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Q91Z04

- Q91Z04_MOUSE

UniProt

Q91Z04 - Q91Z04_MOUSE

Protein
Submitted name:

Arhgap1 protein

Gene

Arhgap1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 62 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI
    2. Rac GTPase activator activity Source: MGI
    3. Rho GTPase activator activity Source: MGI

    GO - Biological processi

    1. positive regulation of Rac GTPase activity Source: GOC
    2. positive regulation of Rho GTPase activity Source: GOC
    3. regulation of GTPase activity Source: MGI
    4. signal transduction Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Arhgap1 proteinImported
    Gene namesi
    Name:Arhgap1Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:2445003. Arhgap1.

    Subcellular locationi

    GO - Cellular componenti

    1. cell leading edge Source: MGI
    2. intracellular Source: InterPro
    3. plasma membrane Source: MGI
    4. ruffle Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ91Z04.

    Structurei

    3D structure databases

    ProteinModelPortaliQ91Z04.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG054433.
    InParanoidiQ91Z04.

    Family and domain databases

    Gene3Di1.10.555.10. 1 hit.
    InterProiIPR008936. Rho_GTPase_activation_prot.
    IPR000198. RhoGAP_dom.
    [Graphical view]
    PfamiPF00620. RhoGAP. 1 hit.
    [Graphical view]
    SMARTiSM00324. RhoGAP. 1 hit.
    [Graphical view]
    SUPFAMiSSF48350. SSF48350. 1 hit.
    PROSITEiPS50238. RHOGAP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q91Z04-1 [UniParc]FASTAAdd to Basket

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    KSPGQEPIPI VLRETVAYLQ AHALTTEGIF RRSANTQVVR EVQQKYNMGL    50
    PVDFDQYNEL HLPAVILKTF LRELPEPLLT FDLYPHVVGF LNIDESQRVE 100
    VTQQVLQTLP EENYQVLHFL TAFLVQISAH CDQNKMTNTN LAVVFGPNLL 150
    WAKDAAITLK AINPINTFTK FLLDHQGELF PSTDAQGV 188
    Length:188
    Mass (Da):21,282
    Last modified:December 1, 2001 - v1
    Checksum:i8BF5954C6457FB73
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC010328 mRNA. Translation: AAH10328.1.
    UniGeneiMm.22413.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BC010328 mRNA. Translation: AAH10328.1 .
    UniGenei Mm.22413.

    3D structure databases

    ProteinModelPortali Q91Z04.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:2445003. Arhgap1.

    Phylogenomic databases

    HOVERGENi HBG054433.
    InParanoidi Q91Z04.

    Miscellaneous databases

    ChiTaRSi ARHGAP1. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q91Z04.

    Family and domain databases

    Gene3Di 1.10.555.10. 1 hit.
    InterProi IPR008936. Rho_GTPase_activation_prot.
    IPR000198. RhoGAP_dom.
    [Graphical view ]
    Pfami PF00620. RhoGAP. 1 hit.
    [Graphical view ]
    SMARTi SM00324. RhoGAP. 1 hit.
    [Graphical view ]
    SUPFAMi SSF48350. SSF48350. 1 hit.
    PROSITEi PS50238. RHOGAP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/NImported.
      Tissue: Mammary tumor. Metallothionien-TGF alpha model. 10 month old virgin mouse. Taken by biopsy.Imported.

    Entry informationi

    Entry nameiQ91Z04_MOUSE
    AccessioniPrimary (citable) accession number: Q91Z04
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 1, 2001
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 62 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)