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Q91XY7 (Q91XY7_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 94. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names

Protocadherin gamma A12 EMBL AAK26084.1

Protocadherin gamma subfamily A, 12 EMBL AAH54528.1
Gene names
Name:Pcdhga12 EMBL AAH54528.1
Synonyms:Pcdhgb6 Ensembl ENSMUSP00000036359
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length932 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Potential calcium-dependent cell-adhesion protein. May be involved in the establishment and maintenance of specific neuronal connections in the brain By similarity. SAAS SAAS002126

Sequence similarities

Contains cadherin domains. SAAS SAAS013164

Sequences

Sequence LengthMass (Da)Tools
Q91XY7 [UniParc].

Last modified December 1, 2001. Version 1.
Checksum: 2FA4348E600D0575

FASTA932100,834
        10         20         30         40         50         60 
MIPMQRREDC KGLVFLGVLL GMLWKAGSTQ IRYSVPEELE KGSRVGNISK DLGLEPRELE 

        70         80         90        100        110        120 
KRGVRIVSRG RAQLFALNPR SGSLVTAGRI DREELCMGSI KCQLNLEILM EDIGKIYGVE 

       130        140        150        160        170        180 
IEVRDINDNA PYFRESELEI KMSENAAAGM RFPLPHAWDP DIGKNSLQSY QLSPNAHFSL 

       190        200        210        220        230        240 
EVQNGADGNK YPELVLESSL DREEKAAHLL VLTASDAGDP VRTGTARIRV MVVDANDNAP 

       250        260        270        280        290        300 
AFARSEYRVS VRENVAVGTQ LLLVNATDPD EGANAEVIYS FRYVDDKAAK VFKLDSNLGT 

       310        320        330        340        350        360 
ISTIGELNHE ESGFYEMEVQ ATDNAGYSAR AKVLVTVLDV NDNAPEVAIT SLTNSVPENS 

       370        380        390        400        410        420 
PQGTLIALLN VNDQDSGENG QVICSIQENL PFKLEKSYGN YYRLVTDAVL DREEVPSYNI 

       430        440        450        460        470        480 
TMTATDRGSP PLTTETHLAL DIADTNDNSP VFLQASYWAY IPENNPRGAS IASVTAHDPD 

       490        500        510        520        530        540 
SDKNAQVTYS LAEDTHQGVP LSSYVSINSD TGVLYALHSF DYEQFPDLQL QVIARDSGDP 

       550        560        570        580        590        600 
PLSSNVSLSL FVLDQNDNVP EILYPTLPTD GSTGVELAPR SAEPGYLVTK VVAVDRDSGQ 

       610        620        630        640        650        660 
NAWLSYRLLK ASEPGLFSVG LHTGEISTAR ALMDRDALKQ NLVVSVQDHG QPPLSATVTL 

       670        680        690        700        710        720 
TVAIADSIPD VLADLDNLES PSTSETSGLT LYLVVAVAAV STVFLVFVLV LLALRLRRWH 

       730        740        750        760        770        780 
SLRLLRAGGP GLADVAASHF VGVDGVQAFL QTYSHEVSLT AGSRKSHLIF PQPNYADTLI 

       790        800        810        820        830        840 
SQESCEKTEP LLPSGDSVFS KDNHALNQQA PPNTDWRFSQ AQRPGTSGSQ NGDETGTWPN 

       850        860        870        880        890        900 
NQFDTEMLQA MILASASEAA DGSSTLGGGA GTMGLSARYG PQFTLQHVPD YRQNVYIPGS 

       910        920        930 
NATLTNAAGK RDGKAPAGGN GNKKKSGKKE KK 

« Hide

References

« Hide 'large scale' references
[1]"A striking organization of a large family of human neural cadherin-like cell adhesion genes."
Wu Q., Maniatis T.
Cell 97:779-790(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26084.1.
[2]"Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes."
Wu Q., Maniatis T.
Proc. Natl. Acad. Sci. U.S.A. 97:3124-3129(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26084.1.
[3]"Comparative DNA sequence analysis of mouse and human protocadherin gene clusters."
Wu Q., Zhang T., Cheng J.-F., Kim Y., Grimwood J., Schmutz J., Dickson M., Noonan J.P., Zhang M.Q., Myers R.M., Maniatis T.
Genome Res. 11:389-404(2001) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Tissue: Brain EMBL AAK26084.1.
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M. expand/collapse author list , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6 EMBL AAH54528.1.
Tissue: Brain EMBL AAH54528.1.
[5]"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. expand/collapse author list , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P.
PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C57BL/6J Ensembl ENSMUSP00000036359.
[6]Ensembl
Submitted (FEB-2012) to UniProtKB
Cited for: IDENTIFICATION.
Strain: C57BL/6J Ensembl ENSMUSP00000036359.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AC020971 Genomic DNA. No translation available.
AC129315 Genomic DNA. No translation available.
BC054528 mRNA. Translation: AAH54528.1.
BC056998 mRNA. Translation: AAH56998.1.
AY013795 mRNA. Translation: AAK26084.1.
RefSeqNP_291073.1. NM_033595.4.
UniGeneMm.247203.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000044851; ENSMUSP00000036359; ENSMUSG00000023036.
GeneID93724.
KEGGmmu:93724.
UCSCuc008erd.1. mouse.

Organism-specific databases

CTD26025.
MGIMGI:1935197. Pcdhgb6.

Phylogenomic databases

GeneTreeENSGT00750000117438.
HOGENOMHOG000220892.
HOVERGENHBG054878.
KOK16495.
OMALLMAWIC.

Gene expression databases

GenevestigatorQ91XY7.

Family and domain databases

Gene3D2.60.40.60. 6 hits.
InterProIPR002126. Cadherin.
IPR015919. Cadherin-like.
IPR020894. Cadherin_CS.
IPR013164. Cadherin_N.
[Graphical view]
PfamPF00028. Cadherin. 5 hits.
PF08266. Cadherin_2. 1 hit.
[Graphical view]
PRINTSPR00205. CADHERIN.
SMARTSM00112. CA. 6 hits.
[Graphical view]
SUPFAMSSF49313. SSF49313. 6 hits.
PROSITEPS00232. CADHERIN_1. 5 hits.
PS50268. CADHERIN_2. 6 hits.
[Graphical view]
ProtoNetSearch...

Other

NextBio351555.
SOURCESearch...

Entry information

Entry nameQ91XY7_MOUSE
AccessionPrimary (citable) accession number: Q91XY7
Entry history
Integrated into UniProtKB/TrEMBL: December 1, 2001
Last sequence update: December 1, 2001
Last modified: May 14, 2014
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)