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Q922H9 (ZN330_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Zinc finger protein 330
Alternative name(s):
Nucleolar autoantigen 36
Nucleolar cysteine-rich protein
Gene names
Name:Znf330
Synonyms:Noa36, Zfp330
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length316 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity. Nucleus › nucleolus By similarity. Chromosome › centromere By similarity. Note: Predominantly expressed in nucleolus. In mitosis associated with centromeres and concentrated at the midbody in cytokinesis By similarity.

Sequence similarities

Belongs to the NOA36 family.

Ontologies

Keywords
   Cellular componentCentromere
Chromosome
Nucleus
   Coding sequence diversityAlternative splicing
   DomainZinc-finger
   LigandMetal-binding
Zinc
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentchromosome, centromeric region

Inferred from sequence or structural similarity. Source: UniProtKB

midbody

Inferred from sequence or structural similarity. Source: UniProtKB

nucleolus

Inferred from sequence or structural similarity. Source: UniProtKB

   Molecular_functionzinc ion binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q922H9-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q922H9-2)

The sequence of this isoform differs from the canonical sequence as follows:
     302-316: RTYASGYAHYEEQES → KSSPVSRDAM
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 316316Zinc finger protein 330
PRO_0000066591

Regions

Zinc finger42 – 5817C4-type 1 Potential
Zinc finger67 – 10438C4-type 2 Potential
Zinc finger129 – 14921C4-type 3 Potential
Zinc finger175 – 18915C4-type 4 Potential
Motif3 – 119Nuclear localization signal Potential
Compositional bias268 – 28316Asp/Glu-rich (acidic)

Natural variations

Alternative sequence302 – 31615RTYAS…EEQES → KSSPVSRDAM in isoform 2.
VSP_011428

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: F247E54E19876D60

FASTA31635,608
        10         20         30         40         50         60 
MPKKKTGARK KAENRREREK QLRASRSTVD LAKHPCNASM ECDKCQRRQK NRAFCYFCNS 

        70         80         90        100        110        120 
VQKLPICAQC GKTKCMMKSS DCVIKHAGVY STGLAMVGAI CDFCEAWVCH GRKCLSTHAC 

       130        140        150        160        170        180 
ACPLTDAECV ECERGVWDHG GRIFSCSFCH NFLCEDDQFE HQASCQVLEA ETFKCVSCNR 

       190        200        210        220        230        240 
LGQHSCLRCK ACFCDEHTRS KVFKQEKGKQ PPCPKCGHET QETKDLSMST RSLKFGRQTG 

       250        260        270        280        290        300 
GEEDGASGYD AYWKNLSSDK YGDTGYHDDD EEEDEAEDEE EEDGKDSDAE SSDLFNNLNL 

       310 
GRTYASGYAH YEEQES

« Hide

Isoform 2 [UniParc].

Checksum: 9E656A9929FD3933
Show »

FASTA31134,894

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
Strain: C57BL/6J.
Tissue: Head and Pancreas.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
Strain: FVB/N.
Tissue: Limb and Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK050534 mRNA. Translation: BAC34313.1.
AK086617 mRNA. Translation: BAC39702.1.
BC008086 mRNA. Translation: AAH08086.1.
BC030675 mRNA. Translation: AAH30675.1.
BC083081 mRNA. Translation: AAH83081.1.
IPIIPI00123012.
IPI00457483.
RefSeqNP_663575.1. NM_145600.1.
UniGeneMm.269248.

3D structure databases

ProteinModelPortalQ922H9.
ModBaseSearch...

PTM databases

PhosphoSiteQ922H9.

Proteomic databases

PaxDbQ922H9.
PRIDEQ922H9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000034147; ENSMUSP00000034147; ENSMUSG00000031711.
GeneID30932.
KEGGmmu:30932.
UCSCuc009mjo.1. mouse.

Organism-specific databases

CTD30932.
MGIMGI:1353574. Zfp330.

Phylogenomic databases

eggNOGNOG80468.
GeneTreeENSGT00390000017043.
HOGENOMHOG000030400.
HOVERGENHBG057282.
InParanoidQ922H9.
OMAVWEHGGR.
OrthoDBEOG4S7JQQ.

Gene expression databases

BgeeQ922H9.
CleanExMM_ZFP330.
GenevestigatorQ922H9.
GermOnlineENSMUSG00000031711. Mus musculus.

Family and domain databases

InterProIPR010531. NOA36.
[Graphical view]
PANTHERPTHR13214. PTHR13214. 1 hit.
PfamPF06524. NOA36. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio307346.
SOURCESearch...

Entry information

Entry nameZN330_MOUSE
AccessionPrimary (citable) accession number: Q922H9
Secondary accession number(s): Q8C389, Q8K2M4
Entry history
Integrated into UniProtKB/Swiss-Prot: August 31, 2004
Last sequence update: December 1, 2001
Last modified: April 3, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents