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Reviewed, UniProtKB/Swiss-Prot Q92337 (ABC1_SCHPO)

Last modified December 15, 2009. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    ATP-binding cassette transporter abc1
Gene names
Name: abc1
ORF Names: SPAC9E9.12c
OrganismSchizosaccharomyces pombe (Fission yeast) [Complete proteome]
Taxonomic identifier4896 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

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Protein attributes

Sequence length1427 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Subcellular location

Membrane; Multi-pass membrane protein Potential.

Sequence similarities

Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. [View classification]

Contains 2 ABC transmembrane type-1 domains.

Contains 2 ABC transporter domains.

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Ontologies

Keywords
   Biological processTransport
   Cellular componentMembrane
   DomainRepeat
Transmembrane
   LigandATP-binding
Nucleotide-binding
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtransmembrane transport

Inferred from electronic annotation. Source: InterPro

   Cellular componentendoplasmic reticulum membrane

Inferred from direct assay. Source: GeneDB_SPombe

integral to membrane

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionATP binding

Inferred by curator. Source: GeneDB_SPombe

ATPase activity, coupled to transmembrane movement of substances

Inferred from mutant phenotype. Source: GeneDB_SPombe

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14271427ATP-binding cassette transporter abc1
PRO_0000093303

Regions

Transmembrane26 – 4621 Potential
Transmembrane63 – 8321 Potential
Transmembrane87 – 10721 Potential
Transmembrane115 – 13521 Potential
Transmembrane155 – 17521 Potential
Transmembrane197 – 21721 Potential
Transmembrane262 – 28221 Potential
Transmembrane298 – 31821 Potential
Transmembrane345 – 36723 Potential
Transmembrane397 – 41721 Potential
Transmembrane489 – 50921 Potential
Transmembrane513 – 53321 Potential
Transmembrane609 – 62921 Potential
Transmembrane760 – 78021 Potential
Transmembrane866 – 88621 Potential
Transmembrane896 – 91621 Potential
Transmembrane973 – 99321 Potential
Transmembrane995 – 101521 Potential
Transmembrane1086 – 110621 Potential
Transmembrane1114 – 113421 Potential
Transmembrane1223 – 124321 Potential
Domain262 – 549288ABC transmembrane type-1 1
Domain579 – 807229ABC transporter 1
Domain862 – 1142281ABC transmembrane type-1 2
Domain1180 – 1422243ABC transporter 2
Nucleotide binding614 – 6218ATP 1 Potential
Nucleotide binding1214 – 12218ATP 2 Potential

Amino acid modifications

Glycosylation491N-linked (GlcNAc...) Potential
Glycosylation4371N-linked (GlcNAc...) Potential
Glycosylation5671N-linked (GlcNAc...) Potential
Glycosylation5811N-linked (GlcNAc...) Potential
Glycosylation6011N-linked (GlcNAc...) Potential
Glycosylation6581N-linked (GlcNAc...) Potential
Glycosylation7031N-linked (GlcNAc...) Potential
Glycosylation7821N-linked (GlcNAc...) Potential
Glycosylation8421N-linked (GlcNAc...) Potential
Glycosylation9941N-linked (GlcNAc...) Potential
Glycosylation11611N-linked (GlcNAc...) Potential
Glycosylation11841N-linked (GlcNAc...) Potential
Glycosylation13241N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
Q92337-1 [UniParc].

Last modified February 1, 1997. Version 1.
Checksum: 94E5FD69AB0E96C3

FASTA1,427160,612
        10         20         30         40         50         60 
MKMFQSFFSN YIDINFFRNA TLDQCLLLFY LSLFSLTNLF LIQKLFHANH TQHPLKKYFG 

        70         80         90        100        110        120 
ETCLLEYIQI ILSIVSAALS FYLDTNAVWW AIRTITHLEI VGLNILSSLK YGSTLFSWIS 

       130        140        150        160        170        180 
VANAFGLLLL RLISIYDFLT YSSWSFSVKG GSFLLLLPLA YNITLFLLVI IPLFFPRAWS 

       190        200        210        220        230        240 
PTVKFSKVAR PSPEQTCSIF SLIFTYGWLN GIIWKSWKKP ITLTDVPALP DTECTQIWYS 

       250        260        270        280        290        300 
RFAKNDRKSL MHTILLSLKS TILLMVFLSV LVSSTLFVTP LAIKKLLQYL QNPKSDEGNS 

       310        320        330        340        350        360 
PFLWVFVLLI GPYLASVVKE LYVHVSRRFM LRIKAAITQM IYKKVLTSKT LFVAVDGSKI 

       370        380        390        400        410        420 
NLDYVYNLLA KDVDNIGEMR EFIGIIARAP LEMGVSMYFL YQLLGWSAYV GLLLAILSSS 

       430        440        450        460        470        480 
FPLLVASKIS RLTSIANTSS DERIRLTTEL LKSIKITKLF GWERPMLSRI QEKRSFEVNN 

       490        500        510        520        530        540 
MYSLTLFDII FKSGMKIAPF ISMFITFAIY TKIMGHQLTP ATAFTSISMF GLLRYQFIWL 

       550        560        570        580        590        600 
ASVSRQFIQF KVSLKRVDNF VYGNMVNDSS IESSDSFVFE NTSLSWSPTP STALFQLKNL 

       610        620        630        640        650        660 
NFTIPRNQFT LVVGSTGSGK STLAMALLGE LHVISGKMTT PSISQRIAYV PQAAWLRNGT 

       670        680        690        700        710        720 
IRSNILFGEP YDEERYFQII KACCLDSDLN SMNDGDLTYI HSNGSSLSGG QKQRVSLARA 

       730        740        750        760        770        780 
LYSNAEVYIF DDIFSALDVS TSRKIYESCF LSTLLQHKTI ILFTHNVSLC LPIAENVIVL 

       790        800        810        820        830        840 
KNSTAQLVSP DSIQELVPST FFSSNTKKDN IEEENLEPHS FSFDSTLASS SDNDEQRDFA 

       850        860        870        880        890        900 
SNSSIVLLGL HYLKYFGSNK YILGSILLVM MSQVSLASIH FWIALWSGNS LFSLKLPSSF 

       910        920        930        940        950        960 
SFLWGYAILL FIYFLMDLSR AITFAKGGRT ASENIHDILS ERVLYSPLHW FEKTAAGRIL 

       970        980        990       1000       1010       1020 
NRFSKDMYAT DNLLWASLEG MLLCVMAILI TMLNVTLVMP IFMVPAAFVS LLVYLHGYAY 

      1030       1040       1050       1060       1070       1080 
SKAQKQLTSL QSSRTSPVFT MLGETLGGIT VIRAFKKEKI FEHENMAFID DMIQPLYISF 

      1090       1100       1110       1120       1130       1140 
AINRWLAIRT DGISGLVGFS TGLIALLRQN IPPGLVGFSL NSAIGFNISV LVFVRANNEI 

      1150       1160       1170       1180       1190       1200 
LTYINNFRRL YEYMLLPSEK NESSCLTKPM NKEWPTLGHV SIKNLTVSYS IGQAAVLEDI 

      1210       1220       1230       1240       1250       1260 
NLEILPKEKI AIVGRTGSGK STMGLTLLRF TMIMSGAVEV DGIDINSLDL EVLRQRISLI 

      1270       1280       1290       1300       1310       1320 
PQDPVLISGT VRSNLDPFEE YGDGELNEIL KTASCESLVQ ASNKNSLDAF AIHLDTPVDS 

      1330       1340       1350       1360       1370       1380 
GGVNFSSGQR QILALARALV RKSRIVILDE STASVDDTTD RRIQQMLRAA FKHATVLCIA 

      1390       1400       1410       1420 
HRIKTIVDYD KVLVLDSGKT VEFGSPKSLY TQRRAFWKMC KESHISL

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References

« Hide 'large scale' references
[1]"Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe."
Christensen P.U., Davis K., Nielsen O., Davey J.
FEMS Microbiol. Lett. 147:97-102(1997) [PubMed: 9037770] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"The genome sequence of Schizosaccharomyces pombe."
Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. expand/collapse author list , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
Nature 415:871-880(2002) [PubMed: 11859360] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 38366 / 972.

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Cross-references

Sequence databases

Y09354 Genomic DNA. Translation: CAA70526.1.
CU329670 Genomic DNA. Translation: CAB16410.1.
PIRT39219.
RefSeqNP_594585.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2542640.
GenomeReviewsGene locus abc1 in contig CU329670_GR.
KEGGspo:SPAC9E9.12c.
NMPDRfig|4896.1.peg.4555.

Organism-specific databases

GeneDB_SpombeSPAC9E9.12c.

Phylogenomic databases

HOGENOMHBG206983.
OMAIRQSAEM.
OrthoDBEOG9MKPZR.

Gene expression databases

ArrayExpressQ92337.

Family and domain databases

InterProIPR011527. ABC_TM_1.
IPR001140. ABC_TM_transpt.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR017940. ABC_transporter_type1.
IPR003593. ATPase_AAA+_core.
[Graphical view]
PfamPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTSM00382. AAA. 2 hits.
[Graphical view]
PROSITEPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameABC1_SCHPO
AccessionPrimary (citable) accession number: Q92337
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: December 15, 2009
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

Schizosaccharomyces pombe

Schizosaccharomyces pombe: entries and gene names

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents