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Q91ZX8

- Q91ZX8_RAT

UniProt

Q91ZX8 - Q91ZX8_RAT

Protein
Submitted name:

Cyclin A2

Gene

Ccna2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 78 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. organ regeneration Source: RGD
    2. positive regulation of fibroblast proliferation Source: RGD
    3. regulation of cyclin-dependent protein serine/threonine kinase activity Source: InterPro
    4. regulation of G2/M transition of mitotic cell cycle Source: InterPro
    5. response to estradiol Source: RGD
    6. response to glucagon Source: RGD

    Keywords - Molecular functioni

    CyclinUniRule annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Cyclin A2Imported
    Gene namesi
    Name:Ccna2Imported
    OrganismiRattus norvegicus (Rat)Imported
    Taxonomic identifieri10116 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

    Organism-specific databases

    RGDi621059. Ccna2.

    Expressioni

    Gene expression databases

    GenevestigatoriQ91ZX8.

    Structurei

    3D structure databases

    ProteinModelPortaliQ91ZX8.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cyclin family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG106244.
    InParanoidiQ91ZX8.
    KOiK06627.
    PhylomeDBiQ91ZX8.

    Family and domain databases

    Gene3Di1.10.472.10. 1 hit.
    InterProiIPR013763. Cyclin-like.
    IPR014400. Cyclin_A/B/D/E/F.
    IPR015453. Cyclin_A_chordates.
    IPR006671. Cyclin_N.
    [Graphical view]
    PANTHERiPTHR10177:SF69. PTHR10177:SF69. 1 hit.
    PfamiPF00134. Cyclin_N. 1 hit.
    [Graphical view]
    PIRSFiPIRSF001771. Cyclin_A_B_D_E. 1 hit.
    SMARTiSM00385. CYCLIN. 1 hit.
    [Graphical view]
    SUPFAMiSSF47954. SSF47954. 1 hit.
    PROSITEiPS00292. CYCLINS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q91ZX8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPGIARQAGS ALLSQQEDQE NVNPEKVAPA QQPRAQAVLK AGKVRGPAPQ    50
    QRLKTRRVAP LKDLPINDEH VPTVPSWKAV SKQPAFTIHV DEAEETQKRP 100
    AERKETQCED ALAFSAAVSL PGARKPLVPL DYPMDGSFES PHAMDISIVL 150
    EDEKPVNVNE VPDYHEDIHT YLGEMEVKCK PKVSYMKRQP DITNSMRAIL 200
    VDWLVEVGEE YKLQNETLHL AVNYIDRFLF SMSALRGKLQ LVGTAAMLLA 250
    SKFEEIYPPE VAEFV 265
    Length:265
    Mass (Da):29,619
    Last modified:December 1, 2001 - v1
    Checksum:iFACE7AC47D6A1289
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei265 – 2651Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF367448 mRNA. Translation: AAK56923.1.
    RefSeqiNP_446154.3. NM_053702.3.
    UniGeneiRn.13094.

    Genome annotation databases

    GeneIDi114494.
    KEGGirno:114494.
    UCSCiRGD:621059. rat.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AF367448 mRNA. Translation: AAK56923.1 .
    RefSeqi NP_446154.3. NM_053702.3.
    UniGenei Rn.13094.

    3D structure databases

    ProteinModelPortali Q91ZX8.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 114494.
    KEGGi rno:114494.
    UCSCi RGD:621059. rat.

    Organism-specific databases

    CTDi 890.
    RGDi 621059. Ccna2.

    Phylogenomic databases

    HOVERGENi HBG106244.
    InParanoidi Q91ZX8.
    KOi K06627.
    PhylomeDBi Q91ZX8.

    Miscellaneous databases

    NextBioi 618537.

    Gene expression databases

    Genevestigatori Q91ZX8.

    Family and domain databases

    Gene3Di 1.10.472.10. 1 hit.
    InterProi IPR013763. Cyclin-like.
    IPR014400. Cyclin_A/B/D/E/F.
    IPR015453. Cyclin_A_chordates.
    IPR006671. Cyclin_N.
    [Graphical view ]
    PANTHERi PTHR10177:SF69. PTHR10177:SF69. 1 hit.
    Pfami PF00134. Cyclin_N. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF001771. Cyclin_A_B_D_E. 1 hit.
    SMARTi SM00385. CYCLIN. 1 hit.
    [Graphical view ]
    SUPFAMi SSF47954. SSF47954. 1 hit.
    PROSITEi PS00292. CYCLINS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Inhibition of anchorage-independent cell growth, adhesion, and cyclin D1 gene expression by a dominant negative mutant of a tyrosine phosphatase."
      Mitra S.K., Swarup G.
      Exp. Cell Res. 270:32-44(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: LungImported.

    Entry informationi

    Entry nameiQ91ZX8_RAT
    AccessioniPrimary (citable) accession number: Q91ZX8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 1, 2001
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 78 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)