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Protein

ATP synthase mitochondrial F1 complex assembly factor 2

Gene

Atpaf2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in the assembly of the F1 component of the mitochondrial ATP synthase (ATPase).By similarity

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Chaperone

Names & Taxonomyi

Protein namesi
Recommended name:
ATP synthase mitochondrial F1 complex assembly factor 2
Gene namesi
Name:Atpaf2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Unplaced

Organism-specific databases

MGIiMGI:2180561. Atpaf2.

Subcellular locationi

GO - Cellular componenti

  • cytoplasm Source: MGI
  • mitochondrion Source: MGI
  • nuclear speck Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4040MitochondrionSequence analysisAdd
BLAST
Chaini41 – 289249ATP synthase mitochondrial F1 complex assembly factor 2PRO_0000002419Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei133 – 1331N6-succinyllysineCombined sources

Proteomic databases

EPDiQ91YY4.
MaxQBiQ91YY4.
PaxDbiQ91YY4.
PeptideAtlasiQ91YY4.
PRIDEiQ91YY4.

PTM databases

iPTMnetiQ91YY4.
PhosphoSiteiQ91YY4.

Expressioni

Gene expression databases

BgeeiENSMUSG00000042709.

Interactioni

Subunit structurei

Interacts with ATP5A1.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104361.

Structurei

3D structure databases

ProteinModelPortaliQ91YY4.
SMRiQ91YY4. Positions 47-264.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ATP12 family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiKOG3015. Eukaryota.
COG5387. LUCA.
HOGENOMiHOG000139577.
HOVERGENiHBG063751.
InParanoidiQ91YY4.
KOiK07556.
PhylomeDBiQ91YY4.
TreeFamiTF315138.

Family and domain databases

Gene3Di1.10.3580.10. 1 hit.
InterProiIPR011419. ATP12_ATPase-F1F0-assembly.
IPR023335. ATPase_assmbl_ATP12_dom.
[Graphical view]
PANTHERiPTHR21013. PTHR21013. 1 hit.
PfamiPF07542. ATP12. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q91YY4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MWRIYPRLRD RWRGLLDRRL SDPTVSVWPG PAPQPPARAY VPPTERKRFY
60 70 80 90 100
QNVSISQGEG GFEINLDHRK LKTPQAKLFT VPSEALAIAV ATEWDSQQDT
110 120 130 140 150
IKFYTMHLTT LCNTSLDNPT QRSKDQLIRA AVKFLDTDTI CYRVEEPETL
160 170 180 190 200
VELQKNEWDP VIEWAEKRYG MEIGSSTSIM GPSIPTQTRE VLTSHLSSYN
210 220 230 240 250
MWALQGIEFV VAQLKSMLLT LGLIDLRLTV EQAVLLSRLE EEYQIQKWGN
260 270 280
IEWAHDYELQ ELRARTAAGT LFVHLCSESS TVKHKLLQE
Length:289
Mass (Da):33,289
Last modified:December 1, 2001 - v1
Checksum:iF9644CF4189AC466
GO

Sequence cautioni

The sequence BAC37311 differs from that shown. Reason: Erroneous initiation. Curated
The sequence CAI24077 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078500 mRNA. Translation: BAC37311.1. Different initiation.
AL596090 Genomic DNA. Translation: CAI24077.1. Different initiation.
BC013607 mRNA. Translation: AAH13607.1.
RefSeqiNP_663402.2. NM_145427.2.
UniGeneiMm.41651.
Mm.475062.

Genome annotation databases

GeneIDi246782.
KEGGimmu:246782.
UCSCiuc007jfv.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK078500 mRNA. Translation: BAC37311.1. Different initiation.
AL596090 Genomic DNA. Translation: CAI24077.1. Different initiation.
BC013607 mRNA. Translation: AAH13607.1.
RefSeqiNP_663402.2. NM_145427.2.
UniGeneiMm.41651.
Mm.475062.

3D structure databases

ProteinModelPortaliQ91YY4.
SMRiQ91YY4. Positions 47-264.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000104361.

PTM databases

iPTMnetiQ91YY4.
PhosphoSiteiQ91YY4.

Proteomic databases

EPDiQ91YY4.
MaxQBiQ91YY4.
PaxDbiQ91YY4.
PeptideAtlasiQ91YY4.
PRIDEiQ91YY4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi246782.
KEGGimmu:246782.
UCSCiuc007jfv.2. mouse.

Organism-specific databases

CTDi91647.
MGIiMGI:2180561. Atpaf2.

Phylogenomic databases

eggNOGiKOG3015. Eukaryota.
COG5387. LUCA.
HOGENOMiHOG000139577.
HOVERGENiHBG063751.
InParanoidiQ91YY4.
KOiK07556.
PhylomeDBiQ91YY4.
TreeFamiTF315138.

Miscellaneous databases

ChiTaRSiAtpaf2. mouse.
PROiQ91YY4.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000042709.

Family and domain databases

Gene3Di1.10.3580.10. 1 hit.
InterProiIPR011419. ATP12_ATPase-F1F0-assembly.
IPR023335. ATPase_assmbl_ATP12_dom.
[Graphical view]
PANTHERiPTHR21013. PTHR21013. 1 hit.
PfamiPF07542. ATP12. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiATPF2_MOUSE
AccessioniPrimary (citable) accession number: Q91YY4
Secondary accession number(s): Q8BP08
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: December 1, 2001
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.