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Protein
Submitted name:

Cyclin A2

Gene

Ccna2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • animal organ regeneration Source: RGD
  • cellular response to cocaine Source: RGD
  • cellular response to estradiol stimulus Source: RGD
  • cellular response to hypoxia Source: RGD
  • cellular response to insulin-like growth factor stimulus Source: RGD
  • cellular response to leptin stimulus Source: RGD
  • cellular response to luteinizing hormone stimulus Source: RGD
  • cellular response to nitric oxide Source: RGD
  • cellular response to organic cyclic compound Source: RGD
  • cellular response to platelet-derived growth factor stimulus Source: RGD
  • cochlea development Source: RGD
  • positive regulation of fibroblast proliferation Source: RGD
  • regulation of cyclin-dependent protein serine/threonine kinase activity Source: InterPro
  • regulation of G2/M transition of mitotic cell cycle Source: InterPro
  • response to estradiol Source: RGD
  • response to glucagon Source: RGD

Keywordsi

Molecular functionCyclinUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin A2Imported
Gene namesi
Name:Ccna2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621059. Ccna2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Proteomic databases

PaxDbiQ91ZX8.

Expressioni

Gene expression databases

GenevisibleiQ91ZX8. RN.

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliQ91ZX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini197 – 228Cyclin N-terminalInterPro annotationAdd BLAST32

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0654. Eukaryota.
COG5024. LUCA.
HOVERGENiHBG106244.
KOiK06627.
PhylomeDBiQ91ZX8.

Family and domain databases

CDDicd00043. CYCLIN. 1 hit.
Gene3Di1.10.472.10. 1 hit.
InterProiView protein in InterPro
IPR032447. Cyclin-A_N.
IPR013763. Cyclin-like.
IPR015453. Cyclin_A2_chordates.
IPR006671. Cyclin_N.
PANTHERiPTHR10177:SF307. PTHR10177:SF307. 1 hit.
PfamiView protein in Pfam
PF00134. Cyclin_N. 1 hit.
PF16500. Cyclin_N2. 1 hit.
SMARTiView protein in SMART
SM00385. CYCLIN. 1 hit.
SUPFAMiSSF47954. SSF47954. 1 hit.
PROSITEiView protein in PROSITE
PS00292. CYCLINS. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q91ZX8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPGIARQAGS ALLSQQEDQE NVNPEKVAPA QQPRAQAVLK AGKVRGPAPQ
60 70 80 90 100
QRLKTRRVAP LKDLPINDEH VPTVPSWKAV SKQPAFTIHV DEAEETQKRP
110 120 130 140 150
AERKETQCED ALAFSAAVSL PGARKPLVPL DYPMDGSFES PHAMDISIVL
160 170 180 190 200
EDEKPVNVNE VPDYHEDIHT YLGEMEVKCK PKVSYMKRQP DITNSMRAIL
210 220 230 240 250
VDWLVEVGEE YKLQNETLHL AVNYIDRFLF SMSALRGKLQ LVGTAAMLLA
260
SKFEEIYPPE VAEFV
Length:265
Mass (Da):29,619
Last modified:December 1, 2001 - v1
Checksum:iFACE7AC47D6A1289
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei265Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367448 mRNA. Translation: AAK56923.1.
RefSeqiNP_446154.3. NM_053702.3.
UniGeneiRn.13094.

Genome annotation databases

GeneIDi114494.
KEGGirno:114494.
UCSCiRGD:621059. rat.

Entry informationi

Entry nameiQ91ZX8_RAT
AccessioniPrimary (citable) accession number: Q91ZX8
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: September 27, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)