Pcdhb15

Functionⁱ

GO - Molecular functionⁱ

calcium ion binding Source: InterPro

GO - Biological processⁱ

cell adhesion Source: GO_Central
chemical synaptic transmission Source: GO_Central
homophilic cell adhesion via plasma membrane adhesion molecules Source: InterPro
synapse assembly Source: GO_Central

Keywordsⁱ

Biological process	Cell adhesionSAAS annotation
Ligand	CalciumSAAS annotation

Names & Taxonomyⁱ

Protein namesⁱ	Submitted name: Protocadherin beta 15Imported Submitted name: Putative uncharacterized proteinImported
Gene namesⁱ	Name:Pcdhb15Imported ORF Names:mCG_141293Imported
Organismⁱ	Mus musculus (Mouse)
Taxonomic identifierⁱ	10090 [NCBI]
Taxonomic lineageⁱ	cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Dipnotetrapodomorpha › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Boreoeutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesⁱ	UP000000589 Componentⁱ: Chromosome 18

Organism-specific databases

MGIⁱ	MGI:2136750. Pcdhb15.

Subcellular locationⁱ

Topology

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Transmembraneⁱ	687 – 710	HelicalSequence analysisAdd BLAST		24

GO - Cellular componentⁱ

integral component of plasma membrane Source: GO_Central

Complete GO annotation...

Keywords - Cellular componentⁱ

Membrane

PTM / Processingⁱ

Molecule processing

Feature key	Position(s)	DescriptionActions	Graphical view	Length
Signal peptideⁱ	1 – 28	Sequence analysisAdd BLAST		28
ChainⁱPRO_5010684913	29 – 786	Sequence analysisAdd BLAST		758

Expressionⁱ

Gene expression databases

Bgeeⁱ	ENSMUSG00000047033.

Bgeeⁱ

ENSMUSG00000047033.

Interactionⁱ

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000059598.

STRINGⁱ

10090.ENSMUSP00000059598.

Family & Domainsⁱ

Domains and Repeats

Feature key	Position(s)	DescriptionActions	Length
Domainⁱ	155 – 240	CAInterPro annotationAdd BLAST	86
Domainⁱ	264 – 345	CAInterPro annotationAdd BLAST	82
Domainⁱ	368 – 449	CAInterPro annotationAdd BLAST	82
Domainⁱ	473 – 559	CAInterPro annotationAdd BLAST	87
Domainⁱ	589 – 670	CAInterPro annotationAdd BLAST	82

Keywords - Domainⁱ

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGⁱ	KOG3594. Eukaryota. ENOG410XQHI. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00840000129690.
HOVERGENⁱ	HBG054878.
KEGG Orthology (KO) More...KOⁱ	K16494.
OMAⁱ	NAKMVCS.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G024L.
TreeFamⁱ	TF332299.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002126. Cadherin. IPR015919. Cadherin-like. IPR032455. Cadherin_C. IPR020894. Cadherin_CS. IPR013164. Cadherin_N. IPR030741. PCDHB7.
PANTHERⁱ	PTHR24028:SF148. PTHR24028:SF148. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00028. Cadherin. 5 hits. PF08266. Cadherin_2. 1 hit. PF16492. Cadherin_C_2. 1 hit.
PRINTSⁱ	PR00205. CADHERIN.
SMARTⁱ	View protein in SMART SM00112. CA. 5 hits.
SUPFAMⁱ	SSF49313. SSF49313. 6 hits.
PROSITEⁱ	View protein in PROSITE PS00232. CADHERIN_1. 3 hits.

Sequenceⁱ

Sequence statusⁱ: Complete.

Q91Y04-1 [UniParc]FASTA Add to basket

« Hide

        10         20         30         40         50
MEARLEQAVQ KRQVLFLYVF LGASWASAEQ LQYSVAEETE RGTFLANLAK 
        60         70         80         90        100
DLGLGLGELS AREARIVSDQ NTRFLLLSPL TGELILNEKL DREELCGPTE 
       110        120        130        140        150
PCVLTFQLLL ERPFQIYRAA LHIKDINDNS PVFLDKEILL KISESTTPGA 
       160        170        180        190        200
TLLLERAQDA DVGTNSLSNY TISPNDYFHI HVHDGGEGPI IPELVLDKML 
       210        220        230        240        250
DREEIPEFTL TLTALDGGSP PRSGTALVQI LVLDINDNSP QFVQSLYKVQ 
       260        270        280        290        300
SPENTPVGSL VVAVSARDLD TGSYGQIDYT FFYATERILQ TFQINSTSGE 
       310        320        330        340        350
LYLKRELNYE AIQTYSITIQ ARDGGGLSGK CAVVVEVMDV NDNPPEFLLS 
       360        370        380        390        400
SLNSPIPENS QETVVAVFKI RDRDSGNNGK TLCSIANDLP FVLKPSVENF 
       410        420        430        440        450
YTLVTEKPLD RESNTEYNIT ITVTDMGIPR LTTQHTITVQ VSDINDNAPT 
       460        470        480        490        500
FTQTSYTMFV RENNSPALHI GTISATDSDS GSNAHITYSL RLPHDPQLAL 
       510        520        530        540        550
DSLISINADN GQLFALRALD YEALQAFEFH VGAIDQGSPA LSSQALVRVV 
       560        570        580        590        600
ILDDNDNAPF VLYPMQNASA PYTELLPRAA EPGYLVTKVV AVDRDSGQNA 
       610        620        630        640        650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHKL LVVVKDNGEP 
       660        670        680        690        700
PRSASVTLHV LLVDGFSQPF LILPEVARDP AQEDDELTLY LVIALASVSS 
       710        720        730        740        750
LFLVSVLLFV GVRLCRRARA ASPGVCFVPE EHFPGHLVDV SGAGTLSQNY 
       760        770        780 
QYEVCLTGGS GITSEFKFLS PIASNFLTES TGREIE

Length:786

Mass (Da):86,292

Last modified:December 1, 2001 - v1

Checksum:ⁱ0EA6C04986F6FA90

GO

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC020967 Genomic DNA. No translation available. AY013776 mRNA. Translation: AAK26065.1. AK038663 mRNA. Translation: BAC30087.1. CH466528 Genomic DNA. Translation: EDL10156.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_444370.1. NM_053140.3.
UniGeneⁱ	Mm.283857.

Genome annotation databases

Ensemblⁱ	ENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDⁱ	93886.
KEGGⁱ	mmu:93886.
UCSC genome browser More...UCSCⁱ	uc008eqa.1. mouse.

Similar proteinsⁱ

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:

100%	UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%	UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%	UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Cross-referencesⁱ

Sequence databases

Select the link destinations: EMBLⁱ GenBankⁱ DDBJⁱ Links Updated	AC020967 Genomic DNA. No translation available. AY013776 mRNA. Translation: AAK26065.1. AK038663 mRNA. Translation: BAC30087.1. CH466528 Genomic DNA. Translation: EDL10156.1.
NCBI Reference Sequences More...RefSeqⁱ	NP_444370.1. NM_053140.3.
UniGeneⁱ	Mm.283857.

3D structure databases

ModBaseⁱ	Search...
MobiDBⁱ	Search...

Protein-protein interaction databases

STRINGⁱ	10090.ENSMUSP00000059598.

STRINGⁱ

10090.ENSMUSP00000059598.

Protocols and materials databases

Structural Biology Knowledgebase	Search...

Structural Biology Knowledgebase

Search...

Genome annotation databases

Ensemblⁱ	ENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDⁱ	93886.
KEGGⁱ	mmu:93886.
UCSC genome browser More...UCSCⁱ	uc008eqa.1. mouse.

Organism-specific databases

CTDⁱ	56121.
MGIⁱ	MGI:2136750. Pcdhb15.

Phylogenomic databases

eggNOGⁱ	KOG3594. Eukaryota. ENOG410XQHI. LUCA.
Ensembl GeneTree More...GeneTreeⁱ	ENSGT00840000129690.
HOVERGENⁱ	HBG054878.
KEGG Orthology (KO) More...KOⁱ	K16494.
OMAⁱ	NAKMVCS.
Database of Orthologous Groups More...OrthoDBⁱ	EOG091G024L.
TreeFamⁱ	TF332299.

Miscellaneous databases

SOURCEⁱ	Search...

SOURCEⁱ

Search...

Gene expression databases

Bgeeⁱ	ENSMUSG00000047033.

Bgeeⁱ

ENSMUSG00000047033.

Family and domain databases

InterProⁱ	View protein in InterPro IPR002126. Cadherin. IPR015919. Cadherin-like. IPR032455. Cadherin_C. IPR020894. Cadherin_CS. IPR013164. Cadherin_N. IPR030741. PCDHB7.
PANTHERⁱ	PTHR24028:SF148. PTHR24028:SF148. 1 hit.
Pfam protein domain database More...Pfamⁱ	View protein in Pfam PF00028. Cadherin. 5 hits. PF08266. Cadherin_2. 1 hit. PF16492. Cadherin_C_2. 1 hit.
PRINTSⁱ	PR00205. CADHERIN.
SMARTⁱ	View protein in SMART SM00112. CA. 5 hits.
SUPFAMⁱ	SSF49313. SSF49313. 6 hits.
PROSITEⁱ	View protein in PROSITE PS00232. CADHERIN_1. 3 hits.
ProtoNetⁱ	Search...

Entry informationⁱ

Entry nameⁱ	Q91Y04_MOUSE
Accessionⁱ	Q91Y04Primary (citable) accession number: Q91Y04
Entry historyⁱ	Integrated into UniProtKB/TrEMBL:	December 1, 2001
	Last sequence update:	December 1, 2001
	Last modified:	July 5, 2017
	This is version 126 of the entry and version 1 of the sequence. See complete history.
Entry statusⁱ	Unreviewed (UniProtKB/TrEMBL)

Miscellaneousⁱ

Keywords - Technical termⁱ

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

UniProtKB

UniParc

Help

UniRef

Proteomes

Annotation systems

Supporting data

UniProtKB - Q91Y04 (Q91Y04_MOUSE)

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Protocadherin beta 15

Select a section on the left to see content.

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

Organism-specific databases

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componenti

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

Sequence databases

Genome annotation databases

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Miscellaneous databases

Gene expression databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Functionⁱ

GO - Molecular functionⁱ

GO - Biological processⁱ

Names & Taxonomyⁱ

Subcellular locationⁱ

GO - Cellular componentⁱ

PTM / Processingⁱ

Expressionⁱ

Interactionⁱ

Family & Domainsⁱ

Sequenceⁱ

Cross-referencesⁱ

Entry informationⁱ

Miscellaneousⁱ