Reviewed, UniProtKB/Swiss-Prot Q92060 (MAOX_CHICK)

Names and origin

Protein names

Recommended name:
    NADP-dependent malic enzyme
      Short name=NADP-ME
    EC=1.1.1.40

Gene names

Name:

ME1

Organism

Gallus gallus (Chicken)

Taxonomic identifier

9031 [NCBI]

Taxonomic lineage

Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Archosauria › Dinosauria › Saurischia › Theropoda › Coelurosauria › Aves › Neognathae › Galliformes › Phasianidae › Phasianinae › Gallus

Protein attributes

Sequence length	15 AA.
Sequence status	Fragment.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + NADP+ = pyruvate + CO2 + NADPH.
Subunit structure	Homotetramer By similarity.
Subcellular location	Cytoplasm.
Sequence similarities	Belongs to the malic enzymes family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	malate dehydrogenase (oxaloacetate-decarboxylating) (NADP+) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – ›15	›15	NADP-dependent malic enzyme		PRO_0000160197
Experimental info
	Non-terminal residue	15	1

Sequences

	Sequence		Length	Mass (Da)
	Q92060-1 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: CFEF180B2BA84C2B	FASTA	15	1,842
	10 MKRGYEVVRD PHLNK

References

[1]

"The chicken malic enzyme gene: structural organization and identification of triiodothyronine response elements in the 5'-flanking DNA." Hodnett D.W., Fantozzi D.A., Thurmond D.C., Klautky S.A., Macphee K.G., Estrem S.T., Xu G., Goodridge A.G. Arch. Biochem. Biophys. 334:309-324(1996) [PubMed: 8900406] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	U49693 Genomic DNA. Translation: AAA92721.1.
IPI	IPI00583828.
3D structure databases
ModBase	Search...
Phylogenomic databases
HOVERGEN	Q92060.
Enzyme and pathway databases
BRENDA	1.1.1.40. 4.
Family and domain databases
PROSITE	PS00331. MALIC_ENZYMES. Partial match. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MAOX_CHICK

Accession

Primary (citable) accession number: Q92060

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 15, 1998
Last sequence update:	November 1, 1996
Last modified:	November 24, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)