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UniProtKB - Q91Y04 (Q91Y04_MOUSE)

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Protein
Submitted name:

Protocadherin beta 15

Gene

Pcdhb15

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

Complete GO annotation...

GO - Biological processi

Complete GO annotation...

Keywordsi

Biological processCell adhesionSAAS annotation
LigandCalciumSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Protocadherin beta 15Imported
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Pcdhb15Imported
ORF Names:mCG_141293Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:2136750. Pcdhb15.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei687 – 710HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 28Sequence analysisAdd BLAST28
ChainiPRO_501051034229 – 786Sequence analysisAdd BLAST758

Expressioni

Gene expression databases

BgeeiENSMUSG00000047033.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059598.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini155 – 240CAInterPro annotationAdd BLAST86
Domaini264 – 345CAInterPro annotationAdd BLAST82
Domaini368 – 449CAInterPro annotationAdd BLAST82
Domaini473 – 559CAInterPro annotationAdd BLAST87
Domaini589 – 670CAInterPro annotationAdd BLAST82

Keywords - Domaini

RepeatSAAS annotation, SignalSequence analysis, Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00840000129690.
HOVERGENiHBG054878.
KOiK16494.
OMAiNAKMVCS.
OrthoDBiEOG091G024L.
TreeFamiTF332299.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR032455. Cadherin_C.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR030741. PCDHB7.
PANTHERiPTHR24028:SF148. PTHR24028:SF148. 1 hit.
PfamiView protein in Pfam
PF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
PF16492. Cadherin_C_2. 1 hit.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 5 hits.
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiView protein in PROSITE
PS00232. CADHERIN_1. 3 hits.

Sequencei

Sequence statusi: Complete.

Q91Y04-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEARLEQAVQ KRQVLFLYVF LGASWASAEQ LQYSVAEETE RGTFLANLAK 
        60         70         80         90        100
DLGLGLGELS AREARIVSDQ NTRFLLLSPL TGELILNEKL DREELCGPTE 
       110        120        130        140        150
PCVLTFQLLL ERPFQIYRAA LHIKDINDNS PVFLDKEILL KISESTTPGA 
       160        170        180        190        200
TLLLERAQDA DVGTNSLSNY TISPNDYFHI HVHDGGEGPI IPELVLDKML 
       210        220        230        240        250
DREEIPEFTL TLTALDGGSP PRSGTALVQI LVLDINDNSP QFVQSLYKVQ 
       260        270        280        290        300
SPENTPVGSL VVAVSARDLD TGSYGQIDYT FFYATERILQ TFQINSTSGE 
       310        320        330        340        350
LYLKRELNYE AIQTYSITIQ ARDGGGLSGK CAVVVEVMDV NDNPPEFLLS 
       360        370        380        390        400
SLNSPIPENS QETVVAVFKI RDRDSGNNGK TLCSIANDLP FVLKPSVENF 
       410        420        430        440        450
YTLVTEKPLD RESNTEYNIT ITVTDMGIPR LTTQHTITVQ VSDINDNAPT 
       460        470        480        490        500
FTQTSYTMFV RENNSPALHI GTISATDSDS GSNAHITYSL RLPHDPQLAL 
       510        520        530        540        550
DSLISINADN GQLFALRALD YEALQAFEFH VGAIDQGSPA LSSQALVRVV 
       560        570        580        590        600
ILDDNDNAPF VLYPMQNASA PYTELLPRAA EPGYLVTKVV AVDRDSGQNA 
       610        620        630        640        650
WLSFQLLKAT EPGLFSVWAH NGEVRTTRLL SERDVPKHKL LVVVKDNGEP 
       660        670        680        690        700
PRSASVTLHV LLVDGFSQPF LILPEVARDP AQEDDELTLY LVIALASVSS 
       710        720        730        740        750
LFLVSVLLFV GVRLCRRARA ASPGVCFVPE EHFPGHLVDV SGAGTLSQNY 
       760        770        780 
QYEVCLTGGS GITSEFKFLS PIASNFLTES TGREIE
Length:786
Mass (Da):86,292
Last modified:December 1, 2001 - v1
Checksum:i0EA6C04986F6FA90
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
AY013776 mRNA. Translation: AAK26065.1.
AK038663 mRNA. Translation: BAC30087.1.
CH466528 Genomic DNA. Translation: EDL10156.1.
RefSeqiNP_444370.1. NM_053140.3.
UniGeneiMm.283857.

Genome annotation databases

EnsembliENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDi93886.
KEGGimmu:93886.
UCSCiuc008eqa.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC020967 Genomic DNA. No translation available.
AY013776 mRNA. Translation: AAK26065.1.
AK038663 mRNA. Translation: BAC30087.1.
CH466528 Genomic DNA. Translation: EDL10156.1.
RefSeqiNP_444370.1. NM_053140.3.
UniGeneiMm.283857.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000059598.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000050034; ENSMUSP00000059598; ENSMUSG00000047033.
GeneIDi93886.
KEGGimmu:93886.
UCSCiuc008eqa.1. mouse.

Organism-specific databases

CTDi56121.
MGIiMGI:2136750. Pcdhb15.

Phylogenomic databases

eggNOGiKOG3594. Eukaryota.
ENOG410XQHI. LUCA.
GeneTreeiENSGT00840000129690.
HOVERGENiHBG054878.
KOiK16494.
OMAiNAKMVCS.
OrthoDBiEOG091G024L.
TreeFamiTF332299.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000047033.

Family and domain databases

InterProiView protein in InterPro
IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR032455. Cadherin_C.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
IPR030741. PCDHB7.
PANTHERiPTHR24028:SF148. PTHR24028:SF148. 1 hit.
PfamiView protein in Pfam
PF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
PF16492. Cadherin_C_2. 1 hit.
PRINTSiPR00205. CADHERIN.
SMARTiView protein in SMART
SM00112. CA. 5 hits.
SUPFAMiSSF49313. SSF49313. 6 hits.
PROSITEiView protein in PROSITE
PS00232. CADHERIN_1. 3 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ91Y04_MOUSE
AccessioniPrimary (citable) accession number: Q91Y04
Entry historyiIntegrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: June 7, 2017
This is version 125 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.