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Protein

ATP-binding cassette transporter abc1

Gene

abc1

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi614 – 6218ATP 1PROSITE-ProRule annotation
Nucleotide bindingi1214 – 12218ATP 2PROSITE-ProRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Biological processi

Transport

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
ATP-binding cassette transporter abc1
Gene namesi
Name:abc1
ORF Names:SPAC9E9.12c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome I

Organism-specific databases

EuPathDBiFungiDB:SPAC9E9.12c.
PomBaseiSPAC9E9.12c.

Subcellular locationi

  • Membrane PROSITE-ProRule annotation; Multi-pass membrane protein PROSITE-ProRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei26 – 4621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei63 – 8321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei87 – 10721HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei115 – 13521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei155 – 17521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei197 – 21721HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei262 – 28221HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei298 – 31821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei345 – 36723HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei397 – 41721HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei489 – 50921HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei513 – 53321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei609 – 62921HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei760 – 78021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei866 – 88621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei896 – 91621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei973 – 99321HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei995 – 101521HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei1086 – 110621HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei1114 – 113421HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei1223 – 124321HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

  • endoplasmic reticulum Source: PomBase
  • integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 14271427ATP-binding cassette transporter abc1PRO_0000093303Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi49 – 491N-linked (GlcNAc...)Sequence analysis
Glycosylationi437 – 4371N-linked (GlcNAc...)Sequence analysis
Glycosylationi567 – 5671N-linked (GlcNAc...)Sequence analysis
Glycosylationi581 – 5811N-linked (GlcNAc...)Sequence analysis
Glycosylationi601 – 6011N-linked (GlcNAc...)Sequence analysis
Glycosylationi658 – 6581N-linked (GlcNAc...)Sequence analysis
Glycosylationi703 – 7031N-linked (GlcNAc...)Sequence analysis
Glycosylationi782 – 7821N-linked (GlcNAc...)Sequence analysis
Glycosylationi842 – 8421N-linked (GlcNAc...)Sequence analysis
Glycosylationi994 – 9941N-linked (GlcNAc...)Sequence analysis
Glycosylationi1161 – 11611N-linked (GlcNAc...)Sequence analysis
Glycosylationi1184 – 11841N-linked (GlcNAc...)Sequence analysis
Glycosylationi1324 – 13241N-linked (GlcNAc...)Sequence analysis

Keywords - PTMi

Glycoprotein

Proteomic databases

MaxQBiQ92337.

Interactioni

Protein-protein interaction databases

BioGridi279094. 10 interactions.
MINTiMINT-4701093.

Structurei

3D structure databases

ProteinModelPortaliQ92337.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini262 – 549288ABC transmembrane type-1 1PROSITE-ProRule annotationAdd
BLAST
Domaini579 – 807229ABC transporter 1PROSITE-ProRule annotationAdd
BLAST
Domaini862 – 1142281ABC transmembrane type-1 2PROSITE-ProRule annotationAdd
BLAST
Domaini1180 – 1422243ABC transporter 2PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 2 ABC transmembrane type-1 domains.PROSITE-ProRule annotation
Contains 2 ABC transporter domains.PROSITE-ProRule annotation

Keywords - Domaini

Repeat, Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000033753.
InParanoidiQ92337.
OMAiCKESHIS.
OrthoDBiEOG72JWQG.
PhylomeDBiQ92337.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q92337-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKMFQSFFSN YIDINFFRNA TLDQCLLLFY LSLFSLTNLF LIQKLFHANH
60 70 80 90 100
TQHPLKKYFG ETCLLEYIQI ILSIVSAALS FYLDTNAVWW AIRTITHLEI
110 120 130 140 150
VGLNILSSLK YGSTLFSWIS VANAFGLLLL RLISIYDFLT YSSWSFSVKG
160 170 180 190 200
GSFLLLLPLA YNITLFLLVI IPLFFPRAWS PTVKFSKVAR PSPEQTCSIF
210 220 230 240 250
SLIFTYGWLN GIIWKSWKKP ITLTDVPALP DTECTQIWYS RFAKNDRKSL
260 270 280 290 300
MHTILLSLKS TILLMVFLSV LVSSTLFVTP LAIKKLLQYL QNPKSDEGNS
310 320 330 340 350
PFLWVFVLLI GPYLASVVKE LYVHVSRRFM LRIKAAITQM IYKKVLTSKT
360 370 380 390 400
LFVAVDGSKI NLDYVYNLLA KDVDNIGEMR EFIGIIARAP LEMGVSMYFL
410 420 430 440 450
YQLLGWSAYV GLLLAILSSS FPLLVASKIS RLTSIANTSS DERIRLTTEL
460 470 480 490 500
LKSIKITKLF GWERPMLSRI QEKRSFEVNN MYSLTLFDII FKSGMKIAPF
510 520 530 540 550
ISMFITFAIY TKIMGHQLTP ATAFTSISMF GLLRYQFIWL ASVSRQFIQF
560 570 580 590 600
KVSLKRVDNF VYGNMVNDSS IESSDSFVFE NTSLSWSPTP STALFQLKNL
610 620 630 640 650
NFTIPRNQFT LVVGSTGSGK STLAMALLGE LHVISGKMTT PSISQRIAYV
660 670 680 690 700
PQAAWLRNGT IRSNILFGEP YDEERYFQII KACCLDSDLN SMNDGDLTYI
710 720 730 740 750
HSNGSSLSGG QKQRVSLARA LYSNAEVYIF DDIFSALDVS TSRKIYESCF
760 770 780 790 800
LSTLLQHKTI ILFTHNVSLC LPIAENVIVL KNSTAQLVSP DSIQELVPST
810 820 830 840 850
FFSSNTKKDN IEEENLEPHS FSFDSTLASS SDNDEQRDFA SNSSIVLLGL
860 870 880 890 900
HYLKYFGSNK YILGSILLVM MSQVSLASIH FWIALWSGNS LFSLKLPSSF
910 920 930 940 950
SFLWGYAILL FIYFLMDLSR AITFAKGGRT ASENIHDILS ERVLYSPLHW
960 970 980 990 1000
FEKTAAGRIL NRFSKDMYAT DNLLWASLEG MLLCVMAILI TMLNVTLVMP
1010 1020 1030 1040 1050
IFMVPAAFVS LLVYLHGYAY SKAQKQLTSL QSSRTSPVFT MLGETLGGIT
1060 1070 1080 1090 1100
VIRAFKKEKI FEHENMAFID DMIQPLYISF AINRWLAIRT DGISGLVGFS
1110 1120 1130 1140 1150
TGLIALLRQN IPPGLVGFSL NSAIGFNISV LVFVRANNEI LTYINNFRRL
1160 1170 1180 1190 1200
YEYMLLPSEK NESSCLTKPM NKEWPTLGHV SIKNLTVSYS IGQAAVLEDI
1210 1220 1230 1240 1250
NLEILPKEKI AIVGRTGSGK STMGLTLLRF TMIMSGAVEV DGIDINSLDL
1260 1270 1280 1290 1300
EVLRQRISLI PQDPVLISGT VRSNLDPFEE YGDGELNEIL KTASCESLVQ
1310 1320 1330 1340 1350
ASNKNSLDAF AIHLDTPVDS GGVNFSSGQR QILALARALV RKSRIVILDE
1360 1370 1380 1390 1400
STASVDDTTD RRIQQMLRAA FKHATVLCIA HRIKTIVDYD KVLVLDSGKT
1410 1420
VEFGSPKSLY TQRRAFWKMC KESHISL
Length:1,427
Mass (Da):160,612
Last modified:February 1, 1997 - v1
Checksum:i94E5FD69AB0E96C3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09354 Genomic DNA. Translation: CAA70526.1.
CU329670 Genomic DNA. Translation: CAB16410.1.
PIRiT39219.
RefSeqiNP_594585.1. NM_001020014.2.

Genome annotation databases

EnsemblFungiiSPAC9E9.12c.1; SPAC9E9.12c.1:pep; SPAC9E9.12c.
GeneIDi2542640.
KEGGispo:SPAC9E9.12c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Y09354 Genomic DNA. Translation: CAA70526.1.
CU329670 Genomic DNA. Translation: CAB16410.1.
PIRiT39219.
RefSeqiNP_594585.1. NM_001020014.2.

3D structure databases

ProteinModelPortaliQ92337.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi279094. 10 interactions.
MINTiMINT-4701093.

Proteomic databases

MaxQBiQ92337.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPAC9E9.12c.1; SPAC9E9.12c.1:pep; SPAC9E9.12c.
GeneIDi2542640.
KEGGispo:SPAC9E9.12c.

Organism-specific databases

EuPathDBiFungiDB:SPAC9E9.12c.
PomBaseiSPAC9E9.12c.

Phylogenomic databases

HOGENOMiHOG000033753.
InParanoidiQ92337.
OMAiCKESHIS.
OrthoDBiEOG72JWQG.
PhylomeDBiQ92337.

Miscellaneous databases

PROiQ92337.

Family and domain databases

Gene3Di3.40.50.300. 2 hits.
InterProiIPR003593. AAA+_ATPase.
IPR011527. ABC1_TM_dom.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR027417. P-loop_NTPase.
[Graphical view]
PfamiPF00664. ABC_membrane. 2 hits.
PF00005. ABC_tran. 2 hits.
[Graphical view]
SMARTiSM00382. AAA. 2 hits.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 2 hits.
SSF90123. SSF90123. 2 hits.
PROSITEiPS50929. ABC_TM1F. 2 hits.
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 2 hits.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Abc1: a new ABC transporter from the fission yeast Schizosaccharomyces pombe."
    Christensen P.U., Davis K., Nielsen O., Davey J.
    FEMS Microbiol. Lett. 147:97-102(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
  2. "The genome sequence of Schizosaccharomyces pombe."
    Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.
    , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P.
    Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 972 / ATCC 24843.

Entry informationi

Entry nameiABC1_SCHPO
AccessioniPrimary (citable) accession number: Q92337
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: February 1, 1997
Last modified: June 8, 2016
This is version 121 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.