Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribosomal RNA processing protein 1 homolog B

Gene

Rrp1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA processing protein 1 homolog B
Alternative name(s):
RRP1-like protein B
Gene namesi
Name:Rrp1b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 17

Organism-specific databases

MGIiMGI:1919712. Rrp1b.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: MGI
  • euchromatin Source: MGI
  • heterochromatin Source: MGI
  • nucleolus Source: MGI
  • nucleus Source: MGI
  • preribosome, large subunit precursor Source: GO_Central
  • preribosome, small subunit precursor Source: InterPro
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003401161 – 724Ribosomal RNA processing protein 1 homolog BAdd BLAST724

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei336PhosphoserineBy similarity1
Modified residuei370PhosphoserineBy similarity1
Modified residuei432PhosphoserineBy similarity1
Modified residuei438PhosphoserineBy similarity1
Modified residuei494PhosphoserineBy similarity1
Modified residuei618N6-acetyllysineBy similarity1
Modified residuei668PhosphoserineBy similarity1
Modified residuei672PhosphoserineBy similarity1
Modified residuei678Citrulline1 Publication1
Modified residuei694PhosphothreonineBy similarity1
Modified residuei698PhosphoserineBy similarity1
Modified residuei701PhosphoserineBy similarity1

Post-translational modificationi

Citrullinated by PADI4.1 Publication

Keywords - PTMi

Acetylation, Citrullination, Phosphoprotein

Proteomic databases

EPDiQ91YK2.
MaxQBiQ91YK2.
PaxDbiQ91YK2.
PeptideAtlasiQ91YK2.
PRIDEiQ91YK2.

PTM databases

iPTMnetiQ91YK2.
PhosphoSitePlusiQ91YK2.

Expressioni

Gene expression databases

BgeeiENSMUSG00000058392.
ExpressionAtlasiQ91YK2. baseline and differential.
GenevisibleiQ91YK2. MM.

Interactioni

Protein-protein interaction databases

BioGridi215383. 46 interactors.
IntActiQ91YK2. 2 interactors.
MINTiMINT-4121923.
STRINGi10090.ENSMUSP00000080085.

Structurei

3D structure databases

ProteinModelPortaliQ91YK2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RRP1 family.Curated

Phylogenomic databases

eggNOGiKOG3911. Eukaryota.
ENOG4111GJ6. LUCA.
GeneTreeiENSGT00390000011821.
HOGENOMiHOG000070179.
HOVERGENiHBG098014.
InParanoidiQ91YK2.
KOiK14849.
OMAiAFNPEQR.
OrthoDBiEOG091G0AX5.
PhylomeDBiQ91YK2.
TreeFamiTF315294.

Family and domain databases

InterProiIPR010301. Nop52.
[Graphical view]
PANTHERiPTHR13026. PTHR13026. 1 hit.
PfamiPF05997. Nop52. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91YK2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALAMQSSEF QFAQRLASSE KGVRDRAVRK LRQYLSARTQ SDTGSFSQEE
60 70 80 90 100
LLKIWKGLFY CMWVQDEPLL QEELANIISQ LIHVVNSLEA QYLFIQTFWQ
110 120 130 140 150
TMNREWQGID KLQLDKYYML IRLVLRQSFE VLKRNAWEES QITLFLDILM
160 170 180 190 200
KEILSPESQS PNGVRTHLID VYLEELTTVG GAELLADQNL KLIDPFCRIA
210 220 230 240 250
AKTKDHTLVQ TVARGVFEVI VDQSACVPQE SVEERKTKED GSGFPTKALA
260 270 280 290 300
CRKAVSGKKA ALDECLRDGV IGSRERDICA ALKDSGSPLQ FDYKAVADRL
310 320 330 340 350
LEIANSKSTP PFNRKRLCRL VRKFQDLCEG NGAPLSSAED NGQRRHKRKR
360 370 380 390 400
KKLLESEKGD TVSPAAEEDS GGHIHKKKRK KRKRSHFQPD TQNLDAVAVP
410 420 430 440 450
KVPDSESEPD TAQRQAPCGQ ACVTEPTAEA VSSIGENSSK PTPVMPIHNK
460 470 480 490 500
RKRPRKKKLR AHKEICKSTT LPQEDMSKND AVSGHSQSSA AHISSSEGVQ
510 520 530 540 550
AQKRKRKLGA LPDSSSDLPV QKSGTPTSPV EGKDGQTTLP RCKRSQKKTA
560 570 580 590 600
SSTLDPCDPS SQKPAISKKK KKTMKLMSNG VLESNPGQIQ ALGSNRTLKK
610 620 630 640 650
PLKTEDDFVK FDTRFLPKPL FFRKAKNSSA TRPQGPAGQL NKTPSSSKKV
660 670 680 690 700
TFGLNRNMTA EFKKTDKSIL VSPTGLSRVA FNPEQRPLHG VLKTATSSPA
710 720
STPLSPMRLP ATTPKRRPRA ADFF
Length:724
Mass (Da):80,582
Last modified:June 10, 2008 - v2
Checksum:i4DEFC78AADBA38F1
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti209V → A in AAH16569 (PubMed:15489334).Curated1
Sequence conflicti229Q → E in AAH16569 (PubMed:15489334).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT033797 Genomic DNA. Translation: CAQ11869.1.
BC016569 mRNA. Translation: AAH16569.1.
CCDSiCCDS28613.1.
RefSeqiNP_082520.2. NM_028244.2.
UniGeneiMm.102761.

Genome annotation databases

EnsembliENSMUST00000081339; ENSMUSP00000080085; ENSMUSG00000058392.
GeneIDi72462.
KEGGimmu:72462.
UCSCiuc008bvt.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CT033797 Genomic DNA. Translation: CAQ11869.1.
BC016569 mRNA. Translation: AAH16569.1.
CCDSiCCDS28613.1.
RefSeqiNP_082520.2. NM_028244.2.
UniGeneiMm.102761.

3D structure databases

ProteinModelPortaliQ91YK2.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi215383. 46 interactors.
IntActiQ91YK2. 2 interactors.
MINTiMINT-4121923.
STRINGi10090.ENSMUSP00000080085.

PTM databases

iPTMnetiQ91YK2.
PhosphoSitePlusiQ91YK2.

Proteomic databases

EPDiQ91YK2.
MaxQBiQ91YK2.
PaxDbiQ91YK2.
PeptideAtlasiQ91YK2.
PRIDEiQ91YK2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000081339; ENSMUSP00000080085; ENSMUSG00000058392.
GeneIDi72462.
KEGGimmu:72462.
UCSCiuc008bvt.2. mouse.

Organism-specific databases

CTDi23076.
MGIiMGI:1919712. Rrp1b.

Phylogenomic databases

eggNOGiKOG3911. Eukaryota.
ENOG4111GJ6. LUCA.
GeneTreeiENSGT00390000011821.
HOGENOMiHOG000070179.
HOVERGENiHBG098014.
InParanoidiQ91YK2.
KOiK14849.
OMAiAFNPEQR.
OrthoDBiEOG091G0AX5.
PhylomeDBiQ91YK2.
TreeFamiTF315294.

Miscellaneous databases

PROiQ91YK2.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000058392.
ExpressionAtlasiQ91YK2. baseline and differential.
GenevisibleiQ91YK2. MM.

Family and domain databases

InterProiIPR010301. Nop52.
[Graphical view]
PANTHERiPTHR13026. PTHR13026. 1 hit.
PfamiPF05997. Nop52. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRRP1B_MOUSE
AccessioniPrimary (citable) accession number: Q91YK2
Secondary accession number(s): B0V2W7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: June 10, 2008
Last sequence update: June 10, 2008
Last modified: November 2, 2016
This is version 101 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.