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Q91Y03 (Q91Y03_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Protein Pcdhb16 Ensembl ENSMUSP00000056347

Protocadherin beta 16 EMBL AAK26066.1
Gene names
Name:Pcdhb16 MGI 2136752 Ensembl ENSMUSP00000056347 EMBL AAI16626.1
ORF Names:mCG_141291 EMBL EDL10155.1
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length802 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain By similarity. SAAS SAAS015919

Sequence similarities

Contains cadherin domains. SAAS SAAS015919

Sequences

Sequence LengthMass (Da)Tools
Q91Y03 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: A28513000DBCACBE

FASTA80288,738
        10         20         30         40         50         60 
MEASRKLICR QRQVLFFFLL LGFPLTTAGE LRRYSVVEEK EGRSFVTNLV KDLGLGQLEL 

        70         80         90        100        110        120 
SRRGAKVISK GNKLHLQLDQ ETGDLLLNEK VDREKLCGHT EPCLLSFQVL LDNPLDIFQA 

       130        140        150        160        170        180 
ELEVTDINDH SPEFLDKEIM LKISESSLPG ATFPLKNAQD MDVGQNGIDK YLISSNSYFR 

       190        200        210        220        230        240 
VLTRKRSDGK KYPELVLDRA LDREEEAELR LTLTAQDGGS LPRSGTTEVH IEVLDINDNA 

       250        260        270        280        290        300 
PQFEQLFYKA QIPEDSPIGF LIITVSATDK DIGVNGQISY SLFQVSDDIS KTFSIHPLTG 

       310        320        330        340        350        360 
EVRLKEHLDF EKTQSYEINI EARDAGTFSG KCTILAQVLD VNDHAPEIIL SAFTNSILEN 

       370        380        390        400        410        420 
LPETMVAVFS VSDLDSGENG KVSCSIQDDL PFFLKPSGEN FYTLLSQKPL DRESVAEYNI 

       430        440        450        460        470        480 
TITVADMGSP ILKTQVNLTV QVSDINDNAP IFTQTSYTMF IRENNSPALH IGTISATDSD 

       490        500        510        520        530        540 
SGSNAHITYS LLPPHDHQLA LASFISINAD NGQLFVLRAL DYEALQAFEF HVGATDGGSP 

       550        560        570        580        590        600 
ALSSQALVRM VVLDDNDNAP FVLYPMQNAS APYTELLPRA AEPGYLVTKV VAVDRDSGQN 

       610        620        630        640        650        660 
AWLSFQLLKA TEPGLFSVWA HNGEVHTSRL LSERDVHKHR LILLVKDNGD PPRSASVTLH 

       670        680        690        700        710        720 
VLLVDGFSQP YLPLPEVARD PDHEDSELTL YLVIALASVS SLFLVSVLLF VGVRLCRRAR 

       730        740        750        760        770        780 
EVSLGGCSVP EGHFPGHLVD VSGTGTLSQS YQYEVCLTGD SGTGEFKYLK PILPNFQDHS 

       790        800 
FRPEMGENPN SRNDWSFGIQ LK 

« Hide

References

« Hide 'large scale' references
[1]"A striking organization of a large family of human neural cadherin-like cell adhesion genes."
Wu Q., Maniatis T.
Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26066.1.
[2]"Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
Wu Q., Maniatis T.
Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26066.1.
[3]"Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26066.1.
[4]"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. expand/collapse author list , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL10155.1.
[5]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: PCR rescued clones EMBL AAI16626.1.
[6]Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: Mixed EMBL EDL10155.1.
[7]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000056347.
[8]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000056347.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC020967 Genomic DNA. No translation available.
BC116625 mRNA. Translation: AAI16626.1.
AY013777 mRNA. Translation: AAK26066.1.
CH466528 Genomic DNA. Translation: EDL10155.1.
RefSeqNP_444371.3. NM_053141.3.
UniGeneMm.197441.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000051442; ENSMUSP00000056347; ENSMUSG00000047910.
GeneID93887.
KEGGmmu:93887.
UCSCuc008eqb.1. mouse.

Organism-specific databases

CTD57717.
MGIMGI:2136752. Pcdhb16.

Phylogenomic databases

GeneTreeENSGT00600000084235.
HOVERGENHBG054878.
InParanoidQ91Y03.
KOK16494.
OMANSNFRNG.
OrthoDBEOG7KSX80.
TreeFamTF332299.

Gene expression databases

GenevestigatorQ91Y03.

Family and domain databases

Gene3D2.60.40.60. 5 hits.
InterProIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSPR00205. CADHERIN.
SMARTSM00112. CA. 6 hits.
[Graphical view]
SUPFAMSSF49313. SSF49313. 5 hits.
PROSITEPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio351817.
SOURCESearch...

Entry information

Entry nameQ91Y03_MOUSE
AccessionPrimary (citable) accession number: Q91Y03
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)