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Q91ZX8

- Q91ZX8_RAT

UniProt

Q91ZX8 - Q91ZX8_RAT

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Protein
Submitted name:

Cyclin A2

Gene

Ccna2

Organism
Rattus norvegicus (Rat)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. organ regeneration Source: RGD
  2. positive regulation of fibroblast proliferation Source: RGD
  3. regulation of cyclin-dependent protein serine/threonine kinase activity Source: InterPro
  4. regulation of G2/M transition of mitotic cell cycle Source: InterPro
  5. response to estradiol Source: RGD
  6. response to glucagon Source: RGD
Complete GO annotation...

Keywords - Molecular functioni

CyclinUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Cyclin A2Imported
Gene namesi
Name:Ccna2Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi621059. Ccna2.

Expressioni

Gene expression databases

GenevestigatoriQ91ZX8.

Structurei

3D structure databases

ProteinModelPortaliQ91ZX8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG106244.
KOiK06627.
PhylomeDBiQ91ZX8.

Family and domain databases

Gene3Di1.10.472.10. 1 hit.
InterProiIPR013763. Cyclin-like.
IPR014400. Cyclin_A/B/D/E/F.
IPR015453. Cyclin_A_chordates.
IPR006671. Cyclin_N.
[Graphical view]
PANTHERiPTHR10177:SF69. PTHR10177:SF69. 1 hit.
PfamiPF00134. Cyclin_N. 1 hit.
[Graphical view]
PIRSFiPIRSF001771. Cyclin_A_B_D_E. 1 hit.
SMARTiSM00385. CYCLIN. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 1 hit.
PROSITEiPS00292. CYCLINS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q91ZX8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MPGIARQAGS ALLSQQEDQE NVNPEKVAPA QQPRAQAVLK AGKVRGPAPQ
60 70 80 90 100
QRLKTRRVAP LKDLPINDEH VPTVPSWKAV SKQPAFTIHV DEAEETQKRP
110 120 130 140 150
AERKETQCED ALAFSAAVSL PGARKPLVPL DYPMDGSFES PHAMDISIVL
160 170 180 190 200
EDEKPVNVNE VPDYHEDIHT YLGEMEVKCK PKVSYMKRQP DITNSMRAIL
210 220 230 240 250
VDWLVEVGEE YKLQNETLHL AVNYIDRFLF SMSALRGKLQ LVGTAAMLLA
260
SKFEEIYPPE VAEFV
Length:265
Mass (Da):29,619
Last modified:December 1, 2001 - v1
Checksum:iFACE7AC47D6A1289
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei265 – 2651Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367448 mRNA. Translation: AAK56923.1.
RefSeqiNP_446154.3. NM_053702.3.
UniGeneiRn.13094.

Genome annotation databases

GeneIDi114494.
KEGGirno:114494.
UCSCiRGD:621059. rat.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF367448 mRNA. Translation: AAK56923.1 .
RefSeqi NP_446154.3. NM_053702.3.
UniGenei Rn.13094.

3D structure databases

ProteinModelPortali Q91ZX8.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 114494.
KEGGi rno:114494.
UCSCi RGD:621059. rat.

Organism-specific databases

CTDi 890.
RGDi 621059. Ccna2.

Phylogenomic databases

HOVERGENi HBG106244.
KOi K06627.
PhylomeDBi Q91ZX8.

Miscellaneous databases

NextBioi 618537.

Gene expression databases

Genevestigatori Q91ZX8.

Family and domain databases

Gene3Di 1.10.472.10. 1 hit.
InterProi IPR013763. Cyclin-like.
IPR014400. Cyclin_A/B/D/E/F.
IPR015453. Cyclin_A_chordates.
IPR006671. Cyclin_N.
[Graphical view ]
PANTHERi PTHR10177:SF69. PTHR10177:SF69. 1 hit.
Pfami PF00134. Cyclin_N. 1 hit.
[Graphical view ]
PIRSFi PIRSF001771. Cyclin_A_B_D_E. 1 hit.
SMARTi SM00385. CYCLIN. 1 hit.
[Graphical view ]
SUPFAMi SSF47954. SSF47954. 1 hit.
PROSITEi PS00292. CYCLINS. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Inhibition of anchorage-independent cell growth, adhesion, and cyclin D1 gene expression by a dominant negative mutant of a tyrosine phosphatase."
    Mitra S.K., Swarup G.
    Exp. Cell Res. 270:32-44(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: LungImported.

Entry informationi

Entry nameiQ91ZX8_RAT
AccessioniPrimary (citable) accession number: Q91ZX8
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: October 29, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)