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Q921N8

- Q921N8_MOUSE

UniProt

Q921N8 - Q921N8_MOUSE

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Protein
Submitted name: G protein pathway suppressor 2
Gene
Gps2, mCG_22494
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. protein binding Source: MGI
  2. transcription corepressor activity Source: Ensembl

GO - Biological processi

  1. negative regulation of JNK cascade Source: Ensembl
  2. negative regulation of transcription from RNA polymerase II promoter Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
G protein pathway suppressor 2Imported
Submitted name:
MCG22494, isoform CRA_bImported
Submitted name:
Protein Gps2Imported
Gene namesi
ORF Names:mCG_22494Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 11

Organism-specific databases

MGIiMGI:1891751. Gps2.

Subcellular locationi

GO - Cellular componenti

  1. nucleus Source: MGI
  2. transcriptional repressor complex Source: Ensembl
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ921N8.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000054072.

Family & Domainsi

Phylogenomic databases

eggNOGiNOG46035.
GeneTreeiENSGT00390000004049.
HOGENOMiHOG000112796.
HOVERGENiHBG005905.
InParanoidiQ921N8.
KOiK15307.
OMAiKHIMRER.
TreeFamiTF329067.

Family and domain databases

InterProiIPR026094. GPS2.
[Graphical view]
PANTHERiPTHR22654. PTHR22654. 1 hit.

Sequencei

Sequence statusi: Complete.

Q921N8-1 [UniParc]FASTAAdd to Basket

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MPALLERPKL SNAMARALHR HIMMERERKR QEEEEVDKMM EQKMKEEQER    50
RKKKEMEERM SLEETKEQIL KLQEKLSALQ EEKHQLFLQL KKVLHEEEKR 100
RRKEQSDLTT LTSAAYQQSL TVHTGTHLLS MQGSPGGHNR PGTLMAADRA 150
KQMFGPQVLT TRHYVGSAAA FAGTPEHGQF QGSPGGAYGT AQPPPHYGPT 200
QPAYSPSQQL RAPSAFPAVQ YLSQPQPQPY AVHGHFQPTQ TGFLQPGSTL 250
SLQKQMEHAN QQTSFSDSSS LRPMHPQALH PAPGLLASPQ LPVQIQAAGK 300
SGFATTSQPG PRLPFIQHSQ NPRFYHK 327
Length:327
Mass (Da):36,738
Last modified:December 1, 2001 - v1
Checksum:i3008661CE6579F4B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596185 Genomic DNA. No translation available.
BC011317 mRNA. Translation: AAH11317.1.
BC138879 mRNA. Translation: AAI38880.1.
BC138880 mRNA. Translation: AAI38881.1.
CH466596 Genomic DNA. Translation: EDL12472.1.
CH466596 Genomic DNA. Translation: EDL12474.1.
RefSeqiNP_062700.2. NM_019726.3.
XP_006533850.1. XM_006533787.1.
XP_006537253.1. XM_006537190.1.
UniGeneiMm.477738.

Genome annotation databases

EnsembliENSMUST00000057884; ENSMUSP00000054072; ENSMUSG00000023170.
ENSMUST00000072581; ENSMUSP00000072389; ENSMUSG00000023170.
ENSMUST00000116358; ENSMUSP00000112062; ENSMUSG00000023170.
GeneIDi56310.
KEGGimmu:56310.
UCSCiuc007jsp.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AL596185 Genomic DNA. No translation available.
BC011317 mRNA. Translation: AAH11317.1 .
BC138879 mRNA. Translation: AAI38880.1 .
BC138880 mRNA. Translation: AAI38881.1 .
CH466596 Genomic DNA. Translation: EDL12472.1 .
CH466596 Genomic DNA. Translation: EDL12474.1 .
RefSeqi NP_062700.2. NM_019726.3.
XP_006533850.1. XM_006533787.1.
XP_006537253.1. XM_006537190.1.
UniGenei Mm.477738.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000054072.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000057884 ; ENSMUSP00000054072 ; ENSMUSG00000023170 .
ENSMUST00000072581 ; ENSMUSP00000072389 ; ENSMUSG00000023170 .
ENSMUST00000116358 ; ENSMUSP00000112062 ; ENSMUSG00000023170 .
GeneIDi 56310.
KEGGi mmu:56310.
UCSCi uc007jsp.1. mouse.

Organism-specific databases

CTDi 2874.
MGIi MGI:1891751. Gps2.

Phylogenomic databases

eggNOGi NOG46035.
GeneTreei ENSGT00390000004049.
HOGENOMi HOG000112796.
HOVERGENi HBG005905.
InParanoidi Q921N8.
KOi K15307.
OMAi KHIMRER.
TreeFami TF329067.

Miscellaneous databases

NextBioi 312252.
PROi Q921N8.
SOURCEi Search...

Gene expression databases

Genevestigatori Q921N8.

Family and domain databases

InterProi IPR026094. GPS2.
[Graphical view ]
PANTHERi PTHR22654. PTHR22654. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: BrainImported and Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.
  3. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  5. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ921N8_MOUSE
AccessioniPrimary (citable) accession number: Q921N8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 11, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

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