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Protein
Submitted name:

Protocadherin beta 15

Gene

Pcdhb15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin beta 15Imported
Gene namesi
Name:Pcdhb15Imported
ORF Names:mCG_141293Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136750 Pcdhb15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei687 – 710HelicalSequence analysisAdd BLAST24

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501458917229 – 786Sequence analysisAdd BLAST758

Expressioni

Gene expression databases

BgeeiENSMUSG00000047033

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059598

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 240CAInterPro annotationAdd BLAST86
Domaini264 – 345CAInterPro annotationAdd BLAST82
Domaini368 – 449CAInterPro annotationAdd BLAST82
Domaini473 – 559CAInterPro annotationAdd BLAST87
Domaini589 – 670CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594 Eukaryota
ENOG410XQHI LUCA
GeneTreeiENSGT00910000143986
HOVERGENiHBG054878
KOiK16494
OMAiNAKMVCS
OrthoDBiEOG091G024L
TreeFamiTF332299

Family and domain databases

InterProiView protein in InterPro
IPR002126 Cadherin
IPR015919 Cadherin-like
IPR032455 Cadherin_C
IPR020894 Cadherin_CS
IPR013164 Cadherin_N
IPR030741 PCDHB7
PANTHERiPTHR24028:SF69 PTHR24028:SF69, 1 hit
PfamiView protein in Pfam
PF00028 Cadherin, 5 hits
PF08266 Cadherin_2, 1 hit
PF16492 Cadherin_C_2, 1 hit
PRINTSiPR00205 CADHERIN
SMARTiView protein in SMART
SM00112 CA, 5 hits
SUPFAMiSSF49313 SSF49313, 6 hits
PROSITEiView protein in PROSITE
PS00232 CADHERIN_1, 3 hits

Sequencei

Sequence statusi: Complete.

Q91Y04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEARLEQAVQ KRQVLFLYVF LGASWASAEQ LQYSVAEETE RGTFLANLAK
60 70 80 90 100
DLGLGLGELS AREARIVSDQ NTRFLLLSPL TGELILNEKL DREELCGPTE
110 120 130 140 150
PCVLTFQLLL ERPFQIYRAA LHIKDINDNS PVFLDKEILL KISESTTPGA
160 170 180 190 200
TLLLERAQDA DVGTNSLSNY TISPNDYFHI HVHDGGEGPI IPELVLDKML
210 220 230 240 250
DREEIPEFTL TLTALDGGSP PRSGTALVQI LVLDINDNSP QFVQSLYKVQ
260 270 280 290 300
SPENTPVGSL VVAVSARDLD TGSYGQIDYT FFYATERILQ TFQINSTSGE
310 320 330 340 350
LYLKRELNYE AIQTYSITIQ ARDGGGLSGK CAVVVEVMDV NDNPPEFLLS
360 370 380 390 400
SLNSPIPENS QETVVAVFKI RDRDSGNNGK TLCSIANDLP FVLKPSVENF
410 420 430 440 450
YTLVTEKPLD RESNTEYNIT ITVTDMGIPR LTTQHTITVQ VSDINDNAPT
460 470 480 490 500
FTQTSYTMFV RENNSPALHI GTISATDSDS GSNAHITYSL RLPHDPQLAL
510 520 530 540 550
DSLISINADN GQLFALRALD YEALQAFEFH VGAIDQGSPA LSSQALVRVV
560 570 580 590 600
ILDDNDNAPF VLYPMQNASA PYTELLPRAA EPGYLVTKVV AVDRDSGQNA
610 620 630 640 650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHKL LVVVKDNGEP
660 670 680 690 700
PRSASVTLHV LLVDGFSQPF LILPEVARDP AQEDDELTLY LVIALASVSS
710 720 730 740 750
LFLVSVLLFV GVRLCRRARA ASPGVCFVPE EHFPGHLVDV SGAGTLSQNY
760 770 780
QYEVCLTGGS GITSEFKFLS PIASNFLTES TGREIE
Length:786
Mass (Da):86,292
Last modified:December 1, 2001 - v1
Checksum:i0EA6C04986F6FA90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA No translation available.
AY013776 mRNA Translation: AAK26065.1
AK038663 mRNA Translation: BAC30087.1
CH466528 Genomic DNA Translation: EDL10156.1
RefSeqiNP_444370.1, NM_053140.3
UniGeneiMm.283857

Genome annotation databases

EnsembliENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033
GeneIDi93886
KEGGimmu:93886
UCSCiuc008eqa.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ91Y04_MOUSE
AccessioniPrimary (citable) accession number: Q91Y04
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 23, 2018
This is version 136 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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