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Q91YK2

- RRP1B_MOUSE

UniProt

Q91YK2 - RRP1B_MOUSE

Protein

Ribosomal RNA processing protein 1 homolog B

Gene

Rrp1b

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 4 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 85 (01 Oct 2014)
      Sequence version 2 (10 Jun 2008)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. negative regulation of phosphatase activity Source: UniProtKB
    2. rRNA processing Source: InterPro

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribosomal RNA processing protein 1 homolog B
    Alternative name(s):
    RRP1-like protein B
    Gene namesi
    Name:Rrp1b
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 17

    Organism-specific databases

    MGIiMGI:1919712. Rrp1b.

    Subcellular locationi

    Nucleusnucleolus By similarity

    GO - Cellular componenti

    1. cytosol Source: Ensembl
    2. euchromatin Source: MGI
    3. heterochromatin Source: MGI
    4. nucleolus Source: UniProtKB-SubCell
    5. nucleus Source: MGI
    6. preribosome, small subunit precursor Source: InterPro

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 724724Ribosomal RNA processing protein 1 homolog BPRO_0000340116Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei336 – 3361PhosphoserineBy similarity
    Modified residuei370 – 3701PhosphoserineBy similarity
    Modified residuei432 – 4321PhosphoserineBy similarity
    Modified residuei438 – 4381PhosphoserineBy similarity
    Modified residuei494 – 4941PhosphoserineBy similarity
    Modified residuei618 – 6181N6-acetyllysineBy similarity
    Modified residuei668 – 6681PhosphoserineBy similarity
    Modified residuei672 – 6721PhosphoserineBy similarity
    Modified residuei678 – 6781Citrulline1 Publication
    Modified residuei694 – 6941PhosphothreonineBy similarity
    Modified residuei698 – 6981PhosphoserineBy similarity
    Modified residuei701 – 7011PhosphoserineBy similarity

    Post-translational modificationi

    Citrullinated by PADI4.1 Publication

    Keywords - PTMi

    Acetylation, Citrullination, Phosphoprotein

    Proteomic databases

    MaxQBiQ91YK2.
    PaxDbiQ91YK2.
    PRIDEiQ91YK2.

    PTM databases

    PhosphoSiteiQ91YK2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ91YK2.
    BgeeiQ91YK2.
    GenevestigatoriQ91YK2.

    Interactioni

    Protein-protein interaction databases

    BioGridi215383. 45 interactions.
    IntActiQ91YK2. 2 interactions.
    MINTiMINT-4121923.

    Structurei

    3D structure databases

    ProteinModelPortaliQ91YK2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the RRP1 family.Curated

    Phylogenomic databases

    eggNOGiNOG299406.
    GeneTreeiENSGT00390000011821.
    HOGENOMiHOG000070179.
    HOVERGENiHBG098014.
    InParanoidiQ91YK2.
    KOiK14849.
    OMAiMTAEFKK.
    OrthoDBiEOG718KC8.
    PhylomeDBiQ91YK2.
    TreeFamiTF315294.

    Family and domain databases

    InterProiIPR010301. Nop52.
    [Graphical view]
    PANTHERiPTHR13026. PTHR13026. 1 hit.
    PfamiPF05997. Nop52. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q91YK2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MALAMQSSEF QFAQRLASSE KGVRDRAVRK LRQYLSARTQ SDTGSFSQEE    50
    LLKIWKGLFY CMWVQDEPLL QEELANIISQ LIHVVNSLEA QYLFIQTFWQ 100
    TMNREWQGID KLQLDKYYML IRLVLRQSFE VLKRNAWEES QITLFLDILM 150
    KEILSPESQS PNGVRTHLID VYLEELTTVG GAELLADQNL KLIDPFCRIA 200
    AKTKDHTLVQ TVARGVFEVI VDQSACVPQE SVEERKTKED GSGFPTKALA 250
    CRKAVSGKKA ALDECLRDGV IGSRERDICA ALKDSGSPLQ FDYKAVADRL 300
    LEIANSKSTP PFNRKRLCRL VRKFQDLCEG NGAPLSSAED NGQRRHKRKR 350
    KKLLESEKGD TVSPAAEEDS GGHIHKKKRK KRKRSHFQPD TQNLDAVAVP 400
    KVPDSESEPD TAQRQAPCGQ ACVTEPTAEA VSSIGENSSK PTPVMPIHNK 450
    RKRPRKKKLR AHKEICKSTT LPQEDMSKND AVSGHSQSSA AHISSSEGVQ 500
    AQKRKRKLGA LPDSSSDLPV QKSGTPTSPV EGKDGQTTLP RCKRSQKKTA 550
    SSTLDPCDPS SQKPAISKKK KKTMKLMSNG VLESNPGQIQ ALGSNRTLKK 600
    PLKTEDDFVK FDTRFLPKPL FFRKAKNSSA TRPQGPAGQL NKTPSSSKKV 650
    TFGLNRNMTA EFKKTDKSIL VSPTGLSRVA FNPEQRPLHG VLKTATSSPA 700
    STPLSPMRLP ATTPKRRPRA ADFF 724
    Length:724
    Mass (Da):80,582
    Last modified:June 10, 2008 - v2
    Checksum:i4DEFC78AADBA38F1
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti209 – 2091V → A in AAH16569. (PubMed:15489334)Curated
    Sequence conflicti229 – 2291Q → E in AAH16569. (PubMed:15489334)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT033797 Genomic DNA. Translation: CAQ11869.1.
    BC016569 mRNA. Translation: AAH16569.1.
    CCDSiCCDS28613.1.
    RefSeqiNP_082520.2. NM_028244.2.
    UniGeneiMm.102761.

    Genome annotation databases

    EnsembliENSMUST00000081339; ENSMUSP00000080085; ENSMUSG00000058392.
    GeneIDi72462.
    KEGGimmu:72462.
    UCSCiuc008bvt.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CT033797 Genomic DNA. Translation: CAQ11869.1 .
    BC016569 mRNA. Translation: AAH16569.1 .
    CCDSi CCDS28613.1.
    RefSeqi NP_082520.2. NM_028244.2.
    UniGenei Mm.102761.

    3D structure databases

    ProteinModelPortali Q91YK2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 215383. 45 interactions.
    IntActi Q91YK2. 2 interactions.
    MINTi MINT-4121923.

    PTM databases

    PhosphoSitei Q91YK2.

    Proteomic databases

    MaxQBi Q91YK2.
    PaxDbi Q91YK2.
    PRIDEi Q91YK2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000081339 ; ENSMUSP00000080085 ; ENSMUSG00000058392 .
    GeneIDi 72462.
    KEGGi mmu:72462.
    UCSCi uc008bvt.2. mouse.

    Organism-specific databases

    CTDi 23076.
    MGIi MGI:1919712. Rrp1b.

    Phylogenomic databases

    eggNOGi NOG299406.
    GeneTreei ENSGT00390000011821.
    HOGENOMi HOG000070179.
    HOVERGENi HBG098014.
    InParanoidi Q91YK2.
    KOi K14849.
    OMAi MTAEFKK.
    OrthoDBi EOG718KC8.
    PhylomeDBi Q91YK2.
    TreeFami TF315294.

    Miscellaneous databases

    ChiTaRSi RRP1B. mouse.
    NextBioi 336284.
    PROi Q91YK2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q91YK2.
    Bgeei Q91YK2.
    Genevestigatori Q91YK2.

    Family and domain databases

    InterProi IPR010301. Nop52.
    [Graphical view ]
    PANTHERi PTHR13026. PTHR13026. 1 hit.
    Pfami PF05997. Nop52. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary tumor.
    3. Cited for: CITRULLINATION AT ARG-678.

    Entry informationi

    Entry nameiRRP1B_MOUSE
    AccessioniPrimary (citable) accession number: Q91YK2
    Secondary accession number(s): B0V2W7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: June 10, 2008
    Last sequence update: June 10, 2008
    Last modified: October 1, 2014
    This is version 85 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3