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Protein
Submitted name:

Kinesin light chain 2

Gene

Klc2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Enzyme and pathway databases

ReactomeiR-MMU-2132295 MHC class II antigen presentation
R-MMU-5625970 RHO GTPases activate KTN1
R-MMU-6811434 COPI-dependent Golgi-to-ER retrograde traffic
R-MMU-983189 Kinesins

Names & Taxonomyi

Protein namesi
Submitted name:
Kinesin light chain 2Imported
Submitted name:
Klc2 proteinImported
Gene namesi
Name:Klc2Imported
ORF Names:mCG_8395Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:107953 Klc2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSMUSG00000024862

Interactioni

Binary interactionsi

Show more details

GO - Molecular functioni

Protein-protein interaction databases

DIPiDIP-61735N

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5OJFX-ray3.40A/B/C190-484[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini198 – 399TPR_REGIONInterPro annotationAdd BLAST202
Repeati198 – 231TPRPROSITE-ProRule annotationAdd BLAST34
Repeati240 – 273TPRPROSITE-ProRule annotationAdd BLAST34
Repeati282 – 315TPRPROSITE-ProRule annotationAdd BLAST34
Repeati324 – 357TPRPROSITE-ProRule annotationAdd BLAST34
Repeati366 – 399TPRPROSITE-ProRule annotationAdd BLAST34

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili85 – 140Sequence analysisAdd BLAST56

Keywords - Domaini

Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1840 Eukaryota
COG0457 LUCA
GeneTreeiENSGT00390000006393
HOGENOMiHOG000261663
HOVERGENiHBG006217
KOiK10407
OMAiGPQEPRN
OrthoDBiEOG091G05DM
TreeFamiTF314010

Family and domain databases

Gene3Di1.25.40.101 hit
InterProiView protein in InterPro
IPR002151 Kinesin_light
IPR015792 Kinesin_light_repeat
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PRINTSiPR00381 KINESINLIGHT
SMARTiView protein in SMART
SM00028 TPR, 4 hits
SUPFAMiSSF48452 SSF48452, 3 hits
PROSITEiView protein in PROSITE
PS01160 KINESIN_LIGHT, 1 hit
PS50005 TPR, 5 hits
PS50293 TPR_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Q91YS4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATMVLPREE KLSQDEIVLG TKAVIQGLET LRGEHRALLA PLASHEAGEA
60 70 80 90 100
EPGSQERCLL LRRSLEAIEL GLGEAQVILA LSSHLGAVES EKQKLRAQVR
110 120 130 140 150
RLVQENQWLR EELAGTQQKL QRSEQAVAQL EEEKQHLLFM SQIRKLDEDA
160 170 180 190 200
SPNEEKGDVP KDSLDDLFPN EDEQSPAPSP GGGDVAAQHG GYEIPARLRT
210 220 230 240 250
LHNLVIQYAS QGRYEVAVPL CKQALEDLEK TSGHDHPDVA TMLNILALVY
260 270 280 290 300
RDQNKYKDAA HLLNDALAIR EKTLGKDHPA VAATLNNLAV LYGKRGKYKE
310 320 330 340 350
AEPLCKRALE IREKVLGKFH PDVAKQLSNL ALLCQNQGKA EEVEYYYRRA
360 370 380 390 400
LEIYATRLGP DDPNVAKTKN NLASCYLKQG KYQDAETLYK EILTRAHEKE
410 420 430 440 450
FGSVNGENKP IWMHAEEREE SKDKRRDSAP YGEYGSWYKA CKVDSPTVNT
460 470 480 490 500
TLRSLGALYR RQGKLEAAHT LEDCASRSRK QGLDPASQTK VVELLKDGSG
510 520 530 540 550
GRGHRRGSRD VAGPQSESDL EESGPAAEWS GDGSGSLRRS GSFGKLRDAL
560 570 580 590 600
RRSSEMLVRK LQGGGPQEPP NSRMKRASSL NFLNKSVEEP VQPGGTGLSD
610
SRTLSSSSMD LSRRSSLVG
Length:619
Mass (Da):68,420
Last modified:December 1, 2001 - v1
Checksum:iA3C2B941BECDB178
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124502 Genomic DNA No translation available.
BC014845 mRNA Translation: AAH14845.1
CH466612 Genomic DNA Translation: EDL33106.1
RefSeqiNP_032477.2, NM_008451.2
XP_011246905.1, XM_011248603.2
UniGeneiMm.271648

Genome annotation databases

EnsembliENSMUST00000116563; ENSMUSP00000112262; ENSMUSG00000024862
GeneIDi16594
KEGGimmu:16594
UCSCiuc008gcg.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ91YS4_MOUSE
AccessioniPrimary (citable) accession number: Q91YS4
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: April 25, 2018
This is version 130 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported