ID   Q92270_RHIOL            Unreviewed;       400 AA.
AC   Q92270;
DT   01-FEB-1997, integrated into UniProtKB/TrEMBL.
DT   01-FEB-1997, sequence version 1.
DT   27-MAR-2024, entry version 99.
DE   SubName: Full=Chitinase {ECO:0000313|EMBL:BAA13489.1};
GN   Name=chi3 {ECO:0000313|EMBL:BAA13489.1};
OS   Rhizopus oligosporus (Rhizopus microsporus var. oligosporus).
OC   Eukaryota; Fungi; Fungi incertae sedis; Mucoromycota; Mucoromycotina;
OC   Mucoromycetes; Mucorales; Mucorineae; Rhizopodaceae; Rhizopus.
OX   NCBI_TaxID=4847 {ECO:0000313|EMBL:BAA13489.1};
RN   [1] {ECO:0000313|EMBL:BAA13489.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=IFO8631 {ECO:0000313|EMBL:BAA13489.1};
RX   PubMed=9782514;
RA   Takaya N., Yamazaki D., Horiuchi H., Ohta A., Takagi M.;
RT   "Intracellular chitinase gene from Rhizopus oligosporus: molecular cloning
RT   and characterization.";
RL   Microbiology 144:2647-2654(1998).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Random endo-hydrolysis of N-acetyl-beta-D-glucosaminide
CC         (1->4)-beta-linkages in chitin and chitodextrins.; EC=3.2.1.14;
CC         Evidence={ECO:0000256|ARBA:ARBA00000822};
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 18 family.
CC       {ECO:0000256|RuleBase:RU004453}.
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DR   EMBL; D87894; BAA13489.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q92270; -.
DR   CAZy; GH18; Glycoside Hydrolase Family 18.
DR   CLAE; CHI18C_RHIOL; -.
DR   GO; GO:0008061; F:chitin binding; IEA:InterPro.
DR   GO; GO:0004568; F:chitinase activity; IEA:UniProtKB-EC.
DR   GO; GO:0006032; P:chitin catabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0000272; P:polysaccharide catabolic process; IEA:UniProtKB-KW.
DR   CDD; cd06548; GH18_chitinase; 1.
DR   Gene3D; 3.10.50.10; -; 1.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   InterPro; IPR011583; Chitinase_II.
DR   InterPro; IPR029070; Chitinase_insertion_sf.
DR   InterPro; IPR001223; Glyco_hydro18_cat.
DR   InterPro; IPR001579; Glyco_hydro_18_chit_AS.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11177; CHITINASE; 1.
DR   PANTHER; PTHR11177:SF317; CHITINASE 11; 1.
DR   Pfam; PF00704; Glyco_hydro_18; 1.
DR   SMART; SM00636; Glyco_18; 1.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   SUPFAM; SSF54556; Chitinase insertion domain; 1.
DR   PROSITE; PS01095; GH18_1; 1.
DR   PROSITE; PS51910; GH18_2; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW   Chitin degradation {ECO:0000256|ARBA:ARBA00023024};
KW   Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU000489};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU000489};
KW   Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326}.
FT   DOMAIN          10..377
FT                   /note="GH18"
FT                   /evidence="ECO:0000259|PROSITE:PS51910"
SQ   SEQUENCE   400 AA;  45791 MW;  D17A91EE98958741 CRC64;
     MEPPPATNGP VIAGYFANWG IYDRKYNVVD VATQANKLTH ILYAFANVQP DGQVVLGDAY
     ADIEKHFPAN QAVNRKEDGW NDPGKNLYGN FKQFYLLKQQ HRHLKVSLSI GGYTWSTHFG
     PVARDPQKRR LFVDSSIKHL ANLGLDGLDI DWEYPKDDEE AFYYVHLLYE LRLALDRYQQ
     QCQQLIQSRL LLTVAVPCGP DHYRKLRLTE MQPYVDLFYL MAYDYAGSWD SFADHQAAVY
     GGRLNTEQAV QHYIACGIPP YKLVVGMPLY GRGFCNTAGP GHPFQGLPRG TWEEGQFNYK
     TLPKPGAVEY HDFNRLASWS YDPQAREFIT YDTPQMVAAK CNYIQQRRLG GAMFWELSAD
     CPQRSLINAA YDGLGRRLDQ VPNHLDYPMS EYDNVRNGMK
//