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Q922H9

- ZN330_MOUSE

UniProt

Q922H9 - ZN330_MOUSE

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Protein

Zinc finger protein 330

Gene

Znf330

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri42 – 5817C4-type 1Sequence AnalysisAdd
BLAST
Zinc fingeri67 – 10438C4-type 2Sequence AnalysisAdd
BLAST
Zinc fingeri129 – 14921C4-type 3Sequence AnalysisAdd
BLAST
Zinc fingeri175 – 18915C4-type 4Sequence AnalysisAdd
BLAST

GO - Molecular functioni

  1. zinc ion binding Source: InterPro
Complete GO annotation...

Keywords - Ligandi

Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 330
Alternative name(s):
Nucleolar autoantigen 36
Nucleolar cysteine-rich protein
Gene namesi
Name:Znf330
Synonyms:Noa36, Zfp330
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 8

Organism-specific databases

MGIiMGI:1353574. Zfp330.

Subcellular locationi

Nucleus By similarity. Nucleusnucleolus By similarity. Chromosomecentromere By similarity
Note: Predominantly expressed in nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis (By similarity).By similarity

GO - Cellular componenti

  1. chromosome, centromeric region Source: UniProtKB
  2. midbody Source: UniProtKB
  3. nucleolus Source: UniProtKB
Complete GO annotation...

Keywords - Cellular componenti

Centromere, Chromosome, Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316Zinc finger protein 330PRO_0000066591Add
BLAST

Proteomic databases

MaxQBiQ922H9.
PaxDbiQ922H9.
PRIDEiQ922H9.

PTM databases

PhosphoSiteiQ922H9.

Expressioni

Gene expression databases

BgeeiQ922H9.
CleanExiMM_ZFP330.
GenevestigatoriQ922H9.

Structurei

3D structure databases

ProteinModelPortaliQ922H9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi3 – 119Nuclear localization signalSequence Analysis

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi268 – 28316Asp/Glu-rich (acidic)Add
BLAST

Sequence similaritiesi

Belongs to the NOA36 family.Curated

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri42 – 5817C4-type 1Sequence AnalysisAdd
BLAST
Zinc fingeri67 – 10438C4-type 2Sequence AnalysisAdd
BLAST
Zinc fingeri129 – 14921C4-type 3Sequence AnalysisAdd
BLAST
Zinc fingeri175 – 18915C4-type 4Sequence AnalysisAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG80468.
GeneTreeiENSGT00390000017043.
HOGENOMiHOG000030400.
HOVERGENiHBG057282.
InParanoidiQ922H9.
OMAiVWEHGGR.
OrthoDBiEOG7QVM30.
PhylomeDBiQ922H9.
TreeFamiTF323303.

Family and domain databases

InterProiIPR010531. NOA36.
[Graphical view]
PANTHERiPTHR13214. PTHR13214. 1 hit.
PfamiPF06524. NOA36. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q922H9-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MPKKKTGARK KAENRREREK QLRASRSTVD LAKHPCNASM ECDKCQRRQK
60 70 80 90 100
NRAFCYFCNS VQKLPICAQC GKTKCMMKSS DCVIKHAGVY STGLAMVGAI
110 120 130 140 150
CDFCEAWVCH GRKCLSTHAC ACPLTDAECV ECERGVWDHG GRIFSCSFCH
160 170 180 190 200
NFLCEDDQFE HQASCQVLEA ETFKCVSCNR LGQHSCLRCK ACFCDEHTRS
210 220 230 240 250
KVFKQEKGKQ PPCPKCGHET QETKDLSMST RSLKFGRQTG GEEDGASGYD
260 270 280 290 300
AYWKNLSSDK YGDTGYHDDD EEEDEAEDEE EEDGKDSDAE SSDLFNNLNL
310
GRTYASGYAH YEEQES
Length:316
Mass (Da):35,608
Last modified:December 1, 2001 - v1
Checksum:iF247E54E19876D60
GO
Isoform 2 (identifier: Q922H9-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     302-316: RTYASGYAHYEEQES → KSSPVSRDAM

Note: No experimental confirmation available.

Show »
Length:311
Mass (Da):34,894
Checksum:i9E656A9929FD3933
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei302 – 31615RTYAS…EEQES → KSSPVSRDAM in isoform 2. 1 PublicationVSP_011428Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK050534 mRNA. Translation: BAC34313.1.
AK086617 mRNA. Translation: BAC39702.1.
BC008086 mRNA. Translation: AAH08086.1.
BC030675 mRNA. Translation: AAH30675.1.
BC083081 mRNA. Translation: AAH83081.1.
CCDSiCCDS22447.1. [Q922H9-1]
RefSeqiNP_663575.1. NM_145600.1. [Q922H9-1]
UniGeneiMm.269248.

Genome annotation databases

EnsembliENSMUST00000034147; ENSMUSP00000034147; ENSMUSG00000031711. [Q922H9-1]
GeneIDi30932.
KEGGimmu:30932.
UCSCiuc009mjo.1. mouse. [Q922H9-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK050534 mRNA. Translation: BAC34313.1 .
AK086617 mRNA. Translation: BAC39702.1 .
BC008086 mRNA. Translation: AAH08086.1 .
BC030675 mRNA. Translation: AAH30675.1 .
BC083081 mRNA. Translation: AAH83081.1 .
CCDSi CCDS22447.1. [Q922H9-1 ]
RefSeqi NP_663575.1. NM_145600.1. [Q922H9-1 ]
UniGenei Mm.269248.

3D structure databases

ProteinModelPortali Q922H9.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q922H9.

Proteomic databases

MaxQBi Q922H9.
PaxDbi Q922H9.
PRIDEi Q922H9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000034147 ; ENSMUSP00000034147 ; ENSMUSG00000031711 . [Q922H9-1 ]
GeneIDi 30932.
KEGGi mmu:30932.
UCSCi uc009mjo.1. mouse. [Q922H9-1 ]

Organism-specific databases

CTDi 30932.
MGIi MGI:1353574. Zfp330.

Phylogenomic databases

eggNOGi NOG80468.
GeneTreei ENSGT00390000017043.
HOGENOMi HOG000030400.
HOVERGENi HBG057282.
InParanoidi Q922H9.
OMAi VWEHGGR.
OrthoDBi EOG7QVM30.
PhylomeDBi Q922H9.
TreeFami TF323303.

Miscellaneous databases

NextBioi 307346.
PROi Q922H9.
SOURCEi Search...

Gene expression databases

Bgeei Q922H9.
CleanExi MM_ZFP330.
Genevestigatori Q922H9.

Family and domain databases

InterProi IPR010531. NOA36.
[Graphical view ]
PANTHERi PTHR13214. PTHR13214. 1 hit.
Pfami PF06524. NOA36. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    Strain: C57BL/6J.
    Tissue: Head and Pancreas.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: FVB/N.
    Tissue: Limb and Mammary gland.

Entry informationi

Entry nameiZN330_MOUSE
AccessioniPrimary (citable) accession number: Q922H9
Secondary accession number(s): Q8C389, Q8K2M4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3