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Q91Y03

- Q91Y03_MOUSE

UniProt

Q91Y03 - Q91Y03_MOUSE

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Protein
Submitted name:

MCG141291

Gene
Pcdhb16, mCG_141291
Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Functioni

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain By similarity.SAAS annotations

GO - Molecular functioni

  1. calcium ion binding Source: InterPro

GO - Biological processi

  1. calcium-dependent cell-cell adhesion Source: UniProtKB
  2. homophilic cell adhesion Source: InterPro
  3. synapse assembly Source: UniProtKB
  4. synaptic transmission Source: UniProtKB
Complete GO annotation...

Keywords - Biological processi

Cell adhesionSAAS annotations

Keywords - Ligandi

CalciumUniRule annotationSAAS annotations

Names & Taxonomyi

Protein namesi
Submitted name:
MCG141291Imported
Submitted name:
Protein Pcdhb16Imported
Submitted name:
Protocadherin beta 16Imported
Gene namesi
Name:Pcdhb16Imported
ORF Names:mCG_141291Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 18

Organism-specific databases

MGIiMGI:2136752. Pcdhb16.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB
  2. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotations, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ91Y03.

Family & Domainsi

Sequence similaritiesi

Contains cadherin domains.SAAS annotations

Keywords - Domaini

RepeatSAAS annotations, Transmembrane, Transmembrane helixSAAS annotations

Phylogenomic databases

GeneTreeiENSGT00600000084235.
HOVERGENiHBG054878.
InParanoidiQ91Y03.
KOiK16494.
OMAiNSNFRNG.
OrthoDBiEOG7KSX80.
TreeFamiTF332299.

Family and domain databases

Gene3Di2.60.40.60. 5 hits.
InterProiIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamiPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSiPR00205. CADHERIN.
SMARTiSM00112. CA. 6 hits.
[Graphical view]
SUPFAMiSSF49313. SSF49313. 5 hits.
PROSITEiPS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q91Y03-1 [UniParc]FASTAAdd to Basket

« Hide

MEASRKLICR QRQVLFFFLL LGFPLTTAGE LRRYSVVEEK EGRSFVTNLV    50
KDLGLGQLEL SRRGAKVISK GNKLHLQLDQ ETGDLLLNEK VDREKLCGHT 100
EPCLLSFQVL LDNPLDIFQA ELEVTDINDH SPEFLDKEIM LKISESSLPG 150
ATFPLKNAQD MDVGQNGIDK YLISSNSYFR VLTRKRSDGK KYPELVLDRA 200
LDREEEAELR LTLTAQDGGS LPRSGTTEVH IEVLDINDNA PQFEQLFYKA 250
QIPEDSPIGF LIITVSATDK DIGVNGQISY SLFQVSDDIS KTFSIHPLTG 300
EVRLKEHLDF EKTQSYEINI EARDAGTFSG KCTILAQVLD VNDHAPEIIL 350
SAFTNSILEN LPETMVAVFS VSDLDSGENG KVSCSIQDDL PFFLKPSGEN 400
FYTLLSQKPL DRESVAEYNI TITVADMGSP ILKTQVNLTV QVSDINDNAP 450
IFTQTSYTMF IRENNSPALH IGTISATDSD SGSNAHITYS LLPPHDHQLA 500
LASFISINAD NGQLFVLRAL DYEALQAFEF HVGATDGGSP ALSSQALVRM 550
VVLDDNDNAP FVLYPMQNAS APYTELLPRA AEPGYLVTKV VAVDRDSGQN 600
AWLSFQLLKA TEPGLFSVWA HNGEVHTSRL LSERDVHKHR LILLVKDNGD 650
PPRSASVTLH VLLVDGFSQP YLPLPEVARD PDHEDSELTL YLVIALASVS 700
SLFLVSVLLF VGVRLCRRAR EVSLGGCSVP EGHFPGHLVD VSGTGTLSQS 750
YQYEVCLTGD SGTGEFKYLK PILPNFQDHS FRPEMGENPN SRNDWSFGIQ 800
LK 802
Length:802
Mass (Da):88,738
Last modified:December 1, 2001 - v1
Checksum:iA28513000DBCACBE
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC020967 Genomic DNA. No translation available.
BC116625 mRNA. Translation: AAI16626.1.
AY013777 mRNA. Translation: AAK26066.1.
CH466528 Genomic DNA. Translation: EDL10155.1.
RefSeqiNP_444371.3. NM_053141.3.
UniGeneiMm.197441.

Genome annotation databases

EnsembliENSMUST00000051442; ENSMUSP00000056347; ENSMUSG00000047910.
GeneIDi93887.
KEGGimmu:93887.
UCSCiuc008eqb.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AC020967 Genomic DNA. No translation available.
BC116625 mRNA. Translation: AAI16626.1 .
AY013777 mRNA. Translation: AAK26066.1 .
CH466528 Genomic DNA. Translation: EDL10155.1 .
RefSeqi NP_444371.3. NM_053141.3.
UniGenei Mm.197441.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000051442 ; ENSMUSP00000056347 ; ENSMUSG00000047910 .
GeneIDi 93887.
KEGGi mmu:93887.
UCSCi uc008eqb.1. mouse.

Organism-specific databases

CTDi 57717.
MGIi MGI:2136752. Pcdhb16.

Phylogenomic databases

GeneTreei ENSGT00600000084235.
HOVERGENi HBG054878.
InParanoidi Q91Y03.
KOi K16494.
OMAi NSNFRNG.
OrthoDBi EOG7KSX80.
TreeFami TF332299.

Miscellaneous databases

NextBioi 351817.
SOURCEi Search...

Gene expression databases

Genevestigatori Q91Y03.

Family and domain databases

Gene3Di 2.60.40.60. 5 hits.
InterProi IPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view ]
Pfami PF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view ]
PRINTSi PR00205. CADHERIN.
SMARTi SM00112. CA. 6 hits.
[Graphical view ]
SUPFAMi SSF49313. SSF49313. 5 hits.
PROSITEi PS00232. CADHERIN_1. 3 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "A striking organization of a large family of human neural cadherin-like cell adhesion genes."
    Wu Q., Maniatis T.
    Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  2. "Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
    Wu Q., Maniatis T.
    Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  3. "Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
    Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
    Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Tissue: BrainImported.
  4. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
    Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
    , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
    Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
    , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: PCR rescued clonesImported.
  6. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: MixedImported.
  7. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6JImported.
  8. Ensembl
    Submitted (FEB-2012) to UniProtKB
    Cited for: IDENTIFICATION.
    Strain: C57BL/6JImported.

Entry informationi

Entry nameiQ91Y03_MOUSE
AccessioniPrimary (citable) accession number: Q91Y03
Entry historyi
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: February 19, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi