Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q91Y03

- Q91Y03_MOUSE

UniProt

Q91Y03 - Q91Y03_MOUSE

Protein
Submitted name:

MCG141291

Gene

Pcdhb16

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Dec 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain.SAAS annotation

    GO - Molecular functioni

    1. calcium ion binding Source: InterPro

    GO - Biological processi

    1. calcium-dependent cell-cell adhesion Source: UniProtKB
    2. homophilic cell adhesion Source: InterPro
    3. synapse assembly Source: UniProtKB
    4. synaptic transmission Source: UniProtKB

    Keywords - Biological processi

    Cell adhesionSAAS annotation

    Keywords - Ligandi

    CalciumUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MCG141291Imported
    Submitted name:
    Protein Pcdhb16Imported
    Submitted name:
    Protocadherin beta 16Imported
    Gene namesi
    Name:Pcdhb16Imported
    ORF Names:mCG_141291Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 18

    Organism-specific databases

    MGIiMGI:2136752. Pcdhb16.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB
    2. plasma membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Cell membraneSAAS annotation, Membrane

    Expressioni

    Gene expression databases

    GenevestigatoriQ91Y03.

    Family & Domainsi

    Sequence similaritiesi

    Contains cadherin domains.SAAS annotation

    Keywords - Domaini

    RepeatSAAS annotation, Transmembrane, Transmembrane helixSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00600000084235.
    HOVERGENiHBG054878.
    InParanoidiQ91Y03.
    KOiK16494.
    OMAiNSNFRNG.
    OrthoDBiEOG7KSX80.
    TreeFamiTF332299.

    Family and domain databases

    Gene3Di2.60.40.60. 5 hits.
    InterProiIPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    IPR013164. Cadherin_N.
    [Graphical view]
    PfamiPF00028. Cadherin. 5 hits.
    PF08266. Cadherin_2. 1 hit.
    [Graphical view]
    PRINTSiPR00205. CADHERIN.
    SMARTiSM00112. CA. 6 hits.
    [Graphical view]
    SUPFAMiSSF49313. SSF49313. 5 hits.
    PROSITEiPS00232. CADHERIN_1. 3 hits.
    PS50268. CADHERIN_2. 6 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q91Y03-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEASRKLICR QRQVLFFFLL LGFPLTTAGE LRRYSVVEEK EGRSFVTNLV    50
    KDLGLGQLEL SRRGAKVISK GNKLHLQLDQ ETGDLLLNEK VDREKLCGHT 100
    EPCLLSFQVL LDNPLDIFQA ELEVTDINDH SPEFLDKEIM LKISESSLPG 150
    ATFPLKNAQD MDVGQNGIDK YLISSNSYFR VLTRKRSDGK KYPELVLDRA 200
    LDREEEAELR LTLTAQDGGS LPRSGTTEVH IEVLDINDNA PQFEQLFYKA 250
    QIPEDSPIGF LIITVSATDK DIGVNGQISY SLFQVSDDIS KTFSIHPLTG 300
    EVRLKEHLDF EKTQSYEINI EARDAGTFSG KCTILAQVLD VNDHAPEIIL 350
    SAFTNSILEN LPETMVAVFS VSDLDSGENG KVSCSIQDDL PFFLKPSGEN 400
    FYTLLSQKPL DRESVAEYNI TITVADMGSP ILKTQVNLTV QVSDINDNAP 450
    IFTQTSYTMF IRENNSPALH IGTISATDSD SGSNAHITYS LLPPHDHQLA 500
    LASFISINAD NGQLFVLRAL DYEALQAFEF HVGATDGGSP ALSSQALVRM 550
    VVLDDNDNAP FVLYPMQNAS APYTELLPRA AEPGYLVTKV VAVDRDSGQN 600
    AWLSFQLLKA TEPGLFSVWA HNGEVHTSRL LSERDVHKHR LILLVKDNGD 650
    PPRSASVTLH VLLVDGFSQP YLPLPEVARD PDHEDSELTL YLVIALASVS 700
    SLFLVSVLLF VGVRLCRRAR EVSLGGCSVP EGHFPGHLVD VSGTGTLSQS 750
    YQYEVCLTGD SGTGEFKYLK PILPNFQDHS FRPEMGENPN SRNDWSFGIQ 800
    LK 802
    Length:802
    Mass (Da):88,738
    Last modified:December 1, 2001 - v1
    Checksum:iA28513000DBCACBE
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC020967 Genomic DNA. No translation available.
    BC116625 mRNA. Translation: AAI16626.1.
    AY013777 mRNA. Translation: AAK26066.1.
    CH466528 Genomic DNA. Translation: EDL10155.1.
    RefSeqiNP_444371.3. NM_053141.3.
    UniGeneiMm.197441.

    Genome annotation databases

    EnsembliENSMUST00000051442; ENSMUSP00000056347; ENSMUSG00000047910.
    GeneIDi93887.
    KEGGimmu:93887.
    UCSCiuc008eqb.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC020967 Genomic DNA. No translation available.
    BC116625 mRNA. Translation: AAI16626.1 .
    AY013777 mRNA. Translation: AAK26066.1 .
    CH466528 Genomic DNA. Translation: EDL10155.1 .
    RefSeqi NP_444371.3. NM_053141.3.
    UniGenei Mm.197441.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000051442 ; ENSMUSP00000056347 ; ENSMUSG00000047910 .
    GeneIDi 93887.
    KEGGi mmu:93887.
    UCSCi uc008eqb.1. mouse.

    Organism-specific databases

    CTDi 57717.
    MGIi MGI:2136752. Pcdhb16.

    Phylogenomic databases

    GeneTreei ENSGT00600000084235.
    HOVERGENi HBG054878.
    InParanoidi Q91Y03.
    KOi K16494.
    OMAi NSNFRNG.
    OrthoDBi EOG7KSX80.
    TreeFami TF332299.

    Miscellaneous databases

    NextBioi 351817.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q91Y03.

    Family and domain databases

    Gene3Di 2.60.40.60. 5 hits.
    InterProi IPR002126. Cadherin.
    IPR015919. Cadherin-like.
    IPR020894. Cadherin_CS.
    IPR013164. Cadherin_N.
    [Graphical view ]
    Pfami PF00028. Cadherin. 5 hits.
    PF08266. Cadherin_2. 1 hit.
    [Graphical view ]
    PRINTSi PR00205. CADHERIN.
    SMARTi SM00112. CA. 6 hits.
    [Graphical view ]
    SUPFAMi SSF49313. SSF49313. 5 hits.
    PROSITEi PS00232. CADHERIN_1. 3 hits.
    PS50268. CADHERIN_2. 6 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."
      Wu Q., Maniatis T.
      Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.
    2. "Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
      Wu Q., Maniatis T.
      Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.
    3. "Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
      Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
      Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Tissue: BrainImported.
    4. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: PCR rescued clonesImported.
    6. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    8. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ91Y03_MOUSE
    AccessioniPrimary (citable) accession number: Q91Y03
    Entry historyi
    Integrated into UniProtKB/TrEMBL: December 1, 2001
    Last sequence update: December 1, 2001
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3