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Q922H9

- ZN330_MOUSE

UniProt

Q922H9 - ZN330_MOUSE

Protein

Zinc finger protein 330

Gene

Znf330

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 90 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri42 – 5817C4-type 1Sequence AnalysisAdd
    BLAST
    Zinc fingeri67 – 10438C4-type 2Sequence AnalysisAdd
    BLAST
    Zinc fingeri129 – 14921C4-type 3Sequence AnalysisAdd
    BLAST
    Zinc fingeri175 – 18915C4-type 4Sequence AnalysisAdd
    BLAST

    GO - Molecular functioni

    1. zinc ion binding Source: InterPro

    Keywords - Ligandi

    Metal-binding, Zinc

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Zinc finger protein 330
    Alternative name(s):
    Nucleolar autoantigen 36
    Nucleolar cysteine-rich protein
    Gene namesi
    Name:Znf330
    Synonyms:Noa36, Zfp330
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 8

    Organism-specific databases

    MGIiMGI:1353574. Zfp330.

    Subcellular locationi

    Nucleus By similarity. Nucleusnucleolus By similarity. Chromosomecentromere By similarity
    Note: Predominantly expressed in nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis By similarity.By similarity

    GO - Cellular componenti

    1. chromosome, centromeric region Source: UniProtKB
    2. midbody Source: UniProtKB
    3. nucleolus Source: UniProtKB

    Keywords - Cellular componenti

    Centromere, Chromosome, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 316316Zinc finger protein 330PRO_0000066591Add
    BLAST

    Proteomic databases

    PaxDbiQ922H9.
    PRIDEiQ922H9.

    PTM databases

    PhosphoSiteiQ922H9.

    Expressioni

    Gene expression databases

    BgeeiQ922H9.
    CleanExiMM_ZFP330.
    GenevestigatoriQ922H9.

    Structurei

    3D structure databases

    ProteinModelPortaliQ922H9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi3 – 119Nuclear localization signalSequence Analysis

    Compositional bias

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Compositional biasi268 – 28316Asp/Glu-rich (acidic)Add
    BLAST

    Sequence similaritiesi

    Belongs to the NOA36 family.Curated

    Zinc finger

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Zinc fingeri42 – 5817C4-type 1Sequence AnalysisAdd
    BLAST
    Zinc fingeri67 – 10438C4-type 2Sequence AnalysisAdd
    BLAST
    Zinc fingeri129 – 14921C4-type 3Sequence AnalysisAdd
    BLAST
    Zinc fingeri175 – 18915C4-type 4Sequence AnalysisAdd
    BLAST

    Keywords - Domaini

    Repeat, Zinc-finger

    Phylogenomic databases

    eggNOGiNOG80468.
    GeneTreeiENSGT00390000017043.
    HOGENOMiHOG000030400.
    HOVERGENiHBG057282.
    InParanoidiQ922H9.
    OMAiVWEHGGR.
    OrthoDBiEOG7QVM30.
    PhylomeDBiQ922H9.
    TreeFamiTF323303.

    Family and domain databases

    InterProiIPR010531. NOA36.
    [Graphical view]
    PANTHERiPTHR13214. PTHR13214. 1 hit.
    PfamiPF06524. NOA36. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q922H9-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MPKKKTGARK KAENRREREK QLRASRSTVD LAKHPCNASM ECDKCQRRQK    50
    NRAFCYFCNS VQKLPICAQC GKTKCMMKSS DCVIKHAGVY STGLAMVGAI 100
    CDFCEAWVCH GRKCLSTHAC ACPLTDAECV ECERGVWDHG GRIFSCSFCH 150
    NFLCEDDQFE HQASCQVLEA ETFKCVSCNR LGQHSCLRCK ACFCDEHTRS 200
    KVFKQEKGKQ PPCPKCGHET QETKDLSMST RSLKFGRQTG GEEDGASGYD 250
    AYWKNLSSDK YGDTGYHDDD EEEDEAEDEE EEDGKDSDAE SSDLFNNLNL 300
    GRTYASGYAH YEEQES 316
    Length:316
    Mass (Da):35,608
    Last modified:December 1, 2001 - v1
    Checksum:iF247E54E19876D60
    GO
    Isoform 2 (identifier: Q922H9-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         302-316: RTYASGYAHYEEQES → KSSPVSRDAM

    Note: No experimental confirmation available.

    Show »
    Length:311
    Mass (Da):34,894
    Checksum:i9E656A9929FD3933
    GO

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei302 – 31615RTYAS…EEQES → KSSPVSRDAM in isoform 2. 1 PublicationVSP_011428Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK050534 mRNA. Translation: BAC34313.1.
    AK086617 mRNA. Translation: BAC39702.1.
    BC008086 mRNA. Translation: AAH08086.1.
    BC030675 mRNA. Translation: AAH30675.1.
    BC083081 mRNA. Translation: AAH83081.1.
    CCDSiCCDS22447.1. [Q922H9-1]
    RefSeqiNP_663575.1. NM_145600.1. [Q922H9-1]
    UniGeneiMm.269248.

    Genome annotation databases

    EnsembliENSMUST00000034147; ENSMUSP00000034147; ENSMUSG00000031711. [Q922H9-1]
    GeneIDi30932.
    KEGGimmu:30932.
    UCSCiuc009mjo.1. mouse. [Q922H9-1]

    Keywords - Coding sequence diversityi

    Alternative splicing

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK050534 mRNA. Translation: BAC34313.1 .
    AK086617 mRNA. Translation: BAC39702.1 .
    BC008086 mRNA. Translation: AAH08086.1 .
    BC030675 mRNA. Translation: AAH30675.1 .
    BC083081 mRNA. Translation: AAH83081.1 .
    CCDSi CCDS22447.1. [Q922H9-1 ]
    RefSeqi NP_663575.1. NM_145600.1. [Q922H9-1 ]
    UniGenei Mm.269248.

    3D structure databases

    ProteinModelPortali Q922H9.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q922H9.

    Proteomic databases

    PaxDbi Q922H9.
    PRIDEi Q922H9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000034147 ; ENSMUSP00000034147 ; ENSMUSG00000031711 . [Q922H9-1 ]
    GeneIDi 30932.
    KEGGi mmu:30932.
    UCSCi uc009mjo.1. mouse. [Q922H9-1 ]

    Organism-specific databases

    CTDi 30932.
    MGIi MGI:1353574. Zfp330.

    Phylogenomic databases

    eggNOGi NOG80468.
    GeneTreei ENSGT00390000017043.
    HOGENOMi HOG000030400.
    HOVERGENi HBG057282.
    InParanoidi Q922H9.
    OMAi VWEHGGR.
    OrthoDBi EOG7QVM30.
    PhylomeDBi Q922H9.
    TreeFami TF323303.

    Miscellaneous databases

    NextBioi 307346.
    PROi Q922H9.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q922H9.
    CleanExi MM_ZFP330.
    Genevestigatori Q922H9.

    Family and domain databases

    InterProi IPR010531. NOA36.
    [Graphical view ]
    PANTHERi PTHR13214. PTHR13214. 1 hit.
    Pfami PF06524. NOA36. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
      Strain: C57BL/6J.
      Tissue: Head and Pancreas.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
      Strain: FVB/N.
      Tissue: Limb and Mammary gland.

    Entry informationi

    Entry nameiZN330_MOUSE
    AccessioniPrimary (citable) accession number: Q922H9
    Secondary accession number(s): Q8C389, Q8K2M4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: August 31, 2004
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 90 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3