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Protein
Submitted name:

Kinesin light chain 2

Gene

Klc2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-2132295. MHC class II antigen presentation.
R-MMU-5625970. RHO GTPases activate KTN1.
R-MMU-6811434. COPI-dependent Golgi-to-ER retrograde traffic.
R-MMU-983189. Kinesins.

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin light chain 2Imported
Submitted name:
Klc2 proteinImported
Gene namesi
Name:Klc2Imported
ORF Names:mCG_8395Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:107953. Klc2.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000024862.

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-61735N.
MINTiMINT-4122066.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini198 – 399TPR_REGIONInterPro annotationAdd BLAST202
Repeati198 – 231TPRPROSITE-ProRule annotationAdd BLAST34
Repeati240 – 273TPRPROSITE-ProRule annotationAdd BLAST34
Repeati282 – 315TPRPROSITE-ProRule annotationAdd BLAST34
Repeati324 – 357TPRPROSITE-ProRule annotationAdd BLAST34
Repeati366 – 399TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili85 – 140Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1840. Eukaryota.
COG0457. LUCA.
GeneTreeiENSGT00390000006393.
HOGENOMiHOG000261663.
HOVERGENiHBG006217.
KOiK10407.
OMAiGPQEPRN.
OrthoDBiEOG091G05DM.
TreeFamiTF314010.

Family and domain databases

Gene3Di1.10.10.10. 5 hits.
InterProiView protein in InterPro
IPR002151. Kinesin_light.
IPR015792. Kinesin_light_repeat.
IPR013026. TPR-contain_dom.
IPR011990. TPR-like_helical_dom_sf.
IPR019734. TPR_repeat.
IPR036388. WH-like_DNA-bd_sf.
PRINTSiPR00381. KINESINLIGHT.
SMARTiView protein in SMART
SM00028. TPR. 4 hits.
SUPFAMiSSF48452. SSF48452. 3 hits.
PROSITEiView protein in PROSITE
PS01160. KINESIN_LIGHT. 1 hit.
PS50005. TPR. 5 hits.
PS50293. TPR_REGION. 1 hit.

Sequencei

Sequence statusi: Complete.

Q91YS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATMVLPREE KLSQDEIVLG TKAVIQGLET LRGEHRALLA PLASHEAGEA
60 70 80 90 100
EPGSQERCLL LRRSLEAIEL GLGEAQVILA LSSHLGAVES EKQKLRAQVR
110 120 130 140 150
RLVQENQWLR EELAGTQQKL QRSEQAVAQL EEEKQHLLFM SQIRKLDEDA
160 170 180 190 200
SPNEEKGDVP KDSLDDLFPN EDEQSPAPSP GGGDVAAQHG GYEIPARLRT
210 220 230 240 250
LHNLVIQYAS QGRYEVAVPL CKQALEDLEK TSGHDHPDVA TMLNILALVY
260 270 280 290 300
RDQNKYKDAA HLLNDALAIR EKTLGKDHPA VAATLNNLAV LYGKRGKYKE
310 320 330 340 350
AEPLCKRALE IREKVLGKFH PDVAKQLSNL ALLCQNQGKA EEVEYYYRRA
360 370 380 390 400
LEIYATRLGP DDPNVAKTKN NLASCYLKQG KYQDAETLYK EILTRAHEKE
410 420 430 440 450
FGSVNGENKP IWMHAEEREE SKDKRRDSAP YGEYGSWYKA CKVDSPTVNT
460 470 480 490 500
TLRSLGALYR RQGKLEAAHT LEDCASRSRK QGLDPASQTK VVELLKDGSG
510 520 530 540 550
GRGHRRGSRD VAGPQSESDL EESGPAAEWS GDGSGSLRRS GSFGKLRDAL
560 570 580 590 600
RRSSEMLVRK LQGGGPQEPP NSRMKRASSL NFLNKSVEEP VQPGGTGLSD
610
SRTLSSSSMD LSRRSSLVG
Length:619
Mass (Da):68,420
Last modified:December 1, 2001 - v1
Checksum:iA3C2B941BECDB178
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124502 Genomic DNA. No translation available.
BC014845 mRNA. Translation: AAH14845.1.
CH466612 Genomic DNA. Translation: EDL33106.1.
RefSeqiNP_032477.2. NM_008451.2.
XP_011246905.1. XM_011248603.2.
UniGeneiMm.271648.

Genome annotation databases

EnsembliENSMUST00000116563; ENSMUSP00000112262; ENSMUSG00000024862.
GeneIDi16594.
KEGGimmu:16594.
UCSCiuc008gcg.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ91YS4_MOUSE
AccessioniPrimary (citable) accession number: Q91YS4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 22, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported