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Protein

Histone H3

Gene

hist1h3g

Organism
Xenopus laevis (African clawed frog)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H3UniRule annotation
Gene namesi
Name:hist1h3gImported
Synonyms:H3lImported
OrganismiXenopus laevis (African clawed frog)Imported
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-5784387. hist1h3g.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotation, NucleusUniRule annotationSAAS annotation

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotation

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-60191N.
IntActiQ92133. 1 interactor.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
2L11NMR-B2-16[»]
2L12NMR-B2-16[»]
2L1BNMR-B20-34[»]
3GL6X-ray1.90B2-10[»]
3H91X-ray1.50C/D20-34[»]
3ME9X-ray1.37C/D2-12[»]
3MEAX-ray1.26B2-12[»]
3METX-ray2.00C/D2-12[»]
3MEUX-ray1.28C/D2-14[»]
3MEVX-ray1.83C/D2-9[»]
3O7AX-ray1.67B2-12[»]
4HSUX-ray1.99C2-31[»]
4QEOX-ray2.00P2-16[»]
ProteinModelPortaliQ92133.
SMRiQ92133.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ92133.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 132HistoneInterPro annotationAdd BLAST132

Sequence similaritiesi

Belongs to the histone H3 family.UniRule annotationSAAS annotation

Phylogenomic databases

HOVERGENiHBG001172.
KOiK11253.

Family and domain databases

InterProiView protein in InterPro
IPR009072. Histone-fold.
IPR007125. Histone_H2A/H2B/H3.
IPR000164. Histone_H3/CENP-A.
PANTHERiPTHR11426. PTHR11426. 1 hit.
PfamiView protein in Pfam
PF00125. Histone. 1 hit.
PRINTSiPR00622. HISTONEH3.
SMARTiView protein in SMART
SM00428. H3. 1 hit.
SUPFAMiSSF47113. SSF47113. 1 hit.
PROSITEiView protein in PROSITE
PS00322. HISTONE_H3_1. 1 hit.
PS00959. HISTONE_H3_2. 1 hit.

Sequencei

Sequence statusi: Complete.

Q92133-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MARTKQTARK STGGKAPRKQ LATKAARKSA PATGGVKKPH RYRPGTVALR
60 70 80 90 100
EIRRYQKSTE LLIRKLPFQR LVREIAQDFK TDLRFQSSAV MALQEASEAY
110 120 130
LVGLFEDTNL CGIHAKRVTI MPKDIQLARR IRGERA
Length:136
Mass (Da):15,374
Last modified:November 1, 1996 - v1
Checksum:i69B8368EA50A0EEC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X72950 Genomic DNA. Translation: CAA51455.1.
PIRiS32638.
RefSeqiNP_001091119.1. NM_001097650.1.
UniGeneiXl.79297.
Xl.79618.

Genome annotation databases

GeneIDi399088.
KEGGixla:399088.

Similar proteinsi

Entry informationi

Entry nameiQ92133_XENLA
AccessioniPrimary (citable) accession number: Q92133
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: August 30, 2017
This is version 118 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources