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Protein
Submitted name:

Protein Pcdhb15

Gene

Pcdhb15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Potential calcium-dependent cell-adhesion protein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotation

Keywords - Ligandi

CalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protein Pcdhb15Imported
Submitted name:
Protocadherin beta 15Imported
Gene namesi
Name:Pcdhb15Imported
ORF Names:mCG_141293Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136750. Pcdhb15.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei687 – 710HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_500878526229 – 786Sequence analysisAdd BLAST758

Expressioni

Gene expression databases

BgeeiENSMUSG00000047033.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059598.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini27 – 133CadherinInterPro annotationAdd BLAST107
Domaini134 – 242CadherinInterPro annotationAdd BLAST109
Domaini243 – 347CadherinInterPro annotationAdd BLAST105
Domaini348 – 451CadherinInterPro annotationAdd BLAST104
Domaini452 – 561CadherinInterPro annotationAdd BLAST110
Domaini568 – 676CadherinInterPro annotationAdd BLAST109

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00840000129690.
HOVERGENiHBG054878.
KOiK16494.
OMAiYFHINVR.
OrthoDBiEOG091G024L.
TreeFamiTF332299.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR032455. Cadherin_C.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR030741. PCDHB7.
[Graphical view]
PANTHERiPTHR24028:SF69. PTHR24028:SF69. 1 hit.
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
PF16492. Cadherin_C_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91Y04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEARLEQAVQ KRQVLFLYVF LGASWASAEQ LQYSVAEETE RGTFLANLAK
60 70 80 90 100
DLGLGLGELS AREARIVSDQ NTRFLLLSPL TGELILNEKL DREELCGPTE
110 120 130 140 150
PCVLTFQLLL ERPFQIYRAA LHIKDINDNS PVFLDKEILL KISESTTPGA
160 170 180 190 200
TLLLERAQDA DVGTNSLSNY TISPNDYFHI HVHDGGEGPI IPELVLDKML
210 220 230 240 250
DREEIPEFTL TLTALDGGSP PRSGTALVQI LVLDINDNSP QFVQSLYKVQ
260 270 280 290 300
SPENTPVGSL VVAVSARDLD TGSYGQIDYT FFYATERILQ TFQINSTSGE
310 320 330 340 350
LYLKRELNYE AIQTYSITIQ ARDGGGLSGK CAVVVEVMDV NDNPPEFLLS
360 370 380 390 400
SLNSPIPENS QETVVAVFKI RDRDSGNNGK TLCSIANDLP FVLKPSVENF
410 420 430 440 450
YTLVTEKPLD RESNTEYNIT ITVTDMGIPR LTTQHTITVQ VSDINDNAPT
460 470 480 490 500
FTQTSYTMFV RENNSPALHI GTISATDSDS GSNAHITYSL RLPHDPQLAL
510 520 530 540 550
DSLISINADN GQLFALRALD YEALQAFEFH VGAIDQGSPA LSSQALVRVV
560 570 580 590 600
ILDDNDNAPF VLYPMQNASA PYTELLPRAA EPGYLVTKVV AVDRDSGQNA
610 620 630 640 650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHKL LVVVKDNGEP
660 670 680 690 700
PRSASVTLHV LLVDGFSQPF LILPEVARDP AQEDDELTLY LVIALASVSS
710 720 730 740 750
LFLVSVLLFV GVRLCRRARA ASPGVCFVPE EHFPGHLVDV SGAGTLSQNY
760 770 780
QYEVCLTGGS GITSEFKFLS PIASNFLTES TGREIE
Length:786
Mass (Da):86,292
Last modified:December 1, 2001 - v1
Checksum:i0EA6C04986F6FA90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
AY013776 mRNA. Translation: AAK26065.1.
AK038663 mRNA. Translation: BAC30087.1.
CH466528 Genomic DNA. Translation: EDL10156.1.
RefSeqiNP_444370.1. NM_053140.3.
UniGeneiMm.283857.

Genome annotation databases

EnsembliENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDi93886.
KEGGimmu:93886.
UCSCiuc008eqa.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
AY013776 mRNA. Translation: AAK26065.1.
AK038663 mRNA. Translation: BAC30087.1.
CH466528 Genomic DNA. Translation: EDL10156.1.
RefSeqiNP_444370.1. NM_053140.3.
UniGeneiMm.283857.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059598.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDi93886.
KEGGimmu:93886.
UCSCiuc008eqa.1. mouse.

Organism-specific databases

CTDi56121.
MGIiMGI:2136750. Pcdhb15.

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00840000129690.
HOVERGENiHBG054878.
KOiK16494.
OMAiYFHINVR.
OrthoDBiEOG091G024L.
TreeFamiTF332299.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047033.

Family and domain databases

Gene3Di2.60.40.60. 6 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR032455. Cadherin_C.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR030741. PCDHB7.
[Graphical view]
PANTHERiPTHR24028:SF69. PTHR24028:SF69. 1 hit.
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
PF16492. Cadherin_C_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 5 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ91Y04_MOUSE
AccessioniPrimary (citable) accession number: Q91Y04
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: November 30, 2016
This is version 119 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.