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Q91ZF0 (DJC24_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified September 21, 2011. Version 83. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
DnaJ homolog subfamily C member 24
Alternative name(s):
CSL-type zinc finger-containing protein 3
DPH4 homolog
J domain protein DjC7
Gene names
Name:Dnajc24
Synonyms:Dph4, Zcsl3
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length196 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Stimulates the ATPase activity of several Hsp70-type chaperones. Ref.1

Tissue specificity

Detected in heart, brain, spleen, lung, liver, kidney and testis. Ref.1

Sequence similarities

Belongs to the DPH4 family.

Contains 1 DPH-type zinc finger.

Contains 1 J domain.

Sequence caution

The sequence AAK21968.1 differs from that shown. Reason: A nucleotide mismatch versus the mouse genome results in the formation of an upstream ATG start codon.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 196196DnaJ homolog subfamily C member 24
PRO_0000082623

Regions

Domain58 – 12972J
Zinc finger140 – 19556DPH-type

Experimental info

Sequence conflict1501S → F in AAK21968. Ref.1
Sequence conflict1941H → Q in AAK21968. Ref.1

Secondary structure

............. 196
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q91ZF0 [UniParc].

Last modified May 24, 2005. Version 2.
Checksum: 566EA6265955CD4F

FASTA19622,098
        10         20         30         40         50         60 
MTLCGARGRH QQGQPRWGGR LPVDAACPPS CGCFRVIREG SLLGQRTLMA LEQTLKKDWY 

        70         80         90        100        110        120 
SILGADPSAN MSDLKQKYQK LILLYHPDKQ SADVPAGTME ECMQKFIEID QAWKILGNEE 

       130        140        150        160        170        180 
TKKKYDLQRH EDELRNVGPV DAQVRLEEMS WNQGDESFFL SCRCGGKYTV SKDEAQEATL 

       190 
ISCDACSLIV ELLHQS 

« Hide

References

« Hide 'large scale' references
[1]"Cloning and characterization of a new soluble murine J-domain protein that stimulates BiP, Hsc70 and DnaK ATPase activity with different efficiencies."
Kroczynska B., Blond S.Y.
Gene 273:267-274(2001) [PubMed: 11595173] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, TISSUE SPECIFICITY.
Tissue: Embryo.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Testis.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J and FVB/N.
Tissue: Mammary tumor and Thymus.
[4]"Solution structure of J-domain of mouse DNAJ-like protein."
RIKEN structural genomics initiative (RSGI)
Submitted (NOV-2004) to the PDB data bank
Cited for: STRUCTURE BY NMR OF 49-129.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY028460 mRNA. Translation: AAK21968.1. Sequence problems.
AK006521 mRNA. Translation: BAB24631.1.
BC030072 mRNA. Translation: AAH30072.1.
BC091774 mRNA. Translation: AAH91774.1.
IPIIPI00605234.
RefSeqNP_081268.1. NM_026992.3.
UniGeneMm.25661.
Mm.401286.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1WJZNMR-A49-129[»]
ProteinModelPortalQ91ZF0.
SMRQ91ZF0. Positions 49-195.
ModBaseSearch...

Proteomic databases

PRIDEQ91ZF0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID99349.
KEGGmmu:99349.
NMPDRfig|10090.3.peg.6513.

Organism-specific databases

CTD120526.
MGIMGI:1919522. Dnajc24.

Phylogenomic databases

GeneTreeENSGT00390000005430.
HOGENOMHBG283742.
HOVERGENHBG066253.
InParanoidQ91ZF0.
OrthoDBEOG48KRCH.

Gene expression databases

ArrayExpressQ91ZF0.
BgeeQ91ZF0.
GenevestigatorQ91ZF0.
GermOnlineENSMUSG00000027166. Mus musculus.

Family and domain databases

InterProIPR001623. DnaJ_N.
IPR003095. Hsp_DnaJ.
IPR007872. Znf_DHP.
[Graphical view]
Gene3DG3DSA:1.10.287.110. DnaJ_N. 1 hit.
PfamPF00226. DnaJ. 1 hit.
PF05207. zf-CSL. 1 hit.
[Graphical view]
PRINTSPR00625. JDOMAIN.
SMARTSM00271. DnaJ. 1 hit.
[Graphical view]
SUPFAMSSF46565. DnaJ_N. 1 hit.
PROSITEPS00636. DNAJ_1. False negative.
PS50076. DNAJ_2. 1 hit.
PS51074. ZF_DPH. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio353889.
SOURCESearch...

Entry information

Entry nameDJC24_MOUSE
AccessionPrimary (citable) accession number: Q91ZF0
Secondary accession number(s): Q9D9S7
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: May 24, 2005
Last modified: September 21, 2011
This is version 83 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families