceable author statement. Source: GeneDB_SPombe cellular sulfide ion homeostasis Inferred from mutant phenotype. Source: GeneDB_SPombe sulfide oxidation Inferred from mutant phenotype. Source: GeneDB_SPombe ubiquinone biosynthetic process Ref.1 Inferred from genetic interaction. Source: GeneDB_SPombe
Cellular component	mitochondrion Inferred from direct assay. Source: GeneDB_SPombe
Molecular function	antioxidant activity Inferred from mutant phenotype. Source: GeneDB_SPombe
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – ?		Mitochondrion Potential
	Chain	? – 610		Protein ABC1 homolog, mitochondrial		PRO_0000000261

Sequences

	Sequence		Length	Mass (Da)
	Q92338-1 [UniParc]. Last modified February 1, 1997. Version 1. Checksum: ACFED14EEEA8353D	FASTA	610	68,567
	10 20 30 40 50 60 MANSGLWELI TIGSAVRNVA KSYLKAEASS ITAKQLYDAS KITSSKRSTS DLHVQLLEKY 70 80 90 100 110 120 RNGKVKHASQ IKELGLSSKD TKRTLLGNSL DVQKDASGVK HLQEQSSKEI KNPISQPILP 130 140 150 160 170 180 NKKDEISPAK PSAIDSSIKD VTKSHPATNA NFTADFESSI EESYSTENKS PVILSSSKVP 190 200 210 220 230 240 SSQWSRLWHY GGLATSLSVG AIGEKMKRMW GISKDDGALL LNERNVEILV NKLTQMRGAA 250 260 270 280 290 300 LKMGQMLSFQ DSKLIDPRVS QILERVRDGA HSMPEKQLEQ VMVKNLGKNW MTHYSEFDRK 310 320 330 340 350 360 PMAAASIGQV HRARLASNHM EVVVKVQYPG VMSSIDSDLN NLAYLLKASR ILPKGLFLEN 370 380 390 400 410 420 SLAAARKELK WECDYEREAA FAERFGSLLK NDSDFKVPMV FREASGPSVI TLEYLHGIAL 430 440 450 460 470 480 GKQKYSQATR NHIGYLLTKQ CLREISEYHF MQTDPNWSNF LYNGKTKKIE LLDFGASIEY 490 500 510 520 530 540 DEKFIKKYCR LLLAAAHRNR EKCKKLSVEL GYLNNHESAQ MIDAHINSIF TLAEPFAFDA 550 560 570 580 590 600 PDVYDFGDQT ITARVKQQIP VMLDLRLQPP PEETYSLHRR LSGHFLLCAK LGAKVRCKEL 610 FSGMLKHYAD

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Cloning by functional complementation, and inactivation, of the Schizosaccharomyces pombe homologue of the Saccharomyces cerevisiae gene ABC1." Bonnefoy N., Kermorgant M., Brivet-Chevillotte P., Dujardin G. Mol. Gen. Genet. 251:204-210(1996) [PubMed: 8668131] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2]	"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.

Cross-references

Sequence databases
EMBLGenBankDDBJ	X91616 mRNA. Translation: CAA62818.1. CU329671 Genomic DNA. Translation: CAA21176.1.
PIR	S71110. S71111.
RefSeq	NP_596237.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q92338.
Genome annotation databases
GeneID	2540411.
GenomeReviews	Gene locus abc1 in contig CU329671_GR.
KEGG	spo:SPBC2D10.18.
NMPDR	fig|4896.1.peg.2103.
Organism-specific databases
GeneDB_Spombe	SPBC2D10.18.
Phylogenomic databases
OMA	PDWQVER
OrthoDB	EOG94QVHD
Gene expression databases
ArrayExpress	Q92338.
Family and domain databases
InterPro	IPR004147. ABC_1. IPR011009. Kinase-like_dom. [Graphical view]
Pfam	PF03109. ABC1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABCI_SCHPO

Accession

Primary (citable) accession number: Q92338

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	February 1, 1997
Last modified:	November 24, 2009
This is version 60 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)