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Protein
Submitted name:

GABA theta subunit

Gene

Gabrq

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Ion channelUniRule annotationSAAS annotation

Keywords - Biological processi

Ion transport, Transport

Names & Taxonomyi

Protein namesi
Submitted name:
GABA theta subunitImported
Gene namesi
Name:GabrqImported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeRattus

Organism-specific databases

RGDi68331. Gabrq.

Subcellular locationi

  • Cell junctionsynapse SAAS annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei262 – 28120HelicalSequence analysisAdd
BLAST
Transmembranei288 – 30518HelicalSequence analysisAdd
BLAST
Transmembranei325 – 34824HelicalSequence analysisAdd
BLAST
Transmembranei616 – 63217HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell junction, Cell membraneSAAS annotation, Membrane, SynapseSAAS annotation

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL1907607.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 1616Sequence analysisAdd
BLAST
Chaini17 – 635619Sequence analysisPRO_5004320925Add
BLAST

Keywords - PTMi

Disulfide bondSAAS annotation

Proteomic databases

PaxDbiQ91ZM7.

Expressioni

Gene expression databases

GenevisibleiQ91ZM7. RN.

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022880.

Structurei

3D structure databases

ProteinModelPortaliQ91ZM7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini55 – 258204Neur_chan_LBDInterPro annotationAdd
BLAST
Domaini266 – 630365Neur_chan_membInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the ligand-gated ion channel (TC 1.A.9) family. [View classification]UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3643. Eukaryota.
ENOG410XPWH. LUCA.
HOGENOMiHOG000049189.
HOVERGENiHBG051708.
KOiK05192.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiIPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 2 hits.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 2 hits.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91ZM7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLRAAELLLL IRTWLAESND PSPTPKFHFE LSSSMPEVIL DLFNCKNCAN
60 70 80 90 100
EAVVQKILDR VLSTYDVRLR PNFGGAPVPV SISIYVSSIE QISEINMDYT
110 120 130 140 150
ITMFLHQTWK DTRLAYYETN LNLTLDYRMH EKLWVPDCYF VNSKDAFVHD
160 170 180 190 200
VTAENRVFQL HPDGTVQYGI RLTTTAACSL DLQKFPMDKQ SCKLEVESYG
210 220 230 240 250
YTVEDIVLSW EDDNAIHITD ELHIPQYTYL GRTITSKEVY FYTGSYMRLI
260 270 280 290 300
VKFQVQREVR SYLVQVYWPT VLTTILSWIS FWMNYGSSAA RVTIGLTSIL
310 320 330 340 350
VLTTIDSHMR DKLPHISCIK AIDIYILVCL FFVFLSLLEY VYINYLFFSQ
360 370 380 390 400
APRRNHRRCR KPRRVVARYR YQEVVVAHVQ DGLINVEDRV EDRAGPLPDS
410 420 430 440 450
PMQAHLASQE SLGSLLFTSE EAQLATSESL SLLSSASSQV QLATGESLGD
460 470 480 490 500
LPSTSEQTLP DYTIHFHGFL TNDSILPIKI RSHSDALGDE DSEESLSSEE
510 520 530 540 550
SYGHGGSPTG RLKLQISQRC VQEASWDIDK IESLQDDISI KSSWLGLDEQ
560 570 580 590 600
RKGDADSIWS LTDEELMACD QEKDSSSSSE SEESCSPSPG CSFNEGFSFQ
610 620 630
LFNPNRVPKV DRWSRFLFPL SFGLFNVVYW LYHMY
Length:635
Mass (Da):72,568
Last modified:December 1, 2001 - v1
Checksum:iF1A814AEC1A44CD7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419333 mRNA. Translation: AAL15939.1.
RefSeqiNP_113921.1. NM_031733.1.
UniGeneiRn.81067.

Genome annotation databases

GeneIDi65187.
KEGGirno:65187.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF419333 mRNA. Translation: AAL15939.1.
RefSeqiNP_113921.1. NM_031733.1.
UniGeneiRn.81067.

3D structure databases

ProteinModelPortaliQ91ZM7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000022880.

Chemistry

ChEMBLiCHEMBL1907607.

Proteomic databases

PaxDbiQ91ZM7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi65187.
KEGGirno:65187.

Organism-specific databases

CTDi55879.
RGDi68331. Gabrq.

Phylogenomic databases

eggNOGiKOG3643. Eukaryota.
ENOG410XPWH. LUCA.
HOGENOMiHOG000049189.
HOVERGENiHBG051708.
KOiK05192.

Gene expression databases

GenevisibleiQ91ZM7. RN.

Family and domain databases

Gene3Di2.70.170.10. 1 hit.
InterProiIPR006028. GABAA/Glycine_rcpt.
IPR008101. GABAAt_rcpt.
IPR006202. Neur_chan_lig-bd.
IPR006201. Neur_channel.
IPR006029. Neurotrans-gated_channel_TM.
IPR018000. Neurotransmitter_ion_chnl_CS.
[Graphical view]
PANTHERiPTHR18945. PTHR18945. 2 hits.
PfamiPF02931. Neur_chan_LBD. 1 hit.
PF02932. Neur_chan_memb. 1 hit.
[Graphical view]
PRINTSiPR00253. GABAARECEPTR.
PR01725. GABAARTHETA.
PR00252. NRIONCHANNEL.
SUPFAMiSSF63712. SSF63712. 1 hit.
SSF90112. SSF90112. 2 hits.
TIGRFAMsiTIGR00860. LIC. 1 hit.
PROSITEiPS00236. NEUROTR_ION_CHANNEL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91ZM7_RAT
AccessioniPrimary (citable) accession number: Q91ZM7
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: July 6, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.