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Protein
Submitted name:

GABA theta subunit

Gene

Gabrq

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionIon channelUniRule annotationSAAS annotation
Biological processIon transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
GABA theta subunitImported
Gene namesi
Name:GabrqImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi68331 Gabrq

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei262 – 281HelicalSequence analysisAdd BLAST20
Transmembranei288 – 305HelicalSequence analysisAdd BLAST18
Transmembranei325 – 348HelicalSequence analysisAdd BLAST24
Transmembranei616 – 632HelicalSequence analysisAdd BLAST17

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL1907607

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 16Sequence analysisAdd BLAST16
ChainiPRO_500432092517 – 635Sequence analysisAdd BLAST619

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

GenevisibleiQ91ZM7 RN

Structurei

3D structure databases

ProteinModelPortaliQ91ZM7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini55 – 258Neur_chan_LBDInterPro annotationAdd BLAST204
Domaini266 – 630Neur_chan_membInterPro annotationAdd BLAST365

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3643 Eukaryota
ENOG410XPWH LUCA
HOGENOMiHOG000049189
HOVERGENiHBG051708
KOiK05192

Family and domain databases

Gene3Di2.70.170.10, 1 hit
InterProiView protein in InterPro
IPR006028 GABAA/Glycine_rcpt
IPR008101 GABAAt_rcpt
IPR006202 Neur_chan_lig-bd
IPR036734 Neur_chan_lig-bd_sf
IPR006201 Neur_channel
IPR036719 Neuro-gated_channel_TM_sf
IPR006029 Neurotrans-gated_channel_TM
IPR018000 Neurotransmitter_ion_chnl_CS
PANTHERiPTHR18945 PTHR18945, 1 hit
PfamiView protein in Pfam
PF02931 Neur_chan_LBD, 1 hit
PF02932 Neur_chan_memb, 1 hit
PRINTSiPR00253 GABAARECEPTR
PR01725 GABAARTHETA
PR00252 NRIONCHANNEL
SUPFAMiSSF63712 SSF63712, 1 hit
SSF90112 SSF90112, 2 hits
TIGRFAMsiTIGR00860 LIC, 1 hit
PROSITEiView protein in PROSITE
PS00236 NEUROTR_ION_CHANNEL, 1 hit

Sequencei

Sequence statusi: Complete.

Q91ZM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRAAELLLL IRTWLAESND PSPTPKFHFE LSSSMPEVIL DLFNCKNCAN
60 70 80 90 100
EAVVQKILDR VLSTYDVRLR PNFGGAPVPV SISIYVSSIE QISEINMDYT
110 120 130 140 150
ITMFLHQTWK DTRLAYYETN LNLTLDYRMH EKLWVPDCYF VNSKDAFVHD
160 170 180 190 200
VTAENRVFQL HPDGTVQYGI RLTTTAACSL DLQKFPMDKQ SCKLEVESYG
210 220 230 240 250
YTVEDIVLSW EDDNAIHITD ELHIPQYTYL GRTITSKEVY FYTGSYMRLI
260 270 280 290 300
VKFQVQREVR SYLVQVYWPT VLTTILSWIS FWMNYGSSAA RVTIGLTSIL
310 320 330 340 350
VLTTIDSHMR DKLPHISCIK AIDIYILVCL FFVFLSLLEY VYINYLFFSQ
360 370 380 390 400
APRRNHRRCR KPRRVVARYR YQEVVVAHVQ DGLINVEDRV EDRAGPLPDS
410 420 430 440 450
PMQAHLASQE SLGSLLFTSE EAQLATSESL SLLSSASSQV QLATGESLGD
460 470 480 490 500
LPSTSEQTLP DYTIHFHGFL TNDSILPIKI RSHSDALGDE DSEESLSSEE
510 520 530 540 550
SYGHGGSPTG RLKLQISQRC VQEASWDIDK IESLQDDISI KSSWLGLDEQ
560 570 580 590 600
RKGDADSIWS LTDEELMACD QEKDSSSSSE SEESCSPSPG CSFNEGFSFQ
610 620 630
LFNPNRVPKV DRWSRFLFPL SFGLFNVVYW LYHMY
Length:635
Mass (Da):72,568
Last modified:December 1, 2001 - v1
Checksum:iF1A814AEC1A44CD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419333 mRNA Translation: AAL15939.1
RefSeqiNP_113921.1, NM_031733.1
UniGeneiRn.81067

Genome annotation databases

GeneIDi65187
KEGGirno:65187

Similar proteinsi

Entry informationi

Entry nameiQ91ZM7_RAT
AccessioniPrimary (citable) accession number: Q91ZM7
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 111 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health